MeSH term | MeSH ID | Detail |
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Parkinsonian Disorders | D020734 | 20 associated lipids |
Dihydrolipoamide is a lipid of Fatty Acyls (FA) class. Dihydrolipoamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Citric Acid Cycle, Electron Transport, NADH oxidation, Oxidation and Oxidants. Dihydrolipoamide often locates in Mitochondria, Mitochondrial matrix and Chloroplasts. The associated genes with Dihydrolipoamide are Mutant Proteins, Recombinant Proteins, mycothione reductase, Genes, Mitochondrial and alanylproline.
To understand associated biological information of Dihydrolipoamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Dihydrolipoamide is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Dihydrolipoamide
MeSH term | MeSH ID | Detail |
---|---|---|
Parkinsonian Disorders | D020734 | 20 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Hall BS et al. | Nifurtimox activation by trypanosomal type I nitroreductases generates cytotoxic nitrile metabolites. | 2011 | J. Biol. Chem. | pmid:21345801 |
Sianglum W et al. | Proteome analyses of cellular proteins in methicillin-resistant Staphylococcus aureus treated with rhodomyrtone, a novel antibiotic candidate. | 2011 | PLoS ONE | pmid:21326597 |
Hirani TA et al. | Asp295 stabilizes the active-site loop structure of pyruvate dehydrogenase, facilitating phosphorylation of ser292 by pyruvate dehydrogenase-kinase. | 2011 | Enzyme Res | pmid:21318135 |
Packer L and Cadenas E | Lipoic acid: energy metabolism and redox regulation of transcription and cell signaling. | 2011 | J Clin Biochem Nutr | pmid:21297908 |
Holbrook ED et al. | Definition of the extracellular proteome of pathogenic-phase Histoplasma capsulatum. | 2011 | J. Proteome Res. | pmid:21291285 |
Leach MD et al. | Molecular and proteomic analyses highlight the importance of ubiquitination for the stress resistance, metabolic adaptation, morphogenetic regulation and virulence of Candida albicans. | 2011 | Mol. Microbiol. | pmid:21269335 |
Venugopal A et al. | Virulence of Mycobacterium tuberculosis depends on lipoamide dehydrogenase, a member of three multienzyme complexes. | 2011 | Cell Host Microbe | pmid:21238944 |
Thangthaeng N et al. | Nongradient blue native gel analysis of serum proteins and in-gel detection of serum esterase activities. | 2011 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:21237726 |
Kehr S et al. | Compartmentation of redox metabolism in malaria parasites. | 2010 | PLoS Pathog. | pmid:21203490 |
Sun J et al. | Constraint-based modeling analysis of the metabolism of two Pelobacter species. | 2010 | BMC Syst Biol | pmid:21182788 |
Chadwick W et al. | Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses. | 2010 | PLoS ONE | pmid:21179406 |
Kareyeva AV et al. | Molecular identification of the enzyme responsible for the mitochondrial NADH-supported ammonium-dependent hydrogen peroxide production. | 2011 | FEBS Lett. | pmid:21168410 |
Sasaki M and Nakanuma Y | Biliary epithelial apoptosis, autophagy, and senescence in primary biliary cirrhosis. | 2010 | Hepat Res Treat | pmid:21152179 |
Chadwick W et al. | Complex and multidimensional lipid raft alterations in a murine model of Alzheimer's disease. | 2010 | Int J Alzheimers Dis | pmid:21151659 |
Gallo G et al. | Differential proteomic analysis highlights metabolic strategies associated with balhimycin production in Amycolatopsis balhimycina chemostat cultivations. | 2010 | Microb. Cell Fact. | pmid:21110849 |
Folsom JP et al. | Physiology of Pseudomonas aeruginosa in biofilms as revealed by transcriptome analysis. | 2010 | BMC Microbiol. | pmid:21083928 |
pmid:21079907 | ||||
