Propionylcarnitine

Propionylcarnitine is a lipid of Fatty Acyls (FA) class. Propionylcarnitine is associated with abnormalities such as Failure to Thrive. The involved functions are known as Functional disorder. Propionylcarnitine often locates in Body tissue.

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Introduction

To understand associated biological information of Propionylcarnitine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Propionylcarnitine?

Propionylcarnitine is suspected in Failure to Thrive and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Propionylcarnitine

MeSH term MeSH ID Detail
Reperfusion Injury D015427 65 associated lipids
Body Weight D001835 333 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Amino Acid Metabolism, Inborn Errors D000592 16 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Starvation D013217 47 associated lipids
Pregnancy Complications D011248 19 associated lipids
Penile Induration D010411 4 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with Propionylcarnitine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Propionylcarnitine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Propionylcarnitine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

What genes are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Propionylcarnitine

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Authors Title Published Journal PubMed Link
Reggiani C et al. Effect of propionyl-L-carnitine (PLC) on the kinetic properties of the myofibrillar system in pressure overload cardiac hypertrophy. 1995 Ann. N. Y. Acad. Sci. pmid:7755261
Maresca P et al. Propionyl-L-carnitine improves mechanical performance of papillary muscle from dilated cardiomyopathic hamsters. 1995 Ann. N. Y. Acad. Sci. pmid:7755262
Li P et al. Myocyte performance during evolution of myocardial infarction in rats: effects of propionyl-L-carnitine. 1995 Am. J. Physiol. pmid:7733374
Davenport RJ et al. Propionyl-L-carnitine: labelling in the N-methyl position with carbon-11 and pharmacokinetic studies in rats. 1995 Nucl. Med. Biol. pmid:8535330
Odiet JA et al. Carnitine palmitoyl transferase-I activity in the aging mouse heart. 1995 Mech. Ageing Dev. pmid:7616763
Corsi C et al. L-propionylcarnitine effect on postexercise and postischemic hyperemia in patients affected by peripheral vascular disease. 1995 Angiology pmid:7639417
Brevetti G et al. Propionyl-L-carnitine in intermittent claudication: double-blind, placebo-controlled, dose titration, multicenter study. 1995 J. Am. Coll. Cardiol. pmid:7594063
Spagnoli LG et al. Propionyl-L-carnitine prevents the progression of atherosclerotic lesions in aged hyperlipemic rabbits. 1995 Atherosclerosis pmid:7605374
Russell RR et al. Propionyl-L-carnitine-mediated improvement in contractile function of rat hearts oxidizing acetoacetate. 1995 Am. J. Physiol. pmid:7840294
Caruso A et al. Protective effect of propionyl-L-carnitine against PAF-induced rat paw oedema. 1995 Pharmacol. Res. pmid:7784308
Cotter MA et al. Effects of acetyl- and proprionyl-L-carnitine on peripheral nerve function and vascular supply in experimental diabetes. 1995 Metab. Clin. Exp. pmid:7666797
Di Lisa F et al. Contrasting effects of propionate and propionyl-L-carnitine on energy-linked processes in ischemic hearts. 1994 Am. J. Physiol. pmid:8067396
Micheletti R et al. Propionyl-L-carnitine prevents myocardial mechanical alterations due to pressure overload in rats. 1994 Am. J. Physiol. pmid:8023981
Bartels GL et al. Effects of L-propionylcarnitine on ischemia-induced myocardial dysfunction in men with angina pectoris. 1994 Am. J. Cardiol. pmid:8023775
De Maria P et al. Effect of the addition of electrolytes on the partition coefficients, activity coefficients, and acid dissociation constants of carnitine and its acetyl and propionyl derivatives. 1994 J Pharm Sci pmid:8071833
Tassani V et al. Anaplerotic effect of propionyl carnitine in rat heart mitochondria. 1994 Biochem. Biophys. Res. Commun. pmid:8135845
Brass EP et al. Carnitine delays rat skeletal muscle fatigue in vitro. 1993 J. Appl. Physiol. pmid:8282608
Riva E and Leopaldi D Control of the cardiac consequences of myocardial ischemia and reperfusion by L-propionylcarnitine: age-response and dose-response studies in the rat heart. 1993 Pediatr. Res. pmid:8255679
Mancinelli R L-propionylcarnitine and synchronization of spontaneous activity in rat isolated portal vein. 1993 Arch Ital Biol pmid:8338391
Arduini A et al. Effects of L-carnitine and its acetate and propionate esters on the molecular dynamics of human erythrocyte membrane. 1993 Biochim. Biophys. Acta pmid:8383998
