|
|
|
|
pmid:
|
| Cipolla MJ et al. |
Propionyl-L-carnitine dilates human subcutaneous arteries through an endothelium-dependent mechanism. |
1999 |
J. Vasc. Surg. |
pmid:10359944
|
| Wu X et al. |
Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter. |
1999 |
J. Pharmacol. Exp. Ther. |
pmid:10454528
|
| Triggiani M et al. |
Inhibition of platelet-activating factor synthesis in human neutrophils and platelets by propionyl-L-carnitine. |
1999 |
Biochem. Pharmacol. |
pmid:10487538
|
| Brevetti G et al. |
European multicenter study on propionyl-L-carnitine in intermittent claudication. |
1999 |
J. Am. Coll. Cardiol. |
pmid:10551714
|
| Löster H et al. |
Effects of L-carnitine and its acetyl and propionyl esters on ATP and PCr levels of isolated rat hearts perfused without fatty acids and investigated by means of 31P-NMR spectroscopy. |
1999 |
Mol. Cell. Biochem. |
pmid:10569188
|
| Palmieri L et al. |
Identification of the mitochondrial carnitine carrier in Saccharomyces cerevisiae. |
1999 |
FEBS Lett. |
pmid:10622748
|
| Sayed-Ahmed MM et al. |
Propionyl-L-carnitine as potential protective agent against adriamycin-induced impairment of fatty acid beta-oxidation in isolated heart mitochondria. |
2000 |
Pharmacol. Res. |
pmid:10623482
|
| Ganapathy ME et al. |
beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter. |
2000 |
J. Biol. Chem. |
pmid:10636865
|
| Roe DS et al. |
Evidence for a short-chain carnitine-acylcarnitine translocase in mitochondria specifically related to the metabolism of branched-chain amino acids. |
2000 |
Mol. Genet. Metab. |
pmid:10655160
|
| Libert R et al. |
Identification of undescribed medium-chain acylcarnitines present in urine of patients with propionic and methylmalonic acidemias. |
2000 |
Clin. Chim. Acta |
pmid:10767396
|
| Broderick TL et al. |
Propionyl-L-carnitine effects on postischemic recovery of heart function and substrate oxidation in the diabetic rat. |
2000 |
Mol. Cell. Biochem. |
pmid:10839205
|
| Vanella A et al. |
L -propionyl-carnitine as superoxide scavenger, antioxidant, and DNA cleavage protector. |
2000 |
Cell Biol. Toxicol. |
pmid:10917565
|
| Pace S et al. |
Pharmacokinetics of propionyl-L-carnitine in humans: evidence for saturable tubular reabsorption. |
2000 |
Br J Clin Pharmacol |
pmid:11069438
|
| Mancinelli A et al. |
Disposition of L-carnitine and its short-chain esters, acetyl-L-carnitine and propionyl-L-carnitine, in the rat isolated perfused liver. |
2000 |
Drug Metab. Dispos. |
pmid:11095575
|
| Felix C et al. |
Effects of propionyl-L-carnitine on isolated mitochondrial function in the reperfused diabetic rat heart. |
2001 |
Diabetes Res. Clin. Pract. |
pmid:11378209
|
| Hiatt WR et al. |
Propionyl-L-carnitine improves exercise performance and functional status in patients with claudication. |
2001 |
Am. J. Med. |
pmid:11382369
|
| Sayed-Ahmed MM et al. |
Propionyl-L-carnitine as protector against adriamycin-induced cardiomyopathy. |
2001 |
Pharmacol. Res. |
pmid:11419959
|
| Giancaterini A et al. |
Effects of propyonil-l-carnitine topical irrigation in distal ulcerative colitis: a preliminary report. |
2001 |
Am. J. Gastroenterol. |
pmid:11467678
|
| Barker GA et al. |
Effect of propionyl-L-carnitine on exercise performance in peripheral arterial disease. |
2001 |
Med Sci Sports Exerc |
pmid:11528327
|
| Signorelli SS et al. |
Effects of ischaemic stress on leukocyte activation processes in patients with chronic peripheral occlusive arterial disease: role of L-propionyl carnitine administration. |
2001 |
Pharmacol. Res. |
pmid:11592865
|
| Chace DH et al. |
Rapid diagnosis of methylmalonic and propionic acidemias: quantitative tandem mass spectrometric analysis of propionylcarnitine in filter-paper blood specimens obtained from newborns. |
