Acetyl-d-carnitine is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Acetyl-d-carnitine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Proteostasis Deficiencies | D057165 | 5 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Coronary Artery Disease | D003324 | 47 associated lipids |
| Cleft Lip | D002971 | 8 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Amino Acid Metabolism, Inborn Errors | D000592 | 16 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ori C et al. | Effects of acetyl-L-carnitine on regional cerebral glucose metabolism in awake rats. | 2002 | Brain Res. | pmid:12270513 |
| Sharman EH et al. | Reversal of biochemical and behavioral parameters of brain aging by melatonin and acetyl L-carnitine. | 2002 | Brain Res. | pmid:12445964 |
| Roberts PA et al. | The temporal relationship between glycogen phosphorylase and activation of the pyruvate dehydrogenase complex during adrenaline infusion in resting canine skeletal muscle. | 2002 | J. Physiol. (Lond.) | pmid:12433969 |
| Tolu P et al. | Effects of long-term acetyl-L-carnitine administration in rats: I. increased dopamine output in mesocorticolimbic areas and protection toward acute stress exposure. | 2002 | Neuropsychopharmacology | pmid:12225698 |
| Pop-Busui R et al. | Dissection of metabolic, vascular, and nerve conduction interrelationships in experimental diabetic neuropathy by cyclooxygenase inhibition and acetyl-L-carnitine administration. | 2002 | Diabetes | pmid:12145179 |
| Graziano F et al. | Potential role of levocarnitine supplementation for the treatment of chemotherapy-induced fatigue in non-anaemic cancer patients. | 2002 | Br. J. Cancer | pmid:12085175 |
| Chiechio S et al. | L-Acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors. | 2002 | Mol. Pharmacol. | pmid:11961116 |
| Iossa S et al. | Acetyl-L-carnitine supplementation differently influences nutrient partitioning, serum leptin concentration and skeletal muscle mitochondrial respiration in young and old rats. | 2002 | J. Nutr. | pmid:11925454 |
| Liu J et al. | Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites. | 2002 | Ann. N. Y. Acad. Sci. | pmid:11976193 |
| Hagen TM et al. | Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid. | 2002 | Ann. N. Y. Acad. Sci. | pmid:11976222 |
| Watt MJ et al. | Carbohydrate ingestion reduces skeletal muscle acetylcarnitine availability but has no effect on substrate phosphorylation at the onset of exercise in man. | 2002 | J. Physiol. (Lond.) | pmid:12411537 |
| Watt MJ et al. | Intramuscular triacylglycerol, glycogen and acetyl group metabolism during 4 h of moderate exercise in man. | 2002 | J. Physiol. (Lond.) | pmid:12068055 |
| Tyni T et al. | Analysis of mitochondrial fatty acid oxidation intermediates by tandem mass spectrometry from intact mitochondria prepared from homogenates of cultured fibroblasts, skeletal muscle cells, and fresh muscle. | 2002 | Pediatr. Res. | pmid:12084849 |
| Defani MA et al. | Effect of acetyl-L-carnitine on VIP-ergic neurons in the jejunum submucous plexus of diabetic rats. | 2003 | Arq Neuropsiquiatr | pmid:14762599 |
| Pisano C et al. | Paclitaxel and Cisplatin-induced neurotoxicity: a protective role of acetyl-L-carnitine. | 2003 | Clin. Cancer Res. | pmid:14654561 |
| Pascale E et al. | Modulation of methylation in the FMR1 promoter region after long term treatment with L-carnitine and acetyl-L-carnitine. | 2003 | J. Med. Genet. | pmid:12807975 |
| Masi F et al. | Effects of long-term acetyl-L-carnitine administration in rats--II: Protection against the disrupting effect of stress on the acquisition of appetitive behavior. | 2003 | Neuropsychopharmacology | pmid:12655313 |
| Mattei B et al. | Pharmacologically induced enhancement of recurrent inhibition in humans: effects on motoneurone discharge patterns. | 2003 | J. Physiol. (Lond.) | pmid:12611926 |
| Arafa HM and Sayed-Ahmed MM | Protective role of carnitine esters against alcohol-induced gastric lesions in rats. | 2003 | Pharmacol. Res. | pmid:12860448 |
| Cui J et al. | Effects of L-carnitine and its derivatives on postischemic cardiac function, ventricular fibrillation and necrotic and apoptotic cardiomyocyte death in isolated rat hearts. | 2003 | Mol. Cell. Biochem. | pmid:14674702 |
| Beal MF | Bioenergetic approaches for neuroprotection in Parkinson's disease. | 2003 | Ann. Neurol. | pmid:12666097 |
| Feher J et al. | Mitotropic compounds for the treatment of age-related macular degeneration. The metabolic approach and a pilot study. | 2003 Sep-Oct | Ophthalmologica | pmid:12913326 |
| Evans AM et al. | Impact of hemodialysis on endogenous plasma and muscle carnitine levels in patients with end-stage renal disease. | 2004 | Kidney Int. | pmid:15458447 |
