Acetyl-d-carnitine

Acetyl-d-carnitine is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2875 references associated with Acetyl-d-carnitine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Acetyl-d-carnitine

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Acetyl-d-carnitine

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amino Acid Metabolism, Inborn Errors D000592 16 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Parkinson Disease D010300 53 associated lipids
Cleft Lip D002971 8 associated lipids
Proteostasis Deficiencies D057165 5 associated lipids
Total 7

All references with Acetyl-d-carnitine

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Authors Title Published Journal PubMed Link
Hershman DL et al. Randomized double-blind placebo-controlled trial of acetyl-L-carnitine for the prevention of taxane-induced neuropathy in women undergoing adjuvant breast cancer therapy. 2013 J. Clin. Oncol. pmid:23733756
pmid:23740559
pmid:23746372
pmid:23774646
pmid:23806723
Ruggiero FM et al. Effect of aging and acetyl-L-carnitine on the lipid composition of rat plasma and erythrocytes. 1990 Biochem. Biophys. Res. Commun. pmid:2383260
pmid:2385653
Renstrom B et al. Mechanisms of substrate preference for oxidative metabolism during early myocardial reperfusion. 1990 Am. J. Physiol. pmid:2386216
Pekkinen J et al. Betaine supplementation causes increase in carnitine metabolites in the muscle and liver of mice fed a high-fat diet as studied by nontargeted LC-MS metabolomics approach. 2013 Mol Nutr Food Res pmid:23868375
Babicová A et al. In vivo study of radioprotective effect of NO-synthase inhibitors and acetyl-L-carnitine. 2013 Physiol Res pmid:23869893
pmid:23877176
Josan S et al. Dynamic metabolic imaging of hyperpolarized [2-(13) C]pyruvate using spiral chemical shift imaging with alternating spectral band excitation. 2014 Magn Reson Med pmid:23878057
Cuevas E et al. Acetyl L-carnitine protects motor neurons and Rohon-Beard sensory neurons against ketamine-induced neurotoxicity in zebrafish embryos. 2013 Sep-Oct Neurotoxicol Teratol pmid:23896048
pmid:2390292
pmid:23906768
Wang CH et al. Acetyl-l-carnitine and oxfenicine on cardiac pumping mechanics in streptozotocin-induced diabetes in male Wistar rats. 2013 PLoS ONE pmid:23922880
pmid:2394661
Brennan BP et al. A placebo-controlled trial of acetyl-L-carnitine and α-lipoic acid in the treatment of bipolar depression. 2013 J Clin Psychopharmacol pmid:23948785
pmid:23965166
Morand R et al. Quantification of plasma carnitine and acylcarnitines by high-performance liquid chromatography-tandem mass spectrometry using online solid-phase extraction. 2013 Anal Bioanal Chem pmid:23995505
pmid:24012657
Jiang Q et al. Oral acetyl-L-carnitine treatment in hepatic encephalopathy: view of evidence-based medicine. 2013 Sep-Oct Ann Hepatol pmid:24018499
Campone M et al. A double-blind, randomized phase II study to evaluate the safety and efficacy of acetyl-L-carnitine in the prevention of sagopilone-induced peripheral neuropathy. 2013 Oncologist pmid:24105751
Kathirvel E et al. Acetyl-L-carnitine and lipoic acid improve mitochondrial abnormalities and serum levels of liver enzymes in a mouse model of nonalcoholic fatty liver disease. 2013 Nutr Res pmid:24176233
Burotto M and Fojo AT Acetyl-L-carnitine and prevention of chemotherapy-induced peripheral neuropathy: can anything work? 2013 Oncologist pmid:24217999
Phillipson OT Management of the aging risk factor for Parkinson's disease. 2014 Neurobiol. Aging pmid:24246717
pmid:24286513
pmid:24321164
Laird MD et al. Augmentation of normal and glutamate-impaired neuronal respiratory capacity by exogenous alternative biofuels. 2013 Transl Stroke Res pmid:24323418
Pocchiari M et al. Amphotericin B delays the incubation period of scrapie in intracerebrally inoculated hamsters. 1987 J. Gen. Virol. pmid:2433387
pmid:24337254
Bales JR et al. 1H NMR studies of urine during fasting: excretion of ketone bodies and acetylcarnitine. 1986 Magn Reson Med pmid:2434822
Mehrotra A and Sandhir R Mitochondrial cofactors in experimental Huntington's disease: behavioral, biochemical and histological evaluation. 2014 Behav. Brain Res. pmid:24393741
Liu J et al. Reloading functionally ameliorates disuse-induced muscle atrophy by reversing mitochondrial dysfunction, and similar benefits are gained by administering a combination of mitochondrial nutrients. 2014 Free Radic. Biol. Med. pmid:24418157
Rajguru R Military aircrew and noise-induced hearing loss: prevention and management. 2013 Aviat Space Environ Med pmid:24459798
Wojtecka-Lukasik E et al. Anti-inflammatory drugs modulate histamine release from mast cells induced by fibrinogen degradation products. 1988 Ann. Rheum. Dis. pmid:2452608
pmid:24530554
pmid:24607292
pmid:24680856
pmid:24704513
pmid:24704589
pmid:2474331
pmid:24786526
Furuichi Y et al. Imaging mass spectrometry reveals fiber-specific distribution of acetylcarnitine and contraction-induced carnitine dynamics in rat skeletal muscles. 2014 Biochim. Biophys. Acta pmid:24882639
Wu J et al. TGF-β1 induces senescence of bone marrow mesenchymal stem cells via increase of mitochondrial ROS production. 2014 BMC Dev. Biol. pmid:24886313
pmid:24923488
Bigford GE and Del Rossi G Supplemental substances derived from foods as adjunctive therapeutic agents for treatment of neurodegenerative diseases and disorders. 2014 Adv Nutr pmid:25022989
Fernández Ortega MF Effect of dietary lysine level and protein restriction on the lipids and carnitine levels in the liver of pregnant rats. 1989 Ann. Nutr. Metab. pmid:2508533
Callander N et al. Acetyl-L-carnitine (ALCAR) for the prevention of chemotherapy-induced peripheral neuropathy in patients with relapsed or refractory multiple myeloma treated with bortezomib, doxorubicin and low-dose dexamethasone: a study from the Wisconsin Oncology Network. 2014 Cancer Chemother. Pharmacol. pmid:25168296
Flori A et al. Real-time cardiac metabolism assessed with hyperpolarized [1-(13) C]acetate in a large-animal model. 2015 May-Jun Contrast Media Mol Imaging pmid:25201079

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