Dihydrolipoamide

Dihydrolipoamide is a lipid of Fatty Acyls (FA) class. Dihydrolipoamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Citric Acid Cycle, Electron Transport, NADH oxidation, Oxidation and Oxidants. Dihydrolipoamide often locates in Mitochondria, Mitochondrial matrix and Chloroplasts. The associated genes with Dihydrolipoamide are Mutant Proteins, Recombinant Proteins, mycothione reductase, Genes, Mitochondrial and alanylproline.

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Introduction

To understand associated biological information of Dihydrolipoamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Dihydrolipoamide?

Dihydrolipoamide is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Dihydrolipoamide

MeSH term MeSH ID Detail
Parkinsonian Disorders D020734 20 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Dihydrolipoamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with Dihydrolipoamide?

Related references are published most in these journals:

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What functions are associated with Dihydrolipoamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Dihydrolipoamide?

There are no associated biomedical information in the current reference collection.

What genes are associated with Dihydrolipoamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Dihydrolipoamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Dihydrolipoamide

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Authors Title Published Journal PubMed Link
Campanucci VA et al. A novel O2-sensing mechanism in rat glossopharyngeal neurones mediated by a halothane-inhibitable background K+ conductance. 2003 J. Physiol. (Lond.) pmid:12640017
Petrat F et al. Reduction of Fe(III) ions complexed to physiological ligands by lipoyl dehydrogenase and other flavoenzymes in vitro: implications for an enzymatic reduction of Fe(III) ions of the labile iron pool. 2003 J. Biol. Chem. pmid:12963736
Araújo EJ et al. Effect of protein and vitamin B deficiency on the morpho-quantitative aspects of the myenteric plexus of the descending colon of adult rats. 2003 Arq Neuropsiquiatr pmid:12806501
Argyrou A et al. Catalysis of diaphorase reactions by Mycobacterium tuberculosis lipoamide dehydrogenase occurs at the EH4 level. 2003 Biochemistry pmid:12590611
Shaco-Levy R et al. On appropriate pathology for photothermal surgery. 2004 Lasers Surg Med pmid:15278925
Starkov AA et al. Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species. 2004 J. Neurosci. pmid:15356189
Geisler DA et al. Antimycin A treatment decreases respiratory internal rotenone-insensitive NADH oxidation capacity in potato leaves. 2004 BMC Plant Biol. pmid:15140267
Rani K et al. Measurement of bile acid in serum and bile with arylamine-glass-bound 3alpha-hydroxysteroid dehydrogenase and diaphorase. 2004 Anal. Biochem. pmid:15301946
Kozlov G et al. Structure of GlgS from Escherichia coli suggests a role in protein-protein interactions. 2004 BMC Biol. pmid:15161493
Foster MW and Stamler JS New insights into protein S-nitrosylation. Mitochondria as a model system. 2004 J. Biol. Chem. pmid:15069080
Klivenyi P et al. Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity. 2004 J. Neurochem. pmid:15009635
Leichert LI and Jakob U Protein thiol modifications visualized in vivo. 2004 PLoS Biol. pmid:15502869
Argyrou A et al. Characterization of a new member of the flavoprotein disulfide reductase family of enzymes from Mycobacterium tuberculosis. 2004 J. Biol. Chem. pmid:15456792
Igamberdiev AU et al. Dihydrolipoamide dehydrogenase from porcine heart catalyzes NADH-dependent scavenging of nitric oxide. 2004 FEBS Lett. pmid:15196936
Rocheleau JV et al. Quantitative NAD(P)H/flavoprotein autofluorescence imaging reveals metabolic mechanisms of pancreatic islet pyruvate response. 2004 J. Biol. Chem. pmid:15148320
Hiromasa Y et al. Organization of the cores of the mammalian pyruvate dehydrogenase complex formed by E2 and E2 plus the E3-binding protein and their capacities to bind the E1 and E3 components. 2004 J. Biol. Chem. pmid:14638692
MacDonald MJ et al. Immunochemical identification of coenzyme Q0-dihydrolipoamide adducts in the E2 components of the alpha-ketoglutarate and pyruvate dehydrogenase complexes partially explains the cellular toxicity of coenzyme Q0. 2004 J. Biol. Chem. pmid:15075342