| Leblanc PJ et al. | Effects of 7 wk of endurance training on human skeletal muscle metabolism during submaximal exercise. | 2004 | J. Appl. Physiol. | pmid:15220302 |
| Tanaka Y et al. | Acetyl-L-carnitine supplementation restores decreased tissue carnitine levels and impaired lipid metabolism in aged rats. | 2004 | J. Lipid Res. | pmid:14703509 |
| Ames BN and Liu J | Delaying the mitochondrial decay of aging with acetylcarnitine. | 2004 | Ann. N. Y. Acad. Sci. | pmid:15591008 |
| Bastianetto S and Quirion R | Natural antioxidants and neurodegenerative diseases. | 2004 | Front. Biosci. | pmid:15353369 |
| Ames BN | Delaying the mitochondrial decay of aging. | 2004 | Ann. N. Y. Acad. Sci. | pmid:15247055 |
| Vermeulen RC and Scholte HR | Exploratory open label, randomized study of acetyl- and propionylcarnitine in chronic fatigue syndrome. | 2004 Mar-Apr | Psychosom Med | pmid:15039515 |
| Cavallini G et al. | Cinnoxicam and L-carnitine/acetyl-L-carnitine treatment for idiopathic and varicocele-associated oligoasthenospermia. | 2004 Sep-Oct | J. Androl. | pmid:15292108 |
| Bianchi G et al. | Symptomatic and neurophysiological responses of paclitaxel- or cisplatin-induced neuropathy to oral acetyl-L-carnitine. | 2005 | Eur. J. Cancer | pmid:16039110 |
| Kobayashi D et al. | Carnitine/organic cation transporter OCTN2-mediated transport of carnitine in primary-cultured epididymal epithelial cells. | 2005 | Reproduction | pmid:16322553 |
| Zanelli SA et al. | Mechanisms of ischemic neuroprotection by acetyl-L-carnitine. | 2005 | Ann. N. Y. Acad. Sci. | pmid:16179519 |
| Pracharoenwattana I et al. | Arabidopsis peroxisomal citrate synthase is required for fatty acid respiration and seed germination. | 2005 | Plant Cell | pmid:15923350 |
| Tabolacci E et al. | Differential epigenetic modifications in the FMR1 gene of the fragile X syndrome after reactivating pharmacological treatments. | 2005 | Eur. J. Hum. Genet. | pmid:15741991 |
| Kasumov T et al. | Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver. | 2005 | Biochem. J. | pmid:15773815 |
| Bian F et al. | Peroxisomal and mitochondrial oxidation of fatty acids in the heart, assessed from the 13C labeling of malonyl-CoA and the acetyl moiety of citrate. | 2005 | J. Biol. Chem. | pmid:15611129 |
| Roberts PA et al. | Acetyl-CoA provision and the acetyl group deficit at the onset of contraction in ischemic canine skeletal muscle. | 2005 | Am. J. Physiol. Endocrinol. Metab. | pmid:15454400 |
| Peluso G et al. | Differential carnitine/acylcarnitine translocase expression defines distinct metabolic signatures in skeletal muscle cells. | 2005 | J. Cell. Physiol. | pmid:15515015 |
| Cavallini G et al. | Acetyl-L-carnitine plus propionyl-L-carnitine improve efficacy of sildenafil in treatment of erectile dysfunction after bilateral nerve-sparing radical retropubic prostatectomy. | 2005 | Urology | pmid:16286128 |
| Roepstorff C et al. | Malonyl-CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exercise. | 2005 | Am. J. Physiol. Endocrinol. Metab. | pmid:15383373 |
| Szutowicz A et al. | Nerve growth factor and acetyl-L-carnitine evoked shifts in acetyl-CoA and cholinergic SN56 cell vulnerability to neurotoxic inputs. | 2005 Jan 1-15 | J. Neurosci. Res. | pmid:15558747 |
| Ghirardi O et al. | Acetyl-L-Carnitine prevents and reverts experimental chronic neurotoxicity induced by oxaliplatin, without altering its antitumor properties. | 2005 Jul-Aug | Anticancer Res. | pmid:16080512 |
| Feher J et al. | Improvement of visual functions and fundus alterations in early age-related macular degeneration treated with a combination of acetyl-L-carnitine, n-3 fatty acids, and coenzyme Q10. | 2005 May-Jun | Ophthalmologica | pmid:15947501 |
| Ghirardi O et al. | Chemotherapy-induced allodinia: neuroprotective effect of acetyl-L-carnitine. | 2005 May-Jun | In Vivo | pmid:15875786 |
| Ferraresi R et al. | Protective effect of acetyl-L-carnitine against oxidative stress induced by antiretroviral drugs. | 2006 | FEBS Lett. | pmid:17118360 |
| Chiechio S et al. | Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-kappaB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine. | 2006 | Mol Pain | pmid:16764720 |
| Jensen MV et al. | Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion. | 2006 | J. Biol. Chem. | pmid:16740637 |
| Gago MF et al. | SANDO: two novel mutations in POLG1 gene. | 2006 | Neuromuscul. Disord. | pmid:16919951 |
| Hack A et al. | Monitoring of ketogenic diet for carnitine metabolites by subcutaneous microdialysis. | 2006 | Pediatr. Res. | pmid:16690958 |