Dihydrolipoamide

Dihydrolipoamide is a lipid of Fatty Acyls (FA) class. Dihydrolipoamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Citric Acid Cycle, Electron Transport, NADH oxidation, Oxidation and Oxidants. Dihydrolipoamide often locates in Mitochondria, Mitochondrial matrix and Chloroplasts. The associated genes with Dihydrolipoamide are Mutant Proteins, Recombinant Proteins, mycothione reductase, Genes, Mitochondrial and alanylproline.

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Introduction

To understand associated biological information of Dihydrolipoamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Dihydrolipoamide?

Dihydrolipoamide is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Dihydrolipoamide

MeSH term MeSH ID Detail
Parkinsonian Disorders D020734 20 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Dihydrolipoamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with Dihydrolipoamide?

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What functions are associated with Dihydrolipoamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Dihydrolipoamide?

There are no associated biomedical information in the current reference collection.

What genes are associated with Dihydrolipoamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Dihydrolipoamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Dihydrolipoamide

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Authors Title Published Journal PubMed Link
Jiang ZD and Wen YH [Expressions of c-Fos and NADPH-d in the related brainstem during vestibular compensation]. 2008 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:19180910
Liberti EA et al. Effects of combined pre- and post-natal protein deprivation on the myenteric plexus of the esophagus of weanling rats: a histochemical, quantitative and ultrastructural study. 2007 World J. Gastroenterol. pmid:17659710
Salcedo E et al. A glycine-cleavage complex as part of the folate one-carbon metabolism of Plasmodium falciparum. 2005 Trends Parasitol. pmid:16039160
Miller JA et al. 1,3-Dinitrobenzene-induced metabolic impairment through selective inactivation of the pyruvate dehydrogenase complex. 2011 Toxicol. Sci. pmid:21551353
Zhang Q et al. Dihydrolipoamide dehydrogenase and cAMP are associated with cadmium-mediated Leydig cell damage. 2011 Toxicol. Lett. pmid:21699967
Lee HM et al. Impaired mitochondrial respiration and protein nitration in the rat hippocampus after acute inhalation of combustion smoke. 2009 Toxicol. Appl. Pharmacol. pmid:19133281
Kurakin A Scale-free flow of life: on the biology, economics, and physics of the cell. 2009 Theor Biol Med Model pmid:19416527
Brautigam CA et al. Structural insight into interactions between dihydrolipoamide dehydrogenase (E3) and E3 binding protein of human pyruvate dehydrogenase complex. 2006 Structure pmid:16442803
Hohenester S et al. Primary biliary cirrhosis. 2009 Semin Immunopathol pmid:19603170
Bryk R et al. Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein. 2002 Science pmid:11799204
Crăiţoiu MM et al. Clinical and histoenzymatic interrelations of the edentulous ridge's mucosa. 2011 Rom J Morphol Embryol pmid:21424039
Sengupta J et al. Nitric oxide in blastocyst implantation in the rhesus monkey. 2005 Reproduction pmid:16123239
Johnson M et al. Maternal enzyme masks the phenotype of mouse embryos lacking dihydrolipoamide dehydrogenase. 2009 Reprod. Biomed. Online pmid:19573295
Wu TF et al. Proteomic investigation of the impact of oxygen on the protein profiles of hyaluronic acid-producing Streptococcus zooepidemicus. 2009 Proteomics pmid:19688725
Snoussi S et al. Adaptation of Salmonella enterica Hadar under static magnetic field: effects on outer membrane protein pattern. 2012 Proteome Sci pmid:22304719
Nam MH et al. Comparative proteomic analysis of early salt stress-responsive proteins in roots of SnRK2 transgenic rice. 2012 Proteome Sci pmid:22462395
Wang W et al. Proteome analysis of a recombinant Bacillus megaterium strain during heterologous production of a glucosyltransferase. 2005 Proteome Sci pmid:15927046
Ajith VK and Prasad R A novel protein that binds to dnrN-dnrO intergenic region of Streptomyces peucetius purified by DNA affinity capture has dihydrolipoamide dehydrogenase activity. 2009 Protein Expr. Purif. pmid:19481152
