Acetyl-d-carnitine is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Acetyl-d-carnitine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Amino Acid Metabolism, Inborn Errors | D000592 | 16 associated lipids |
| Coronary Artery Disease | D003324 | 47 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Cleft Lip | D002971 | 8 associated lipids |
| Proteostasis Deficiencies | D057165 | 5 associated lipids |
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Leblanc PJ et al. | Effects of 7 wk of endurance training on human skeletal muscle metabolism during submaximal exercise. | 2004 | J. Appl. Physiol. | pmid:15220302 |
| Tanaka Y et al. | Acetyl-L-carnitine supplementation restores decreased tissue carnitine levels and impaired lipid metabolism in aged rats. | 2004 | J. Lipid Res. | pmid:14703509 |
| Ames BN and Liu J | Delaying the mitochondrial decay of aging with acetylcarnitine. | 2004 | Ann. N. Y. Acad. Sci. | pmid:15591008 |
| Bastianetto S and Quirion R | Natural antioxidants and neurodegenerative diseases. | 2004 | Front. Biosci. | pmid:15353369 |
| Ames BN | Delaying the mitochondrial decay of aging. | 2004 | Ann. N. Y. Acad. Sci. | pmid:15247055 |
| Feher J et al. | Mitotropic compounds for the treatment of age-related macular degeneration. The metabolic approach and a pilot study. | 2003 Sep-Oct | Ophthalmologica | pmid:12913326 |
| Defani MA et al. | Effect of acetyl-L-carnitine on VIP-ergic neurons in the jejunum submucous plexus of diabetic rats. | 2003 | Arq Neuropsiquiatr | pmid:14762599 |
| Pisano C et al. | Paclitaxel and Cisplatin-induced neurotoxicity: a protective role of acetyl-L-carnitine. | 2003 | Clin. Cancer Res. | pmid:14654561 |
| Pascale E et al. | Modulation of methylation in the FMR1 promoter region after long term treatment with L-carnitine and acetyl-L-carnitine. | 2003 | J. Med. Genet. | pmid:12807975 |
| Masi F et al. | Effects of long-term acetyl-L-carnitine administration in rats--II: Protection against the disrupting effect of stress on the acquisition of appetitive behavior. | 2003 | Neuropsychopharmacology | pmid:12655313 |
| Mattei B et al. | Pharmacologically induced enhancement of recurrent inhibition in humans: effects on motoneurone discharge patterns. | 2003 | J. Physiol. (Lond.) | pmid:12611926 |
| Arafa HM and Sayed-Ahmed MM | Protective role of carnitine esters against alcohol-induced gastric lesions in rats. | 2003 | Pharmacol. Res. | pmid:12860448 |
| Cui J et al. | Effects of L-carnitine and its derivatives on postischemic cardiac function, ventricular fibrillation and necrotic and apoptotic cardiomyocyte death in isolated rat hearts. | 2003 | Mol. Cell. Biochem. | pmid:14674702 |
| Beal MF | Bioenergetic approaches for neuroprotection in Parkinson's disease. | 2003 | Ann. Neurol. | pmid:12666097 |
| Ori C et al. | Effects of acetyl-L-carnitine on regional cerebral glucose metabolism in awake rats. | 2002 | Brain Res. | pmid:12270513 |
| Sharman EH et al. | Reversal of biochemical and behavioral parameters of brain aging by melatonin and acetyl L-carnitine. | 2002 | Brain Res. | pmid:12445964 |
| Roberts PA et al. | The temporal relationship between glycogen phosphorylase and activation of the pyruvate dehydrogenase complex during adrenaline infusion in resting canine skeletal muscle. | 2002 | J. Physiol. (Lond.) | pmid:12433969 |
| Tolu P et al. | Effects of long-term acetyl-L-carnitine administration in rats: I. increased dopamine output in mesocorticolimbic areas and protection toward acute stress exposure. | 2002 | Neuropsychopharmacology | pmid:12225698 |
| Pop-Busui R et al. | Dissection of metabolic, vascular, and nerve conduction interrelationships in experimental diabetic neuropathy by cyclooxygenase inhibition and acetyl-L-carnitine administration. | 2002 | Diabetes | pmid:12145179 |
| Graziano F et al. | Potential role of levocarnitine supplementation for the treatment of chemotherapy-induced fatigue in non-anaemic cancer patients. | 2002 | Br. J. Cancer | pmid:12085175 |
| Chiechio S et al. | L-Acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors. | 2002 | Mol. Pharmacol. | pmid:11961116 |
| Iossa S et al. | Acetyl-L-carnitine supplementation differently influences nutrient partitioning, serum leptin concentration and skeletal muscle mitochondrial respiration in young and old rats. | 2002 | J. Nutr. | pmid:11925454 |
