Acetyl-l-carnitine

Acetyl-l-carnitine is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2904 references associated with Acetyl-l-carnitine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Acetyl-l-carnitine

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Acetyl-l-carnitine

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amino Acid Metabolism, Inborn Errors D000592 16 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Parkinson Disease D010300 53 associated lipids
Cleft Lip D002971 8 associated lipids
Proteostasis Deficiencies D057165 5 associated lipids
Total 7

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Acetyl-l-carnitine

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Authors Title Published Journal PubMed Link
pmid:12841930
Arafa HM and Sayed-Ahmed MM Protective role of carnitine esters against alcohol-induced gastric lesions in rats. 2003 Pharmacol. Res. pmid:12860448
Feher J et al. Mitotropic compounds for the treatment of age-related macular degeneration. The metabolic approach and a pilot study. 2003 Sep-Oct Ophthalmologica pmid:12913326
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pmid:1415515
pmid:1420631
Roe DS et al. Automated analysis for free and short-chain acylcarnitine in plasma with a centrifugal analyzer. 1992 Clin. Chem. pmid:1424113
MARQUIS NR and FRITZ IB THE DISTRIBUTION OF CARNITINE, ACETYLCARNITINE, AND CARNITINE ACETYLTRANSFERASE IN RAT TISSUES. 1965 J. Biol. Chem. pmid:14299646
MARQUIS NR and FRITZ IB EFFECTS OF TESTOSTERONE ON THE DISTRIBUTION OF CARNITINE, ACETYLCARNITINE, AND CARNITINE ACETYLTRANSFERASE IN TISSUES OF THE REPRODUCTIVE SYSTEM OF THE MALE RAT. 1965 J. Biol. Chem. pmid:14299647
pmid:14323607
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pmid:14624946
Pisano C et al. Paclitaxel and Cisplatin-induced neurotoxicity: a protective role of acetyl-L-carnitine. 2003 Clin. Cancer Res. pmid:14654561
Cui J et al. Effects of L-carnitine and its derivatives on postischemic cardiac function, ventricular fibrillation and necrotic and apoptotic cardiomyocyte death in isolated rat hearts. 2003 Mol. Cell. Biochem. pmid:14674702
Murakami K et al. Alterations of urinary acetylcarnitine in valproate-treated rats: the effect of L-carnitine supplementation. 1992 J. Child Neurol. pmid:1469250
Tanaka Y et al. Acetyl-L-carnitine supplementation restores decreased tissue carnitine levels and impaired lipid metabolism in aged rats. 2004 J. Lipid Res. pmid:14703509
pmid:14759641
Defani MA et al. Effect of acetyl-L-carnitine on VIP-ergic neurons in the jejunum submucous plexus of diabetic rats. 2003 Arq Neuropsiquiatr pmid:14762599
pmid:1482067
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Sakuma T et al. The urinary acylcarnitine profile in three cases of transient hyperammonemia of the newborn. 1992 Acta Paediatr. pmid:1498512
Vermeulen RC and Scholte HR Exploratory open label, randomized study of acetyl- and propionylcarnitine in chronic fatigue syndrome. 2004 Mar-Apr Psychosom Med pmid:15039515
pmid:15057979
pmid:15066157
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pmid:15138763
pmid:15153202
pmid:1515917
Rosenthal RE et al. Prevention of postischemic canine neurological injury through potentiation of brain energy metabolism by acetyl-L-carnitine. 1992 Stroke pmid:1519288
pmid:15193480
pmid:15219812
Leblanc PJ et al. Effects of 7 wk of endurance training on human skeletal muscle metabolism during submaximal exercise. 2004 J. Appl. Physiol. pmid:15220302
pmid:15223307
pmid:15226028
pmid:15236794
pmid:15238773
Ames BN Delaying the mitochondrial decay of aging. 2004 Ann. N. Y. Acad. Sci. pmid:15247055
pmid:15247059
pmid:15283472
pmid:1529006
Cavallini G et al. Cinnoxicam and L-carnitine/acetyl-L-carnitine treatment for idiopathic and varicocele-associated oligoasthenospermia. 2004 Sep-Oct J. Androl. pmid:15292108