Self WT et al. Synthesis and characterization of selenotrisulfide-derivatives of lipoic acid and lipoamide. 2000 Proc. Natl. Acad. Sci. U.S.A. pmid:11050172
Feeney MA et al. Repurposing lipoic acid changes electron flow in two important metabolic pathways of Escherichia coli. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:21521794
Tyler KM et al. Limitation of Trypanosoma brucei parasitaemia results from density-dependent parasite differentiation and parasite killing by the host immune response. 2001 Proc. Biol. Sci. pmid:11674871
Pino P et al. Dual targeting of antioxidant and metabolic enzymes to the mitochondrion and the apicoplast of Toxoplasma gondii. 2007 PLoS Pathog. pmid:17784785
Günther S et al. Apicoplast lipoic acid protein ligase B is not essential for Plasmodium falciparum. 2007 PLoS Pathog. pmid:18069893
Kehr S et al. Compartmentation of redox metabolism in malaria parasites. 2010 PLoS Pathog. pmid:21203490
Gómez-Baena G et al. Glucose uptake and its effect on gene expression in prochlorococcus. 2008 PLoS ONE pmid:18941506
Stöckel J et al. Diurnal rhythms result in significant changes in the cellular protein complement in the cyanobacterium Cyanothece 51142. 2011 PLoS ONE pmid:21364985
Phillips NJ et al. Proteomic analysis of Neisseria gonorrhoeae biofilms shows shift to anaerobic respiration and changes in nutrient transport and outermembrane proteins. 2012 PLoS ONE pmid:22701624
van der Lelie D et al. The metagenome of an anaerobic microbial community decomposing poplar wood chips. 2012 PLoS ONE pmid:22629327
Redanz S et al. A five-species transcriptome array for oral mixed-biofilm studies. 2011 PLoS ONE pmid:22194794
Garbeva P et al. No apparent costs for facultative antibiotic production by the soil bacterium Pseudomonas fluorescens Pf0-1. 2011 PLoS ONE pmid:22110622
Sandoval JM et al. Glucose-6-phosphate dehydrogenase protects Escherichia coli from tellurite-mediated oxidative stress. 2011 PLoS ONE pmid:21984934
Wang N et al. Display of Bombyx mori alcohol dehydrogenases on the Bacillus subtilis spore surface to enhance enzymatic activity under adverse conditions. 2011 PLoS ONE pmid:21738670
Harvey RM et al. A variable region within the genome of Streptococcus pneumoniae contributes to strain-strain variation in virulence. 2011 PLoS ONE pmid:21573186
Xiao Z et al. Acetoin catabolism and acetylbutanediol formation by Bacillus pumilus in a chemically defined medium. 2009 PLoS ONE pmid:19461961
Charles RC et al. Comparative proteomic analysis of the PhoP regulon in Salmonella enterica serovar Typhi versus Typhimurium. 2009 PLoS ONE pmid:19746165
Hakansson AP et al. Apoptosis-like death in bacteria induced by HAMLET, a human milk lipid-protein complex. 2011 PLoS ONE pmid:21423701
Sianglum W et al. Proteome analyses of cellular proteins in methicillin-resistant Staphylococcus aureus treated with rhodomyrtone, a novel antibiotic candidate. 2011 PLoS ONE pmid:21326597
Günther S et al. Knockout studies reveal an important role of Plasmodium lipoic acid protein ligase A1 for asexual blood stage parasite survival. 2009 PLoS ONE pmid:19434237
Dozot M et al. Functional characterization of the incomplete phosphotransferase system (PTS) of the intracellular pathogen Brucella melitensis. 2010 PLoS ONE pmid:20844759
Marselli L et al. Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes. 2010 PLoS ONE pmid:20644627
Li Y et al. The complete genome sequence of Mycoplasma bovis strain Hubei-1. 2011 PLoS ONE pmid:21731639
Marques B et al. Liposome-mediated cellular delivery of active gp91(phox). 2007 PLoS ONE pmid:17848987
Heinicke S et al. The Princeton Protein Orthology Database (P-POD): a comparative genomics analysis tool for biologists. 2007 PLoS ONE pmid:17712414
Vazquez A et al. Serine biosynthesis with one carbon catabolism and the glycine cleavage system represents a novel pathway for ATP generation. 2011 PLoS ONE pmid:22073143
Viadas C et al. Transcriptome analysis of the Brucella abortus BvrR/BvrS two-component regulatory system. 2010 PLoS ONE pmid:20422049
Mochel F et al. Early energy deficit in Huntington disease: identification of a plasma biomarker traceable during disease progression. 2007 PLoS ONE pmid:17653274