| Fisher JS et al. | Activation of AMP kinase enhances sensitivity of muscle glucose transport to insulin. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:11739078 |
| Liu J et al. | Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites. | 2002 | Ann. N. Y. Acad. Sci. | pmid:11976193 |
| Hagen TM et al. | Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid. | 2002 | Ann. N. Y. Acad. Sci. | pmid:11976222 |
| Watt MJ et al. | Carbohydrate ingestion reduces skeletal muscle acetylcarnitine availability but has no effect on substrate phosphorylation at the onset of exercise in man. | 2002 | J. Physiol. (Lond.) | pmid:12411537 |
| Watt MJ et al. | Intramuscular triacylglycerol, glycogen and acetyl group metabolism during 4 h of moderate exercise in man. | 2002 | J. Physiol. (Lond.) | pmid:12068055 |
| Tyni T et al. | Analysis of mitochondrial fatty acid oxidation intermediates by tandem mass spectrometry from intact mitochondria prepared from homogenates of cultured fibroblasts, skeletal muscle cells, and fresh muscle. | 2002 | Pediatr. Res. | pmid:12084849 |
| Hagen TM et al. | Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11854487 |
| Liu J et al. | Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11854488 |
| Grassi B et al. | Oxygen uptake on-kinetics in dog gastrocnemius in situ following activation of pyruvate dehydrogenase by dichloroacetate. | 2002 | J. Physiol. (Lond.) | pmid:11773328 |
| Liu J et al. | Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11854529 |
| Calvani M et al. | [L-acetylcarnitine treatment on fragile X patients hyperactive behaviour]. | 2001 | Rev Neurol | pmid:12447823 |
| Tomita K et al. | Enzymatic determination of acetylcarnitine for diagnostic applications. | 2001 | J Pharm Biomed Anal | pmid:11248512 |
| Kido Y et al. | Functional relevance of carnitine transporter OCTN2 to brain distribution of L-carnitine and acetyl-L-carnitine across the blood-brain barrier. | 2001 | J. Neurochem. | pmid:11739607 |
| van Loon LJ et al. | The effects of increasing exercise intensity on muscle fuel utilisation in humans. | 2001 | J. Physiol. (Lond.) | pmid:11579177 |
| Biagiotti G and Cavallini G | Acetyl-L-carnitine vs tamoxifen in the oral therapy of Peyronie's disease: a preliminary report. | 2001 | BJU Int. | pmid:11446848 |
| Benzerrouk R and Qureshi IA | Hepatic mitochondrial proteins in congenitally hyperammonemic spf mice: effect of acetyl-L-carnitine. | 2001 | Biosci. Biotechnol. Biochem. | pmid:11330659 |
| Parr TB | A new technique to elevate night time growth hormone release and a potential growth hormone feedback control loop. | 2001 | Med. Hypotheses | pmid:11388776 |
| Evans MK et al. | Effects of acetate infusion and hyperoxia on muscle substrate phosphorylation after onset of moderate exercise. | 2001 | Am. J. Physiol. Endocrinol. Metab. | pmid:11701427 |
| Kottlors M et al. | Valproic acid triggers acute rhabdomyolysis in a patient with carnitine palmitoyltransferase type II deficiency. | 2001 | Neuromuscul. Disord. | pmid:11595519 |
| Ishii T et al. | Anti-apoptotic effect of acetyl-l-carnitine and I-carnitine in primary cultured neurons. | 2000 | Jpn. J. Pharmacol. | pmid:10928324 |
| Jones AR and Bubb WA | Substrates for endogenous metabolism by mature boar spermatozoa. | 2000 | J. Reprod. Fertil. | pmid:10864822 |
| Stevens RD et al. | Assay for free and total carnitine in human plasma using tandem mass spectrometry. | 2000 | Clin. Chem. | pmid:10794762 |
| Bayles DO and Wilkinson BJ | Osmoprotectants and cryoprotectants for Listeria monocytogenes. | 2000 | Lett. Appl. Microbiol. | pmid:10728555 |
| Mroczkowska JE et al. | Blood-brain barrier controls carnitine level in the brain: a study on a model system with RBE4 cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10623637 |
| Pace S et al. | Pharmacokinetics of propionyl-L-carnitine in humans: evidence for saturable tubular reabsorption. | 2000 | Br J Clin Pharmacol | pmid:11069438 |
| Mancinelli A et al. | Disposition of L-carnitine and its short-chain esters, acetyl-L-carnitine and propionyl-L-carnitine, in the rat isolated perfused liver. | 2000 | Drug Metab. Dispos. | pmid:11095575 |
| Seidman MD et al. | Biologic activity of mitochondrial metabolites on aging and age-related hearing loss. | 2000 | Am J Otol | pmid:10733178 |
| St Amand TA et al. | Pyruvate overrides inhibition of PDH during exercise after a low-carbohydrate diet. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:10913026 |