2001 |
Clin. Chem. |
pmid:11673377
|
| Orlandi A et al. |
Propionyl-L-carnitine reduces intimal hyperplasia after injury in normocholesterolemic rabbit carotid artery by modulating proliferation and caspase 3-dependent apoptosis of vascular smooth muscle cells. |
2002 |
Atherosclerosis |
pmid:11755925
|
| Doggrell SA |
Pharmacotherapy of intermittent claudication. |
2001 |
Expert Opin Pharmacother |
pmid:11825312
|
| Mister M et al. |
Propionyl-L-carnitine prevents renal function deterioration due to ischemia/reperfusion. |
2002 |
Kidney Int. |
pmid:11849462
|
| Cavallini G et al. |
Oral propionyl-l-carnitine and intraplaque verapamil in the therapy of advanced and resistant Peyronie's disease. |
2002 |
BJU Int. |
pmid:12010235
|
| Vargiu R et al. |
Enhancement of muscular performance by a coformulation of propionyl-L-carnitine, coenzyme Q10, nicotinamide, riboflavin and pantothenic acid in the rat. |
2002 |
Physiol. Behav. |
pmid:12044598
|
| Kushnir MM et al. |
Serum acylcarnitines and vitamin B12 deficiency. |
2002 |
Clin. Chem. |
pmid:12089192
|
| Kuhara T et al. |
Gas chromatographic-mass spectrometric newborn screening for propionic acidaemia by targeting methylcitrate in dried filter-paper urine samples. |
2002 |
J. Inherit. Metab. Dis. |
pmid:12118533
|
| Yorifuji T et al. |
Unexpectedly high prevalence of the mild form of propionic acidemia in Japan: presence of a common mutation and possible clinical implications. |
2002 |
Hum. Genet. |
pmid:12189489
|
| Ferrari R et al. |
Metabolic modulation and optimization of energy consumption in heart failure. |
2003 |
Med. Clin. North Am. |
pmid:12693736
|
| Koh SG et al. |
Exercise intolerance during post-MI heart failure in rats: prevention with supplemental dietary propionyl-L-carnitine. |
2003 |
Cardiovasc Drugs Ther |
pmid:12843682
|
| Arafa HM and Sayed-Ahmed MM |
Protective role of carnitine esters against alcohol-induced gastric lesions in rats. |
2003 |
Pharmacol. Res. |
pmid:12860448
|
| Reznick AZ et al. |
Antiradical effects in L-propionyl carnitine protection of the heart against ischemia-reperfusion injury: the possible role of iron chelation. |
1992 |
Arch. Biochem. Biophys. |
pmid:1321584
|
| Bartels GL et al. |
Acute improvement of cardiac function with intravenous L-propionylcarnitine in humans. |
1992 |
J. Cardiovasc. Pharmacol. |
pmid:1383625
|
| Yang XP et al. |
Hemodynamic and metabolic activities of propionyl-L-carnitine in rats with pressure-overload cardiac hypertrophy. |
1992 |
J. Cardiovasc. Pharmacol. |
pmid:1383636
|
| Cui J et al. |
Effects of L-carnitine and its derivatives on postischemic cardiac function, ventricular fibrillation and necrotic and apoptotic cardiomyocyte death in isolated rat hearts. |
2003 |
Mol. Cell. Biochem. |
pmid:14674702
|
| Motterlini R et al. |
Functional and metabolic effects of propionyl-L-carnitine in the isolated perfused hypertrophied rat heart. |
1992 |
Mol. Cell. Biochem. |
pmid:1480142
|
| Sakuma T et al. |
The urinary acylcarnitine profile in three cases of transient hyperammonemia of the newborn. |
1992 |
Acta Paediatr. |
pmid:1498512
|
| Vermeulen RC and Scholte HR |
Exploratory open label, randomized study of acetyl- and propionylcarnitine in chronic fatigue syndrome. |
2004 Mar-Apr |
Psychosom Med |
pmid:15039515
|
| Sethi R et al. |
Improvement of cardiac function and beta-adrenergic signal transduction by propionyl L-carnitine in congestive heart failure due to myocardial infarction. |
2004 |
Coron. Artery Dis. |
pmid:15201623
|
| Ragozzino G et al. |
Effects of propionyl-carnitine in patients with type 2 diabetes and peripheral vascular disease: results of a pilot trial. |
2004 |
