lysophosphatidic acid

lysophosphatidic acid is a lipid of Glycerophospholipids (GP) class. Lysophosphatidic acid is associated with abnormalities such as Atherosclerosis, Alzheimer's Disease, Asthma, Diabetes Mellitus, Non-Insulin-Dependent and Septicemia. The involved functions are known as Inflammation, Chemotaxis, Binding (Molecular Function), Polymerization and Inflammatory Response. Lysophosphatidic acid often locates in Cytoskeleton, Microfilaments, actin cytoskeleton, Extracellular and Structure of germinal center of lymph node. The associated genes with lysophosphatidic acid are TNF gene, MAPK3 gene, RHOA gene, CDC42 gene and ADRBK1 gene. The related lipids are lysophosphatidic acid, Lipopolysaccharides, Lysophosphatidylcholines, Lysophospholipids and Phosphatidic Acid. The related experimental models are Knock-out, Transgenic Model, Rodent Model and Disease model.

Cross Reference

Introduction

To understand associated biological information of lysophosphatidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lysophosphatidic acid?

lysophosphatidic acid is suspected in Atherosclerosis, Asthma, Dyslipidemias, Acute coronary syndrome, Pulmonary Fibrosis, Atherosclerosis of aorta and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lysophosphatidic acid

MeSH term MeSH ID Detail
Tuberculosis D014376 20 associated lipids
Adenocarcinoma D000230 166 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with lysophosphatidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with lysophosphatidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with lysophosphatidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lysophosphatidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with lysophosphatidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lysophosphatidic acid?

Knock-out

Knock-out are used in the study 'Source and role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosis.' (Navab M et al., 2015) and Knock-out are used in the study 'Lysophospholipid mediators in the vasculature.' (Mueller P et al., 2015).

Transgenic Model

Transgenic Model are used in the study 'Lysophosphatidic acid inhibits CD8 T cell activation and control of tumor progression.' (Oda SK et al., 2013).

Rodent Model

Rodent Model are used in the study 'Lysophosphatidic acid mediates fibrosis in injured joints by regulating collagen type I biosynthesis.' (Wu L et al., 2015).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with lysophosphatidic acid

Download all related citations
Per page 10 20 50 100 | Total 1571
Authors Title Published Journal PubMed Link
Wang J et al. Plasma lipidomic signatures of spontaneous obese rhesus monkeys. 2019 Lipids Health Dis pmid:30621707
Lei L et al. The role of lysophosphatidic acid in the physiology and pathology of the skin. 2019 Life Sci. pmid:30584899
Jing X et al. Proliferation and differentiation of rat adipose‑derived stem cells are regulated by yes‑associated protein. 2018 Int. J. Mol. Med. pmid:29916531
Masago K et al. Lysophosphatidic acid receptor, LPA, regulates endothelial blood-brain barrier function: Implication for hepatic encephalopathy. 2018 Biochem. Biophys. Res. Commun. pmid:29778535
Shen X et al. Lysophosphatidic acid enhances neointimal hyperplasia following vascular injury through modulating proliferation, autophagy, inflammation and oxidative stress. 2018 Mol Med Rep pmid:29749484
Kim EY et al. Serum lipidomic analysis for the discovery of biomarkers for major depressive disorder in drug-free patients. 2018 Psychiatry Res pmid:29719272
Zou W et al. LC-Q-TOF-MS based plasma metabolomic profile of subclinical pelvic inflammatory disease: A pilot study. 2018 Clin. Chim. Acta pmid:29709453
Szepanowski F et al. Lysophosphatidic acid propagates post-injury Schwann cell dedifferentiation through LPA signaling. 2018 Neurosci. Lett. pmid:29051083
Sinderewicz E et al. Bovine ovarian follicular growth and development correlate with lysophosphatidic acid expression. 2018 Theriogenology pmid:29028570
Chandra M et al. Cardiac-specific inactivation of LPP3 in mice leads to myocardial dysfunction and heart failure. 2018 Redox Biol pmid:28982073