Xue F et al. | Transcriptional responses of Leptospira interrogans to host innate immunity: significant changes in metabolism, oxygen tolerance, and outer membrane. | 2010 | PLoS Negl Trop Dis | pmid:21049008 |
Trofimova L et al. | Behavioral impact of the regulation of the brain 2-oxoglutarate dehydrogenase complex by synthetic phosphonate analog of 2-oxoglutarate: implications into the role of the complex in neurodegenerative diseases. | 2010 | Int J Alzheimers Dis | pmid:21049004 |
Deringer JR et al. | Immunoreactive Coxiella burnetii Nine Mile proteins separated by 2D electrophoresis and identified by tandem mass spectrometry. | 2011 | Microbiology (Reading, Engl.) | pmid:21030434 |
pmid:20950843 | ||||
pmid:20950219 | ||||
Peplinski K et al. | Investigations on the microbial catabolism of the organic sulfur compounds TDP and DTDP in Ralstonia eutropha H16 employing DNA microarrays. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20924576 |
Bruant G et al. | Genomic analysis of carbon monoxide utilization and butanol production by Clostridium carboxidivorans strain P7. | 2010 | PLoS ONE | pmid:20885952 |
pmid:20862572 | ||||
Pang S et al. | Regulation of fasting fuel metabolism by toll-like receptor 4. | 2010 | Diabetes | pmid:20855545 |
pmid:20848047 | ||||
Dozot M et al. | Functional characterization of the incomplete phosphotransferase system (PTS) of the intracellular pathogen Brucella melitensis. | 2010 | PLoS ONE | pmid:20844759 |
Castro H et al. | Mitochondrial redox metabolism in trypanosomatids is independent of tryparedoxin activity. | 2010 | PLoS ONE | pmid:20838623 |
Gutiérrez-Correa J | Trypanosoma cruzi dihydrolipoamide dehydrogenase as target of reactive metabolites generated by cytochrome c/hydrogen peroxide (or linoleic acid hydroperoxide)/phenol systems. | 2010 | Free Radic. Res. | pmid:20815787 |
Aranjuelo I et al. | Plant physiology and proteomics reveals the leaf response to drought in alfalfa (Medicago sativa L.). | 2011 | J. Exp. Bot. | pmid:20797998 |
pmid:20739172 | ||||
He M et al. | Characterization and genomic analysis of chromate resistant and reducing Bacillus cereus strain SJ1. | 2010 | BMC Microbiol. | pmid:20723231 |
Sastalla I et al. | Activation of the latent PlcR regulon in Bacillus anthracis. | 2010 | Microbiology (Reading, Engl.) | pmid:20688829 |
pmid:20683787 | ||||
Quintana E et al. | Dihydrolipoamide dehydrogenase (DLD) deficiency in a Spanish patient with myopathic presentation due to a new mutation in the interface domain. | 2010 | J. Inherit. Metab. Dis. | pmid:20652410 |
Marselli L et al. | Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes. | 2010 | PLoS ONE | pmid:20644627 |
Kim SY and Kim J | Roles of dihydrolipoamide dehydrogenase Lpd1 in Candida albicans filamentation. | 2010 | Fungal Genet. Biol. | pmid:20601046 |
Ma M and Liu LZ | Quantitative transcription dynamic analysis reveals candidate genes and key regulators for ethanol tolerance in Saccharomyces cerevisiae. | 2010 | BMC Microbiol. | pmid:20537179 |
MacGregor P and Matthews KR | New discoveries in the transmission biology of sleeping sickness parasites: applying the basics. | 2010 | J. Mol. Med. | pmid:20526573 |
Wei LQ et al. | Genome-scale analysis and comparison of gene expression profiles in developing and germinated pollen in Oryza sativa. | 2010 | BMC Genomics | pmid:20507633 |
Chen W et al. | Disruption of ptLPD1 or ptLPD2, genes that encode isoforms of the plastidial lipoamide dehydrogenase, confers arsenate hypersensitivity in Arabidopsis. | 2010 | Plant Physiol. | pmid:20488895 |
Pei Y et al. | Plasmodium pyruvate dehydrogenase activity is only essential for the parasite's progression from liver infection to blood infection. | 2010 | Mol. Microbiol. | pmid:20487290 |
