MeSH term | MeSH ID | Detail |
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Parkinsonian Disorders | D020734 | 20 associated lipids |
Dihydrolipoamide is a lipid of Fatty Acyls (FA) class. Dihydrolipoamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Citric Acid Cycle, Electron Transport, NADH oxidation, Oxidation and Oxidants. Dihydrolipoamide often locates in Mitochondria, Mitochondrial matrix and Chloroplasts. The associated genes with Dihydrolipoamide are Mutant Proteins, Recombinant Proteins, mycothione reductase, Genes, Mitochondrial and alanylproline.
To understand associated biological information of Dihydrolipoamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Dihydrolipoamide is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Dihydrolipoamide
MeSH term | MeSH ID | Detail |
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Parkinsonian Disorders | D020734 | 20 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Bonomi F and Pagani S | Removal of ferritin-bound iron by DL-dihydrolipoate and DL-dihydrolipoamide. | 1986 | Eur. J. Biochem. | pmid:3082624 |
Mukherjee M et al. | Proteins of the glycine decarboxylase complex in the hydrogenosome of Trichomonas vaginalis. | 2006 | Eukaryotic Cell | pmid:17158739 |
Hirani TA et al. | Asp295 stabilizes the active-site loop structure of pyruvate dehydrogenase, facilitating phosphorylation of ser292 by pyruvate dehydrogenase-kinase. | 2011 | Enzyme Res | pmid:21318135 |
Sawada K et al. | Cytosolic cofactors and dihydrolipoamide stimulate hepatic microsomal 5'-deiodination. | 1985 | Endocrinology | pmid:3926468 |
Goswami A and Rosenberg IN | Stimulation of iodothyronine outer ring monodeiodinase by dihydrolipoamide. | 1983 | Endocrinology | pmid:6187559 |
Kato M et al. | A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex. | 2006 | EMBO J. | pmid:17124494 |
Yan LJ et al. | Histochemical staining and quantification of dihydrolipoamide dehydrogenase diaphorase activity using blue native PAGE. | 2007 | Electrophoresis | pmid:17315258 |
Pang S et al. | Regulation of fasting fuel metabolism by toll-like receptor 4. | 2010 | Diabetes | pmid:20855545 |
Phelps PE et al. | Evidence for a cell-specific action of Reelin in the spinal cord. | 2002 | Dev. Biol. | pmid:11900467 |
Brown RM et al. | Pyruvate dehydrogenase E3 binding protein (protein X) deficiency. | 2006 | Dev Med Child Neurol | pmid:16904023 |
Keyes BE and Burke DJ | Irc15 Is a microtubule-associated protein that regulates microtubule dynamics in Saccharomyces cerevisiae. | 2009 | Curr. Biol. | pmid:19285398 |
Min CK et al. | Genome-based construction of the metabolic pathways of Orientia tsutsugamushi and comparative analysis within the Rickettsiales order. | 2008 | Comp. Funct. Genomics | pmid:18528528 |
Marie SK and Shinjo SM | Metabolism and brain cancer. | 2011 | Clinics (Sao Paulo) | pmid:21779721 |
Wu YY et al. | Proteinase 3 and dihydrolipoamide dehydrogenase (E3) are major autoantigens in hepatitis C virus (HCV) infection. | 2002 | Clin. Exp. Immunol. | pmid:11985526 |
Cicek G et al. | Analysis of mitochondrial antigens reveals inner membrane succinate dehydrogenase flavoprotein subunit as autoantigen to antibodies in anti-M7 sera. | 2002 | Clin. Exp. Immunol. | pmid:11982594 |
Zuñiga J et al. | Cellular and humoral mechanisms involved in the control of tuberculosis. | 2012 | Clin. Dev. Immunol. | pmid:22666281 |
Becker DM et al. | Optimal conditions for the assay of lipoamide dehydrogenase in homogenized human platelets. | 1982 | Clin. Chim. Acta | pmid:6805984 |
Chen HJ et al. | Lipoyl dehydrogenase catalyzes reduction of nitrated DNA and protein adducts using dihydrolipoic acid or ubiquinol as the cofactor. | 2002 | Chem. Biol. Interact. | pmid:12204577 |
Richardson AR et al. | Multiple targets of nitric oxide in the tricarboxylic acid cycle of Salmonella enterica serovar typhimurium. | 2011 | Cell Host Microbe | pmid:21767810 |
Venugopal A et al. | Virulence of Mycobacterium tuberculosis depends on lipoamide dehydrogenase, a member of three multienzyme complexes. | 2011 | Cell Host Microbe | pmid:21238944 |