Drugs R D |
pmid:15230623
|
| Broderick TL et al. |
Effects of propionyl-carnitine on mitochondrial respiration and post-ischaemic cardiac function in the ischaemic underperfused diabetic rat heart. |
2004 |
Drugs R D |
pmid:15230624
|
| Gentile V et al. |
Preliminary observations on the use of propionyl-L-carnitine in combination with sildenafil in patients with erectile dysfunction and diabetes. |
2004 |
Curr Med Res Opin |
pmid:15383186
|
| Ferrari R et al. |
Therapeutic effects of L-carnitine and propionyl-L-carnitine on cardiovascular diseases: a review. |
2004 |
Ann. N. Y. Acad. Sci. |
pmid:15591005
|
| Hiatt WR |
Carnitine and peripheral arterial disease. |
2004 |
Ann. N. Y. Acad. Sci. |
pmid:15591006
|
| D'Acquarica I et al. |
Enantio- and chemo-selective HPLC separations by chiral-achiral tandem-columns approach: the combination of CHIROBIOTIC TAG and SCX columns for the analysis of propionyl carnitine and related impurities. |
2004 |
J Chromatogr A |
pmid:15641359
|
| Kuster T et al. |
Filter paper cards contaminated with EMLA cream produce artefacts on acylcarnitine analysis. |
2004 |
J. Inherit. Metab. Dis. |
pmid:15669691
|
| Hasegawa Y et al. |
Prenatal diagnosis for organic acid disorders using two mass spectrometric methods, gas chromatography mass spectrometry and tandem mass spectrometry. |
2005 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:15908288
|
| Mancinelli A et al. |
Uptake of L-carnitine and its short-chain ester propionyl-L-carnitine in the isolated perfused rat liver. |
2005 |
J. Pharmacol. Exp. Ther. |
pmid:15951397
|
| Bueno R et al. |
L-carnitine and propionyl-L-carnitine improve endothelial dysfunction in spontaneously hypertensive rats: different participation of NO and COX-products. |
2005 |
Life Sci. |
pmid:15958269
|
| Lango R et al. |
Propionyl-L-carnitine improves hemodynamics and metabolic markers of cardiac perfusion during coronary surgery in diabetic patients. |
2005 |
Cardiovasc Drugs Ther |
pmid:16187006
|
| Ferrari R et al. |
Prolonged propionyl-L-carnitine pre-treatment of rabbit: biochemical, hemodynamic and electrophysiological effects on myocardium. |
1992 |
J. Mol. Cell. Cardiol. |
pmid:1625347
|
| Gómez-Amores L et al. |
Antioxidant activity of propionyl-L-carnitine in liver and heart of spontaneously hypertensive rats. |
2006 |
Life Sci. |
pmid:16263137
|
| Cavallini G et al. |
Acetyl-L-carnitine plus propionyl-L-carnitine improve efficacy of sildenafil in treatment of erectile dysfunction after bilateral nerve-sparing radical retropubic prostatectomy. |
2005 |
Urology |
pmid:16286128
|
| Kendler BS |
Supplemental conditionally essential nutrients in cardiovascular disease therapy. |
2006 Jan-Feb |
J Cardiovasc Nurs |
pmid:16407731
|
| Al-Majed AA et al. |
Propionyl-L-carnitine prevents the progression of cisplatin-induced cardiomyopathy in a carnitine-depleted rat model. |
2006 |
Pharmacol. Res. |
pmid:16436331
|
| Bene J et al. |
Changes of plasma fasting carnitine ester profile in patients with ulcerative colitis. |
2006 |
World J. Gastroenterol. |
pmid:16440427
|
| Santo SS et al. |
Effect of PLC on functional parameters and oxidative profile in type 2 diabetes-associated PAD. |
2006 |
Diabetes Res. Clin. Pract. |
pmid:16446007
|
| Campbell CD et al. |
Two newborns with nutritional vitamin B12 deficiency: challenges in newborn screening for vitamin B12 deficiency. |
2005 |
Haematologica |
pmid:16464760
|
| Origlia N et al. |
Protective effect of L-propionylcarnitine in chronic cyclosporine-a induced nephrotoxicity. |
2006 |
Biomed. Pharmacother. |
pmid:16472963
|
| Silvestro A et al. |
Effect of propionylcarnitine on changes in endothelial function and plasma levels of adhesion molecules induced by acute exercise in patients with intermittent claudication. |
