Propionylcarnitine

Propionylcarnitine is a lipid of Fatty Acyls (FA) class. Propionylcarnitine is associated with abnormalities such as Failure to Thrive. The involved functions are known as Functional disorder. Propionylcarnitine often locates in Body tissue.

Cross Reference

Introduction

To understand associated biological information of Propionylcarnitine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Propionylcarnitine?

Propionylcarnitine is suspected in Failure to Thrive and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Propionylcarnitine

MeSH term MeSH ID Detail
Penile Induration D010411 4 associated lipids
Amino Acid Metabolism, Inborn Errors D000592 16 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Pregnancy Complications D011248 19 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Starvation D013217 47 associated lipids
Reperfusion Injury D015427 65 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Body Weight D001835 333 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with Propionylcarnitine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Propionylcarnitine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Propionylcarnitine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

What genes are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Propionylcarnitine

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Authors Title Published Journal PubMed Link
Cunningham VJ et al. Uptake of [N-methyl-11C]propionyl-L-carnitine (PLC) in human myocardium. 1996 J. Pharmacol. Exp. Ther. pmid:8613961
Hotta N et al. Effect of propionyl-L-carnitine on motor nerve conduction, autonomic cardiac function, and nerve blood flow in rats with streptozotocin-induced diabetes: comparison with an aldose reductase inhibitor. 1996 J. Pharmacol. Exp. Ther. pmid:8558455
Marble M et al. Neonatal vitamin B12 deficiency secondary to maternal subclinical pernicious anemia: identification by expanded newborn screening. 2008 J. Pediatr. pmid:18410783
Bogusiewicz A et al. In HepG2 cells, coexisting carnitine deficiency masks important indicators of marginal biotin deficiency. 2015 J. Nutr. pmid:25527659
Brass EP and Ruff LJ Effect of carnitine on propionate metabolism in the vitamin B-12--deficient rat. 1989 J. Nutr. pmid:2778544
Perna AF et al. L-Propionyl carnitine, homocysteine and S-adenosylhomocysteine in hemodialysis. 2007 Jan-Feb J. Nephrol. pmid:17347975
Broderick TL et al. L-propionylcarnitine enhancement of substrate oxidation and mitochondrial respiration in the diabetic rat heart. 1996 J. Mol. Cell. Cardiol. pmid:8729065
Kotaka K et al. Reversal of ischemia-induced mitochondrial dysfunction after coronary reperfusion. 1982 J. Mol. Cell. Cardiol. pmid:7108975
Ferrari R et al. Prolonged propionyl-L-carnitine pre-treatment of rabbit: biochemical, hemodynamic and electrophysiological effects on myocardium. 1992 J. Mol. Cell. Cardiol. pmid:1625347
Huemer M et al. Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines. 2015 J. Inherit. Metab. Dis. pmid:25762406
Shigematsu Y et al. Useful second-tier tests in expanded newborn screening of isovaleric acidemia and methylmalonic aciduria. 2010 J. Inherit. Metab. Dis. pmid:20440648
Kuster T et al. Filter paper cards contaminated with EMLA cream produce artefacts on acylcarnitine analysis. 2004 J. Inherit. Metab. Dis. pmid:15669691
Kuhara T et al. Gas chromatographic-mass spectrometric newborn screening for propionic acidaemia by targeting methylcitrate in dried filter-paper urine samples. 2002 J. Inherit. Metab. Dis. pmid:12118533
Wang F et al. Clinical, biochemical, and molecular analysis of combined methylmalonic acidemia and hyperhomocysteinemia (cblC type) in China. 2010 J. Inherit. Metab. Dis. pmid:20924684
Hailemariam D et al. Identification of predictive biomarkers of disease state in transition dairy cows. 2014 J. Dairy Sci. pmid:24630653
Roe CR et al. L-carnitine enhances excretion of propionyl coenzyme A as propionylcarnitine in propionic acidemia. 1984 J. Clin. Invest. pmid:6725560
Hasegawa Y et al. Prenatal diagnosis for organic acid disorders using two mass spectrometric methods, gas chromatography mass spectrometry and tandem mass spectrometry. 2005 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:15908288
Delgado C et al. Subacute presentation of propionic acidemia. 2007 J. Child Neurol. pmid:18174561
Duncker DJ et al. L-propionylcarnitine does not affect myocardial metabolic or functional response to chronotropic and inotropic stimulation after repetitive ischemia in anesthetized pigs. 1993 J. Cardiovasc. Pharmacol. pmid:7504143
Aomine M et al. Electrophysiologic effects of a short-chain acyl carnitine, L-propionylcarnitine, on isolated canine Purkinje fibers. 1989 J. Cardiovasc. Pharmacol. pmid:2471897