Acetyl-d-carnitine

Acetyl-d-carnitine is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 2875 references associated with Acetyl-d-carnitine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Acetyl-d-carnitine

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Acetyl-d-carnitine

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amino Acid Metabolism, Inborn Errors D000592 16 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Parkinson Disease D010300 53 associated lipids
Cleft Lip D002971 8 associated lipids
Proteostasis Deficiencies D057165 5 associated lipids
Total 7

All references with Acetyl-d-carnitine

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Authors Title Published Journal PubMed Link
Abdul Muneer PM et al. Inhibitory effects of alcohol on glucose transport across the blood-brain barrier leads to neurodegeneration: preventive role of acetyl-L: -carnitine. 2011 Psychopharmacology (Berl.) pmid:21079922
Boss A et al. Noninvasive assessment of exercise-related intramyocellular acetylcarnitine in euglycemia and hyperglycemia in patients with type 1 diabetes using ¹H magnetic resonance spectroscopy: a randomized single-blind crossover study. 2011 Diabetes Care pmid:20978101
Ponte F et al. Protective effect of acetyl-l-carnitine and α-lipoic acid against the acute toxicity of diepoxybutane to human lymphocytes. 2011 Toxicology pmid:21807063
Ames BN Optimal micronutrients delay mitochondrial decay and age-associated diseases. 2010 Jul-Aug Mech. Ageing Dev. pmid:20420847
Cherry CL et al. Ubisol-Aqua: coenzyme Q10 prevents antiretroviral toxic neuropathy in an in vitro model. 2010 Curr. HIV Res. pmid:20158454
Fiehn O et al. Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women. 2010 PLoS ONE pmid:21170321
Cheng KH et al. Newborn screening for methylmalonic aciduria by tandem mass spectrometry: 7 years' experience from two centers in Taiwan. 2010 J Chin Med Assoc pmid:20603089
Binienda ZK et al. Assessment of 3-nitropropionic acid-evoked peripheral neuropathy in rats: neuroprotective effects of acetyl-l-carnitine and resveratrol. 2010 Neurosci. Lett. pmid:20542088
Zhang H et al. Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease. 2010 J. Cell. Mol. Med. pmid:20414966
Milazzo L et al. Effect of antioxidants on mitochondrial function in HIV-1-related lipoatrophy: a pilot study. 2010 AIDS Res. Hum. Retroviruses pmid:20977356
Kopsky DJ and Hesselink JM Nerve regeneration in neuropathic pain. 2010 Pain Med pmid:21199307
Rump TJ et al. Acetyl-L-carnitine protects neuronal function from alcohol-induced oxidative damage in the brain. 2010 Free Radic. Biol. Med. pmid:20708681
Kuritzky L Managing diabetic peripheral neuropathic pain in primary care. 2010 J Fam Pract pmid:20544053
Calabrese V et al. Redox homeostasis and cellular stress response in aging and neurodegeneration. 2010 Methods Mol. Biol. pmid:20013185
Scafidi S et al. Neuroprotection by acetyl-L-carnitine after traumatic injury to the immature rat brain. 2010 Dev. Neurosci. pmid:21228558
Lancaster CS et al. Cisplatin-induced downregulation of OCTN2 affects carnitine wasting. 2010 Clin. Cancer Res. pmid:20858838
Pisano C et al. Metabolic approach to the enhancement of antitumor effect of chemotherapy: a key role of acetyl-L-carnitine. 2010 Clin. Cancer Res. pmid:20562210
Hozyasz KK et al. Malonylcarnitine in newborns with non-syndromic cleft lip with or without cleft palate. 2010 Int J Oral Sci pmid:21125791
Palermo V et al. Acetyl-L-carnitine protects yeast cells from apoptosis and aging and inhibits mitochondrial fission. 2010 Aging Cell pmid:20550520
Hori T et al. Carnitine palmitoyltransferase 2 deficiency: the time-course of blood and urinary acylcarnitine levels during initial L-carnitine supplementation. 2010 Tohoku J. Exp. Med. pmid:20543534
Scafidi S et al. Metabolism of acetyl-L-carnitine for energy and neurotransmitter synthesis in the immature rat brain. 2010 J. Neurochem. pmid:20477950
Ruggenenti P et al. Oral acetyl-L-carnitine therapy and insulin resistance. 2010 Hypertension pmid:20439816
Patel SP et al. Acetyl-L-carnitine ameliorates mitochondrial dysfunction following contusion spinal cord injury. 2010 J. Neurochem. pmid:20438613
