MeSH term | MeSH ID | Detail |
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Parkinsonian Disorders | D020734 | 20 associated lipids |
Dihydrolipoamide is a lipid of Fatty Acyls (FA) class. Dihydrolipoamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Citric Acid Cycle, Electron Transport, NADH oxidation, Oxidation and Oxidants. Dihydrolipoamide often locates in Mitochondria, Mitochondrial matrix and Chloroplasts. The associated genes with Dihydrolipoamide are Mutant Proteins, Recombinant Proteins, mycothione reductase, Genes, Mitochondrial and alanylproline.
To understand associated biological information of Dihydrolipoamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Dihydrolipoamide is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Dihydrolipoamide
MeSH term | MeSH ID | Detail |
---|---|---|
Parkinsonian Disorders | D020734 | 20 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Campanucci VA et al. | A novel O2-sensing mechanism in rat glossopharyngeal neurones mediated by a halothane-inhibitable background K+ conductance. | 2003 | J. Physiol. (Lond.) | pmid:12640017 |
Petrat F et al. | Reduction of Fe(III) ions complexed to physiological ligands by lipoyl dehydrogenase and other flavoenzymes in vitro: implications for an enzymatic reduction of Fe(III) ions of the labile iron pool. | 2003 | J. Biol. Chem. | pmid:12963736 |
Araújo EJ et al. | Effect of protein and vitamin B deficiency on the morpho-quantitative aspects of the myenteric plexus of the descending colon of adult rats. | 2003 | Arq Neuropsiquiatr | pmid:12806501 |
Argyrou A et al. | Catalysis of diaphorase reactions by Mycobacterium tuberculosis lipoamide dehydrogenase occurs at the EH4 level. | 2003 | Biochemistry | pmid:12590611 |
Shaco-Levy R et al. | On appropriate pathology for photothermal surgery. | 2004 | Lasers Surg Med | pmid:15278925 |
Starkov AA et al. | Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species. | 2004 | J. Neurosci. | pmid:15356189 |
Geisler DA et al. | Antimycin A treatment decreases respiratory internal rotenone-insensitive NADH oxidation capacity in potato leaves. | 2004 | BMC Plant Biol. | pmid:15140267 |
Rani K et al. | Measurement of bile acid in serum and bile with arylamine-glass-bound 3alpha-hydroxysteroid dehydrogenase and diaphorase. | 2004 | Anal. Biochem. | pmid:15301946 |
Kozlov G et al. | Structure of GlgS from Escherichia coli suggests a role in protein-protein interactions. | 2004 | BMC Biol. | pmid:15161493 |
Foster MW and Stamler JS | New insights into protein S-nitrosylation. Mitochondria as a model system. | 2004 | J. Biol. Chem. | pmid:15069080 |
Klivenyi P et al. | Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity. | 2004 | J. Neurochem. | pmid:15009635 |
Leichert LI and Jakob U | Protein thiol modifications visualized in vivo. | 2004 | PLoS Biol. | pmid:15502869 |
Argyrou A et al. | Characterization of a new member of the flavoprotein disulfide reductase family of enzymes from Mycobacterium tuberculosis. | 2004 | J. Biol. Chem. | pmid:15456792 |
Igamberdiev AU et al. | Dihydrolipoamide dehydrogenase from porcine heart catalyzes NADH-dependent scavenging of nitric oxide. | 2004 | FEBS Lett. | pmid:15196936 |
Rocheleau JV et al. | Quantitative NAD(P)H/flavoprotein autofluorescence imaging reveals metabolic mechanisms of pancreatic islet pyruvate response. | 2004 | J. Biol. Chem. | pmid:15148320 |
Hiromasa Y et al. | Organization of the cores of the mammalian pyruvate dehydrogenase complex formed by E2 and E2 plus the E3-binding protein and their capacities to bind the E1 and E3 components. | 2004 | J. Biol. Chem. | pmid:14638692 |
