Propionylcarnitine

Propionylcarnitine is a lipid of Fatty Acyls (FA) class. Propionylcarnitine is associated with abnormalities such as Failure to Thrive. The involved functions are known as Functional disorder. Propionylcarnitine often locates in Body tissue.

Cross Reference

Introduction

To understand associated biological information of Propionylcarnitine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Propionylcarnitine?

Propionylcarnitine is suspected in Failure to Thrive and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Propionylcarnitine

MeSH term MeSH ID Detail
Penile Induration D010411 4 associated lipids
Amino Acid Metabolism, Inborn Errors D000592 16 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Pregnancy Complications D011248 19 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Starvation D013217 47 associated lipids
Reperfusion Injury D015427 65 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Body Weight D001835 333 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with Propionylcarnitine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Propionylcarnitine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Propionylcarnitine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

What genes are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Propionylcarnitine

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Authors Title Published Journal PubMed Link
Brass EP et al. Effect of carnitine acetyltransferase inhibition on rat hepatocyte metabolism. 1991 Biochim. Biophys. Acta pmid:1932127
Vargiu R et al. Positive inotropic effect of coenzyme Q10, omega-3 fatty acids and propionyl-L-carnitine on papillary muscle force-frequency responses of BIO TO-2 cardiomyopathic Syrian hamsters. 2008 Biofactors pmid:19096109
Vargiu R et al. Enhancement of shortening velocity, power, and acto-myosin crossbridge (CB) kinetics following long-term treatment with propionyl-L-carnitine, coenzyme Q10, and omega-3 fatty acids in BIO TO-2 cardiomyopathic Syrian hamsters papillary muscle. 2010 May-Jun Biofactors pmid:20533397
Origlia N et al. Protective effect of L-propionylcarnitine in chronic cyclosporine-a induced nephrotoxicity. 2006 Biomed. Pharmacother. pmid:16472963
Cavallini G et al. Oral propionyl-l-carnitine and intraplaque verapamil in the therapy of advanced and resistant Peyronie's disease. 2002 BJU Int. pmid:12010235
Pace S et al. Pharmacokinetics of propionyl-L-carnitine in humans: evidence for saturable tubular reabsorption. 2000 Br J Clin Pharmacol pmid:11069438
Mingorance C et al. Oral supplementation of propionyl-l-carnitine reduces body weight and hyperinsulinaemia in obese Zucker rats. 2009 Br. J. Nutr. pmid:19545458
Elliott GR et al. The effect of acute feeding of carnitine, acetyl carnitine and propionyl carnitine on basal and A23187-stimulated eicosanoid release from rat carrageenan-elicited peritoneal macrophages. 1990 Br. J. Nutr. pmid:2171633
Barbieri M et al. Lack of correlation between the antiarrhythmic effect of L-propionylcarnitine on reoxygenation-induced arrhythmias and its electrophysiological properties. 1991 Br. J. Pharmacol. pmid:2043933
Laviano A et al. Carnitine administration reduces cytokine levels, improves food intake, and ameliorates body composition in tumor-bearing rats. 2011 Cancer Invest. pmid:22085273
Huang Q et al. Metabolic characterization of hepatocellular carcinoma using nontargeted tissue metabolomics. 2013 Cancer Res. pmid:23824744
Koh SG et al. Exercise intolerance during post-MI heart failure in rats: prevention with supplemental dietary propionyl-L-carnitine. 2003 Cardiovasc Drugs Ther pmid:12843682
Milio G et al. Pharmacological treatment of patients with chronic critical limb ischemia: L-propionyl-carnitine enhances the short-term effects of PGE-1. 2009 Cardiovasc Drugs Ther pmid:19548076
Lango R et al. Propionyl-L-carnitine improves hemodynamics and metabolic markers of cardiac perfusion during coronary surgery in diabetic patients. 2005 Cardiovasc Drugs Ther pmid:16187006
De Marchi S et al. Propionyl-L-carnitine improves endothelial function, microcirculation and pain management in critical limb ischemia. 2012 Cardiovasc Drugs Ther pmid:22936457
Vanella A et al. L -propionyl-carnitine as superoxide scavenger, antioxidant, and DNA cleavage protector. 2000 Cell Biol. Toxicol. pmid:10917565
Zhang Y et al. Prenatal diagnosis of methylmalonic aciduria by analysis of organic acids and total homocysteine in amniotic fluid. 2008 Chin. Med. J. pmid:18298912
Schönekess BO et al. Propionyl L-carnitine improvement of hypertrophied heart function is accompanied by an increase in carbohydrate oxidation. 1995 Circ. Res. pmid:7554119
Brevetti G et al. Muscle carnitine deficiency in patients with severe peripheral vascular disease. 1991 Circulation pmid:1914091
Montisci R et al. Effect of a single IV administration of L-propionylcarnitine on myocardial microcirculation assessed by coronary flow velocity reserve measurement in patients with systemic sclerosis: a pilot study. 2007 Clin Ther pmid:17379056