Acetyl-l-carnitine

Acetyl-l-carnitine is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2904 references associated with Acetyl-l-carnitine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for Acetyl-l-carnitine

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Acetyl-l-carnitine

MeSH term MeSH ID Detail
Proteostasis Deficiencies D057165 5 associated lipids
Cleft Lip D002971 8 associated lipids
Amino Acid Metabolism, Inborn Errors D000592 16 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Parkinson Disease D010300 53 associated lipids
Alzheimer Disease D000544 76 associated lipids
Body Weight D001835 333 associated lipids
Total 7

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Acetyl-l-carnitine

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Authors Title Published Journal PubMed Link
Zaitone SA et al. Acetyl-L-carnitine and α-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy. 2012 Pharmacol. Biochem. Behav. pmid:21958946
Muoio DM et al. Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility. 2012 Cell Metab. pmid:22560225
Balschi JA In vivo clinical measures of intermediary metabolism are inadequate: can a new magnetic resonance spectroscopy technology do better? 2012 Circ Cardiovasc Imaging pmid:22438422
Schroeder MA et al. The cycling of acetyl-coenzyme A through acetylcarnitine buffers cardiac substrate supply: a hyperpolarized 13C magnetic resonance study. 2012 Circ Cardiovasc Imaging pmid:22238215
Karalija A et al. Neuroprotective effects of N-acetyl-cysteine and acetyl-L-carnitine after spinal cord injury in adult rats. 2012 PLoS ONE pmid:22815926
Sharma S et al. Preserving mitochondrial function prevents the proteasomal degradation of GTP cyclohydrolase I. 2012 Free Radic. Biol. Med. pmid:22583703
Patel SP et al. Acetyl-L-carnitine treatment following spinal cord injury improves mitochondrial function correlated with remarkable tissue sparing and functional recovery. 2012 Neuroscience pmid:22445934
Zhang R et al. Neuroprotective effects of pre-treatment with l-carnitine and acetyl-L-carnitine on ischemic injury in vivo and in vitro. 2012 Int J Mol Sci pmid:22408439
Hu C et al. Inhibition of OCTN2-mediated transport of carnitine by etoposide. 2012 Mol. Cancer Ther. pmid:22389472
Wu R et al. Metabolomic analysis reveals that carnitines are key regulatory metabolites in phase transition of the locusts. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22328148
Boss A et al. Skeletal muscle ¹H MRSI before and after prolonged exercise. II. visibility of free carnitine. 2012 Magn Reson Med pmid:22287218
Mingorance C et al. Critical update for the clinical use of L-carnitine analogs in cardiometabolic disorders. 2011 Vasc Health Risk Manag pmid:21490942
Haorah J et al. Stabilization of superoxide dismutase by acetyl-l-carnitine in human brain endothelium during alcohol exposure: novel protective approach. 2011 Free Radic. Biol. Med. pmid:21782933
Jiang X et al. Acetyl-L-carnitine ameliorates spatial memory deficits induced by inhibition of phosphoinositol-3 kinase and protein kinase C. 2011 J. Neurochem. pmid:21689104
Abdul Muneer PM et al. Methamphetamine inhibits the glucose uptake by human neurons and astrocytes: stabilization by acetyl-L-carnitine. 2011 PLoS ONE pmid:21556365
Cacicedo JM et al. Activation of AMP-activated protein kinase prevents lipotoxicity in retinal pericytes. 2011 Invest. Ophthalmol. Vis. Sci. pmid:21345991
Malaguarnera M et al. Oral acetyl-L-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. 2011 Am. J. Clin. Nutr. pmid:21310833
O'Sullivan A et al. Dietary intake patterns are reflected in metabolomic profiles: potential role in dietary assessment studies. 2011 Am. J. Clin. Nutr. pmid:21177801
Abdul Muneer PM et al. Inhibitory effects of alcohol on glucose transport across the blood-brain barrier leads to neurodegeneration: preventive role of acetyl-L: -carnitine. 2011 Psychopharmacology (Berl.) pmid:21079922
Boss A et al. Noninvasive assessment of exercise-related intramyocellular acetylcarnitine in euglycemia and hyperglycemia in patients with type 1 diabetes using ¹H magnetic resonance spectroscopy: a randomized single-blind crossover study. 2011 Diabetes Care pmid:20978101