Micheletti R et al. Propionyl-L-carnitine limits chronic ventricular dilation after myocardial infarction in rats. 1993 Am. J. Physiol. pmid:8476087
Duncker DJ et al. L-propionylcarnitine does not affect myocardial metabolic or functional response to chronotropic and inotropic stimulation after repetitive ischemia in anesthetized pigs. 1993 J. Cardiovasc. Pharmacol. pmid:7504143
Minkler PE and Hoppel CL Quantification of free carnitine, individual short- and medium-chain acylcarnitines, and total carnitine in plasma by high-performance liquid chromatography. 1993 Anal. Biochem. pmid:8214594
Ferrari R et al. Prolonged propionyl-L-carnitine pre-treatment of rabbit: biochemical, hemodynamic and electrophysiological effects on myocardium. 1992 J. Mol. Cell. Cardiol. pmid:1625347
Lagioia R et al. Propionyl-L-carnitine: a new compound in the metabolic approach to the treatment of effort angina. 1992 Int. J. Cardiol. pmid:1737667
Reznick AZ et al. Antiradical effects in L-propionyl carnitine protection of the heart against ischemia-reperfusion injury: the possible role of iron chelation. 1992 Arch. Biochem. Biophys. pmid:1321584
Sakuma T et al. The urinary acylcarnitine profile in three cases of transient hyperammonemia of the newborn. 1992 Acta Paediatr. pmid:1498512
Motterlini R et al. Functional and metabolic effects of propionyl-L-carnitine in the isolated perfused hypertrophied rat heart. 1992 Mol. Cell. Biochem. pmid:1480142
Bartels GL et al. Acute improvement of cardiac function with intravenous L-propionylcarnitine in humans. 1992 J. Cardiovasc. Pharmacol. pmid:1383625
Yang XP et al. Hemodynamic and metabolic activities of propionyl-L-carnitine in rats with pressure-overload cardiac hypertrophy. 1992 J. Cardiovasc. Pharmacol. pmid:1383636
Brass EP et al. Effect of carnitine acetyltransferase inhibition on rat hepatocyte metabolism. 1991 Biochim. Biophys. Acta pmid:1932127
Di Biase M et al. Electrophysiologic evaluation of intravenous L-propionylcarnitine in man. 1991 Int. J. Cardiol. pmid:2055673
Leipälä JA et al. Protection of the reperfused heart by L-propionylcarnitine. 1991 J. Appl. Physiol. pmid:1757378
Packer L et al. Free radical scavenging is involved in the protective effect of L-propionyl-carnitine against ischemia-reperfusion injury of the heart. 1991 Arch. Biochem. Biophys. pmid:1654837
Brevetti G et al. Muscle carnitine deficiency in patients with severe peripheral vascular disease. 1991 Circulation pmid:1914091
Sassen LM et al. L-propionylcarnitine increases postischemic blood flow but does not affect recovery of energy charge. 1991 Am. J. Physiol. pmid:1858918
Sakuma T Alteration of urinary carnitine profile induced by benzoate administration. 1991 Arch. Dis. Child. pmid:1863104
Barbieri M et al. Lack of correlation between the antiarrhythmic effect of L-propionylcarnitine on reoxygenation-induced arrhythmias and its electrophysiological properties. 1991 Br. J. Pharmacol. pmid:2043933
Marciani P et al. L-carnitine and carnitine ester transport in the rat small intestine. 1991 Pharmacol. Res. pmid:2062791
Pierce GN et al. Na(+)-H+ exchange in cardiac sarcolemmal vesicles isolated from diabetic rats. 1990 Am. J. Physiol. pmid:2154133
Elliott GR et al. The effect of acute feeding of carnitine, acetyl carnitine and propionyl carnitine on basal and A23187-stimulated eicosanoid release from rat carrageenan-elicited peritoneal macrophages. 1990 Br. J. Nutr. pmid:2171633
Aomine M et al. Electrophysiologic effects of a short-chain acyl carnitine, L-propionylcarnitine, on isolated canine Purkinje fibers. 1989 J. Cardiovasc. Pharmacol. pmid:2471897
Brass EP and Ruff LJ Effect of carnitine on propionate metabolism in the vitamin B-12--deficient rat. 1989 J. Nutr. pmid:2778544
Sherry AD et al. Propionate metabolism in the rat heart by 13C n.m.r. spectroscopy. 1988 Biochem. J. pmid:3178775
Brass EP and Stabler SP Carnitine metabolism in the vitamin B-12-deficient rat. 1988 Biochem. J. pmid:3196310
Neri B et al. Differences between carnitine derivatives and coenzyme Q10 in preventing in vitro doxorubicin-related cardiac damages. 1988 Oncology pmid:3368201
Liedtke AJ et al. Effects of L-propionylcarnitine on mechanical recovery during reflow in intact hearts. 1988 Am. J. Physiol. pmid:3394817
Brass EP and Beyerinck RA Interactions of propionate and carnitine metabolism in isolated rat hepatocytes. 1987 Metab. Clin. Exp. pmid:3110541
Cooper TG et al. Characteristics of the transport of carnitine into the cauda epididymidis of the rat as ascertained by luminal perfusion in vitro. 1986 Int. J. Androl. pmid:3570531
Brass EP et al. Inhibition of oxidative metabolism by propionic acid and its reversal by carnitine in isolated rat hepatocytes. 1986 Biochem. J. pmid:3790065