Liang L et al. | Large scale immune profiling of infected humans and goats reveals differential recognition of Brucella melitensis antigens. | 2010 | PLoS Negl Trop Dis | pmid:20454614 |
Viadas C et al. | Transcriptome analysis of the Brucella abortus BvrR/BvrS two-component regulatory system. | 2010 | PLoS ONE | pmid:20422049 |
Lu X et al. | The intra- and extracellular proteome of Aspergillus niger growing on defined medium with xylose or maltose as carbon substrate. | 2010 | Microb. Cell Fact. | pmid:20406453 |
Park YH and Patel MS | Characterization of interactions of dihydrolipoamide dehydrogenase with its binding protein in the human pyruvate dehydrogenase complex. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20385101 |
Otero L et al. | Thioredoxin and glutathione systems differ in parasitic and free-living platyhelminths. | 2010 | BMC Genomics | pmid:20385027 |
Vijayakrishnan S et al. | Solution structure and characterisation of the human pyruvate dehydrogenase complex core assembly. | 2010 | J. Mol. Biol. | pmid:20361979 |
Golas A et al. | Sperm mitochondria diaphorase activity--a gene mapping study of recombinant inbred strains of mice. | 2010 | Int. J. Dev. Biol. | pmid:20209439 |
pmid:20204556 | ||||
pmid:20167543 | ||||
pmid:20159566 | ||||
Goncalves S et al. | Rapid determination of tricarboxylic acid cycle enzyme activities in biological samples. | 2010 | BMC Biochem. | pmid:20109171 |
pmid:20097961 | ||||
pmid:20093189 | ||||
Bryk R et al. | Triazaspirodimethoxybenzoyls as selective inhibitors of mycobacterial lipoamide dehydrogenase . | 2010 | Biochemistry | pmid:20078138 |
pmid:20072824 | ||||
pmid:20059400 | ||||
Oliver HF et al. | Deep RNA sequencing of L. monocytogenes reveals overlapping and extensive stationary phase and sigma B-dependent transcriptomes, including multiple highly transcribed noncoding RNAs. | 2009 | BMC Genomics | pmid:20042087 |
pmid:20036764 | ||||
Bull TJ et al. | A rhodanine agent active against non-replicating intracellular Mycobacterium avium subspecies paratuberculosis. | 2009 | Gut Pathog | pmid:20030828 |
Yin C et al. | Generation and analysis of expression sequence tags from haustoria of the wheat stripe rust fungus Puccinia striiformis f. sp. Tritici. | 2009 | BMC Genomics | pmid:20028560 |
pmid:19877159 | ||||
Wang Q et al. | Genome sequence of the versatile fish pathogen Edwardsiella tarda provides insights into its adaptation to broad host ranges and intracellular niches. | 2009 | PLoS ONE | pmid:19865481 |
Zaman G et al. | Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor alpha and disuse. | 2010 | Bone | pmid:19857613 |
Li J et al. | Pivotal role of the C-terminal DW-motif in mediating inhibition of pyruvate dehydrogenase kinase 2 by dichloroacetate. | 2009 | J. Biol. Chem. | pmid:19833728 |
Spalding MD and Prigge ST | The amidase domain of lipoamidase specifically inactivates lipoylated proteins in vivo. | 2009 | PLoS ONE | pmid:19812687 |
Shen CJ et al. | Proteomic identification of membrane proteins regulating antimicrobial peptide resistance in Vibrio parahaemolyticus. | 2010 | J. Appl. Microbiol. | pmid:19796120 |
pmid:19748835 | ||||
Charles RC et al. | Comparative proteomic analysis of the PhoP regulon in Salmonella enterica serovar Typhi versus Typhimurium. | 2009 | PLoS ONE | pmid:19746165 |
Ndifon W et al. | On the accessibility of adaptive phenotypes of a bacterial metabolic network. | 2009 | PLoS Comput. Biol. | pmid:19696877 |
Wu TF et al. | Proteomic investigation of the impact of oxygen on the protein profiles of hyaluronic acid-producing Streptococcus zooepidemicus. | 2009 | Proteomics | pmid:19688725 |
pmid:19635488 | ||||
pmid:19622241 | ||||
Hohenester S et al. | Primary biliary cirrhosis. | 2009 | Semin Immunopathol | pmid:19603170 |
