Dihydrolipoamide

Dihydrolipoamide is a lipid of Fatty Acyls (FA) class. Dihydrolipoamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Citric Acid Cycle, Electron Transport, NADH oxidation, Oxidation and Oxidants. Dihydrolipoamide often locates in Mitochondria, Mitochondrial matrix and Chloroplasts. The associated genes with Dihydrolipoamide are Mutant Proteins, Recombinant Proteins, mycothione reductase, Genes, Mitochondrial and alanylproline.

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Introduction

To understand associated biological information of Dihydrolipoamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Dihydrolipoamide?

Dihydrolipoamide is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Dihydrolipoamide

MeSH term MeSH ID Detail
Parkinsonian Disorders D020734 20 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Dihydrolipoamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Dihydrolipoamide?

Related references are published most in these journals:

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What functions are associated with Dihydrolipoamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Dihydrolipoamide?

There are no associated biomedical information in the current reference collection.

What genes are associated with Dihydrolipoamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Dihydrolipoamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Dihydrolipoamide

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Authors Title Published Journal PubMed Link
Brautigam CA et al. Structural insight into interactions between dihydrolipoamide dehydrogenase (E3) and E3 binding protein of human pyruvate dehydrogenase complex. 2006 Structure pmid:16442803
Ciszak EM et al. How dihydrolipoamide dehydrogenase-binding protein binds dihydrolipoamide dehydrogenase in the human pyruvate dehydrogenase complex. 2006 J. Biol. Chem. pmid:16263718
McMillan PJ et al. The human malaria parasite Plasmodium falciparum possesses two distinct dihydrolipoamide dehydrogenases. 2005 Mol. Microbiol. pmid:15612914
Mersey BD et al. Human microRNA (miR29b) expression controls the amount of branched chain alpha-ketoacid dehydrogenase complex in a cell. 2005 Hum. Mol. Genet. pmid:16203741
Odièvre MH et al. A novel mutation in the dihydrolipoamide dehydrogenase E3 subunit gene (DLD) resulting in an atypical form of alpha-ketoglutarate dehydrogenase deficiency. 2005 Hum. Mutat. pmid:15712224
Brautigam CA et al. Crystal structure of human dihydrolipoamide dehydrogenase: NAD+/NADH binding and the structural basis of disease-causing mutations. 2005 J. Mol. Biol. pmid:15946682
Sengupta J et al. Nitric oxide in blastocyst implantation in the rhesus monkey. 2005 Reproduction pmid:16123239
Salcedo E et al. A glycine-cleavage complex as part of the folate one-carbon metabolism of Plasmodium falciparum. 2005 Trends Parasitol. pmid:16039160
Da Sylva TR et al. Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes. 2005 Arthritis Res. Ther. pmid:15987486
Vernon SD and Reeves WC Evaluation of autoantibodies to common and neuronal cell antigens in Chronic Fatigue Syndrome. 2005 J Autoimmune Dis pmid:15916704
Mitra K et al. Novelty of the pyruvate metabolic enzyme dihydrolipoamide dehydrogenase in spermatozoa: correlation of its localization, tyrosine phosphorylation, and activity during sperm capacitation. 2005 J. Biol. Chem. pmid:15888450
Sauer SW et al. Bioenergetics in glutaryl-coenzyme A dehydrogenase deficiency: a role for glutaryl-coenzyme A. 2005 J. Biol. Chem. pmid:15840571
Li XJ et al. Crucial role of two potential cytosolic regions of Nox2, 191TSSTKTIRRS200 and 484DESQANHFAVHHDEEKD500, on NADPH oxidase activation. 2005 J. Biol. Chem. pmid:15684431
Wang W et al. Proteome analysis of a recombinant Bacillus megaterium strain during heterologous production of a glucosyltransferase. 2005 Proteome Sci pmid:15927046
Rajashankar KR et al. Crystal structure and functional analysis of lipoamide dehydrogenase from Mycobacterium tuberculosis. 2005 J. Biol. Chem. pmid:16093239
Tian J et al. Mycobacterium tuberculosis appears to lack alpha-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes. 2005 Mol. Microbiol. pmid:16045627
Klyachko NL et al. pH-dependent substrate preference of pig heart lipoamide dehydrogenase varies with oligomeric state: response to mitochondrial matrix acidification. 2005 J. Biol. Chem. pmid:15710613
Deres P et al. Prevention of doxorubicin-induced acute cardiotoxicity by an experimental antioxidant compound. 2005 J. Cardiovasc. Pharmacol. pmid:15613977
Shaco-Levy R et al. On appropriate pathology for photothermal surgery. 2004 Lasers Surg Med pmid:15278925
Rani K et al. Measurement of bile acid in serum and bile with arylamine-glass-bound 3alpha-hydroxysteroid dehydrogenase and diaphorase. 2004 Anal. Biochem. pmid:15301946