MeSH term | MeSH ID | Detail |
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Parkinsonian Disorders | D020734 | 20 associated lipids |
Dihydrolipoamide is a lipid of Fatty Acyls (FA) class. Dihydrolipoamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Citric Acid Cycle, Electron Transport, NADH oxidation, Oxidation and Oxidants. Dihydrolipoamide often locates in Mitochondria, Mitochondrial matrix and Chloroplasts. The associated genes with Dihydrolipoamide are Mutant Proteins, Recombinant Proteins, mycothione reductase, Genes, Mitochondrial and alanylproline.
To understand associated biological information of Dihydrolipoamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Dihydrolipoamide is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Dihydrolipoamide
MeSH term | MeSH ID | Detail |
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Parkinsonian Disorders | D020734 | 20 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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LuÃs PB et al. | Valproic acid metabolites inhibit dihydrolipoyl dehydrogenase activity leading to impaired 2-oxoglutarate-driven oxidative phosphorylation. | 2007 | Biochim. Biophys. Acta | pmid:17706936 |
Jacobia SJ et al. | Characterization of a missense mutation at histidine-44 in a pyruvate dehydrogenase-deficient patient. | 2002 | Biochim. Biophys. Acta | pmid:11781147 |
Song J and Jordan F | Interchain acetyl transfer in the E2 component of bacterial pyruvate dehydrogenase suggests a model with different roles for each chain in a trimer of the homooligomeric component. | 2012 | Biochemistry | pmid:22413895 |
Argyrou A et al. | Catalysis of diaphorase reactions by Mycobacterium tuberculosis lipoamide dehydrogenase occurs at the EH4 level. | 2003 | Biochemistry | pmid:12590611 |
Argyrou A et al. | The lipoamide dehydrogenase from Mycobacterium tuberculosis permits the direct observation of flavin intermediates in catalysis. | 2002 | Biochemistry | pmid:12463758 |
Bryk R et al. | Triazaspirodimethoxybenzoyls as selective inhibitors of mycobacterial lipoamide dehydrogenase . | 2010 | Biochemistry | pmid:20078138 |
Molina Portela MP and Stoppani AO | Redox cycling of beta-lapachone and related o-naphthoquinones in the presence of dihydrolipoamide and oxygen. | 1996 | Biochem. Pharmacol. | pmid:8573194 |
McCully V et al. | Resolution of branched-chain oxo acid dehydrogenase complex of Pseudomonas aeruginosa PAO. | 1986 | Biochem. J. | pmid:3085653 |
Murphy MP | How mitochondria produce reactive oxygen species. | 2009 | Biochem. J. | pmid:19061483 |
Pedrajas JR et al. | Two isoforms of Saccharomyces cerevisiae glutaredoxin 2 are expressed in vivo and localize to different subcellular compartments. | 2002 | Biochem. J. | pmid:11958675 |
Porras P et al. | Glutaredoxins catalyze the reduction of glutathione by dihydrolipoamide with high efficiency. | 2002 | Biochem. Biophys. Res. Commun. | pmid:12135599 |
Park YH and Patel MS | Characterization of interactions of dihydrolipoamide dehydrogenase with its binding protein in the human pyruvate dehydrogenase complex. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20385101 |
Fischer A et al. | Effect of selenium and vitamin E deficiency on differential gene expression in rat liver. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11444866 |
Tsiveriotis K et al. | Antineutrophil cytoplasmic antibodies testing in a large cohort of unselected greek patients. | 2011 | Autoimmune Dis | pmid:21687647 |
Régent A et al. | Identification of target antigens of anti-endothelial cell and anti-vascular smooth muscle cell antibodies in patients with giant cell arteritis: a proteomic approach. | 2011 | Arthritis Res. Ther. | pmid:21711540 |
Da Sylva TR et al. | Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes. | 2005 | Arthritis Res. Ther. | pmid:15987486 |
Araújo EJ et al. | Effect of protein and vitamin B deficiency on the morpho-quantitative aspects of the myenteric plexus of the descending colon of adult rats. | 2003 | Arq Neuropsiquiatr | pmid:12806501 |
Sant'Ana DM et al. | Effects of protein and vitamin B deficiency on blood parameters and myenteric neurons of the colon of rats. | 2001 | Arq Neuropsiquiatr | pmid:11588624 |
Fregonesi CE et al. | Quantitative study of the myenteric plexus of the stomach of rats with streptozotocin-induced diabetes. | 2001 | Arq Neuropsiquiatr | pmid:11299431 |
Liu S et al. | Reaction mechanism for mammalian pyruvate dehydrogenase using natural lipoyl domain substrates. | 2001 | Arch. Biochem. Biophys. | pmid:11368334 |