Dihydrolipoamide

Dihydrolipoamide is a lipid of Fatty Acyls (FA) class. Dihydrolipoamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Citric Acid Cycle, Electron Transport, NADH oxidation, Oxidation and Oxidants. Dihydrolipoamide often locates in Mitochondria, Mitochondrial matrix and Chloroplasts. The associated genes with Dihydrolipoamide are Mutant Proteins, Recombinant Proteins, mycothione reductase, Genes, Mitochondrial and alanylproline.

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Introduction

To understand associated biological information of Dihydrolipoamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Dihydrolipoamide?

Dihydrolipoamide is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Dihydrolipoamide

MeSH term MeSH ID Detail
Parkinsonian Disorders D020734 20 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Dihydrolipoamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with Dihydrolipoamide?

Related references are published most in these journals:

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What functions are associated with Dihydrolipoamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Dihydrolipoamide?

There are no associated biomedical information in the current reference collection.

What genes are associated with Dihydrolipoamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Dihydrolipoamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Dihydrolipoamide

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Authors Title Published Journal PubMed Link
pmid:
Szabados E et al. Enhanced ADP-ribosylation and its diminution by lipoamide after ischemia-reperfusion in perfused rat heart. 1999 Free Radic. Biol. Med. pmid:10569643
Faure M et al. Interaction between the lipoamide-containing H-protein and the lipoamide dehydrogenase (L-protein) of the glycine decarboxylase multienzyme system 2. Crystal structures of H- and L-proteins. 2000 Eur. J. Biochem. pmid:10806386
Self WT et al. Synthesis and characterization of selenotrisulfide-derivatives of lipoic acid and lipoamide. 2000 Proc. Natl. Acad. Sci. U.S.A. pmid:11050172
Piasecka M et al. Computerized analysis of cytochemical reactions for dehydrogenases and oxygraphic studies as methods to evaluate the function of the mitochondrial sheath in rat spermatozoa. 2001 Andrologia pmid:11167513
Ono K et al. cDNA cloning of the chicken branched-chain alpha-keto acid dehydrogenase complex. Chicken-specific residues of the acyltransferase affect the overall activity and the interaction with the dehydrogenase. 2001 Eur. J. Biochem. pmid:11168412
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Xia L et al. Reduction of ubiquinone by lipoamide dehydrogenase. An antioxidant regenerating pathway. 2001 Eur. J. Biochem. pmid:11231302
Katsuki H et al. Superoxide dismutase activity in organotypic midbrain-striatum co-cultures is associated with resistance of dopaminergic neurons to excitotoxicity. 2001 J. Neurochem. pmid:11238718
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Fregonesi CE et al. Quantitative study of the myenteric plexus of the stomach of rats with streptozotocin-induced diabetes. 2001 Arq Neuropsiquiatr pmid:11299431
Korotchkina LG et al. Protection by thiols of the mitochondrial complexes from 4-hydroxy-2-nonenal. 2001 Free Radic. Biol. Med. pmid:11316579
Moraes N et al. NADPH-diaphorase activity and nitric oxide synthase isoforms in the trophoblast of Calomys callosus. 2001 J. Anat. pmid:11327206
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Liu S et al. Reaction mechanism for mammalian pyruvate dehydrogenase using natural lipoyl domain substrates. 2001 Arch. Biochem. Biophys. pmid:11368334
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Pessach I et al. Essential requirement of cytosolic phospholipase A(2) for stimulation of NADPH oxidase-associated diaphorase activity in granulocyte-like cells. 2001 J. Biol. Chem. pmid:11432850
Fischer A et al. Effect of selenium and vitamin E deficiency on differential gene expression in rat liver. 2001 Biochem. Biophys. Res. Commun. pmid:11444866
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Tozawa K et al. Solution structure of the lipoyl domain of the chimeric dihydrolipoyl dehydrogenase P64K from Neisseria meningitidis. 2001 Eur. J. Biochem. pmid:11559360
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Sant'Ana DM et al. Effects of protein and vitamin B deficiency on blood parameters and myenteric neurons of the colon of rats. 2001 Arq Neuropsiquiatr pmid:11588624
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Lutziger I and Oliver DJ Characterization of two cDNAs encoding mitochondrial lipoamide dehydrogenase from Arabidopsis. 2001 Plant Physiol. pmid:11598235
Rezzani R et al. Does methylene blue protect the kidney tissues from damage induced by ciclosporin A treatment? 2001 Nephron pmid:11598398
pmid:11603835
Tyler KM et al. Limitation of Trypanosoma brucei parasitaemia results from density-dependent parasite differentiation and parasite killing by the host immune response. 2001 Proc. Biol. Sci. pmid:11674871
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Gazaryan IG et al. Zinc is a potent inhibitor of thiol oxidoreductase activity and stimulates reactive oxygen species production by lipoamide dehydrogenase. 2002 J. Biol. Chem. pmid:11744691
Jacobia SJ et al. Characterization of a missense mutation at histidine-44 in a pyruvate dehydrogenase-deficient patient. 2002 Biochim. Biophys. Acta pmid:11781147
Moran JF et al. Molecular cloning, functional characterization, and subcellular localization of soybean nodule dihydrolipoamide reductase. 2002 Plant Physiol. pmid:11788775
Bryk R et al. Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein. 2002 Science pmid:11799204
pmid:11830363
Phelps PE et al. Evidence for a cell-specific action of Reelin in the spinal cord. 2002 Dev. Biol. pmid:11900467
Fujiki Y et al. Activation of the promoters of Arabidopsis genes for the branched-chain alpha-keto acid dehydrogenase complex in transgenic tobacco BY-2 cells under sugar starvation. 2002 Plant Cell Physiol. pmid:11917081
Olsson C Distribution and effects of PACAP, VIP, nitric oxide and GABA in the gut of the African clawed frog Xenopus laevis. 2002 J. Exp. Biol. pmid:11919271
Pedrajas JR et al. Two isoforms of Saccharomyces cerevisiae glutaredoxin 2 are expressed in vivo and localize to different subcellular compartments. 2002 Biochem. J. pmid:11958675
Smith AW et al. Characterization of the dihydrolipoamide dehydrogenase from Streptococcus pneumoniae and its role in pneumococcal infection. 2002 Mol. Microbiol. pmid:11972781
Gao H et al. The E1beta and E2 subunits of the Bacillus subtilis pyruvate dehydrogenase complex are involved in regulation of sporulation. 2002 J. Bacteriol. pmid:11976308
Cicek G et al. Analysis of mitochondrial antigens reveals inner membrane succinate dehydrogenase flavoprotein subunit as autoantigen to antibodies in anti-M7 sera. 2002 Clin. Exp. Immunol. pmid:11982594
Wu YY et al. Proteinase 3 and dihydrolipoamide dehydrogenase (E3) are major autoantigens in hepatitis C virus (HCV) infection. 2002 Clin. Exp. Immunol. pmid:11985526