Acetyl-d-carnitine is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Acetyl-d-carnitine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Amino Acid Metabolism, Inborn Errors | D000592 | 16 associated lipids |
| Coronary Artery Disease | D003324 | 47 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Cleft Lip | D002971 | 8 associated lipids |
| Proteostasis Deficiencies | D057165 | 5 associated lipids |
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lindquist C et al. | Increased hepatic mitochondrial FA oxidation reduces plasma and liver TG levels and is associated with regulation of UCPs and APOC-III in rats. | 2017 | J. Lipid Res. | pmid:28473603 |
| Yu M et al. | The Effect of Chinese Herbal Medicine Formula mKG on Allergic Asthma by Regulating Lung and Plasma Metabolic Alternations. | 2017 | Int J Mol Sci | pmid:28287417 |
| Notartomaso S et al. | Analgesia induced by the epigenetic drug, L-acetylcarnitine, outlasts the end of treatment in mouse models of chronic inflammatory and neuropathic pain. | 2017 | Mol Pain | pmid:28326943 |
| Lau T et al. | Stress-induced structural plasticity of medial amygdala stellate neurons and rapid prevention by a candidate antidepressant. | 2017 | Mol. Psychiatry | pmid:27240534 |
| Robinson BL et al. | Distinct effects of ketamine and acetyl L-carnitine on the dopamine system in zebrafish. | 2016 Mar-Apr | Neurotoxicol Teratol | pmid:26898327 |
| Fišar Z et al. | Effect of Simvastatin, Coenzyme Q10, Resveratrol, Acetylcysteine and Acetylcarnitine on Mitochondrial Respiration. | 2016 | Folia Biol. (Praha) | pmid:27187037 |
| Li S et al. | Effects of acetyl-L-carnitine and methylcobalamin for diabetic peripheral neuropathy: A multicenter, randomized, double-blind, controlled trial. | 2016 | J Diabetes Investig | pmid:27180954 |
| Huber K et al. | Metabotypes with properly functioning mitochondria and anti-inflammation predict extended productive life span in dairy cows. | 2016 | Sci Rep | pmid:27089826 |
| Curran MW et al. | Acetyl-L-carnitine (ALCAR) to enhance nerve regeneration in carpal tunnel syndrome: study protocol for a randomized, placebo-controlled trial. | 2016 | Trials | pmid:27079660 |
| Maldonado C et al. | Carnitine and/or Acetylcarnitine Deficiency as a Cause of Higher Levels of Ammonia. | 2016 | Biomed Res Int | pmid:26998483 |
| Lu Y et al. | Acetylcarnitine Is a Candidate Diagnostic and Prognostic Biomarker of Hepatocellular Carcinoma. | 2016 | Cancer Res. | pmid:26976432 |
| Diekman EF et al. | Altered Energetics of Exercise Explain Risk of Rhabdomyolysis in Very Long-Chain Acyl-CoA Dehydrogenase Deficiency. | 2016 | PLoS ONE | pmid:26881790 |
| Katoh T et al. | [Application of Metabolomics to Multiple Chemical Sensitivity Research]. | 2016 | Nihon Eiseigaku Zasshi | pmid:26832623 |
| Li X et al. | An acetyl-L-carnitine switch on mitochondrial dysfunction and rescue in the metabolomics study on aluminum oxide nanoparticles. | 2016 | Part Fibre Toxicol | pmid:26772537 |
| Pochini L et al. | Acetylcholine and acetylcarnitine transport in peritoneum: Role of the SLC22A4 (OCTN1) transporter. | 2016 | Biochim. Biophys. Acta | pmid:26724204 |
| Ewan EE and Hagg T | Intrathecal Acetyl-L-Carnitine Protects Tissue and Improves Function after a Mild Contusive Spinal Cord Injury in Rats. | 2016 | J. Neurotrauma | pmid:26415041 |
| Dundar HA et al. | Protective Effect of Acetyl-L-Carnitine Against Doxorubicin-induced Cardiotoxicity in Wistar Albino Rats. | 2016 | Arch. Med. Res. | pmid:28262191 |
| Flori A et al. | Real-time cardiac metabolism assessed with hyperpolarized [1-(13) C]acetate in a large-animal model. | 2015 May-Jun | Contrast Media Mol Imaging | pmid:25201079 |
| Li S and Laher I | Exercise Pills: At the Starting Line. | 2015 | Trends Pharmacol. Sci. | pmid:26439443 |
| Huemer M et al. | Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines. | 2015 | J. Inherit. Metab. Dis. | pmid:25762406 |
| Schooneman MG et al. | Transorgan fluxes in a porcine model reveal a central role for liver in acylcarnitine metabolism. | 2015 | Am. J. Physiol. Endocrinol. Metab. | pmid:26037250 |
| Sarkar S et al. | Histopathological and electrophysiological indices of rotenone-evoked dopaminergic toxicity: Neuroprotective effects of acetyl-L-carnitine. | 2015 | Neurosci. Lett. | pmid:26321151 |
| Lindsay KL et al. | Longitudinal Metabolomic Profiling of Amino Acids and Lipids across Healthy Pregnancy. | 2015 | PLoS ONE | pmid:26716698 |
| Robinson BL et al. | Opposing effects of ketamine and acetyl L-carnitine on the serotonergic system of zebrafish. | 2015 | Neurosci. Lett. | pmid:26365406 |
| Samms RJ et al. | Dual effects of fibroblast growth factor 21 on hepatic energy metabolism. | 2015 | J. Endocrinol. | pmid:26294388 |
