MeSH term | MeSH ID | Detail |
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Parkinsonian Disorders | D020734 | 20 associated lipids |
Dihydrolipoamide is a lipid of Fatty Acyls (FA) class. Dihydrolipoamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Citric Acid Cycle, Electron Transport, NADH oxidation, Oxidation and Oxidants. Dihydrolipoamide often locates in Mitochondria, Mitochondrial matrix and Chloroplasts. The associated genes with Dihydrolipoamide are Mutant Proteins, Recombinant Proteins, mycothione reductase, Genes, Mitochondrial and alanylproline.
To understand associated biological information of Dihydrolipoamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Dihydrolipoamide is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Dihydrolipoamide
MeSH term | MeSH ID | Detail |
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Parkinsonian Disorders | D020734 | 20 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Fujiki Y et al. | Activation of the promoters of Arabidopsis genes for the branched-chain alpha-keto acid dehydrogenase complex in transgenic tobacco BY-2 cells under sugar starvation. | 2002 | Plant Cell Physiol. | pmid:11917081 |
Wu YY et al. | Proteinase 3 and dihydrolipoamide dehydrogenase (E3) are major autoantigens in hepatitis C virus (HCV) infection. | 2002 | Clin. Exp. Immunol. | pmid:11985526 |
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Liu S et al. | Reaction mechanism for mammalian pyruvate dehydrogenase using natural lipoyl domain substrates. | 2001 | Arch. Biochem. Biophys. | pmid:11368334 |
Rezzani R et al. | Does methylene blue protect the kidney tissues from damage induced by ciclosporin A treatment? | 2001 | Nephron | pmid:11598398 |
Fischer A et al. | Effect of selenium and vitamin E deficiency on differential gene expression in rat liver. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11444866 |
Tyler KM et al. | Limitation of Trypanosoma brucei parasitaemia results from density-dependent parasite differentiation and parasite killing by the host immune response. | 2001 | Proc. Biol. Sci. | pmid:11674871 |
Sant'Ana DM et al. | Effects of protein and vitamin B deficiency on blood parameters and myenteric neurons of the colon of rats. | 2001 | Arq Neuropsiquiatr | pmid:11588624 |
Pessach I et al. | Essential requirement of cytosolic phospholipase A(2) for stimulation of NADPH oxidase-associated diaphorase activity in granulocyte-like cells. | 2001 | J. Biol. Chem. | pmid:11432850 |
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Fregonesi CE et al. | Quantitative study of the myenteric plexus of the stomach of rats with streptozotocin-induced diabetes. | 2001 | Arq Neuropsiquiatr | pmid:11299431 |
Katsuki H et al. | Superoxide dismutase activity in organotypic midbrain-striatum co-cultures is associated with resistance of dopaminergic neurons to excitotoxicity. | 2001 | J. Neurochem. | pmid:11238718 |
Piasecka M et al. | Computerized analysis of cytochemical reactions for dehydrogenases and oxygraphic studies as methods to evaluate the function of the mitochondrial sheath in rat spermatozoa. | 2001 | Andrologia | pmid:11167513 |
Korotchkina LG et al. | Protection by thiols of the mitochondrial complexes from 4-hydroxy-2-nonenal. | 2001 | Free Radic. Biol. Med. | pmid:11316579 |
Tozawa K et al. | Solution structure of the lipoyl domain of the chimeric dihydrolipoyl dehydrogenase P64K from Neisseria meningitidis. | 2001 | Eur. J. Biochem. | pmid:11559360 |
Lutziger I and Oliver DJ | Characterization of two cDNAs encoding mitochondrial lipoamide dehydrogenase from Arabidopsis. | 2001 | Plant Physiol. | pmid:11598235 |