MacDonald MJ et al. | Immunochemical identification of coenzyme Q0-dihydrolipoamide adducts in the E2 components of the alpha-ketoglutarate and pyruvate dehydrogenase complexes partially explains the cellular toxicity of coenzyme Q0. | 2004 | J. Biol. Chem. | pmid:15075342 |
McMillan PJ et al. | The human malaria parasite Plasmodium falciparum possesses two distinct dihydrolipoamide dehydrogenases. | 2005 | Mol. Microbiol. | pmid:15612914 |
Mersey BD et al. | Human microRNA (miR29b) expression controls the amount of branched chain alpha-ketoacid dehydrogenase complex in a cell. | 2005 | Hum. Mol. Genet. | pmid:16203741 |
Odièvre MH et al. | A novel mutation in the dihydrolipoamide dehydrogenase E3 subunit gene (DLD) resulting in an atypical form of alpha-ketoglutarate dehydrogenase deficiency. | 2005 | Hum. Mutat. | pmid:15712224 |
Brautigam CA et al. | Crystal structure of human dihydrolipoamide dehydrogenase: NAD+/NADH binding and the structural basis of disease-causing mutations. | 2005 | J. Mol. Biol. | pmid:15946682 |
Sengupta J et al. | Nitric oxide in blastocyst implantation in the rhesus monkey. | 2005 | Reproduction | pmid:16123239 |
Salcedo E et al. | A glycine-cleavage complex as part of the folate one-carbon metabolism of Plasmodium falciparum. | 2005 | Trends Parasitol. | pmid:16039160 |
Da Sylva TR et al. | Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes. | 2005 | Arthritis Res. Ther. | pmid:15987486 |
Vernon SD and Reeves WC | Evaluation of autoantibodies to common and neuronal cell antigens in Chronic Fatigue Syndrome. | 2005 | J Autoimmune Dis | pmid:15916704 |
Mitra K et al. | Novelty of the pyruvate metabolic enzyme dihydrolipoamide dehydrogenase in spermatozoa: correlation of its localization, tyrosine phosphorylation, and activity during sperm capacitation. | 2005 | J. Biol. Chem. | pmid:15888450 |
Sauer SW et al. | Bioenergetics in glutaryl-coenzyme A dehydrogenase deficiency: a role for glutaryl-coenzyme A. | 2005 | J. Biol. Chem. | pmid:15840571 |
Li XJ et al. | Crucial role of two potential cytosolic regions of Nox2, 191TSSTKTIRRS200 and 484DESQANHFAVHHDEEKD500, on NADPH oxidase activation. | 2005 | J. Biol. Chem. | pmid:15684431 |
Wang W et al. | Proteome analysis of a recombinant Bacillus megaterium strain during heterologous production of a glucosyltransferase. | 2005 | Proteome Sci | pmid:15927046 |
Rajashankar KR et al. | Crystal structure and functional analysis of lipoamide dehydrogenase from Mycobacterium tuberculosis. | 2005 | J. Biol. Chem. | pmid:16093239 |
Tian J et al. | Mycobacterium tuberculosis appears to lack alpha-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes. | 2005 | Mol. Microbiol. | pmid:16045627 |
Klyachko NL et al. | pH-dependent substrate preference of pig heart lipoamide dehydrogenase varies with oligomeric state: response to mitochondrial matrix acidification. | 2005 | J. Biol. Chem. | pmid:15710613 |
Deres P et al. | Prevention of doxorubicin-induced acute cardiotoxicity by an experimental antioxidant compound. | 2005 | J. Cardiovasc. Pharmacol. | pmid:15613977 |
Lee EH et al. | A Korean female patient with thiamine-responsive pyruvate dehydrogenase complex deficiency due to a novel point mutation (Y161C)in the PDHA1 gene. | 2006 | J. Korean Med. Sci. | pmid:17043409 |
Hussain SN et al. | Modifications of proteins by 4-hydroxy-2-nonenal in the ventilatory muscles of rats. | 2006 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:16603597 |
Roy G and Mugesh G | Bioinorganic chemistry in thyroid gland: effect of antithyroid drugs on peroxidase-catalyzed oxidation and iodination reactions. | 2006 | Bioinorg Chem Appl | pmid:17497002 |