2006 Mar-Apr |
Angiology |
pmid:16518521
|
| Packer L et al. |
Free radical scavenging is involved in the protective effect of L-propionyl-carnitine against ischemia-reperfusion injury of the heart. |
1991 |
Arch. Biochem. Biophys. |
pmid:1654837
|
| Signorelli SS et al. |
A randomised, controlled clinical trial evaluating changes in therapeutic efficacy and oxidative parameters after treatment with propionyl L-carnitine in patients with peripheral arterial disease requiring haemodialysis. |
2006 |
Drugs Aging |
pmid:16608381
|
| Signorelli SS et al. |
Propionyl-L-carnitine therapy: effects on endothelin-1 and homocysteine levels in patients with peripheral arterial disease and end-stage renal disease. |
2006 |
Kidney Blood Press. Res. |
pmid:16809937
|
| Al-Majed AA et al. |
Carnitine esters prevent oxidative stress damage and energy depletion following transient forebrain ischaemia in the rat hippocampus. |
2006 |
Clin. Exp. Pharmacol. Physiol. |
pmid:16895547
|
| Loffredo L et al. |
Imbalance between nitric oxide generation and oxidative stress in patients with peripheral arterial disease: effect of an antioxidant treatment. |
2006 |
J. Vasc. Surg. |
pmid:16950429
|
| Orlandi A et al. |
Propionyl-L-carnitine reduces proliferation and potentiates Bax-related apoptosis of aortic intimal smooth muscle cells by modulating nuclear factor-kappaB activity. |
2007 |
J. Biol. Chem. |
pmid:17178728
|
| Al-Majed AA |
Carnitine deficiency provokes cisplatin-induced hepatotoxicity in rats. |
2007 |
Basic Clin. Pharmacol. Toxicol. |
pmid:17309516
|
| Perna AF et al. |
L-Propionyl carnitine, homocysteine and S-adenosylhomocysteine in hemodialysis. |
2007 Jan-Feb |
J. Nephrol. |
pmid:17347975
|
| Lagioia R et al. |
Propionyl-L-carnitine: a new compound in the metabolic approach to the treatment of effort angina. |
1992 |
Int. J. Cardiol. |
pmid:1737667
|
| Montisci R et al. |
Effect of a single IV administration of L-propionylcarnitine on myocardial microcirculation assessed by coronary flow velocity reserve measurement in patients with systemic sclerosis: a pilot study. |
2007 |
Clin Ther |
pmid:17379056
|
| Morano S et al. |
Antioxidant treatment associated with sildenafil reduces monocyte activation and markers of endothelial damage in patients with diabetic erectile dysfunction: a double-blind, placebo-controlled study. |
2007 |
Eur. Urol. |
pmid:17478034
|
| Salonia A |
Editorial comment on: Antioxidant treatment associated with sildenafil reduces monocyte activation and markers of endothelial damage in patients with diabetic erectile dysfunction: a double-blind, placebo-controlled study. |
2007 |
Eur. Urol. |
pmid:17478035
|
| Pickard R |
Editorial comment on: Antioxidant treatment associated with sildenafil reduces monocyte activation and markers of endothelial damage in patients with diabetic erectile dysfunction: a double-blind, placebo-controlled study. |
2007 |
Eur. Urol. |
pmid:17478036
|
| Alvarez de Sotomayor M et al. |
Effect of L-carnitine and propionyl-L-carnitine on endothelial function of small mesenteric arteries from SHR. |
2007 |
J. Vasc. Res. |
pmid:17483601
|
| la Marca G et al. |
Rapid 2nd-tier test for measurement of 3-OH-propionic and methylmalonic acids on dried blood spots: reducing the false-positive rate for propionylcarnitine during expanded newborn screening by liquid chromatography-tandem mass spectrometry. |
2007 |
Clin. Chem. |
pmid:17510301
|
| Leipälä JA et al. |
Protection of the reperfused heart by L-propionylcarnitine. |
1991 |
J. Appl. Physiol. |
pmid:1757378
|
| de Sotomayor MA et al. |
l-carnitine and its propionate: improvement of endothelial function in SHR through superoxide dismutase-dependent mechanisms. |