pmid:15350642
Bastianetto S and Quirion R Natural antioxidants and neurodegenerative diseases. 2004 Front. Biosci. pmid:15353369
pmid:15363640
pmid:15383157
Roepstorff C et al. Malonyl-CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exercise. 2005 Am. J. Physiol. Endocrinol. Metab. pmid:15383373
pmid:1543717
Roberts PA et al. Acetyl-CoA provision and the acetyl group deficit at the onset of contraction in ischemic canine skeletal muscle. 2005 Am. J. Physiol. Endocrinol. Metab. pmid:15454400
Evans AM et al. Impact of hemodialysis on endogenous plasma and muscle carnitine levels in patients with end-stage renal disease. 2004 Kidney Int. pmid:15458447
Peluso G et al. Differential carnitine/acylcarnitine translocase expression defines distinct metabolic signatures in skeletal muscle cells. 2005 J. Cell. Physiol. pmid:15515015
pmid:15542726
pmid:15548429
Szutowicz A et al. Nerve growth factor and acetyl-L-carnitine evoked shifts in acetyl-CoA and cholinergic SN56 cell vulnerability to neurotoxic inputs. 2005 Jan 1-15 J. Neurosci. Res. pmid:15558747
pmid:15591000
pmid:15591001
Ames BN and Liu J Delaying the mitochondrial decay of aging with acetylcarnitine. 2004 Ann. N. Y. Acad. Sci. pmid:15591008
pmid:15591009
pmid:15591011
Bian F et al. Peroxisomal and mitochondrial oxidation of fatty acids in the heart, assessed from the 13C labeling of malonyl-CoA and the acetyl moiety of citrate. 2005 J. Biol. Chem. pmid:15611129
pmid:15616239
pmid:15641110
pmid:15732930
pmid:1573390
pmid:1573685
Tabolacci E et al. Differential epigenetic modifications in the FMR1 gene of the fragile X syndrome after reactivating pharmacological treatments. 2005 Eur. J. Hum. Genet. pmid:15741991
pmid:15771670
Kasumov T et al. Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver. 2005 Biochem. J. pmid:15773815
pmid:15774262
pmid:15801863
pmid:15830915
pmid:158625
Ghirardi O et al. Chemotherapy-induced allodinia: neuroprotective effect of acetyl-L-carnitine. 2005 May-Jun In Vivo pmid:15875786
pmid:15878327
Pracharoenwattana I et al. Arabidopsis peroxisomal citrate synthase is required for fatty acid respiration and seed germination. 2005 Plant Cell pmid:15923350
pmid:15929729
Feher J et al. Improvement of visual functions and fundus alterations in early age-related macular degeneration treated with a combination of acetyl-L-carnitine, n-3 fatty acids, and coenzyme Q10. 2005 May-Jun Ophthalmologica pmid:15947501
pmid:15966690
pmid:16024206
Bianchi G et al. Symptomatic and neurophysiological responses of paclitaxel- or cisplatin-induced neuropathy to oral acetyl-L-carnitine. 2005 Eur. J. Cancer pmid:16039110
Ghirardi O et al. Acetyl-L-Carnitine prevents and reverts experimental chronic neurotoxicity induced by oxaliplatin, without altering its antitumor properties. 2005 Jul-Aug Anticancer Res. pmid:16080512
pmid:16120381
pmid:1616022
pmid:16169400
Zanelli SA et al. Mechanisms of ischemic neuroprotection by acetyl-L-carnitine. 2005 Ann. N. Y. Acad. Sci. pmid:16179519
pmid:16235010
pmid:16256963
Cavallini G et al. Acetyl-L-carnitine plus propionyl-L-carnitine improve efficacy of sildenafil in treatment of erectile dysfunction after bilateral nerve-sparing radical retropubic prostatectomy. 2005 Urology pmid:16286128
pmid:16316746
Kobayashi D et al. Carnitine/organic cation transporter OCTN2-mediated transport of carnitine in primary-cultured epididymal epithelial cells. 2005 Reproduction pmid:16322553
Schreiber BD Debate forum: levocarnitine therapy is rational and justified in selected dialysis patients. 2006 Blood Purif. pmid:16361853
Flatters SJ et al. Acetyl-L-carnitine prevents and reduces paclitaxel-induced painful peripheral neuropathy. 2006 Neurosci. Lett. pmid:16406309
pmid:16413418