Mongodin EF et al. | Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1. | 2006 | PLoS Genet. | pmid:17194220 |
Mukherjee M et al. | Proteins of the glycine decarboxylase complex in the hydrogenosome of Trichomonas vaginalis. | 2006 | Eukaryotic Cell | pmid:17158739 |
Kunieda T et al. | Carbohydrate metabolism genes and pathways in insects: insights from the honey bee genome. | 2006 | Insect Mol. Biol. | pmid:17069632 |
Liu DQ et al. | [Microwave coagulation at different temperatures for hepatocellular carcinoma management: efficacy evaluation by enzyme histochemical staining]. | 2006 | Nan Fang Yi Ke Da Xue Xue Bao | pmid:16939906 |
Brown RM et al. | Pyruvate dehydrogenase E3 binding protein (protein X) deficiency. | 2006 | Dev Med Child Neurol | pmid:16904023 |
Bunik VI et al. | Brain pyruvate and 2-oxoglutarate dehydrogenase complexes are mitochondrial targets of the CoA ester of the Refsum disease marker phytanic acid. | 2006 | FEBS Lett. | pmid:16737698 |
Lee H et al. | An integrated approach to the prediction of domain-domain interactions. | 2006 | BMC Bioinformatics | pmid:16725050 |
Smolle M et al. | A new level of architectural complexity in the human pyruvate dehydrogenase complex. | 2006 | J. Biol. Chem. | pmid:16679318 |
Vasiliou V et al. | Update of the NAD(P)H:quinone oxidoreductase (NQO) gene family. | 2006 | Hum. Genomics | pmid:16595077 |
Brautigam CA et al. | Structural insight into interactions between dihydrolipoamide dehydrogenase (E3) and E3 binding protein of human pyruvate dehydrogenase complex. | 2006 | Structure | pmid:16442803 |
Ciszak EM et al. | How dihydrolipoamide dehydrogenase-binding protein binds dihydrolipoamide dehydrogenase in the human pyruvate dehydrogenase complex. | 2006 | J. Biol. Chem. | pmid:16263718 |
Boucher IW et al. | Structural and biochemical characterization of a mitochondrial peroxiredoxin from Plasmodium falciparum. | 2006 | Mol. Microbiol. | pmid:16879648 |
Kato M et al. | A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex. | 2006 | EMBO J. | pmid:17124494 |
Li M et al. | Effect of lpdA gene knockout on the metabolism in Escherichia coli based on enzyme activities, intracellular metabolite concentrations and metabolic flux analysis by 13C-labeling experiments. | 2006 | J. Biotechnol. | pmid:16310273 |
Yang L et al. | BMDExpress: a software tool for the benchmark dose analyses of genomic data. | 2007 | BMC Genomics | pmid:17961223 |
Brown SE et al. | Targeting lipoic acid to mitochondria: synthesis and characterization of a triphenylphosphonium-conjugated alpha-lipoyl derivative. | 2007 | Free Radic. Biol. Med. | pmid:17512456 |
Yan LJ et al. | Histochemical staining and quantification of dihydrolipoamide dehydrogenase diaphorase activity using blue native PAGE. | 2007 | Electrophoresis | pmid:17315258 |
Alvaro D et al. | Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. | 2007 | PLoS Genet. | pmid:18085829 |
Jackson AP | Evolutionary consequences of a large duplication event in Trypanosoma brucei: chromosomes 4 and 8 are partial duplicons. | 2007 | BMC Genomics | pmid:18036214 |
Coker JA and DasSarma S | Genetic and transcriptomic analysis of transcription factor genes in the model halophilic Archaeon: coordinate action of TbpD and TfbA. | 2007 | BMC Genet. | pmid:17892563 |
Marques B et al. | Liposome-mediated cellular delivery of active gp91(phox). | 2007 | PLoS ONE | pmid:17848987 |
Heinicke S et al. | The Princeton Protein Orthology Database (P-POD): a comparative genomics analysis tool for biologists. | 2007 | PLoS ONE | pmid:17712414 |
