Acetyl-l-carnitine

Acetyl-l-carnitine is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 2904 references associated with Acetyl-l-carnitine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Acetyl-l-carnitine

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Acetyl-l-carnitine

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amino Acid Metabolism, Inborn Errors D000592 16 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Parkinson Disease D010300 53 associated lipids
Cleft Lip D002971 8 associated lipids
Proteostasis Deficiencies D057165 5 associated lipids
Total 7

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Acetyl-l-carnitine

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Authors Title Published Journal PubMed Link
Bayles DO and Wilkinson BJ Osmoprotectants and cryoprotectants for Listeria monocytogenes. 2000 Lett. Appl. Microbiol. pmid:10728555
Mroczkowska JE et al. Blood-brain barrier controls carnitine level in the brain: a study on a model system with RBE4 cells. 2000 Biochem. Biophys. Res. Commun. pmid:10623637
Ganapathy ME et al. beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter. 2000 J. Biol. Chem. pmid:10636865
Seidman MD et al. Biologic activity of mitochondrial metabolites on aging and age-related hearing loss. 2000 Am J Otol pmid:10733178
Masterson C and Wood C Pea chloroplast carnitine acetyltransferase. 2000 Proc. Biol. Sci. pmid:10670945
Starritt EC et al. Sensitivity of CPT I to malonyl-CoA in trained and untrained human skeletal muscle. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:10710500
Duru NK et al. Semen treatment with progesterone and/or acetyl-L-carnitine does not improve sperm motility or membrane damage after cryopreservation-thawing. 2000 Fertil. Steril. pmid:11020512
Acetyl-L-carnitine. 1999 Altern Med Rev pmid:10608918
Howlett RA et al. Skeletal muscle metabolism during high-intensity sprint exercise is unaffected by dichloroacetate or acetate infusion. 1999 J. Appl. Physiol. pmid:10562618
Parolin ML et al. Regulation of skeletal muscle glycogen phosphorylase and PDH during maximal intermittent exercise. 1999 Am. J. Physiol. pmid:10567017
Paradies G et al. The effect of aging and acetyl-L-carnitine on the pyruvate transport and oxidation in rat heart mitochondria. 1999 FEBS Lett. pmid:10431808
Kidd PM A review of nutrients and botanicals in the integrative management of cognitive dysfunction. 1999 Altern Med Rev pmid:10383479
Wu X et al. Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter. 1999 J. Pharmacol. Exp. Ther. pmid:10454528
Palmieri L et al. Identification of the mitochondrial carnitine carrier in Saccharomyces cerevisiae. 1999 FEBS Lett. pmid:10622748
Löster H et al. Effects of L-carnitine and its acetyl and propionyl esters on ATP and PCr levels of isolated rat hearts perfused without fatty acids and investigated by means of 31P-NMR spectroscopy. 1999 Mol. Cell. Biochem. pmid:10569188
Srikanth V et al. Effects of ethanol treatment on epididymal secretory products and sperm maturation in albino rats. 1999 J. Pharmacol. Exp. Ther. pmid:9918552
Aureli T et al. Entry of [(1,2-13C2)acetyl]-L-carnitine in liver tricarboxylic acid cycle and lipogenesis: a study by 13C NMR spectroscopy in conscious, freely moving rats. 1999 Eur. J. Biochem. pmid:10429215
Putman CT et al. Pyruvate dehydrogenase activation in inactive muscle during and after maximal exercise in men. 1999 Am. J. Physiol. pmid:10070014
Mawal YR et al. Restoration of hepatic cytochrome c oxidase activity and expression with acetyl-L-carnitine treatment in spf mice with an ornithine transcarbamylase deficiency. 1998 Biochem. Pharmacol. pmid:9714304
Nakamura J et al. Polyol pathway hyperactivity is closely related to carnitine deficiency in the pathogenesis of diabetic neuropathy of streptozotocin-diabetic rats. 1998 J. Pharmacol. Exp. Ther. pmid:9864270
Ricciolini R et al. Role of acetyl-L-carnitine in rat brain lipogenesis: implications for polyunsaturated fatty acid biosynthesis. 1998 J. Neurochem. pmid:9832150
Hagen TM et al. Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9689120
Tamai I et al. Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2. 1998 J. Biol. Chem. pmid:9685390
Timmons JA et al. Substrate availability limits human skeletal muscle oxidative ATP regeneration at the onset of ischemic exercise. 1998 J. Clin. Invest. pmid:9421469
