Palmitoylcarnitine

Palmitoylcarnitine is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 1026 references associated with Palmitoylcarnitine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Palmitoylcarnitine

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Palmitoylcarnitine

MeSH term MeSH ID Detail
Mitochondrial Diseases D028361 25 associated lipids
Coronary Disease D003327 70 associated lipids
Insulin Resistance D007333 99 associated lipids
Total 3

NCBI Entrez Crosslinks

All references with Palmitoylcarnitine

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Nałecz KA et al. Effect of palmitoylcarnitine on the cellular differentiation, proliferation and protein kinase C activity in neuroblastoma nb-2a cells. 1997 Acta Neurobiol Exp (Wars) pmid:9519544
Kinnula VL and Hassinen I Effect of chronic hypoxia on hepatic triacylglycerol concentration and mitochondrial fatty acid oxidizing capacity in liver and heart. 1978 Acta Physiol. Scand. pmid:626089
Farstad M and Berge R On the capacity of the beta-oxidation of palmitate and palmitoyl-esters in rat liver mitochondria. 1978 Acta Physiol. Scand. pmid:31061
Pitts BJ and Okhuysen CH Effects of palmitoyl carnitine and LPC on cardiac sarcolemmal Na+-K+-ATPase. 1984 Am. J. Physiol. pmid:6093598
Xu Z and Rozanski GJ K+ current inhibition by amphiphilic fatty acid metabolites in rat ventricular myocytes. 1998 Am. J. Physiol. pmid:9843728
Abdul-Ghani MA et al. Deleterious action of FA metabolites on ATP synthesis: possible link between lipotoxicity, mitochondrial dysfunction, and insulin resistance. 2008 Am. J. Physiol. Endocrinol. Metab. pmid:18593850
Ojuka E et al. Measurement of β-oxidation capacity of biological samples by respirometry: a review of principles and substrates. 2016 Am. J. Physiol. Endocrinol. Metab. pmid:26908505
Schooneman MG et al. Transorgan fluxes in a porcine model reveal a central role for liver in acylcarnitine metabolism. 2015 Am. J. Physiol. Endocrinol. Metab. pmid:26037250
Kanaley JA et al. Hyperinsulinemia and skeletal muscle fatty acid trafficking. 2013 Am. J. Physiol. Endocrinol. Metab. pmid:23820622
Jørgensen W et al. Progression of type 2 diabetes in GK rats affects muscle and liver mitochondria differently: pronounced reduction of complex II flux is observed in liver only. 2012 Am. J. Physiol. Endocrinol. Metab. pmid:22713504
Johnson G et al. Influence of intensity of food restriction on skeletal muscle mitochondrial energy metabolism in rats. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16621897
Tominaga H et al. Different effects of palmitoyl-L-carnitine and palmitoyl-CoA on mitochondrial function in rat ventricular myocytes. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18469143
Schaeffer PJ et al. Impaired contractile function and calcium handling in hearts of cardiac-specific calcineurin b1-deficient mice. 2009 Am. J. Physiol. Heart Circ. Physiol. pmid:19700627
Lehman JJ et al. The transcriptional coactivator PGC-1alpha is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18487436
Morand R et al. Quantification of plasma carnitine and acylcarnitines by high-performance liquid chromatography-tandem mass spectrometry using online solid-phase extraction. 2013 Anal Bioanal Chem pmid:23995505
Squire RS Synthesis and purification of radioactive fatty acylcarnitines of high specific activity. 1991 Anal. Biochem. pmid:1952050
Nolte L et al. Carnitine palmitoyltransferase I activity monitoring in fibroblasts and leukocytes using electrospray ionization mass spectrometry. 1998 Anal. Biochem. pmid:9473275
Kulier AH et al. Multiple agents potentiate alpha1-adrenoceptor-induced conduction depression in canine cardiac purkinje fibers. 2000 Anesthesiology pmid:10839923
Nguyen UT et al. Small-molecule modulators of Listeria monocytogenes biofilm development. 2012 Appl. Environ. Microbiol. pmid:22194285
Gandour RD et al. Hemipalmitoylcarnitinium, a strong competitive inhibitor of purified hepatic carnitine palmitoyltransferase. 1988 Arch. Biochem. Biophys. pmid:3214166
Yeh YY and Zee P Fatty acid oxidation in isolated rat liver mitochondria. Developmental changes and their relation to hepatic levels of carnitine and glycogen and to carnitine acyltransferase activity. 1979 Arch. Biochem. Biophys. pmid:507829
Wood JM Effects of palmityl coenzyme A and palmitylcarnitine on phosphorylating respiration in heart mitochondria. 1978 Arch. Biochem. Biophys. pmid:626500
Olson MS et al. The regulation of pyruvate dehydrogenase by fatty acids in isolated rabbit heart mitochondria. 1978 Arch. Biochem. Biophys. pmid:207223
Eacho PI and Foxworthy PS Inhibition of hepatic fatty acid oxidation by bezafibrate and bezafibroyl CoA. 1988 Biochem. Biophys. Res. Commun. pmid:3264699