LuÃs PB et al. | Valproic acid metabolites inhibit dihydrolipoyl dehydrogenase activity leading to impaired 2-oxoglutarate-driven oxidative phosphorylation. | 2007 | Biochim. Biophys. Acta | pmid:17706936 |
Liberti EA et al. | Effects of combined pre- and post-natal protein deprivation on the myenteric plexus of the esophagus of weanling rats: a histochemical, quantitative and ultrastructural study. | 2007 | World J. Gastroenterol. | pmid:17659710 |
Vilei EM et al. | Beta-D-glucoside utilization by Mycoplasma mycoides subsp. mycoides SC: possible involvement in the control of cytotoxicity towards bovine lung cells. | 2007 | BMC Microbiol. | pmid:17439646 |
Islam MM et al. | A novel branched-chain amino acid metabolon. Protein-protein interactions in a supramolecular complex. | 2007 | J. Biol. Chem. | pmid:17314104 |
Pino P et al. | Dual targeting of antioxidant and metabolic enzymes to the mitochondrion and the apicoplast of Toxoplasma gondii. | 2007 | PLoS Pathog. | pmid:17784785 |
Günther S et al. | Apicoplast lipoic acid protein ligase B is not essential for Plasmodium falciparum. | 2007 | PLoS Pathog. | pmid:18069893 |
Mochel F et al. | Early energy deficit in Huntington disease: identification of a plasma biomarker traceable during disease progression. | 2007 | PLoS ONE | pmid:17653274 |
Chiu KP et al. | Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes. | 2007 | BMC Cancer | pmid:17594473 |
HÃ¥kansson AP and Smith AW | Enzymatic characterization of dihydrolipoamide dehydrogenase from Streptococcus pneumoniae harboring its own substrate. | 2007 | J. Biol. Chem. | pmid:17690105 |
Ojha S et al. | Evolution of function in the "two dinucleotide binding domains" flavoproteins. | 2007 | PLoS Comput. Biol. | pmid:17658942 |
Deghmane AE et al. | Lipoamide dehydrogenase mediates retention of coronin-1 on BCG vacuoles, leading to arrest in phagosome maturation. | 2007 | J. Cell. Sci. | pmid:17652161 |
Takahashi T et al. | NADPH-dependent coenzyme Q reductase is the main enzyme responsible for the reduction of non-mitochondrial CoQ in cells. | 2008 | Biofactors | pmid:19096101 |
Gómez-Baena G et al. | Glucose uptake and its effect on gene expression in prochlorococcus. | 2008 | PLoS ONE | pmid:18941506 |
Min CK et al. | Genome-based construction of the metabolic pathways of Orientia tsutsugamushi and comparative analysis within the Rickettsiales order. | 2008 | Comp. Funct. Genomics | pmid:18528528 |
Vasquez-Robinet C et al. | Physiological and molecular adaptations to drought in Andean potato genotypes. | 2008 | J. Exp. Bot. | pmid:18535297 |
Calingasan NY et al. | Influence of mitochondrial enzyme deficiency on adult neurogenesis in mouse models of neurodegenerative diseases. | 2008 | Neuroscience | pmid:18423880 |
Jiang ZD and Wen YH | [Expressions of c-Fos and NADPH-d in the related brainstem during vestibular compensation]. | 2008 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:19180910 |
Jaleel A et al. | In vivo measurement of synthesis rate of individual skeletal muscle mitochondrial proteins. | 2008 | Am. J. Physiol. Endocrinol. Metab. | pmid:18765679 |
Norton GJ et al. | Rice-arsenate interactions in hydroponics: whole genome transcriptional analysis. | 2008 | J. Exp. Bot. | pmid:18453530 |
Vyas PM and Payne RM | TAT opens the door. | 2008 | Mol. Ther. | pmid:18362922 |
Stensballe A et al. | The amyloplast proteome of potato tuber. | 2008 | FEBS J. | pmid:18331355 |
Yan LJ et al. | Changes in dihydrolipoamide dehydrogenase expression and activity during postnatal development and aging in the rat brain. | 2008 | Mech. Ageing Dev. | pmid:18316113 |
