| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tuberculosis | D014376 | 20 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pulmonary Fibrosis | D011658 | 24 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetic Retinopathy | D003930 | 39 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
lysophosphatidic acid
lysophosphatidic acid is a lipid of Glycerophospholipids (GP) class. Lysophosphatidic acid is associated with abnormalities such as Atherosclerosis, Alzheimer's Disease, Asthma, Diabetes Mellitus, Non-Insulin-Dependent and Septicemia. The involved functions are known as Inflammation, Chemotaxis, Binding (Molecular Function), Polymerization and Inflammatory Response. Lysophosphatidic acid often locates in Cytoskeleton, Microfilaments, actin cytoskeleton, Extracellular and Structure of germinal center of lymph node. The associated genes with lysophosphatidic acid are TNF gene, MAPK3 gene, RHOA gene, CDC42 gene and ADRBK1 gene. The related lipids are lysophosphatidic acid, Lipopolysaccharides, Lysophosphatidylcholines, Lysophospholipids and Phosphatidic Acid. The related experimental models are Knock-out, Transgenic Model, Rodent Model and Disease model.
Cross Reference
Introduction
To understand associated biological information of lysophosphatidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with lysophosphatidic acid?
lysophosphatidic acid is suspected in Atherosclerosis, Asthma, Dyslipidemias, Acute coronary syndrome, Pulmonary Fibrosis, Atherosclerosis of aorta and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with lysophosphatidic acid
PubChem Associated disorders and diseases
What pathways are associated with lysophosphatidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with lysophosphatidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with lysophosphatidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with lysophosphatidic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with lysophosphatidic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with lysophosphatidic acid?
Knock-out
Knock-out are used in the study 'Source and role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosis.' (Navab M et al., 2015) and Knock-out are used in the study 'Lysophospholipid mediators in the vasculature.' (Mueller P et al., 2015).
Transgenic Model
Transgenic Model are used in the study 'Lysophosphatidic acid inhibits CD8 T cell activation and control of tumor progression.' (Oda SK et al., 2013).
Rodent Model
Rodent Model are used in the study 'Lysophosphatidic acid mediates fibrosis in injured joints by regulating collagen type I biosynthesis.' (Wu L et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with lysophosphatidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Aikawa S et al. | Autotaxin-lysophosphatidic acid-LPA3 signaling at the embryo-epithelial boundary controls decidualization pathways. | 2017 | EMBO J. | pmid:28588064 |
| Yamauchi A et al. | Evaluation of pancreatic cancer cell migration with multiple parameters in vitro by using an optical real-time cell mobility assay device. | 2017 | BMC Cancer | pmid:28359316 |
| Dong Y et al. | Lysophosphatidic Acid Triggers Apoptosis in HeLa Cells through the Upregulation of Tumor Necrosis Factor Receptor Superfamily Member 21. | 2017 | Mediators Inflamm. | pmid:28348459 |
| Cao P et al. | Autocrine lysophosphatidic acid signaling activates β-catenin and promotes lung allograft fibrosis. | 2017 | J. Clin. Invest. | pmid:28240604 |
| Alhmada Y et al. | Hepatitis C virus-associated pruritus: Etiopathogenesis and therapeutic strategies. | 2017 | World J. Gastroenterol. | pmid:28223719 |
| Ray U et al. | Lysophosphatidic Acid Promotes Epithelial to Mesenchymal Transition in Ovarian Cancer Cells by Repressing SIRT1. | 2017 | Cell. Physiol. Biochem. | pmid:28214851 |