Castro H et al. Mitochondrial redox metabolism in trypanosomatids is independent of tryparedoxin activity. 2010 PLoS ONE pmid:20838623
Chadwick W et al. Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses. 2010 PLoS ONE pmid:21179406
Wang Q et al. Genome sequence of the versatile fish pathogen Edwardsiella tarda provides insights into its adaptation to broad host ranges and intracellular niches. 2009 PLoS ONE pmid:19865481
Skapski A et al. Genome-scale analysis of Mycoplasma agalactiae loci involved in interaction with host cells. 2011 PLoS ONE pmid:21966487
Jiang H et al. Global analysis of gene expression profiles in developing physic nut (Jatropha curcas L.) seeds. 2012 PLoS ONE pmid:22574177
Bruant G et al. Genomic analysis of carbon monoxide utilization and butanol production by Clostridium carboxidivorans strain P7. 2010 PLoS ONE pmid:20885952
Spalding MD and Prigge ST The amidase domain of lipoamidase specifically inactivates lipoylated proteins in vivo. 2009 PLoS ONE pmid:19812687
Xue F et al. Transcriptional responses of Leptospira interrogans to host innate immunity: significant changes in metabolism, oxygen tolerance, and outer membrane. 2010 PLoS Negl Trop Dis pmid:21049008
Liang L et al. Large scale immune profiling of infected humans and goats reveals differential recognition of Brucella melitensis antigens. 2010 PLoS Negl Trop Dis pmid:20454614
Alvaro D et al. Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. 2007 PLoS Genet. pmid:18085829
Mongodin EF et al. Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1. 2006 PLoS Genet. pmid:17194220
Ndifon W et al. On the accessibility of adaptive phenotypes of a bacterial metabolic network. 2009 PLoS Comput. Biol. pmid:19696877
Marino SM and Gladyshev VN A structure-based approach for detection of thiol oxidoreductases and their catalytic redox-active cysteine residues. 2009 PLoS Comput. Biol. pmid:19424433
White JR et al. Statistical methods for detecting differentially abundant features in clinical metagenomic samples. 2009 PLoS Comput. Biol. pmid:19360128
Ojha S et al. Evolution of function in the "two dinucleotide binding domains" flavoproteins. 2007 PLoS Comput. Biol. pmid:17658942
Leichert LI and Jakob U Protein thiol modifications visualized in vivo. 2004 PLoS Biol. pmid:15502869
Moran JF et al. Molecular cloning, functional characterization, and subcellular localization of soybean nodule dihydrolipoamide reductase. 2002 Plant Physiol. pmid:11788775
Chen W et al. Disruption of ptLPD1 or ptLPD2, genes that encode isoforms of the plastidial lipoamide dehydrogenase, confers arsenate hypersensitivity in Arabidopsis. 2010 Plant Physiol. pmid:20488895
Lutziger I and Oliver DJ Characterization of two cDNAs encoding mitochondrial lipoamide dehydrogenase from Arabidopsis. 2001 Plant Physiol. pmid:11598235
Fujiki Y et al. Activation of the promoters of Arabidopsis genes for the branched-chain alpha-keto acid dehydrogenase complex in transgenic tobacco BY-2 cells under sugar starvation. 2002 Plant Cell Physiol. pmid:11917081
Calingasan NY et al. Influence of mitochondrial enzyme deficiency on adult neurogenesis in mouse models of neurodegenerative diseases. 2008 Neuroscience pmid:18423880
Ten VS and Starkov A Hypoxic-ischemic injury in the developing brain: the role of reactive oxygen species originating in mitochondria. 2012 Neurol Res Int pmid:22548167
Rezzani R et al. Does methylene blue protect the kidney tissues from damage induced by ciclosporin A treatment? 2001 Nephron pmid:11598398
Liu DQ et al. [Microwave coagulation at different temperatures for hepatocellular carcinoma management: efficacy evaluation by enzyme histochemical staining]. 2006 Nan Fang Yi Ke Da Xue Xue Bao pmid:16939906
Suetsugu-Maki R et al. A complement receptor C5a antagonist regulates epithelial to mesenchymal transition and crystallin expression after lens cataract surgery in mice. 2011 Mol. Vis. pmid:21541266
Vyas PM and Payne RM TAT opens the door. 2008 Mol. Ther. pmid:18362922
Rapoport M et al. TAT-mediated delivery of LAD restores pyruvate dehydrogenase complex activity in the mitochondria of patients with LAD deficiency. 2008 Mol. Ther. pmid:18362926
de Berardinis V et al. A complete collection of single-gene deletion mutants of Acinetobacter baylyi ADP1. 2008 Mol. Syst. Biol. pmid:18319726
