Acetyl-l-carnitine is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Acetyl-l-carnitine
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Amino Acid Metabolism, Inborn Errors | D000592 | 16 associated lipids |
| Coronary Artery Disease | D003324 | 47 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Cleft Lip | D002971 | 8 associated lipids |
| Proteostasis Deficiencies | D057165 | 5 associated lipids |
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
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| pmid:10087170 | ||||
| pmid:10211764 | ||||
| pmid:10219976 | ||||
| pmid:10344589 | ||||
| pmid:10375455 | ||||
| Kidd PM | A review of nutrients and botanicals in the integrative management of cognitive dysfunction. | 1999 | Altern Med Rev | pmid:10383479 |
| pmid:10413658 | ||||
| Aureli T et al. | Entry of [(1,2-13C2)acetyl]-L-carnitine in liver tricarboxylic acid cycle and lipogenesis: a study by 13C NMR spectroscopy in conscious, freely moving rats. | 1999 | Eur. J. Biochem. | pmid:10429215 |
| Paradies G et al. | The effect of aging and acetyl-L-carnitine on the pyruvate transport and oxidation in rat heart mitochondria. | 1999 | FEBS Lett. | pmid:10431808 |
| Wu X et al. | Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10454528 |
| pmid:10536831 | ||||
| Howlett RA et al. | Skeletal muscle metabolism during high-intensity sprint exercise is unaffected by dichloroacetate or acetate infusion. | 1999 | J. Appl. Physiol. | pmid:10562618 |
| Parolin ML et al. | Regulation of skeletal muscle glycogen phosphorylase and PDH during maximal intermittent exercise. | 1999 | Am. J. Physiol. | pmid:10567017 |
| Löster H et al. | Effects of L-carnitine and its acetyl and propionyl esters on ATP and PCr levels of isolated rat hearts perfused without fatty acids and investigated by means of 31P-NMR spectroscopy. | 1999 | Mol. Cell. Biochem. | pmid:10569188 |
| pmid:10572901 | ||||
| pmid:10588848 | ||||
| Acetyl-L-carnitine. | 1999 | Altern Med Rev | pmid:10608918 | |
| Palmieri L et al. | Identification of the mitochondrial carnitine carrier in Saccharomyces cerevisiae. | 1999 | FEBS Lett. | pmid:10622748 |
| Mroczkowska JE et al. | Blood-brain barrier controls carnitine level in the brain: a study on a model system with RBE4 cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10623637 |
| Ganapathy ME et al. | beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter. | 2000 | J. Biol. Chem. | pmid:10636865 |
| Masterson C and Wood C | Pea chloroplast carnitine acetyltransferase. | 2000 | Proc. Biol. Sci. | pmid:10670945 |
| Starritt EC et al. | Sensitivity of CPT I to malonyl-CoA in trained and untrained human skeletal muscle. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:10710500 |
| Bayles DO and Wilkinson BJ | Osmoprotectants and cryoprotectants for Listeria monocytogenes. | 2000 | Lett. Appl. Microbiol. | pmid:10728555 |
| Seidman MD et al. | Biologic activity of mitochondrial metabolites on aging and age-related hearing loss. | 2000 | Am J Otol | pmid:10733178 |
| pmid:10750638 | ||||
| pmid:10761985 | ||||
| Stevens RD et al. | Assay for free and total carnitine in human plasma using tandem mass spectrometry. | 2000 | Clin. Chem. | pmid:10794762 |
| pmid:10803803 | ||||
| Jones AR and Bubb WA | Substrates for endogenous metabolism by mature boar spermatozoa. | 2000 | J. Reprod. Fertil. | pmid:10864822 |
| pmid:10877193 | ||||
| St Amand TA et al. | Pyruvate overrides inhibition of PDH during exercise after a low-carbohydrate diet. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:10913026 |
| Ishii T et al. | Anti-apoptotic effect of acetyl-l-carnitine and I-carnitine in primary cultured neurons. | 2000 | Jpn. J. Pharmacol. | pmid:10928324 |
| pmid:10994000 | ||||
| pmid:11014405 | ||||
| Duru NK et al. | Semen treatment with progesterone and/or acetyl-L-carnitine does not improve sperm motility or membrane damage after cryopreservation-thawing. | 2000 | Fertil. Steril. | pmid:11020512 |
| Pace S et al. | Pharmacokinetics of propionyl-L-carnitine in humans: evidence for saturable tubular reabsorption. | 2000 | Br J Clin Pharmacol | pmid:11069438 |
| Mancinelli A et al. | Disposition of L-carnitine and its short-chain esters, acetyl-L-carnitine and propionyl-L-carnitine, in the rat isolated perfused liver. | 2000 | Drug Metab. Dispos. | pmid:11095575 |
| pmid:11121899 | ||||
| pmid:11171924 | ||||
| pmid:11239702 | ||||
| Tomita K et al. | Enzymatic determination of acetylcarnitine for diagnostic applications. | 2001 | J Pharm Biomed Anal | pmid:11248512 |
| pmid:11315193 | ||||
| Benzerrouk R and Qureshi IA | Hepatic mitochondrial proteins in congenitally hyperammonemic spf mice: effect of acetyl-L-carnitine. | 2001 | Biosci. Biotechnol. Biochem. | pmid:11330659 |
| Parr TB | A new technique to elevate night time growth hormone release and a potential growth hormone feedback control loop. | 2001 | Med. Hypotheses | pmid:11388776 |
| Biagiotti G and Cavallini G | Acetyl-L-carnitine vs tamoxifen in the oral therapy of Peyronie's disease: a preliminary report. | 2001 | BJU Int. | pmid:11446848 |
| pmid:11462768 | ||||
| pmid:11478744 | ||||
