Palmitoylcarnitine

Palmitoylcarnitine is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 1026 references associated with Palmitoylcarnitine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Palmitoylcarnitine

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Palmitoylcarnitine

MeSH term MeSH ID Detail
Coronary Disease D003327 70 associated lipids
Insulin Resistance D007333 99 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Total 3

NCBI Entrez Crosslinks

All references with Palmitoylcarnitine

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Authors Title Published Journal PubMed Link
Wenderska IB et al. Palmitoyl-DL-carnitine is a multitarget inhibitor of Pseudomonas aeruginosa biofilm development. 2011 Chembiochem pmid:22045628
Nguyen UT et al. Small-molecule modulators of Listeria monocytogenes biofilm development. 2012 Appl. Environ. Microbiol. pmid:22194285
Tonazzi A et al. Identification by site-directed mutagenesis of a hydrophobic binding site of the mitochondrial carnitine/acylcarnitine carrier involved in the interaction with acyl groups. 2012 Biochim. Biophys. Acta pmid:22365929
Arduini A et al. Palmitoyl-L-carnitine, a metabolic intermediate of the fatty acid incorporation pathway in erythrocyte membrane phospholipids. 1990 Biochem. Biophys. Res. Commun. pmid:2256917
pmid:22622056
Satyamoorthy K and Perchellet JP Inhibition of mouse skin tumor promotion by adriamycin and daunomycin in combination with verapamil or palmitoylcarnitine. 1990 Cancer Lett. pmid:2265412
pmid:22678774
Jørgensen W et al. Progression of type 2 diabetes in GK rats affects muscle and liver mitochondria differently: pronounced reduction of complex II flux is observed in liver only. 2012 Am. J. Physiol. Endocrinol. Metab. pmid:22713504
Adams RJ et al. In vitro effects of palmitylcarnitine on cardiac plasma membrane Na,K-ATPase, and sarcoplasmic reticulum Ca2+-ATPase and Ca2+ transport. 1979 J. Biol. Chem. pmid:227894
pmid:2288768
Shi X et al. Lipidomic profiling reveals protective function of fatty acid oxidation in cocaine-induced hepatotoxicity. 2012 J. Lipid Res. pmid:22904346
pmid:2306788
pmid:23224819
pmid:2331016
pmid:23345165
Dixen K et al. ERRγ enhances UCP1 expression and fatty acid oxidation in brown adipocytes. 2013 Obesity (Silver Spring) pmid:23404793
Perevoshchikova IV et al. Sites of superoxide and hydrogen peroxide production during fatty acid oxidation in rat skeletal muscle mitochondria. 2013 Free Radic. Biol. Med. pmid:23583329
Ellis CJ et al. Myoglobinuria: the importance of reaching a firm diagnosis--a patient with defective fatty acid oxidation. 1990 Postgrad Med J pmid:2362895
Moreno-Sánchez R et al. Influence of NAD-linked dehydrogenase activity on flux through oxidative phosphorylation. 1990 Biochem. J. pmid:2363681
Gupte AA et al. High-fat feeding-induced hyperinsulinemia increases cardiac glucose uptake and mitochondrial function despite peripheral insulin resistance. 2013 Endocrinology pmid:23709089
Kanaley JA et al. Hyperinsulinemia and skeletal muscle fatty acid trafficking. 2013 Am. J. Physiol. Endocrinol. Metab. pmid:23820622
O'Hagan DT et al. Nasal absorption enhancers for biosynthetic human growth hormone in rats. 1990 Pharm. Res. pmid:2395807
van Eunen K et al. Biochemical competition makes fatty-acid β-oxidation vulnerable to substrate overload. 2013 PLoS Comput. Biol. pmid:23966849
Hovik R et al. Effects of thia-substituted fatty acids on mitochondrial and peroxisomal beta-oxidation. Studies in vivo and in vitro. 1990 Biochem. J. pmid:2396976
