Propionylcarnitine

Propionylcarnitine is a lipid of Fatty Acyls (FA) class. Propionylcarnitine is associated with abnormalities such as Failure to Thrive. The involved functions are known as Functional disorder. Propionylcarnitine often locates in Body tissue.

Cross Reference

Introduction

To understand associated biological information of Propionylcarnitine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Propionylcarnitine?

Propionylcarnitine is suspected in Failure to Thrive and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Propionylcarnitine

MeSH term MeSH ID Detail
Reperfusion Injury D015427 65 associated lipids
Body Weight D001835 333 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Amino Acid Metabolism, Inborn Errors D000592 16 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Starvation D013217 47 associated lipids
Pregnancy Complications D011248 19 associated lipids
Penile Induration D010411 4 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with Propionylcarnitine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Propionylcarnitine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Propionylcarnitine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

What genes are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Propionylcarnitine

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Authors Title Published Journal PubMed Link
Pekkinen J et al. Betaine supplementation causes increase in carnitine metabolites in the muscle and liver of mice fed a high-fat diet as studied by nontargeted LC-MS metabolomics approach. 2013 Mol Nutr Food Res pmid:23868375
Riccioni C et al. Rehabilitative treatment in peripheral artery disease: protocol application and follow-up. 2010 Minerva Cardioangiol pmid:20948502
Cotter MA et al. Effects of acetyl- and proprionyl-L-carnitine on peripheral nerve function and vascular supply in experimental diabetes. 1995 Metab. Clin. Exp. pmid:7666797
Brass EP and Beyerinck RA Interactions of propionate and carnitine metabolism in isolated rat hepatocytes. 1987 Metab. Clin. Exp. pmid:3110541
Ferrari R et al. Metabolic modulation and optimization of energy consumption in heart failure. 2003 Med. Clin. North Am. pmid:12693736
Barker GA et al. Effect of propionyl-L-carnitine on exercise performance in peripheral arterial disease. 2001 Med Sci Sports Exerc pmid:11528327
Odiet JA et al. Carnitine palmitoyl transferase-I activity in the aging mouse heart. 1995 Mech. Ageing Dev. pmid:7616763
Hozyasz KK et al. Whole blood propionylcarnitine in newborns with orofacial cleft. 2011 Matern Child Nutr pmid:21470367
Gómez-Amores L et al. Antioxidant activity of propionyl-L-carnitine in liver and heart of spontaneously hypertensive rats. 2006 Life Sci. pmid:16263137
Bueno R et al. L-carnitine and propionyl-L-carnitine improve endothelial dysfunction in spontaneously hypertensive rats: different participation of NO and COX-products. 2005 Life Sci. pmid:15958269
Mister M et al. Propionyl-L-carnitine prevents renal function deterioration due to ischemia/reperfusion. 2002 Kidney Int. pmid:11849462
Azzollini N et al. Propionyl-L-carnitine prevents early graft dysfunction in allogeneic rat kidney transplantation. 2008 Kidney Int. pmid:19008910
Signorelli SS et al. Propionyl-L-carnitine therapy: effects on endothelin-1 and homocysteine levels in patients with peripheral arterial disease and end-stage renal disease. 2006 Kidney Blood Press. Res. pmid:16809937
Sarafoglou K et al. Expanded newborn screening for detection of vitamin B12 deficiency. 2011 JAMA pmid:21427371
Cipolla MJ et al. Propionyl-L-carnitine dilates human subcutaneous arteries through an endothelium-dependent mechanism. 1999 J. Vasc. Surg. pmid:10359944
Loffredo L et al. Imbalance between nitric oxide generation and oxidative stress in patients with peripheral arterial disease: effect of an antioxidant treatment. 2006 J. Vasc. Surg. pmid:16950429
Alvarez de Sotomayor M et al. Effect of L-carnitine and propionyl-L-carnitine on endothelial function of small mesenteric arteries from SHR. 2007 J. Vasc. Res. pmid:17483601
Safarinejad MR et al. Comparison of vitamin E and propionyl-L-carnitine, separately or in combination, in patients with early chronic Peyronie's disease: a double-blind, placebo controlled, randomized study. 2007 J. Urol. pmid:17706714
Cunningham VJ et al. Uptake of [N-methyl-11C]propionyl-L-carnitine (PLC) in human myocardium. 1996 J. Pharmacol. Exp. Ther. pmid:8613961
Hotta N et al. Effect of propionyl-L-carnitine on motor nerve conduction, autonomic cardiac function, and nerve blood flow in rats with streptozotocin-induced diabetes: comparison with an aldose reductase inhibitor. 1996 J. Pharmacol. Exp. Ther. pmid:8558455