Matthews RG | A love affair with vitamins. | 2009 | J. Biol. Chem. | pmid:19596855 |
pmid:19582716 | ||||
Johnson M et al. | Maternal enzyme masks the phenotype of mouse embryos lacking dihydrolipoamide dehydrogenase. | 2009 | Reprod. Biomed. Online | pmid:19573295 |
Gerards M et al. | Defective complex I assembly due to C20orf7 mutations as a new cause of Leigh syndrome. | 2010 | J. Med. Genet. | pmid:19542079 |
Li BW et al. | Transcriptomes and pathways associated with infectivity, survival and immunogenicity in Brugia malayi L3. | 2009 | BMC Genomics | pmid:19527522 |
Ajith VK and Prasad R | A novel protein that binds to dnrN-dnrO intergenic region of Streptomyces peucetius purified by DNA affinity capture has dihydrolipoamide dehydrogenase activity. | 2009 | Protein Expr. Purif. | pmid:19481152 |
Xie L et al. | A unified statistical model to support local sequence order independent similarity searching for ligand-binding sites and its application to genome-based drug discovery. | 2009 | Bioinformatics | pmid:19478004 |
Xiao Z et al. | Acetoin catabolism and acetylbutanediol formation by Bacillus pumilus in a chemically defined medium. | 2009 | PLoS ONE | pmid:19461961 |
pmid:19460292 | ||||
Günther S et al. | Knockout studies reveal an important role of Plasmodium lipoic acid protein ligase A1 for asexual blood stage parasite survival. | 2009 | PLoS ONE | pmid:19434237 |
Stern JM et al. | Radiofrequency ablation of small renal cortical tumours in healthy adults: renal function preservation and intermediate oncological outcome. | 2009 | BJU Int. | pmid:19426196 |
Marino SM and Gladyshev VN | A structure-based approach for detection of thiol oxidoreductases and their catalytic redox-active cysteine residues. | 2009 | PLoS Comput. Biol. | pmid:19424433 |
Kurakin A | Scale-free flow of life: on the biology, economics, and physics of the cell. | 2009 | Theor Biol Med Model | pmid:19416527 |
Ambrus A et al. | Inhibition of the alpha-ketoglutarate dehydrogenase-mediated reactive oxygen species generation by lipoic acid. | 2009 | J. Neurochem. | pmid:19393031 |
Tyagi TK et al. | Moonlighting protein in Starkeyomyces koorchalomoides: characterization of dihydrolipoamide dehydrogenase as a protein acetyltransferase utilizing acetoxycoumarin as the acetyl group donor. | 2009 | Biochimie | pmid:19383527 |
White JR et al. | Statistical methods for detecting differentially abundant features in clinical metagenomic samples. | 2009 | PLoS Comput. Biol. | pmid:19360128 |
Yan LJ and Forster MJ | Resolving mitochondrial protein complexes using nongradient blue native polyacrylamide gel electrophoresis. | 2009 | Anal. Biochem. | pmid:19348780 |
Griffin JL and Des Rosiers C | Applications of metabolomics and proteomics to the mdx mouse model of Duchenne muscular dystrophy: lessons from downstream of the transcriptome. | 2009 | Genome Med | pmid:19341503 |
Chi F et al. | Identification of IbeR as a stationary-phase regulator in meningitic Escherichia coli K1 that carries a loss-of-function mutation in rpoS. | 2009 | J. Biomed. Biotechnol. | pmid:19300523 |
pmid:19288589 | ||||
Keyes BE and Burke DJ | Irc15 Is a microtubule-associated protein that regulates microtubule dynamics in Saccharomyces cerevisiae. | 2009 | Curr. Biol. | pmid:19285398 |
Brautigam CA et al. | Subunit and catalytic component stoichiometries of an in vitro reconstituted human pyruvate dehydrogenase complex. | 2009 | J. Biol. Chem. | pmid:19240034 |
Schriek S et al. | Detection of an L-amino acid dehydrogenase activity in Synechocystis sp. PCC 6803. | 2009 | J. Exp. Bot. | pmid:19213808 |
Xi Y et al. | Analysis on relationship between extreme pathways and correlated reaction sets. | 2009 | BMC Bioinformatics | pmid:19208161 |