Morand R et al. Quantification of plasma carnitine and acylcarnitines by high-performance liquid chromatography-tandem mass spectrometry using online solid-phase extraction. 2013 Anal Bioanal Chem pmid:23995505
Quinlan CL et al. Sites of reactive oxygen species generation by mitochondria oxidizing different substrates. 2013 Redox Biol pmid:24024165
Voss U et al. Enteric neuropathy can be induced by high fat diet in vivo and palmitic acid exposure in vitro. 2013 PLoS ONE pmid:24312551
Spedding M and Mir AK Direct activation of Ca2+ channels by palmitoyl carnitine, a putative endogenous ligand. 1987 Br. J. Pharmacol. pmid:2445406
Lou PH et al. The mechanism of Intralipid®-mediated cardioprotection complex IV inhibition by the active metabolite, palmitoylcarnitine, generates reactive oxygen species and activates reperfusion injury salvage kinases. 2014 PLoS ONE pmid:24498043
Halle-Smith SC et al. Palmitoyl-CoA inhibits the mitochondrial inner membrane anion-conducting channel. 1988 FEBS Lett. pmid:2456951
Zhang H et al. Metabolomic analysis of biochemical changes in the plasma and urine of collagen-induced arthritis in rats after treatment with Huang-Lian-Jie-Du-Tang. 2014 J Ethnopharmacol pmid:24709313
Patmore L et al. Interaction of palmitoyl carnitine with calcium antagonists in myocytes. 1989 Br. J. Pharmacol. pmid:2474346
Shao Y et al. Lipid metabolites and their differential pro-arrhythmic profiles: of importance in the development of a new anti-arrhythmic pharmacology. 2014 Mol. Cell. Biochem. pmid:24771065
pmid:24780397
pmid:24845952
pmid:24878991
Felser A et al. Hepatic toxicity of dronedarone in mice: role of mitochondrial β-oxidation. 2014 Toxicology pmid:24881592
pmid:2510729
Veitch K et al. Inhibition of mitochondrial beta-oxidation and peroxisomal stimulation in rodent livers by valproate. 1989 Biochem. Soc. Trans. pmid:2516819
pmid:2540838
pmid:2554984
Roussel J et al. Palmitoyl-carnitine increases RyR2 oxidation and sarcoplasmic reticulum Ca2+ leak in cardiomyocytes: Role of adenine nucleotide translocase. 2015 Biochim. Biophys. Acta pmid:25619687
Akerström B and Landin B Rat alpha 1-microglobulin. Purification from urine and synthesis by hepatocyte monolayers. 1985 Eur. J. Biochem. pmid:2578392
Bussolino F et al. Platelet-activating factor enhances complement-dependent phagocytosis of diamide-treated erythrocytes by human monocytes through activation of protein kinase C and phosphorylation of complement receptor type one (CR1). 1989 J. Biol. Chem. pmid:2600088
Schooneman MG et al. Transorgan fluxes in a porcine model reveal a central role for liver in acylcarnitine metabolism. 2015 Am. J. Physiol. Endocrinol. Metab. pmid:26037250
Gualberto A and Saggerson ED Differentiation of rapid and slower-acting effects of insulin on mitochondrial processes in brown adipose tissue from streptozotocin-diabetic rats. 1989 Biochem. J. pmid:2649091
Cavar M et al. Trimetazidine does not alter metabolic substrate oxidation in cardiac mitochondria of target patient population. 2016 Br. J. Pharmacol. pmid:26844527
Ojuka E et al. Measurement of β-oxidation capacity of biological samples by respirometry: a review of principles and substrates. 2016 Am. J. Physiol. Endocrinol. Metab. pmid:26908505
Vorkas PA et al. Metabolic Phenotypes of Carotid Atherosclerotic Plaques Relate to Stroke Risk: An Exploratory Study. 2016 Eur J Vasc Endovasc Surg pmid:27231199
Brass EP Metabolism of octanoyl- and palmitoylcarnitine by intact rat hepatocytes. 1989 Biochim. Biophys. Acta pmid:2730893