Propionylcarnitine

Propionylcarnitine is a lipid of Fatty Acyls (FA) class. Propionylcarnitine is associated with abnormalities such as Failure to Thrive. The involved functions are known as Functional disorder. Propionylcarnitine often locates in Body tissue.

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Introduction

To understand associated biological information of Propionylcarnitine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Propionylcarnitine?

Propionylcarnitine is suspected in Failure to Thrive and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Propionylcarnitine

MeSH term MeSH ID Detail
Penile Induration D010411 4 associated lipids
Amino Acid Metabolism, Inborn Errors D000592 16 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Pregnancy Complications D011248 19 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Starvation D013217 47 associated lipids
Reperfusion Injury D015427 65 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Body Weight D001835 333 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with Propionylcarnitine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Propionylcarnitine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Propionylcarnitine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

What genes are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Propionylcarnitine

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Brass EP et al. Carnitine delays rat skeletal muscle fatigue in vitro. 1993 J. Appl. Physiol. pmid:8282608
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Mancinelli R L-propionylcarnitine and synchronization of spontaneous activity in rat isolated portal vein. 1993 Arch Ital Biol pmid:8338391
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Micheletti R et al. Propionyl-L-carnitine limits chronic ventricular dilation after myocardial infarction in rats. 1993 Am. J. Physiol. pmid:8476087
Duncker DJ et al. L-propionylcarnitine does not affect myocardial metabolic or functional response to chronotropic and inotropic stimulation after repetitive ischemia in anesthetized pigs. 1993 J. Cardiovasc. Pharmacol. pmid:7504143
Minkler PE and Hoppel CL Quantification of free carnitine, individual short- and medium-chain acylcarnitines, and total carnitine in plasma by high-performance liquid chromatography. 1993 Anal. Biochem. pmid:8214594
Di Lisa F et al. Contrasting effects of propionate and propionyl-L-carnitine on energy-linked processes in ischemic hearts. 1994 Am. J. Physiol. pmid:8067396
Micheletti R et al. Propionyl-L-carnitine prevents myocardial mechanical alterations due to pressure overload in rats. 1994 Am. J. Physiol. pmid:8023981
Bartels GL et al. Effects of L-propionylcarnitine on ischemia-induced myocardial dysfunction in men with angina pectoris. 1994 Am. J. Cardiol. pmid:8023775
De Maria P et al. Effect of the addition of electrolytes on the partition coefficients, activity coefficients, and acid dissociation constants of carnitine and its acetyl and propionyl derivatives. 1994 J Pharm Sci pmid:8071833
Tassani V et al. Anaplerotic effect of propionyl carnitine in rat heart mitochondria. 1994 Biochem. Biophys. Res. Commun. pmid:8135845
Reggiani C et al. Effect of propionyl-L-carnitine (PLC) on the kinetic properties of the myofibrillar system in pressure overload cardiac hypertrophy. 1995 Ann. N. Y. Acad. Sci. pmid:7755261
Maresca P et al. Propionyl-L-carnitine improves mechanical performance of papillary muscle from dilated cardiomyopathic hamsters. 1995 Ann. N. Y. Acad. Sci. pmid:7755262
Li P et al. Myocyte performance during evolution of myocardial infarction in rats: effects of propionyl-L-carnitine. 1995 Am. J. Physiol. pmid:7733374
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Micheletti R et al. Effect of propionyl-l-carnitine and enalapril on cardiac function of pressure-overloaded rats during increase in load. 1995 Eur. J. Pharmacol. pmid:8605951
Davenport RJ et al. Propionyl-L-carnitine: labelling in the N-methyl position with carbon-11 and pharmacokinetic studies in rats. 1995 Nucl. Med. Biol. pmid:8535330
Odiet JA et al. Carnitine palmitoyl transferase-I activity in the aging mouse heart. 1995 Mech. Ageing Dev. pmid:7616763
Schönekess BO et al. Propionyl L-carnitine improvement of hypertrophied heart function is accompanied by an increase in carbohydrate oxidation. 1995 Circ. Res. pmid:7554119
Corsi C et al. L-propionylcarnitine effect on postexercise and postischemic hyperemia in patients affected by peripheral vascular disease. 1995 Angiology pmid:7639417
Brevetti G et al. Propionyl-L-carnitine in intermittent claudication: double-blind, placebo-controlled, dose titration, multicenter study. 1995 J. Am. Coll. Cardiol. pmid:7594063
Spagnoli LG et al. Propionyl-L-carnitine prevents the progression of atherosclerotic lesions in aged hyperlipemic rabbits. 1995 Atherosclerosis pmid:7605374
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Cunningham VJ et al. Uptake of [N-methyl-11C]propionyl-L-carnitine (PLC) in human myocardium. 1996 J. Pharmacol. Exp. Ther. pmid:8613961
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Mauriello A et al. Effect of long-term treatment with propionyl-L-carnitine on smooth muscle cell polyploidy in spontaneously hypertensive rats. 1996 Hypertension pmid:8707378
Broderick TL et al. L-propionylcarnitine enhancement of substrate oxidation and mitochondrial respiration in the diabetic rat heart. 1996 J. Mol. Cell. Cardiol. pmid:8729065
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