Acetyl-d-carnitine is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Acetyl-d-carnitine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Amino Acid Metabolism, Inborn Errors | D000592 | 16 associated lipids |
| Coronary Artery Disease | D003324 | 47 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Cleft Lip | D002971 | 8 associated lipids |
| Proteostasis Deficiencies | D057165 | 5 associated lipids |
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Jiang Q et al. | Oral acetyl-L-carnitine treatment in hepatic encephalopathy: view of evidence-based medicine. | 2013 Sep-Oct | Ann Hepatol | pmid:24018499 |
| Yergey AL et al. | Thermospray liquid chromatography/mass spectrometry for the analysis of L-carnitine and its short-chain acyl derivatives. | 1984 | Anal. Biochem. | pmid:6476364 |
| Minkler PE and Hoppel CL | Quantification of free carnitine, individual short- and medium-chain acylcarnitines, and total carnitine in plasma by high-performance liquid chromatography. | 1993 | Anal. Biochem. | pmid:8214594 |
| Emaus R and Bieber LL | Preparation of radioactive acetyl-L-carnitine by an enzymatic exchange reaction. | 1982 | Anal. Biochem. | pmid:6122386 |
| Kamimori H et al. | Determination of carnitine and saturated-acyl group carnitines in human urine by high-performance liquid chromatography with fluorescence detection. | 1994 | Anal. Biochem. | pmid:8074302 |
| Morand R et al. | Quantification of plasma carnitine and acylcarnitines by high-performance liquid chromatography-tandem mass spectrometry using online solid-phase extraction. | 2013 | Anal Bioanal Chem | pmid:23995505 |
| Fisher JS et al. | Activation of AMP kinase enhances sensitivity of muscle glucose transport to insulin. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:11739078 |
| Schooneman MG et al. | Transorgan fluxes in a porcine model reveal a central role for liver in acylcarnitine metabolism. | 2015 | Am. J. Physiol. Endocrinol. Metab. | pmid:26037250 |
| Roberts PA et al. | Acetyl-CoA provision and the acetyl group deficit at the onset of contraction in ischemic canine skeletal muscle. | 2005 | Am. J. Physiol. Endocrinol. Metab. | pmid:15454400 |
| Evans MK et al. | Effects of acetate infusion and hyperoxia on muscle substrate phosphorylation after onset of moderate exercise. | 2001 | Am. J. Physiol. Endocrinol. Metab. | pmid:11701427 |
| Starritt EC et al. | Sensitivity of CPT I to malonyl-CoA in trained and untrained human skeletal muscle. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:10710500 |
| Roepstorff C et al. | Malonyl-CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exercise. | 2005 | Am. J. Physiol. Endocrinol. Metab. | pmid:15383373 |
| St Amand TA et al. | Pyruvate overrides inhibition of PDH during exercise after a low-carbohydrate diet. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:10913026 |
| Parolin ML et al. | Regulation of skeletal muscle glycogen phosphorylase and PDH during maximal intermittent exercise. | 1999 | Am. J. Physiol. | pmid:10567017 |
| Renstrom B et al. | Mechanisms of substrate preference for oxidative metabolism during early myocardial reperfusion. | 1990 | Am. J. Physiol. | pmid:2386216 |
| Timmons JA et al. | Metabolic responses from rest to steady state determine contractile function in ischemic skeletal muscle. | 1997 | Am. J. Physiol. | pmid:9277374 |
| Owens K et al. | Effects of fatty acid intermediates on Na+-K+-ATPase activity of cardiac sarcolemma. | 1982 | Am. J. Physiol. | pmid:6278956 |
| Pande SV et al. | Protective role of adenine nucleotide translocase in O2-deficient hearts. | 1984 | Am. J. Physiol. | pmid:6331205 |
| Putman CT et al. | Pyruvate dehydrogenase activation in inactive muscle during and after maximal exercise in men. | 1999 | Am. J. Physiol. | pmid:10070014 |
| Howlett RA et al. | Regulation of skeletal muscle glycogen phosphorylase and PDH at varying exercise power outputs. | 1998 | Am. J. Physiol. | pmid:9688676 |
| Pomponi MG and Neri G | Butyrate and acetyl-carnitine inhibit the cytogenetic expression of the fragile X in vitro. | 1994 | Am. J. Med. Genet. | pmid:7943015 |
| Malaguarnera M et al. | Oral acetyl-L-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. | 2011 | Am. J. Clin. Nutr. | pmid:21310833 |
| O'Sullivan A et al. | Dietary intake patterns are reflected in metabolomic profiles: potential role in dietary assessment studies. | 2011 | Am. J. Clin. Nutr. | pmid:21177801 |
| El Banani H et al. | Ionic and metabolic imbalance as potential factors of ischemia reperfusion injury. | 1998 | Am. J. Cardiol. | pmid:9737483 |
| Seidman MD et al. | Biologic activity of mitochondrial metabolites on aging and age-related hearing loss. | 2000 | Am J Otol | pmid:10733178 |
| Acetyl-L-carnitine. | 1999 | Altern Med Rev | pmid:10608918 | |
| Kidd PM | A review of nutrients and botanicals in the integrative management of cognitive dysfunction. | 1999 | Altern Med Rev | pmid:10383479 |
| Acetyl-L-carnitine. Monograph. | 2010 | Altern Med Rev | pmid:20359271 | |
| Adamo S et al. | Effect of L-carnitine on ethanol and acetate plasma levels after oral administration of ethanol in humans. | 1988 | Alcohol. Clin. Exp. Res. | pmid:3067610 |
| Milazzo L et al. | Effect of antioxidants on mitochondrial function in HIV-1-related lipoatrophy: a pilot study. | 2010 | AIDS Res. Hum. Retroviruses | pmid:20977356 |
| Palermo V et al. | Acetyl-L-carnitine protects yeast cells from apoptosis and aging and inhibits mitochondrial fission. | 2010 | Aging Cell | pmid:20550520 |
| Rosca MG et al. | Mitochondria in the elderly: Is acetylcarnitine a rejuvenator? | 2009 | Adv. Drug Deliv. Rev. | pmid:19720100 |
| Bigford GE and Del Rossi G | Supplemental substances derived from foods as adjunctive therapeutic agents for treatment of neurodegenerative diseases and disorders. | 2014 | Adv Nutr | pmid:25022989 |
| Sahlin K | Muscle carnitine metabolism during incremental dynamic exercise in humans. | 1990 | Acta Physiol. Scand. | pmid:2327259 |
| Sakuma T et al. | The urinary acylcarnitine profile in three cases of transient hyperammonemia of the newborn. | 1992 | Acta Paediatr. | pmid:1498512 |
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