McMillan PJ et al. The human malaria parasite Plasmodium falciparum possesses two distinct dihydrolipoamide dehydrogenases. 2005 Mol. Microbiol. pmid:15612914
Mersey BD et al. Human microRNA (miR29b) expression controls the amount of branched chain alpha-ketoacid dehydrogenase complex in a cell. 2005 Hum. Mol. Genet. pmid:16203741
Odièvre MH et al. A novel mutation in the dihydrolipoamide dehydrogenase E3 subunit gene (DLD) resulting in an atypical form of alpha-ketoglutarate dehydrogenase deficiency. 2005 Hum. Mutat. pmid:15712224
Brautigam CA et al. Crystal structure of human dihydrolipoamide dehydrogenase: NAD+/NADH binding and the structural basis of disease-causing mutations. 2005 J. Mol. Biol. pmid:15946682
Sengupta J et al. Nitric oxide in blastocyst implantation in the rhesus monkey. 2005 Reproduction pmid:16123239
Salcedo E et al. A glycine-cleavage complex as part of the folate one-carbon metabolism of Plasmodium falciparum. 2005 Trends Parasitol. pmid:16039160
Da Sylva TR et al. Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes. 2005 Arthritis Res. Ther. pmid:15987486
Vernon SD and Reeves WC Evaluation of autoantibodies to common and neuronal cell antigens in Chronic Fatigue Syndrome. 2005 J Autoimmune Dis pmid:15916704
Mitra K et al. Novelty of the pyruvate metabolic enzyme dihydrolipoamide dehydrogenase in spermatozoa: correlation of its localization, tyrosine phosphorylation, and activity during sperm capacitation. 2005 J. Biol. Chem. pmid:15888450
Sauer SW et al. Bioenergetics in glutaryl-coenzyme A dehydrogenase deficiency: a role for glutaryl-coenzyme A. 2005 J. Biol. Chem. pmid:15840571
Li XJ et al. Crucial role of two potential cytosolic regions of Nox2, 191TSSTKTIRRS200 and 484DESQANHFAVHHDEEKD500, on NADPH oxidase activation. 2005 J. Biol. Chem. pmid:15684431
Wang W et al. Proteome analysis of a recombinant Bacillus megaterium strain during heterologous production of a glucosyltransferase. 2005 Proteome Sci pmid:15927046
Rajashankar KR et al. Crystal structure and functional analysis of lipoamide dehydrogenase from Mycobacterium tuberculosis. 2005 J. Biol. Chem. pmid:16093239
Tian J et al. Mycobacterium tuberculosis appears to lack alpha-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes. 2005 Mol. Microbiol. pmid:16045627
Klyachko NL et al. pH-dependent substrate preference of pig heart lipoamide dehydrogenase varies with oligomeric state: response to mitochondrial matrix acidification. 2005 J. Biol. Chem. pmid:15710613
Deres P et al. Prevention of doxorubicin-induced acute cardiotoxicity by an experimental antioxidant compound. 2005 J. Cardiovasc. Pharmacol. pmid:15613977
Lee EH et al. A Korean female patient with thiamine-responsive pyruvate dehydrogenase complex deficiency due to a novel point mutation (Y161C)in the PDHA1 gene. 2006 J. Korean Med. Sci. pmid:17043409
Hussain SN et al. Modifications of proteins by 4-hydroxy-2-nonenal in the ventilatory muscles of rats. 2006 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:16603597
Roy G and Mugesh G Bioinorganic chemistry in thyroid gland: effect of antithyroid drugs on peroxidase-catalyzed oxidation and iodination reactions. 2006 Bioinorg Chem Appl pmid:17497002
Mongodin EF et al. Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1. 2006 PLoS Genet. pmid:17194220
Mukherjee M et al. Proteins of the glycine decarboxylase complex in the hydrogenosome of Trichomonas vaginalis. 2006 Eukaryotic Cell pmid:17158739
Kunieda T et al. Carbohydrate metabolism genes and pathways in insects: insights from the honey bee genome. 2006 Insect Mol. Biol. pmid:17069632
Liu DQ et al. [Microwave coagulation at different temperatures for hepatocellular carcinoma management: efficacy evaluation by enzyme histochemical staining]. 2006 Nan Fang Yi Ke Da Xue Xue Bao pmid:16939906
Brown RM et al. Pyruvate dehydrogenase E3 binding protein (protein X) deficiency. 2006 Dev Med Child Neurol pmid:16904023
Bunik VI et al. Brain pyruvate and 2-oxoglutarate dehydrogenase complexes are mitochondrial targets of the CoA ester of the Refsum disease marker phytanic acid. 2006 FEBS Lett. pmid:16737698
Lee H et al. An integrated approach to the prediction of domain-domain interactions. 2006 BMC Bioinformatics pmid:16725050
Smolle M et al. A new level of architectural complexity in the human pyruvate dehydrogenase complex. 2006 J. Biol. Chem. pmid:16679318
Vasiliou V et al. Update of the NAD(P)H:quinone oxidoreductase (NQO) gene family. 2006 Hum. Genomics pmid:16595077