Batista AP et al. | The dihydrolipoamide dehydrogenase from the crenarchaeon Acidianus ambivalens. | 2008 | FEMS Microbiol. Lett. | pmid:18312361 |
Mary-Huard T et al. | Statistical methodology for the analysis of dye-switch microarray experiments. | 2008 | BMC Bioinformatics | pmid:18271965 |
Opperman DJ and van Heerden E | A membrane-associated protein with Cr(VI)-reducing activity from Thermus scotoductus SA-01. | 2008 | FEMS Microbiol. Lett. | pmid:18218019 |
Li M et al. | AI-2-dependent gene regulation in Staphylococcus epidermidis. | 2008 | BMC Microbiol. | pmid:18182108 |
Rodrigues DF et al. | Architecture of thermal adaptation in an Exiguobacterium sibiricum strain isolated from 3 million year old permafrost: a genome and transcriptome approach. | 2008 | BMC Genomics | pmid:19019206 |
Chakraborty S et al. | Characterization of a dihydrolipoyl dehydrogenase having diaphorase activity of Clostridium kluyveri. | 2008 | Biosci. Biotechnol. Biochem. | pmid:18391450 |
Rapoport M et al. | TAT-mediated delivery of LAD restores pyruvate dehydrogenase complex activity in the mitochondria of patients with LAD deficiency. | 2008 | Mol. Ther. | pmid:18362926 |
de Berardinis V et al. | A complete collection of single-gene deletion mutants of Acinetobacter baylyi ADP1. | 2008 | Mol. Syst. Biol. | pmid:18319726 |
Yukumi S et al. | Feasibility of induction heating using a sintered MgFe2O4 needle for minimally invasive breast cancer therapy. | 2008 Jan-Feb | Anticancer Res. | pmid:18383826 |
Ajith VK and Prasad R | A novel protein that binds to dnrN-dnrO intergenic region of Streptomyces peucetius purified by DNA affinity capture has dihydrolipoamide dehydrogenase activity. | 2009 | Protein Expr. Purif. | pmid:19481152 |
Oliver HF et al. | Deep RNA sequencing of L. monocytogenes reveals overlapping and extensive stationary phase and sigma B-dependent transcriptomes, including multiple highly transcribed noncoding RNAs. | 2009 | BMC Genomics | pmid:20042087 |
Schriek S et al. | Detection of an L-amino acid dehydrogenase activity in Synechocystis sp. PCC 6803. | 2009 | J. Exp. Bot. | pmid:19213808 |
Bull TJ et al. | A rhodanine agent active against non-replicating intracellular Mycobacterium avium subspecies paratuberculosis. | 2009 | Gut Pathog | pmid:20030828 |
Keyes BE and Burke DJ | Irc15 Is a microtubule-associated protein that regulates microtubule dynamics in Saccharomyces cerevisiae. | 2009 | Curr. Biol. | pmid:19285398 |
Lee HM et al. | Impaired mitochondrial respiration and protein nitration in the rat hippocampus after acute inhalation of combustion smoke. | 2009 | Toxicol. Appl. Pharmacol. | pmid:19133281 |
Laia ML et al. | New genes of Xanthomonas citri subsp. citri involved in pathogenesis and adaptation revealed by a transposon-based mutant library. | 2009 | BMC Microbiol. | pmid:19149882 |
Brautigam CA et al. | Subunit and catalytic component stoichiometries of an in vitro reconstituted human pyruvate dehydrogenase complex. | 2009 | J. Biol. Chem. | pmid:19240034 |
Xi Y et al. | Analysis on relationship between extreme pathways and correlated reaction sets. | 2009 | BMC Bioinformatics | pmid:19208161 |
Chi F et al. | Identification of IbeR as a stationary-phase regulator in meningitic Escherichia coli K1 that carries a loss-of-function mutation in rpoS. | 2009 | J. Biomed. Biotechnol. | pmid:19300523 |
Tyagi TK et al. | Moonlighting protein in Starkeyomyces koorchalomoides: characterization of dihydrolipoamide dehydrogenase as a protein acetyltransferase utilizing acetoxycoumarin as the acetyl group donor. | 2009 | Biochimie | pmid:19383527 |