Acetyl-l-carnitine

Acetyl-l-carnitine is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2904 references associated with Acetyl-l-carnitine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Acetyl-l-carnitine

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Acetyl-l-carnitine

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amino Acid Metabolism, Inborn Errors D000592 16 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Parkinson Disease D010300 53 associated lipids
Cleft Lip D002971 8 associated lipids
Proteostasis Deficiencies D057165 5 associated lipids
Total 7

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Acetyl-l-carnitine

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Authors Title Published Journal PubMed Link
Li S and Laher I Exercise Pills: At the Starting Line. 2015 Trends Pharmacol. Sci. pmid:26439443
Huemer M et al. Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines. 2015 J. Inherit. Metab. Dis. pmid:25762406
Schooneman MG et al. Transorgan fluxes in a porcine model reveal a central role for liver in acylcarnitine metabolism. 2015 Am. J. Physiol. Endocrinol. Metab. pmid:26037250
Sarkar S et al. Histopathological and electrophysiological indices of rotenone-evoked dopaminergic toxicity: Neuroprotective effects of acetyl-L-carnitine. 2015 Neurosci. Lett. pmid:26321151
Lindsay KL et al. Longitudinal Metabolomic Profiling of Amino Acids and Lipids across Healthy Pregnancy. 2015 PLoS ONE pmid:26716698
Robinson BL et al. Opposing effects of ketamine and acetyl L-carnitine on the serotonergic system of zebrafish. 2015 Neurosci. Lett. pmid:26365406
Samms RJ et al. Dual effects of fibroblast growth factor 21 on hepatic energy metabolism. 2015 J. Endocrinol. pmid:26294388
De Luca A et al. Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells. 2015 Oncotarget pmid:26087310
Macconi D et al. Sirtuin3 Dysfunction Is the Key Determinant of Skeletal Muscle Insulin Resistance by Angiotensin II. 2015 PLoS ONE pmid:25993470
Li S et al. Acetyl-L-carnitine in the treatment of peripheral neuropathic pain: a systematic review and meta-analysis of randomized controlled trials. 2015 PLoS ONE pmid:25751285
Kerner J et al. Acetyl-L-carnitine increases mitochondrial protein acetylation in the aged rat heart. 2015 Mech. Ageing Dev. pmid:25660059
Wu J et al. TGF-β1 induces senescence of bone marrow mesenchymal stem cells via increase of mitochondrial ROS production. 2014 BMC Dev. Biol. pmid:24886313
Phillipson OT Management of the aging risk factor for Parkinson's disease. 2014 Neurobiol. Aging pmid:24246717
Zhang H et al. Metabolomic analysis of biochemical changes in the plasma and urine of collagen-induced arthritis in rats after treatment with Huang-Lian-Jie-Du-Tang. 2014 J Ethnopharmacol pmid:24709313
Farahpour MR and Ghayour SJ Effect of in situ delivery of acetyl-L-carnitine on peripheral nerve regeneration and functional recovery in transected sciatic nerve in rat. 2014 Int J Surg pmid:25448663
Lindeboom L et al. Long-echo time MR spectroscopy for skeletal muscle acetylcarnitine detection. 2014 J. Clin. Invest. pmid:25271624
Dodd MS et al. Impaired in vivo mitochondrial Krebs cycle activity after myocardial infarction assessed using hyperpolarized magnetic resonance spectroscopy. 2014 Circ Cardiovasc Imaging pmid:25201905
Callander N et al. Acetyl-L-carnitine (ALCAR) for the prevention of chemotherapy-induced peripheral neuropathy in patients with relapsed or refractory multiple myeloma treated with bortezomib, doxorubicin and low-dose dexamethasone: a study from the Wisconsin Oncology Network. 2014 Cancer Chemother. Pharmacol. pmid:25168296
Bigford GE and Del Rossi G Supplemental substances derived from foods as adjunctive therapeutic agents for treatment of neurodegenerative diseases and disorders. 2014 Adv Nutr pmid:25022989
Furuichi Y et al. Imaging mass spectrometry reveals fiber-specific distribution of acetylcarnitine and contraction-induced carnitine dynamics in rat skeletal muscles. 2014 Biochim. Biophys. Acta pmid:24882639