Xia L et al. | Reduction of ubiquinone by lipoamide dehydrogenase. An antioxidant regenerating pathway. | 2001 | Eur. J. Biochem. | pmid:11231302 |
Faure M et al. | Interaction between the lipoamide-containing H-protein and the lipoamide dehydrogenase (L-protein) of the glycine decarboxylase multienzyme system 2. Crystal structures of H- and L-proteins. | 2000 | Eur. J. Biochem. | pmid:10806386 |
Self WT et al. | Synthesis and characterization of selenotrisulfide-derivatives of lipoic acid and lipoamide. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11050172 |
Szabados E et al. | Enhanced ADP-ribosylation and its diminution by lipoamide after ischemia-reperfusion in perfused rat heart. | 1999 | Free Radic. Biol. Med. | pmid:10569643 |
Patel MS and Hong YS | Lipoic acid as an antioxidant. The role of dihydrolipoamide dehydrogenase. | 1998 | Methods Mol. Biol. | pmid:9921542 |
Kleemann R et al. | Specific reduction of insulin disulfides by macrophage migration inhibitory factor (MIF) with glutathione and dihydrolipoamide: potential role in cellular redox processes. | 1998 | FEBS Lett. | pmid:9688536 |
Raddatz G and Bisswanger H | Receptor site and stereospecifity of dihydrolipoamide dehydrogenase for R- and S-lipoamide: a molecular modeling study. | 1997 | J. Biotechnol. | pmid:9383983 |
Allen MD and Perham RN | The catalytic domain of dihydrolipoyl acetyltransferase from the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus. Expression, purification and reversible denaturation. | 1997 | FEBS Lett. | pmid:9280309 |
Molina Portela MP and Stoppani AO | Redox cycling of beta-lapachone and related o-naphthoquinones in the presence of dihydrolipoamide and oxygen. | 1996 | Biochem. Pharmacol. | pmid:8573194 |
Patel MS et al. | Dihydrolipoamide dehydrogenase: activity assays. | 1995 | Meth. Enzymol. | pmid:7476353 |
Anusevicius ZJ and Cènas NK | Dihydrolipoamide-mediated redox cycling of quinones. | 1993 | Arch. Biochem. Biophys. | pmid:8387746 |
Fairlamb AH et al. | The interaction of arsenical drugs with dihydrolipoamide and dihydrolipoamide dehydrogenase from arsenical resistant and sensitive strains of Trypanosoma brucei brucei. | 1992 | Mol. Biochem. Parasitol. | pmid:1501642 |
Sahlman L and Williams CH | Lipoamide dehydrogenase from Escherichia coli. Steady-state kinetics of the physiological reaction. | 1989 | J. Biol. Chem. | pmid:2498307 |
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Rahmatullah M and Roche TE | Component requirements for NADH inhibition and spermine stimulation of pyruvate dehydrogenaseb phosphatase activity. | 1988 | J. Biol. Chem. | pmid:2836411 |
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Bonomi F and Pagani S | Removal of ferritin-bound iron by DL-dihydrolipoate and DL-dihydrolipoamide. | 1986 | Eur. J. Biochem. | pmid:3082624 |
Sawada K et al. | Cytosolic cofactors and dihydrolipoamide stimulate hepatic microsomal 5'-deiodination. | 1985 | Endocrinology | pmid:3926468 |
Goswami A and Rosenberg IN | Iodothyronine 5'-deiodinase in rat kidney microsomes. Kinetic behavior at low substrate concentrations. | 1984 | J. Clin. Invest. | pmid:6439742 |
Goswami A and Rosenberg IN | Stimulation of iodothyronine outer ring monodeiodinase by dihydrolipoamide. | 1983 | Endocrinology | pmid:6187559 |
Becker DM et al. | Optimal conditions for the assay of lipoamide dehydrogenase in homogenized human platelets. | 1982 | Clin. Chim. Acta | pmid:6805984 |
O'Connor TP et al. | 13C nuclear magnetic resonance study of the pyruvate dehydrogenase-catalyzed acetylation of dihydrolipoamide. | 1982 | J. Biol. Chem. | pmid:6801041 |
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