2007 |
Free Radic. Res. |
pmid:17654045
|
| Orlandi A et al. |
Propionyl-L-carnitine prevents age-related myocardial remodeling in the rabbit. |
2007 |
J. Cardiovasc. Pharmacol. |
pmid:17703133
|
| Safarinejad MR et al. |
Comparison of vitamin E and propionyl-L-carnitine, separately or in combination, in patients with early chronic Peyronie's disease: a double-blind, placebo controlled, randomized study. |
2007 |
J. Urol. |
pmid:17706714
|
| Wikoff WR et al. |
Metabolomics identifies perturbations in human disorders of propionate metabolism. |
2007 |
Clin. Chem. |
pmid:17951291
|
| Aleisa AM et al. |
Reversal of cisplatin-induced carnitine deficiency and energy starvation by propionyl-L-carnitine in rat kidney tissues. |
2007 |
Clin. Exp. Pharmacol. Physiol. |
pmid:17973863
|
| Delgado C et al. |
Subacute presentation of propionic acidemia. |
2007 |
J. Child Neurol. |
pmid:18174561
|
| Broderick TL |
ATP production and TCA activity are stimulated by propionyl-L-carnitine in the diabetic rat heart. |
2008 |
Drugs R D |
pmid:18298127
|
| Zhang Y et al. |
Prenatal diagnosis of methylmalonic aciduria by analysis of organic acids and total homocysteine in amniotic fluid. |
2008 |
Chin. Med. J. |
pmid:18298912
|
| Andreozzi GM et al. |
Levo-propionyl-carnitine improves the effectiveness of supervised physical training on the absolute claudication distance in patients with intermittent claudication. |
2008 Feb-Mar |
Angiology |
pmid:18319227
|
| Marble M et al. |
Neonatal vitamin B12 deficiency secondary to maternal subclinical pernicious anemia: identification by expanded newborn screening. |
2008 |
J. Pediatr. |
pmid:18410783
|
| Allegra C et al. |
Propionyl-L-carnitine in Leriche-Fontaine stage II peripheral arterial obstructive disease. |
2008 Jul-Aug |
Ann Vasc Surg |
pmid:18502605
|
| Sassen LM et al. |
L-propionylcarnitine increases postischemic blood flow but does not affect recovery of energy charge. |
1991 |
Am. J. Physiol. |
pmid:1858918
|
| Sakuma T |
Alteration of urinary carnitine profile induced by benzoate administration. |
1991 |
Arch. Dis. Child. |
pmid:1863104
|
| Chapman KA et al. |
Increased C3-carnitine in a healthy premature infant. |
2008 |
Clin. Chem. |
pmid:18957557
|
| Azzollini N et al. |
Propionyl-L-carnitine prevents early graft dysfunction in allogeneic rat kidney transplantation. |
2008 |
Kidney Int. |
pmid:19008910
|
| Vargiu R et al. |
Positive inotropic effect of coenzyme Q10, omega-3 fatty acids and propionyl-L-carnitine on papillary muscle force-frequency responses of BIO TO-2 cardiomyopathic Syrian hamsters. |
2008 |
Biofactors |
pmid:19096109
|
| Brevetti G et al. |
Muscle carnitine deficiency in patients with severe peripheral vascular disease. |
1991 |
Circulation |
pmid:1914091
|
| Brass EP et al. |
Effect of carnitine acetyltransferase inhibition on rat hepatocyte metabolism. |
1991 |
Biochim. Biophys. Acta |
pmid:1932127
|
| Mingorance C et al. |
Oral supplementation of propionyl-l-carnitine reduces body weight and hyperinsulinaemia in obese Zucker rats. |
2009 |
Br. J. Nutr. |
pmid:19545458
|
| Milio G et al. |
Pharmacological treatment of patients with chronic critical limb ischemia: L-propionyl-carnitine enhances the short-term effects of PGE-1. |
2009 |
Cardiovasc Drugs Ther |
pmid:19548076
|
| Gentile V et al. |
Effect of propionyl-L-carnitine, L-arginine and nicotinic acid on the efficacy of vardenafil in the treatment of erectile dysfunction in diabetes. |
2009 |
Curr Med Res Opin |
pmid:19624286
|
| Chen PW et al. |
Stabilization of blood methylmalonic acid level in methylmalonic acidemia after liver transplantation. |
2010 |
Pediatr Transplant |
pmid:19686300
|
