Dihydrolipoamide

Dihydrolipoamide is a lipid of Fatty Acyls (FA) class. Dihydrolipoamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Citric Acid Cycle, Electron Transport, NADH oxidation, Oxidation and Oxidants. Dihydrolipoamide often locates in Mitochondria, Mitochondrial matrix and Chloroplasts. The associated genes with Dihydrolipoamide are Mutant Proteins, Recombinant Proteins, mycothione reductase, Genes, Mitochondrial and alanylproline.

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Introduction

To understand associated biological information of Dihydrolipoamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Dihydrolipoamide?

Dihydrolipoamide is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Dihydrolipoamide

MeSH term MeSH ID Detail
Parkinsonian Disorders D020734 20 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Dihydrolipoamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Dihydrolipoamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Dihydrolipoamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Dihydrolipoamide?

There are no associated biomedical information in the current reference collection.

What genes are associated with Dihydrolipoamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Dihydrolipoamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Dihydrolipoamide

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Authors Title Published Journal PubMed Link
Wu YY et al. Proteinase 3 and dihydrolipoamide dehydrogenase (E3) are major autoantigens in hepatitis C virus (HCV) infection. 2002 Clin. Exp. Immunol. pmid:11985526
Cicek G et al. Analysis of mitochondrial antigens reveals inner membrane succinate dehydrogenase flavoprotein subunit as autoantigen to antibodies in anti-M7 sera. 2002 Clin. Exp. Immunol. pmid:11982594
Marie SK and Shinjo SM Metabolism and brain cancer. 2011 Clinics (Sao Paulo) pmid:21779721
Min CK et al. Genome-based construction of the metabolic pathways of Orientia tsutsugamushi and comparative analysis within the Rickettsiales order. 2008 Comp. Funct. Genomics pmid:18528528
Keyes BE and Burke DJ Irc15 Is a microtubule-associated protein that regulates microtubule dynamics in Saccharomyces cerevisiae. 2009 Curr. Biol. pmid:19285398
Brown RM et al. Pyruvate dehydrogenase E3 binding protein (protein X) deficiency. 2006 Dev Med Child Neurol pmid:16904023
Phelps PE et al. Evidence for a cell-specific action of Reelin in the spinal cord. 2002 Dev. Biol. pmid:11900467
Pang S et al. Regulation of fasting fuel metabolism by toll-like receptor 4. 2010 Diabetes pmid:20855545
Yan LJ et al. Histochemical staining and quantification of dihydrolipoamide dehydrogenase diaphorase activity using blue native PAGE. 2007 Electrophoresis pmid:17315258
Kato M et al. A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex. 2006 EMBO J. pmid:17124494
Sawada K et al. Cytosolic cofactors and dihydrolipoamide stimulate hepatic microsomal 5'-deiodination. 1985 Endocrinology pmid:3926468
Goswami A and Rosenberg IN Stimulation of iodothyronine outer ring monodeiodinase by dihydrolipoamide. 1983 Endocrinology pmid:6187559
Hirani TA et al. Asp295 stabilizes the active-site loop structure of pyruvate dehydrogenase, facilitating phosphorylation of ser292 by pyruvate dehydrogenase-kinase. 2011 Enzyme Res pmid:21318135
Mukherjee M et al. Proteins of the glycine decarboxylase complex in the hydrogenosome of Trichomonas vaginalis. 2006 Eukaryotic Cell pmid:17158739
Ono K et al. cDNA cloning of the chicken branched-chain alpha-keto acid dehydrogenase complex. Chicken-specific residues of the acyltransferase affect the overall activity and the interaction with the dehydrogenase. 2001 Eur. J. Biochem. pmid:11168412
Faure M et al. Interaction between the lipoamide-containing H-protein and the lipoamide dehydrogenase (L-protein) of the glycine decarboxylase multienzyme system 2. Crystal structures of H- and L-proteins. 2000 Eur. J. Biochem. pmid:10806386
Bonomi F and Pagani S Removal of ferritin-bound iron by DL-dihydrolipoate and DL-dihydrolipoamide. 1986 Eur. J. Biochem. pmid:3082624
Tozawa K et al. Solution structure of the lipoyl domain of the chimeric dihydrolipoyl dehydrogenase P64K from Neisseria meningitidis. 2001 Eur. J. Biochem. pmid:11559360
Xia L et al. Reduction of ubiquinone by lipoamide dehydrogenase. An antioxidant regenerating pathway. 2001 Eur. J. Biochem. pmid:11231302
Kumar A et al. Redox homeostasis in mycobacteria: the key to tuberculosis control? 2011 Expert Rev Mol Med pmid:22172201