McMillan PJ et al. The human malaria parasite Plasmodium falciparum possesses two distinct dihydrolipoamide dehydrogenases. 2005 Mol. Microbiol. pmid:15612914
Leach MD et al. Molecular and proteomic analyses highlight the importance of ubiquitination for the stress resistance, metabolic adaptation, morphogenetic regulation and virulence of Candida albicans. 2011 Mol. Microbiol. pmid:21269335
Roldán A et al. Lipoamide dehydrogenase is essential for both bloodstream and procyclic Trypanosoma brucei. 2011 Mol. Microbiol. pmid:21631607
Smith AW et al. Characterization of the dihydrolipoamide dehydrogenase from Streptococcus pneumoniae and its role in pneumococcal infection. 2002 Mol. Microbiol. pmid:11972781
Pei Y et al. Plasmodium pyruvate dehydrogenase activity is only essential for the parasite's progression from liver infection to blood infection. 2010 Mol. Microbiol. pmid:20487290
Boucher IW et al. Structural and biochemical characterization of a mitochondrial peroxiredoxin from Plasmodium falciparum. 2006 Mol. Microbiol. pmid:16879648
Tian J et al. Mycobacterium tuberculosis appears to lack alpha-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes. 2005 Mol. Microbiol. pmid:16045627
de Graaf RM et al. The organellar genome and metabolic potential of the hydrogen-producing mitochondrion of Nyctotherus ovalis. 2011 Mol. Biol. Evol. pmid:21378103
Fairlamb AH et al. The interaction of arsenical drugs with dihydrolipoamide and dihydrolipoamide dehydrogenase from arsenical resistant and sensitive strains of Trypanosoma brucei brucei. 1992 Mol. Biochem. Parasitol. pmid:1501642
Deringer JR et al. Immunoreactive Coxiella burnetii Nine Mile proteins separated by 2D electrophoresis and identified by tandem mass spectrometry. 2011 Microbiology (Reading, Engl.) pmid:21030434
Sastalla I et al. Activation of the latent PlcR regulon in Bacillus anthracis. 2010 Microbiology (Reading, Engl.) pmid:20688829
Gallo G et al. Differential proteomic analysis highlights metabolic strategies associated with balhimycin production in Amycolatopsis balhimycina chemostat cultivations. 2010 Microb. Cell Fact. pmid:21110849
Lu X et al. The intra- and extracellular proteome of Aspergillus niger growing on defined medium with xylose or maltose as carbon substrate. 2010 Microb. Cell Fact. pmid:20406453
Peano C et al. Comparative genomics and transcriptional profiles of Saccharopolyspora erythraea NRRL 2338 and a classically improved erythromycin over-producing strain. 2012 Microb. Cell Fact. pmid:22401291
Yao R et al. Catabolic regulation analysis of Escherichia coli and its crp, mlc, mgsA, pgi and ptsG mutants. 2011 Microb. Cell Fact. pmid:21831320
Patel MS and Hong YS Lipoic acid as an antioxidant. The role of dihydrolipoamide dehydrogenase. 1998 Methods Mol. Biol. pmid:9921542
Patel MS et al. Dihydrolipoamide dehydrogenase: activity assays. 1995 Meth. Enzymol. pmid:7476353
Yan LJ et al. Changes in dihydrolipoamide dehydrogenase expression and activity during postnatal development and aging in the rat brain. 2008 Mech. Ageing Dev. pmid:18316113
Chavarría M et al. Regulatory tasks of the phosphoenolpyruvate-phosphotransferase system of Pseudomonas putida in central carbon metabolism. 2012 MBio pmid:22434849
Koti RS et al. Effect of ischemic preconditioning on hepatic microcirculation and function in a rat model of ischemia reperfusion injury. 2002 Liver Transpl. pmid:12474159
Shaco-Levy R et al. On appropriate pathology for photothermal surgery. 2004 Lasers Surg Med pmid:15278925
Holbrook ED et al. Definition of the extracellular proteome of pathogenic-phase Histoplasma capsulatum. 2011 J. Proteome Res. pmid:21291285
Campanucci VA et al. A novel O2-sensing mechanism in rat glossopharyngeal neurones mediated by a halothane-inhibitable background K+ conductance. 2003 J. Physiol. (Lond.) pmid:12640017
Ramos EI et al. 2,3-diphenyl-1,4-naphthoquinone: a potential chemotherapeutic agent against Trypanosoma cruzi. 2009 J. Parasitol. pmid:18788881
Starkov AA et al. Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species. 2004 J. Neurosci. pmid:15356189
Ambrus A et al. Inhibition of the alpha-ketoglutarate dehydrogenase-mediated reactive oxygen species generation by lipoic acid. 2009 J. Neurochem. pmid:19393031