Acetyl-L-carnitine. Monograph. 2010 Altern Med Rev pmid:20359271
Hellstrom WJ Medical management of Peyronie's disease. 2009 Jul-Aug J. Androl. pmid:18974422
Elanchezhian R et al. Evaluation of lenticular antioxidant and redox system components in the lenses of acetyl-L-carnitine treatment in BSO-induced glutathione deprivation. 2009 Mol. Vis. pmid:19649174
Waller AP et al. Oral acetate supplementation after prolonged moderate intensity exercise enhances early muscle glycogen resynthesis in horses. 2009 Exp. Physiol. pmid:19429643
Suchy J et al. Dietary supplementation with a combination of alpha-lipoic acid, acetyl-L-carnitine, glycerophosphocoline, docosahexaenoic acid, and phosphatidylserine reduces oxidative damage to murine brain and improves cognitive performance. 2009 Nutr Res pmid:19185780
Engle DB et al. Effect of acetyl-l-carnitine on ovarian cancer cells' proliferation, nerve growth factor receptor (Trk-A and p75) expression, and the cytotoxic potential of paclitaxel and carboplatin. 2009 Gynecol. Oncol. pmid:19263582
Aliev G et al. Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats. 2009 J. Cell. Mol. Med. pmid:18373733
Long J et al. Mitochondrial decay in the brains of old rats: ameliorating effect of alpha-lipoic acid and acetyl-L-carnitine. 2009 Neurochem. Res. pmid:18846423
Shenk JC et al. The effect of acetyl-L-carnitine and R-alpha-lipoic acid treatment in ApoE4 mouse as a model of human Alzheimer's disease. 2009 J. Neurol. Sci. pmid:19342064
Christie LA et al. Short-term supplementation with acetyl-L-carnitine and lipoic acid alters plasma protein carbonyl levels but does not improve cognition in aged beagles. 2009 Exp. Gerontol. pmid:19735717
Hall SS Treatments for fragile X syndrome: a closer look at the data. 2009 Dev Disabil Res Rev pmid:20014373
Jensen PR et al. Tissue-specific short chain fatty acid metabolism and slow metabolic recovery after ischemia from hyperpolarized NMR in vivo. 2009 J. Biol. Chem. pmid:19861411
Rueda JR et al. Systematic review of pharmacological treatments in fragile X syndrome. 2009 BMC Neurol pmid:19822023
Rosca MG et al. Mitochondria in the elderly: Is acetylcarnitine a rejuvenator? 2009 Adv. Drug Deliv. Rev. pmid:19720100
Whaley-Connell A and Sowers JR Hypertension and insulin resistance. 2009 Hypertension pmid:19635987
Ruggenenti P et al. Ameliorating hypertension and insulin resistance in subjects at increased cardiovascular risk: effects of acetyl-L-carnitine therapy. 2009 Hypertension pmid:19620516
Arafa HM et al. Acetyl-L-carnitine ameliorates caerulein-induced acute pancreatitis in rats. 2009 Basic Clin. Pharmacol. Toxicol. pmid:19371263
Schroeder MA et al. Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy. 2009 FASEB J. pmid:19329759
Musicco C et al. Accumulation of overoxidized Peroxiredoxin III in aged rat liver mitochondria. 2009 Biochim. Biophys. Acta pmid:19272351
Valcour V et al. Acetyl-l-carnitine and nucleoside reverse transcriptase inhibitor-associated neuropathy in HIV infection. 2009 HIV Med. pmid:19200173
Vollaard NB et al. Systematic analysis of adaptations in aerobic capacity and submaximal energy metabolism provides a unique insight into determinants of human aerobic performance. 2009 J. Appl. Physiol. pmid:19196912
Zhang Z et al. Acetyl-l-carnitine inhibits TNF-alpha-induced insulin resistance via AMPK pathway in rat skeletal muscle cells. 2009 FEBS Lett. pmid:19121314
Soczynska JK et al. Acetyl-L-carnitine and alpha-lipoic acid: possible neurotherapeutic agents for mood disorders? 2008 Expert Opin Investig Drugs pmid:18491985
Shen W et al. R-alpha-lipoic acid and acetyl-L-carnitine complementarily promote mitochondrial biogenesis in murine 3T3-L1 adipocytes. 2008 Diabetologia pmid:18026715
Wolf S et al. Chemotherapy-induced peripheral neuropathy: prevention and treatment strategies. 2008 Eur. J. Cancer pmid:18571399
Shen W et al. Protective effects of R-alpha-lipoic acid and acetyl-L-carnitine in MIN6 and isolated rat islet cells chronically exposed to oleic acid. 2008 J. Cell. Biochem. pmid:18260126
Lal A et al. Lipoic acid and acetyl-carnitine reverse iron-induced oxidative stress in human fibroblasts. 2008 Redox Rep. pmid:18284845

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