MeSH term | MeSH ID | Detail |
---|---|---|
Coronary Disease | D003327 | 70 associated lipids |
Insulin Resistance | D007333 | 99 associated lipids |
Mitochondrial Diseases | D028361 | 25 associated lipids |
Total
3
Palmitoylcarnitine is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Palmitoylcarnitine
MeSH term | MeSH ID | Detail |
---|---|---|
Coronary Disease | D003327 | 70 associated lipids |
Insulin Resistance | D007333 | 99 associated lipids |
Mitochondrial Diseases | D028361 | 25 associated lipids |
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Felser A et al. | Hepatic toxicity of dronedarone in mice: role of mitochondrial β-oxidation. | 2014 | Toxicology | pmid:24881592 |
Quinlan CL et al. | Sites of reactive oxygen species generation by mitochondria oxidizing different substrates. | 2013 | Redox Biol | pmid:24024165 |
Al-Bakheit A et al. | Accumulation of Palmitoylcarnitine and Its Effect on Pro-Inflammatory Pathways and Calcium Influx in Prostate Cancer. | 2016 | Prostate | pmid:27403764 |
Leonardi R et al. | Activation of human mitochondrial pantothenate kinase 2 by palmitoylcarnitine. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:17242360 |
Katoh N et al. | Substrate proteins for calmodulin-sensitive and phospholipid-sensitive Ca2+-dependent protein kinases in heart, and inhibition of their phosphorylation by palmitoylcarnitine. | 1981 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6946429 |
Valentine MA et al. | Expression of the human B-cell surface protein CD20: alteration by phorbol 12-myristate 13-acetate. | 1987 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3500472 |
Ellis CJ et al. | Myoglobinuria: the importance of reaching a firm diagnosis--a patient with defective fatty acid oxidation. | 1990 | Postgrad Med J | pmid:2362895 |
Lou PH et al. | The mechanism of Intralipid®-mediated cardioprotection complex IV inhibition by the active metabolite, palmitoylcarnitine, generates reactive oxygen species and activates reperfusion injury salvage kinases. | 2014 | PLoS ONE | pmid:24498043 |
Voss U et al. | Enteric neuropathy can be induced by high fat diet in vivo and palmitic acid exposure in vitro. | 2013 | PLoS ONE | pmid:24312551 |
van Eunen K et al. | Biochemical competition makes fatty-acid β-oxidation vulnerable to substrate overload. | 2013 | PLoS Comput. Biol. | pmid:23966849 |
Endlicher R et al. | Peroxidative damage of mitochondrial respiration is substrate-dependent. | 2009 | Physiol Res | pmid:19093725 |
Cervinková Z et al. | Inhibition of palmityl carnitine oxidation in rat liver mitochondria by tert-butyl hydroperoxide. | 2008 | Physiol Res | pmid:17465699 |
O'Hagan DT et al. | Nasal absorption enhancers for biosynthetic human growth hormone in rats. | 1990 | Pharm. Res. | pmid:2395807 |
Primassin S et al. | Carnitine supplementation induces acylcarnitine production in tissues of very long-chain acyl-CoA dehydrogenase-deficient mice, without replenishing low free carnitine. | 2008 | Pediatr. Res. | pmid:18317232 |
Gregersen N | Studies on the effects of saturated and unsaturated short-chain monocarboxylic acids on the energy metabolism of rat liver mitochondria. | 1979 | Pediatr. Res. | pmid:514688 |
Cortright RN et al. | Skeletal muscle fat oxidation is increased in African-American and white women after 10 days of endurance exercise training. | 2006 | Obesity (Silver Spring) | pmid:16899801 |
Dixen K et al. | ERRγ enhances UCP1 expression and fatty acid oxidation in brown adipocytes. | 2013 | Obesity (Silver Spring) | pmid:23404793 |
Muraki K | [Analyses of Ca-related ion channel currents and their involvement in Ca mobilization in smooth muscle and endothelial cells]. | 2003 | Nippon Yakurigaku Zasshi | pmid:12673948 |
Abiko Y et al. | [A new approach to the understanding of the mechanism of ischemia/reperfusion damage in the heart and the effects of anti-ischemic drugs]. | 1996 | Nippon Yakurigaku Zasshi | pmid:8940701 |
Szczepankowska D and Nałecz KA | Palmitoylcarnitine modulates palmitoylation of proteins: implication for differentiation of neural cells. | 2003 | Neurochem. Res. | pmid:12675156 |
Bonnefont JP et al. | Bezafibrate for an inborn mitochondrial beta-oxidation defect. | 2009 | N. Engl. J. Med. | pmid:19228633 |
Shao Y et al. | Lipid metabolites and their differential pro-arrhythmic profiles: of importance in the development of a new anti-arrhythmic pharmacology. | 2014 | Mol. Cell. Biochem. | pmid:24771065 |
Ziolo MT et al. | Effects of arrhythmogenic lipid metabolites on the L-type calcium current of diabetic vs. non-diabetic rat hearts. | 2001 | Mol. Cell. Biochem. | pmid:11451378 |
Brosnan JT and Reid K | Inhibition of palmitoylcarnitine oxidation by pyruvate in rat heart mitochondria. | 1985 | Metab. Clin. Exp. | pmid:3999980 |
Privette JD et al. | Fatty acid oxidation by skeletal muscle homogenates from morbidly obese black and white American women. | 2003 | Metab. Clin. Exp. | pmid:12800100 |