Brautigam CA et al. Structural insight into interactions between dihydrolipoamide dehydrogenase (E3) and E3 binding protein of human pyruvate dehydrogenase complex. 2006 Structure pmid:16442803
Ciszak EM et al. How dihydrolipoamide dehydrogenase-binding protein binds dihydrolipoamide dehydrogenase in the human pyruvate dehydrogenase complex. 2006 J. Biol. Chem. pmid:16263718
Boucher IW et al. Structural and biochemical characterization of a mitochondrial peroxiredoxin from Plasmodium falciparum. 2006 Mol. Microbiol. pmid:16879648
Kato M et al. A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex. 2006 EMBO J. pmid:17124494
Li M et al. Effect of lpdA gene knockout on the metabolism in Escherichia coli based on enzyme activities, intracellular metabolite concentrations and metabolic flux analysis by 13C-labeling experiments. 2006 J. Biotechnol. pmid:16310273
Yang L et al. BMDExpress: a software tool for the benchmark dose analyses of genomic data. 2007 BMC Genomics pmid:17961223
Brown SE et al. Targeting lipoic acid to mitochondria: synthesis and characterization of a triphenylphosphonium-conjugated alpha-lipoyl derivative. 2007 Free Radic. Biol. Med. pmid:17512456
Yan LJ et al. Histochemical staining and quantification of dihydrolipoamide dehydrogenase diaphorase activity using blue native PAGE. 2007 Electrophoresis pmid:17315258
Alvaro D et al. Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. 2007 PLoS Genet. pmid:18085829
Jackson AP Evolutionary consequences of a large duplication event in Trypanosoma brucei: chromosomes 4 and 8 are partial duplicons. 2007 BMC Genomics pmid:18036214
Coker JA and DasSarma S Genetic and transcriptomic analysis of transcription factor genes in the model halophilic Archaeon: coordinate action of TbpD and TfbA. 2007 BMC Genet. pmid:17892563
Marques B et al. Liposome-mediated cellular delivery of active gp91(phox). 2007 PLoS ONE pmid:17848987
Heinicke S et al. The Princeton Protein Orthology Database (P-POD): a comparative genomics analysis tool for biologists. 2007 PLoS ONE pmid:17712414
Luís PB et al. Valproic acid metabolites inhibit dihydrolipoyl dehydrogenase activity leading to impaired 2-oxoglutarate-driven oxidative phosphorylation. 2007 Biochim. Biophys. Acta pmid:17706936
Liberti EA et al. Effects of combined pre- and post-natal protein deprivation on the myenteric plexus of the esophagus of weanling rats: a histochemical, quantitative and ultrastructural study. 2007 World J. Gastroenterol. pmid:17659710
Vilei EM et al. Beta-D-glucoside utilization by Mycoplasma mycoides subsp. mycoides SC: possible involvement in the control of cytotoxicity towards bovine lung cells. 2007 BMC Microbiol. pmid:17439646
Islam MM et al. A novel branched-chain amino acid metabolon. Protein-protein interactions in a supramolecular complex. 2007 J. Biol. Chem. pmid:17314104
Pino P et al. Dual targeting of antioxidant and metabolic enzymes to the mitochondrion and the apicoplast of Toxoplasma gondii. 2007 PLoS Pathog. pmid:17784785
Günther S et al. Apicoplast lipoic acid protein ligase B is not essential for Plasmodium falciparum. 2007 PLoS Pathog. pmid:18069893
Mochel F et al. Early energy deficit in Huntington disease: identification of a plasma biomarker traceable during disease progression. 2007 PLoS ONE pmid:17653274
Chiu KP et al. Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes. 2007 BMC Cancer pmid:17594473
HÃ¥kansson AP and Smith AW Enzymatic characterization of dihydrolipoamide dehydrogenase from Streptococcus pneumoniae harboring its own substrate. 2007 J. Biol. Chem. pmid:17690105
Ojha S et al. Evolution of function in the "two dinucleotide binding domains" flavoproteins. 2007 PLoS Comput. Biol. pmid:17658942
Deghmane AE et al. Lipoamide dehydrogenase mediates retention of coronin-1 on BCG vacuoles, leading to arrest in phagosome maturation. 2007 J. Cell. Sci. pmid:17652161
Takahashi T et al. NADPH-dependent coenzyme Q reductase is the main enzyme responsible for the reduction of non-mitochondrial CoQ in cells. 2008 Biofactors pmid:19096101
Gómez-Baena G et al. Glucose uptake and its effect on gene expression in prochlorococcus. 2008 PLoS ONE pmid:18941506
Min CK et al. Genome-based construction of the metabolic pathways of Orientia tsutsugamushi and comparative analysis within the Rickettsiales order. 2008 Comp. Funct. Genomics pmid:18528528
Vasquez-Robinet C et al. Physiological and molecular adaptations to drought in Andean potato genotypes. 2008 J. Exp. Bot. pmid:18535297
