Propionylcarnitine

Propionylcarnitine is a lipid of Fatty Acyls (FA) class. Propionylcarnitine is associated with abnormalities such as Failure to Thrive. The involved functions are known as Functional disorder. Propionylcarnitine often locates in Body tissue.

Cross Reference

Introduction

To understand associated biological information of Propionylcarnitine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Propionylcarnitine?

Propionylcarnitine is suspected in Failure to Thrive and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Propionylcarnitine

MeSH term MeSH ID Detail
Reperfusion Injury D015427 65 associated lipids
Body Weight D001835 333 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Amino Acid Metabolism, Inborn Errors D000592 16 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Starvation D013217 47 associated lipids
Pregnancy Complications D011248 19 associated lipids
Penile Induration D010411 4 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with Propionylcarnitine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Propionylcarnitine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Propionylcarnitine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

What genes are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Propionylcarnitine

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Authors Title Published Journal PubMed Link
Hotta N et al. Effect of propionyl-L-carnitine on motor nerve conduction, autonomic cardiac function, and nerve blood flow in rats with streptozotocin-induced diabetes: comparison with an aldose reductase inhibitor. 1996 J. Pharmacol. Exp. Ther. pmid:8558455
Torielli L et al. Alterations in energy metabolism of hypertrophied rat cardiomyocytes: influence of propionyl-L-carnitine. 1995 J. Cardiovasc. Pharmacol. pmid:8583777
Micheletti R et al. Effect of propionyl-l-carnitine and enalapril on cardiac function of pressure-overloaded rats during increase in load. 1995 Eur. J. Pharmacol. pmid:8605951
Schönekess BO et al. Propionyl L-carnitine improvement of hypertrophied rat heart function is associated with an increase in cardiac efficiency. 1995 Eur. J. Pharmacol. pmid:8605952
Cunningham VJ et al. Uptake of [N-methyl-11C]propionyl-L-carnitine (PLC) in human myocardium. 1996 J. Pharmacol. Exp. Ther. pmid:8613961
Micheletti R et al. Effect of propionyl-L-carnitine on the mechanics of right and left papillary muscles from volume-overloaded rat hearts. 1996 J. Cardiovasc. Pharmacol. pmid:8656658
Mauriello A et al. Effect of long-term treatment with propionyl-L-carnitine on smooth muscle cell polyploidy in spontaneously hypertensive rats. 1996 Hypertension pmid:8707378
Broderick TL et al. L-propionylcarnitine enhancement of substrate oxidation and mitochondrial respiration in the diabetic rat heart. 1996 J. Mol. Cell. Cardiol. pmid:8729065
Hotta N et al. Effect of propionyl-L-carnitine on oscillatory potentials in electroretinogram in streptozotocin-diabetic rats. 1996 Eur. J. Pharmacol. pmid:8891600
Maresca P et al. Positive action of propionyl-L-carnitine on mechanical performance of papillary muscle from Syrian hamsters with hereditary dilated cardiomyopathy. 1995 Eur. J. Pharmacol. pmid:8991805
Palomba D et al. Metabolic and renal effects of Laevo-carnitine and propionyl-carnitine in rats with subtotal nephrectomy. 1996 Sep-Oct Pharmacol. Res. pmid:9051710
Brevetti G et al. Effect of propionyl-L-carnitine on quality of life in intermittent claudication. 1997 Am. J. Cardiol. pmid:9070558
Valoti M et al. Effects of carnitine and its derivatives on gastric acid secretion in rats. 1996 Nov-Dec Pharmacol. Res. pmid:9076846
El Alaoui-Talibi Z et al. Control of oxidative metabolism in volume-overloaded rat hearts: effect of propionyl-L-carnitine. 1997 Am. J. Physiol. pmid:9139943
Serjeant BE et al. Propionyl-L-carnitine in chronic leg ulcers of homozygous sickle cell disease: a pilot study. 1997 J. Am. Acad. Dermatol. pmid:9308570
Ferrari R and De Giuli F The propionyl-L-carnitine hypothesis: an alternative approach to treating heart failure. 1997 J. Card. Fail. pmid:9330130
Davenport RJ et al. Automated chemoenzymatic synthesis of no-carrier-added [carbonyl-11C]propionyl L-carnitine for pharmacokinetic studies. 1997 Appl Radiat Isot pmid:9376826
Stroh R et al. L-propionyl carnitine, an endogenous ester in fatty acid metabolism, exerts anti-shock and endothelial protective effects in rat splanchnic ischemia-reperfusion injury. 1998 Shock pmid:9525330
Wiseman LR and Brogden RN Propionyl-L-carnitine. 1998 Drugs Aging pmid:9534023
Capecchi PL et al. Carnitines increase plasma levels of adenosine and ATP in humans. 1997 Vasc Med pmid:9546959
Taylor DJ et al. Changes in energy metabolism of calf muscle in patients with intermittent claudication assessed by 31P magnetic resonance spectroscopy: a phase II open study. 1996 Vasc Med pmid:9552578
Giovannini L et al. Acute CYA-induced ATP depletion is prevented by pretreatment with L-propionylcarnitine in isolated and perfused rat kidney. 1998 Transplant. Proc. pmid:9723376
Terada R et al. Effects of propionyl-L-carnitine on cardiac dysfunction in streptozotocin-diabetic rats. 1998 Eur. J. Pharmacol. pmid:9797035