Hara A et al. | Beneficial effects of dilazep on the palmitoyl-L-carnitine-induced derangements in isolated, perfused rat heart: comparison with tetrodotoxin. | 1997 | Jpn. J. Pharmacol. | pmid:9243322 |
Matsui K et al. | Effect of l-carnitine chloride and its acetyl derivative on the electrophysiological derangement induced by palmityl-l-carnitine in isolated canine ventricular muscle. | 1985 | Jpn. J. Pharmacol. | pmid:4087570 |
Dumonteil E et al. | Effects of palmitoyl carnitine and related metabolites on the avian Ca(2+)-ATPase and Ca2+ release channel. | 1994 | J. Physiol. (Lond.) | pmid:7990033 |
Muraki K and Imaizumi Y | A novel action of palmitoyl-L-carnitine in human vascular endothelial cells. | 2003 | J. Pharmacol. Sci. | pmid:12890891 |
Bergstrand H et al. | Modulation of human basophil histamine release by protein kinase C inhibitors differs with secretagogue and with inhibitor. | 1992 | J. Pharmacol. Exp. Ther. | pmid:1372047 |
Wu Y et al. | The late Na+ current (INa) inhibitor ranolazine attenuates effects of palmitoyl-L-carnitine to increase late INa and cause ventricular diastolic dysfunction. | 2009 | J. Pharmacol. Exp. Ther. | pmid:19403851 |
Duizer E et al. | Absorption enhancement, structural changes in tight junctions and cytotoxicity caused by palmitoyl carnitine in Caco-2 and IEC-18 cells. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9765361 |
Hara A et al. | Protective effects of dilazep and its derivative K-7259 on the haemolysis induced by amphiphiles in rat erythrocytes. | 1997 | J. Pharm. Pharmacol. | pmid:9379361 |
Wenzel U et al. | Increased carnitine-dependent fatty acid uptake into mitochondria of human colon cancer cells induces apoptosis. | 2005 | J. Nutr. | pmid:15930461 |
Schmidt I and Herpin P | Carnitine palmitoyltransferase I (CPT I) activity and its regulation by malonyl-CoA are modulated by age and cold exposure in skeletal muscle mitochondria from newborn pigs. | 1998 | J. Nutr. | pmid:9566999 |
Clarke B et al. | On the roles of long-chain acyl carnitine accumulation and impaired glucose utilization in ischaemic contracture development and tissue damage in the guinea-pig heart. | 1996 | J. Mol. Cell. Cardiol. | pmid:8745225 |
Netticadan T et al. | Palmitoyl carnitine increases intracellular calcium in adult rat cardiomyocytes. | 1999 | J. Mol. Cell. Cardiol. | pmid:10403753 |
Williams ES and Li TK | The effect of chronic alcohol administration on fatty acid metabolism and pyruvate oxidation of heart mitochondria. | 1977 | J. Mol. Cell. Cardiol. | pmid:563474 |
Fantini E et al. | Some biochemical aspects of the protective effect of trimetazidine on rat cardiomyocytes during hypoxia and reoxygenation. | 1994 | J. Mol. Cell. Cardiol. | pmid:7799450 |
Zhang XJ et al. | Measurement of precursor enrichment for calculating intramuscular triglyceride fractional synthetic rate. | 2012 | J. Lipid Res. | pmid:21934122 |
Shi X et al. | Lipidomic profiling reveals protective function of fatty acid oxidation in cocaine-induced hepatotoxicity. | 2012 | J. Lipid Res. | pmid:22904346 |
Sun D et al. | Measurement of stable isotopic enrichment and concentration of long-chain fatty acyl-carnitines in tissue by HPLC-MS. | 2006 | J. Lipid Res. | pmid:16301738 |
Arduini A et al. | High performance liquid chromatography of long-chain acylcarnitine and phospholipids in fatty acid turnover studies. | 1996 | J. Lipid Res. | pmid:8728329 |
Ballantyne JS and Storey KB | Mitochondria from the hepatopancreas of the marine clam Mercenaria mercenaria: substrate preferences and salt and pH effects on the oxidation of palmitoyl-L-carnitine and succinate. | 1984 | J. Exp. Zool. | pmid:6736891 |
Liu H et al. | Cysteine-scanning mutagenesis of muscle carnitine palmitoyltransferase I reveals a single cysteine residue (Cys-305) is important for catalysis. | 2005 | J. Biol. Chem. | pmid:15579906 |
Sekoguchi E et al. | A novel mitochondrial carnitine-acylcarnitine translocase induced by partial hepatectomy and fasting. | 2003 | J. Biol. Chem. | pmid:12882971 |
Murthy MS and Pande SV | Mechanism of carnitine acylcarnitine translocase-catalyzed import of acylcarnitines into mitochondria. | 1984 | J. Biol. Chem. | pmid:6430896 |
Sabbagh E et al. | 3-Mercaptopropionic acid, a potent inhibitor of fatty acid oxidation in rat heart mitochondria. | 1985 | J. Biol. Chem. | pmid:3997873 |
Mak IT et al. | Potentiation of free radical-induced lipid peroxidative injury to sarcolemmal membranes by lipid amphiphiles. | 1986 | J. Biol. Chem. | pmid:3003057 |
Bussolino F et al. | Platelet-activating factor enhances complement-dependent phagocytosis of diamide-treated erythrocytes by human monocytes through activation of protein kinase C and phosphorylation of complement receptor type one (CR1). | 1989 | J. Biol. Chem. | pmid:2600088 |