Calingasan NY et al. Influence of mitochondrial enzyme deficiency on adult neurogenesis in mouse models of neurodegenerative diseases. 2008 Neuroscience pmid:18423880
Jiang ZD and Wen YH [Expressions of c-Fos and NADPH-d in the related brainstem during vestibular compensation]. 2008 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:19180910
Jaleel A et al. In vivo measurement of synthesis rate of individual skeletal muscle mitochondrial proteins. 2008 Am. J. Physiol. Endocrinol. Metab. pmid:18765679
Norton GJ et al. Rice-arsenate interactions in hydroponics: whole genome transcriptional analysis. 2008 J. Exp. Bot. pmid:18453530
Vyas PM and Payne RM TAT opens the door. 2008 Mol. Ther. pmid:18362922
Stensballe A et al. The amyloplast proteome of potato tuber. 2008 FEBS J. pmid:18331355
Yan LJ et al. Changes in dihydrolipoamide dehydrogenase expression and activity during postnatal development and aging in the rat brain. 2008 Mech. Ageing Dev. pmid:18316113
Batista AP et al. The dihydrolipoamide dehydrogenase from the crenarchaeon Acidianus ambivalens. 2008 FEMS Microbiol. Lett. pmid:18312361
Mary-Huard T et al. Statistical methodology for the analysis of dye-switch microarray experiments. 2008 BMC Bioinformatics pmid:18271965
Opperman DJ and van Heerden E A membrane-associated protein with Cr(VI)-reducing activity from Thermus scotoductus SA-01. 2008 FEMS Microbiol. Lett. pmid:18218019
Li M et al. AI-2-dependent gene regulation in Staphylococcus epidermidis. 2008 BMC Microbiol. pmid:18182108
Rodrigues DF et al. Architecture of thermal adaptation in an Exiguobacterium sibiricum strain isolated from 3 million year old permafrost: a genome and transcriptome approach. 2008 BMC Genomics pmid:19019206
Chakraborty S et al. Characterization of a dihydrolipoyl dehydrogenase having diaphorase activity of Clostridium kluyveri. 2008 Biosci. Biotechnol. Biochem. pmid:18391450
Rapoport M et al. TAT-mediated delivery of LAD restores pyruvate dehydrogenase complex activity in the mitochondria of patients with LAD deficiency. 2008 Mol. Ther. pmid:18362926
de Berardinis V et al. A complete collection of single-gene deletion mutants of Acinetobacter baylyi ADP1. 2008 Mol. Syst. Biol. pmid:18319726
Yukumi S et al. Feasibility of induction heating using a sintered MgFe2O4 needle for minimally invasive breast cancer therapy. 2008 Jan-Feb Anticancer Res. pmid:18383826
Ajith VK and Prasad R A novel protein that binds to dnrN-dnrO intergenic region of Streptomyces peucetius purified by DNA affinity capture has dihydrolipoamide dehydrogenase activity. 2009 Protein Expr. Purif. pmid:19481152
Oliver HF et al. Deep RNA sequencing of L. monocytogenes reveals overlapping and extensive stationary phase and sigma B-dependent transcriptomes, including multiple highly transcribed noncoding RNAs. 2009 BMC Genomics pmid:20042087
Schriek S et al. Detection of an L-amino acid dehydrogenase activity in Synechocystis sp. PCC 6803. 2009 J. Exp. Bot. pmid:19213808
Bull TJ et al. A rhodanine agent active against non-replicating intracellular Mycobacterium avium subspecies paratuberculosis. 2009 Gut Pathog pmid:20030828
Keyes BE and Burke DJ Irc15 Is a microtubule-associated protein that regulates microtubule dynamics in Saccharomyces cerevisiae. 2009 Curr. Biol. pmid:19285398
Lee HM et al. Impaired mitochondrial respiration and protein nitration in the rat hippocampus after acute inhalation of combustion smoke. 2009 Toxicol. Appl. Pharmacol. pmid:19133281
Laia ML et al. New genes of Xanthomonas citri subsp. citri involved in pathogenesis and adaptation revealed by a transposon-based mutant library. 2009 BMC Microbiol. pmid:19149882
Brautigam CA et al. Subunit and catalytic component stoichiometries of an in vitro reconstituted human pyruvate dehydrogenase complex. 2009 J. Biol. Chem. pmid:19240034
Xi Y et al. Analysis on relationship between extreme pathways and correlated reaction sets. 2009 BMC Bioinformatics pmid:19208161
Chi F et al. Identification of IbeR as a stationary-phase regulator in meningitic Escherichia coli K1 that carries a loss-of-function mutation in rpoS. 2009 J. Biomed. Biotechnol. pmid:19300523
Tyagi TK et al. Moonlighting protein in Starkeyomyces koorchalomoides: characterization of dihydrolipoamide dehydrogenase as a protein acetyltransferase utilizing acetoxycoumarin as the acetyl group donor. 2009 Biochimie pmid:19383527