| van Loon LJ et al. | The effects of increasing exercise intensity on muscle fuel utilisation in humans. | 2001 | J. Physiol. (Lond.) | pmid:11579177 |
| pmid:11592123 | ||||
| Kottlors M et al. | Valproic acid triggers acute rhabdomyolysis in a patient with carnitine palmitoyltransferase type II deficiency. | 2001 | Neuromuscul. Disord. | pmid:11595519 |
| Evans MK et al. | Effects of acetate infusion and hyperoxia on muscle substrate phosphorylation after onset of moderate exercise. | 2001 | Am. J. Physiol. Endocrinol. Metab. | pmid:11701427 |
| Fisher JS et al. | Activation of AMP kinase enhances sensitivity of muscle glucose transport to insulin. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:11739078 |
| Kido Y et al. | Functional relevance of carnitine transporter OCTN2 to brain distribution of L-carnitine and acetyl-L-carnitine across the blood-brain barrier. | 2001 | J. Neurochem. | pmid:11739607 |
| pmid:11757589 | ||||
| pmid:11768749 | ||||
| Grassi B et al. | Oxygen uptake on-kinetics in dog gastrocnemius in situ following activation of pyruvate dehydrogenase by dichloroacetate. | 2002 | J. Physiol. (Lond.) | pmid:11773328 |
| Hagen TM et al. | Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11854487 |
| Liu J et al. | Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11854488 |
| Liu J et al. | Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11854529 |
| pmid:11878804 | ||||
| Iossa S et al. | Acetyl-L-carnitine supplementation differently influences nutrient partitioning, serum leptin concentration and skeletal muscle mitochondrial respiration in young and old rats. | 2002 | J. Nutr. | pmid:11925454 |
| pmid:11947964 | ||||
| Chiechio S et al. | L-Acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors. | 2002 | Mol. Pharmacol. | pmid:11961116 |
| Liu J et al. | Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites. | 2002 | Ann. N. Y. Acad. Sci. | pmid:11976193 |
| Hagen TM et al. | Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid. | 2002 | Ann. N. Y. Acad. Sci. | pmid:11976222 |
| pmid:12047496 | ||||
| Watt MJ et al. | Intramuscular triacylglycerol, glycogen and acetyl group metabolism during 4 h of moderate exercise in man. | 2002 | J. Physiol. (Lond.) | pmid:12068055 |
| Tyni T et al. | Analysis of mitochondrial fatty acid oxidation intermediates by tandem mass spectrometry from intact mitochondria prepared from homogenates of cultured fibroblasts, skeletal muscle cells, and fresh muscle. | 2002 | Pediatr. Res. | pmid:12084849 |
| Graziano F et al. | Potential role of levocarnitine supplementation for the treatment of chemotherapy-induced fatigue in non-anaemic cancer patients. | 2002 | Br. J. Cancer | pmid:12085175 |
| pmid:12110958 | ||||
| Pop-Busui R et al. | Dissection of metabolic, vascular, and nerve conduction interrelationships in experimental diabetic neuropathy by cyclooxygenase inhibition and acetyl-L-carnitine administration. | 2002 | Diabetes | pmid:12145179 |
| pmid:12183043 | ||||
| pmid:12199155 | ||||
| Tolu P et al. | Effects of long-term acetyl-L-carnitine administration in rats: I. increased dopamine output in mesocorticolimbic areas and protection toward acute stress exposure. | 2002 | Neuropsychopharmacology | pmid:12225698 |
| Ori C et al. | Effects of acetyl-L-carnitine on regional cerebral glucose metabolism in awake rats. | 2002 | Brain Res. | pmid:12270513 |
| pmid:12352659 | ||||
| pmid:12392113 | ||||
| Watt MJ et al. | Carbohydrate ingestion reduces skeletal muscle acetylcarnitine availability but has no effect on substrate phosphorylation at the onset of exercise in man. | 2002 | J. Physiol. (Lond.) | pmid:12411537 |
| pmid:12414265 | ||||
| Roberts PA et al. | The temporal relationship between glycogen phosphorylase and activation of the pyruvate dehydrogenase complex during adrenaline infusion in resting canine skeletal muscle. | 2002 | J. Physiol. (Lond.) | pmid:12433969 |
| Sharman EH et al. | Reversal of biochemical and behavioral parameters of brain aging by melatonin and acetyl L-carnitine. | 2002 | Brain Res. | pmid:12445964 |
| Calvani M et al. | [L-acetylcarnitine treatment on fragile X patients hyperactive behaviour]. | 2001 | Rev Neurol | pmid:12447823 |
| pmid:12453624 | ||||
| pmid:12453625 | ||||
| pmid:12455197 | ||||
| pmid:12471321 | ||||
| pmid:12504925 | ||||
| pmid:12598816 | ||||
| Mattei B et al. | Pharmacologically induced enhancement of recurrent inhibition in humans: effects on motoneurone discharge patterns. | 2003 | J. Physiol. (Lond.) | pmid:12611926 |
| Masi F et al. | Effects of long-term acetyl-L-carnitine administration in rats--II: Protection against the disrupting effect of stress on the acquisition of appetitive behavior. | 2003 | Neuropsychopharmacology | pmid:12655313 |
| Beal MF | Bioenergetic approaches for neuroprotection in Parkinson's disease. | 2003 | Ann. Neurol. | pmid:12666097 |
| pmid:12689602 | ||||
| pmid:12716017 | ||||
| pmid:12796782 | ||||
| pmid:12804452 | ||||
| Pascale E et al. | Modulation of methylation in the FMR1 promoter region after long term treatment with L-carnitine and acetyl-L-carnitine. | 2003 | J. Med. Genet. | pmid:12807975 |
| pmid:12821151 | ||||
| pmid:12826272 |