Kanter P et al. Epidermal growth factor and tumor promoters prevent DNA fragmentation by different mechanisms. 1984 Biochem. Biophys. Res. Commun. pmid:6608349
Arduini A et al. Palmitoyl-L-carnitine, a metabolic intermediate of the fatty acid incorporation pathway in erythrocyte membrane phospholipids. 1990 Biochem. Biophys. Res. Commun. pmid:2256917
Abe K et al. Phosphorylation of coagulation factor II by phospholipid/Ca(2+)-dependent protein kinase (protein kinase C). 1991 Biochem. Biophys. Res. Commun. pmid:2039497
Grove DS and Mastro AM Prevention of the TPA-mediated down-regulation of protein kinase C. 1988 Biochem. Biophys. Res. Commun. pmid:3348799
Ashour B and Hansford RG Effect of fatty acids and ketones on the activity of pyruvate dehydrogenase in skeletal-muscle mitochondria. 1983 Biochem. J. pmid:6138029
Bauché F et al. 2-Mercaptoacetate administration depresses the beta-oxidation pathway through an inhibition of long-chain acyl-CoA dehydrogenase activity. 1981 Biochem. J. pmid:7317017
Brady PS et al. Characterization of hepatic carnitine palmitoyltransferase. Use of bromoacyl derivatives and antibodies. 1987 Biochem. J. pmid:3593221
Brass EP and Hoppel CL Effect of carnitine on mitochondrial oxidation of palmitoylearnitine. 1980 Biochem. J. pmid:7396873
Zammit VA Effects of the mode of addition of acyl-CoA on the initial rate of formation of acylcarnitine in the presence of carnitine by intact rat liver mitochondria in vitro. 1985 Biochem. J. pmid:4038262
Foxworthy PS and Eacho PI Inhibition of hepatic fatty acid oxidation at carnitine palmitoyltransferase I by the peroxisome proliferator 2-hydroxy-3-propyl-4-[6-(tetrazol-5-yl) hexyloxy]acetophenone. 1988 Biochem. J. pmid:3415664
Chen SC et al. Purification and characterization of secretory phospholipase B, lysophospholipase and lysophospholipase/transacylase from a virulent strain of the pathogenic fungus Cryptococcus neoformans. 2000 Biochem. J. pmid:10749672
Eaton S et al. Intramitochondrial control of the oxidation of hexadecanoate in skeletal muscle. A study of the acyl-CoA esters which accumulate during rat skeletal-muscle mitochondrial beta-oxidation of [U-14C]hexadecanoate and [U-14C]hexadecanoyl-carnitine. 1993 Biochem. J. pmid:8424753
Hovik R et al. Effects of thia-substituted fatty acids on mitochondrial and peroxisomal beta-oxidation. Studies in vivo and in vitro. 1990 Biochem. J. pmid:2396976
Moreno-Sánchez R et al. Influence of NAD-linked dehydrogenase activity on flux through oxidative phosphorylation. 1990 Biochem. J. pmid:2363681
Halestrap AP The regulation of the oxidation of fatty acids and other substrates in rat heart mitochondria by changes in the matrix volume induced by osmotic strength, valinomycin and Ca2+. 1987 Biochem. J. pmid:3663110
Veitch K et al. Effects of riboflavin deficiency and clofibrate treatment on the five acyl-CoA dehydrogenases in rat liver mitochondria. 1988 Biochem. J. pmid:3178769
Watmough NJ et al. Skeletal muscle mitochondrial beta-oxidation. A study of the products of oxidation of [U-14C]hexadecanoate by h.p.l.c. using continuous on-line radiochemical detection. 1988 Biochem. J. pmid:3178728
Ross NS and Hoppel CL Acyl-CoA dehydrogenase activity in the riboflavin-deficient rat. Effects of starvation. 1987 Biochem. J. pmid:3663132
Ramsay RR and Tubbs PK Aggregation of submitochondrial particles by heparin and its application to the study of carnitine transport. 1986 Biochem. J. pmid:3741385
Osmundsen H and Bjørnstad K Inhibitory effects of some long-chain unsaturated fatty acids on mitochondrial beta-oxidation. Effects of streptozotocin-induced diabetes on mitochondrial beta-oxidation of polyunsaturated fatty acids. 1985 Biochem. J. pmid:4052049
Berge RK et al. Intracellular localization of long-chain acyl-coenzyme A hydrolase and acyl-L-carnitine hydrolase in brown adipose tissue from guinea pigs. 1979 Biochem. J. pmid:41517
Berge RK and Døssland B Differences between microsomal and mitochondrial-matrix palmitoyl-coenzyme A hydrolase, and palmitoyl-L-carnitine hydrolase from rat liver. 1979 Biochem. J. pmid:39553
Wolkowicz PE and McMillin-Wood J Respiration-dependent calcium ion uptake by two preparations of cardiac mitochondria. Effects of palmitoyl-coenzyme A and palmitoylcarnitine on calcium ion cycling and nicotinamide nucleotide reduction state. 1980 Biochem. J. pmid:6154457
Halestrap AP and Dunlop JL Intramitochondrial regulation of fatty acid beta-oxidation occurs between flavoprotein and ubiquinone. A role for changes in the matrix volume. 1986 Biochem. J. pmid:3827814
Gualberto A and Saggerson ED Differentiation of rapid and slower-acting effects of insulin on mitochondrial processes in brown adipose tissue from streptozotocin-diabetic rats. 1989 Biochem. J. pmid:2649091