| De Luca A et al. | Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells. | 2015 | Oncotarget | pmid:26087310 |
| Macconi D et al. | Sirtuin3 Dysfunction Is the Key Determinant of Skeletal Muscle Insulin Resistance by Angiotensin II. | 2015 | PLoS ONE | pmid:25993470 |
| Li S et al. | Acetyl-L-carnitine in the treatment of peripheral neuropathic pain: a systematic review and meta-analysis of randomized controlled trials. | 2015 | PLoS ONE | pmid:25751285 |
| Kerner J et al. | Acetyl-L-carnitine increases mitochondrial protein acetylation in the aged rat heart. | 2015 | Mech. Ageing Dev. | pmid:25660059 |
| Morigi M et al. | Sirtuin 3-dependent mitochondrial dynamic improvements protect against acute kidney injury. | 2015 | J. Clin. Invest. | pmid:25607838 |
| Xu S et al. | In vivo longitudinal proton magnetic resonance spectroscopy on neonatal hypoxic-ischemic rat brain injury: Neuroprotective effects of acetyl-L-carnitine. | 2015 | Magn Reson Med | pmid:25461739 |
| Wu J et al. | TGF-β1 induces senescence of bone marrow mesenchymal stem cells via increase of mitochondrial ROS production. | 2014 | BMC Dev. Biol. | pmid:24886313 |
| Mehrotra A and Sandhir R | Mitochondrial cofactors in experimental Huntington's disease: behavioral, biochemical and histological evaluation. | 2014 | Behav. Brain Res. | pmid:24393741 |
| Phillipson OT | Management of the aging risk factor for Parkinson's disease. | 2014 | Neurobiol. Aging | pmid:24246717 |
| Liu J et al. | Reloading functionally ameliorates disuse-induced muscle atrophy by reversing mitochondrial dysfunction, and similar benefits are gained by administering a combination of mitochondrial nutrients. | 2014 | Free Radic. Biol. Med. | pmid:24418157 |
| Farahpour MR and Ghayour SJ | Effect of in situ delivery of acetyl-L-carnitine on peripheral nerve regeneration and functional recovery in transected sciatic nerve in rat. | 2014 | Int J Surg | pmid:25448663 |
| Lindeboom L et al. | Long-echo time MR spectroscopy for skeletal muscle acetylcarnitine detection. | 2014 | J. Clin. Invest. | pmid:25271624 |
| Dodd MS et al. | Impaired in vivo mitochondrial Krebs cycle activity after myocardial infarction assessed using hyperpolarized magnetic resonance spectroscopy. | 2014 | Circ Cardiovasc Imaging | pmid:25201905 |
| Callander N et al. | Acetyl-L-carnitine (ALCAR) for the prevention of chemotherapy-induced peripheral neuropathy in patients with relapsed or refractory multiple myeloma treated with bortezomib, doxorubicin and low-dose dexamethasone: a study from the Wisconsin Oncology Network. | 2014 | Cancer Chemother. Pharmacol. | pmid:25168296 |
| Bigford GE and Del Rossi G | Supplemental substances derived from foods as adjunctive therapeutic agents for treatment of neurodegenerative diseases and disorders. | 2014 | Adv Nutr | pmid:25022989 |
| Furuichi Y et al. | Imaging mass spectrometry reveals fiber-specific distribution of acetylcarnitine and contraction-induced carnitine dynamics in rat skeletal muscles. | 2014 | Biochim. Biophys. Acta | pmid:24882639 |
| Josan S et al. | Dynamic metabolic imaging of hyperpolarized [2-(13) C]pyruvate using spiral chemical shift imaging with alternating spectral band excitation. | 2014 | Magn Reson Med | pmid:23878057 |
| Jiang Q et al. | Oral acetyl-L-carnitine treatment in hepatic encephalopathy: view of evidence-based medicine. | 2013 Sep-Oct | Ann Hepatol | pmid:24018499 |
| Cuevas E et al. | Acetyl L-carnitine protects motor neurons and Rohon-Beard sensory neurons against ketamine-induced neurotoxicity in zebrafish embryos. | 2013 Sep-Oct | Neurotoxicol Teratol | pmid:23896048 |
| Laird MD et al. | Augmentation of normal and glutamate-impaired neuronal respiratory capacity by exogenous alternative biofuels. | 2013 | Transl Stroke Res | pmid:24323418 |
| Kathirvel E et al. | Acetyl-L-carnitine and lipoic acid improve mitochondrial abnormalities and serum levels of liver enzymes in a mouse model of nonalcoholic fatty liver disease. | 2013 | Nutr Res | pmid:24176233 |
| Rajguru R | Military aircrew and noise-induced hearing loss: prevention and management. | 2013 | Aviat Space Environ Med | pmid:24459798 |
| Burotto M and Fojo AT | Acetyl-L-carnitine and prevention of chemotherapy-induced peripheral neuropathy: can anything work? | 2013 | Oncologist | pmid:24217999 |
| Campone M et al. | A double-blind, randomized phase II study to evaluate the safety and efficacy of acetyl-L-carnitine in the prevention of sagopilone-induced peripheral neuropathy. | 2013 | Oncologist | pmid:24105751 |
| Ren J et al. | Dynamic monitoring of carnitine and acetylcarnitine in the trimethylamine signal after exercise in human skeletal muscle by 7T 1H-MRS. | 2013 | Magn Reson Med | pmid:22473634 |