El Banani H et al. Ionic and metabolic imbalance as potential factors of ischemia reperfusion injury. 1998 Am. J. Cardiol. pmid:9737483
Howlett RA et al. Regulation of skeletal muscle glycogen phosphorylase and PDH at varying exercise power outputs. 1998 Am. J. Physiol. pmid:9688676
Horiuchi M et al. Secondary abnormality of carnitine biosynthesis results from carnitine reabsorptional system defect in juvenile visceral steatosis mice. 1997 Biochim. Biophys. Acta pmid:9540857
Capecchi PL et al. Carnitines increase plasma levels of adenosine and ATP in humans. 1997 Vasc Med pmid:9546959
Lligona-Trulla L et al. Acetyl-L-carnitine flux to lipids in cells estimated using isotopomer spectral analysis. 1997 J. Lipid Res. pmid:9254070
Abdel-aleem S et al. Reduced effects of L-carnitine on glucose and fatty acid metabolism in myocytes isolated from diabetic rats. 1997 Horm. Metab. Res. pmid:9370110
Timmons JA et al. Metabolic responses from rest to steady state determine contractile function in ischemic skeletal muscle. 1997 Am. J. Physiol. pmid:9277374
Valoti M et al. Effects of carnitine and its derivatives on gastric acid secretion in rats. 1996 Nov-Dec Pharmacol. Res. pmid:9076846
Eaton S et al. The effect of respiratory chain impairment of beta-oxidation in rat heart mitochondria. 1996 Biochem. J. pmid:8912705
Brevetti G et al. Carnitine-related alterations in patients with intermittent claudication: indication for a focused carnitine therapy. 1996 Circulation pmid:8653874
Sima AA et al. Primary preventive and secondary interventionary effects of acetyl-L-carnitine on diabetic neuropathy in the bio-breeding Worcester rat. 1996 J. Clin. Invest. pmid:8621774
Timmons JA et al. Increased acetyl group availability enhances contractile function of canine skeletal muscle during ischemia. 1996 J. Clin. Invest. pmid:8609248
Itoh T et al. Effect of carnitine administration on glycine metabolism in patients with isovaleric acidemia: significance of acetylcarnitine determination to estimate the proper carnitine dose. 1996 Tohoku J. Exp. Med. pmid:8875766
Requero MA et al. Differential penetration of fatty acyl-coenzyme A and fatty acylcarnitines into phospholipid monolayers. 1995 FEBS Lett. pmid:8001684
Virmani MA et al. Protective actions of L-carnitine and acetyl-L-carnitine on the neurotoxicity evoked by mitochondrial uncoupling or inhibitors. 1995 Pharmacol. Res. pmid:8736490
Cotter MA et al. Effects of acetyl- and proprionyl-L-carnitine on peripheral nerve function and vascular supply in experimental diabetes. 1995 Metab. Clin. Exp. pmid:7666797
Paradies G et al. Carnitine-acylcarnitine translocase activity in cardiac mitochondria from aged rats: the effect of acetyl-L-carnitine. 1995 Mech. Ageing Dev. pmid:8788238
Diep QN et al. Formation of pivaloylcarnitine in isolated rat heart cells. 1995 Biochim. Biophys. Acta pmid:7488636
Wawrzeńczyk A et al. Effect of gamma-aminobutyric acid on the carnitine metabolism in neural cells. 1995 Biochem. Biophys. Res. Commun. pmid:7646490
Pomponi MG and Neri G Butyrate and acetyl-carnitine inhibit the cytogenetic expression of the fragile X in vitro. 1994 Am. J. Med. Genet. pmid:7943015
Paradies G et al. Effect of aging and acetyl-L-carnitine on the activity of cytochrome oxidase and adenine nucleotide translocase in rat heart mitochondria. 1994 FEBS Lett. pmid:8070566
Matsui S et al. Urinary carnitine excretion in patients with heart failure. 1994 Clin Cardiol pmid:8070147
De Maria P et al. Effect of the addition of electrolytes on the partition coefficients, activity coefficients, and acid dissociation constants of carnitine and its acetyl and propionyl derivatives. 1994 J Pharm Sci pmid:8071833
Bähring R et al. GABA-activated chloride currents of postnatal mouse retinal ganglion cells are blocked by acetylcholine and acetylcarnitine: how specific are ion channels in immature neurons? 1994 Eur. J. Neurosci. pmid:7952289
Kamimori H et al. Determination of carnitine and saturated-acyl group carnitines in human urine by high-performance liquid chromatography with fluorescence detection. 1994 Anal. Biochem. pmid:8074302
Tassani V et al. Anaplerotic effect of propionyl carnitine in rat heart mitochondria. 1994 Biochem. Biophys. Res. Commun. pmid:8135845