| Dong L et al. | Diet-induced obesity links to ER positive breast cancer progression via LPA/PKD-1-CD36 signaling-mediated microvascular remodeling. | 2017 | Oncotarget | pmid:28186980 |
| Tang X et al. | Doxycycline attenuates breast cancer related inflammation by decreasing plasma lysophosphatidate concentrations and inhibiting NF-κB activation. | 2017 | Mol. Cancer | pmid:28178994 |
| Dou Q et al. | CRE and SRE mediate LPA-induced CCN1 transcription in mouse aortic smooth muscle cells. | 2017 | Can. J. Physiol. Pharmacol. | pmid:28157379 |
| Emoto S et al. | Analysis of glycero-lysophospholipids in gastric cancerous ascites. | 2017 | J. Lipid Res. | pmid:28143894 |
| Joncour A et al. | Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors. | 2017 | J. Med. Chem. | pmid:28731719 |
| Valdés-Rives SA and González-Arenas A | Autotaxin-Lysophosphatidic Acid: From Inflammation to Cancer Development. | 2017 | Mediators Inflamm. | pmid:29430083 |
| Takara K et al. | Lysophosphatidic Acid Receptor 4 Activation Augments Drug Delivery in Tumors by Tightening Endothelial Cell-Cell Contact. | 2017 | Cell Rep | pmid:28854359 |
| McDougall M et al. | Chronic vitamin E deficiency impairs cognitive function in adult zebrafish via dysregulation of brain lipids and energy metabolism. | 2017 | Free Radic. Biol. Med. | pmid:28790013 |
| Wang Y et al. | Synergistic Tailoring of Electrostatic and Hydrophobic Interactions for Rapid and Specific Recognition of Lysophosphatidic Acid, an Early-Stage Ovarian Cancer Biomarker. | 2017 | J. Am. Chem. Soc. | pmid:28782946 |
| Li N et al. | Lysophosphatidic acid enhances human umbilical cord mesenchymal stem cell viability without differentiation via LPA receptor mediating manner. | 2017 | Apoptosis | pmid:28766061 |
| Mirzoyan K et al. | Lysophosphatidic Acid Protects Against Endotoxin-Induced Acute Kidney Injury. | 2017 | Inflammation | pmid:28667502 |
| Bosetti M et al. | Injectable Graft Substitute Active on Bone Tissue Regeneration. | 2017 | Tissue Eng Part A | pmid:28530130 |
| Nsaibia MJ et al. | OxLDL-derived lysophosphatidic acid promotes the progression of aortic valve stenosis through a LPAR1-RhoA-NF-κB pathway. | 2017 | Cardiovasc. Res. | pmid:28472283 |
| Thorlakson HH et al. | Lysophosphatidic acid induces expression of genes in human oral keratinocytes involved in wound healing. | 2017 | Arch. Oral Biol. | pmid:28432900 |
| Sordelli MS et al. | Endogenous lysophosphatidic acid participates in vascularisation and decidualisation at the maternal-fetal interface in the rat. | 2017 | Reprod. Fertil. Dev. | pmid:28376314 |
| Zhang K et al. | Hypertrophy and Fibrosis of the Ligamentum Flavum in Lumbar Spinal Stenosis is Associated With Increased Expression of LPA and LPAR1. | 2017 | Clin Spine Surg | pmid:28323698 |
| Yanamandra M et al. | Development of highly sensitive cell-based AKT kinase ELISA for monitoring PI3K beta activity and compound efficacy. | 2017 | J Immunoassay Immunochem | pmid:29035165 |
| Sinderewicz E et al. | Expression of factors involved in apoptosis and cell survival is correlated with enzymes synthesizing lysophosphatidic acid and its receptors in granulosa cells originating from different types of bovine ovarian follicles. | 2017 | Reprod. Biol. Endocrinol. | pmid:28874163 |
| Taniguchi R et al. | Structural insights into ligand recognition by the lysophosphatidic acid receptor LPA. | 2017 | Nature | pmid:28792932 |
| Zheng H et al. | mTOR signaling promotes foam cell formation and inhibits foam cell egress through suppressing the SIRT1 signaling pathway. | 2017 | Mol Med Rep | pmid:28765952 |
| Michalczyk A et al. | Lysophosphatidic acid plasma concentrations in healthy subjects: circadian rhythm and associations with demographic, anthropometric and biochemical parameters. | 2017 | Lipids Health Dis | pmid:28732508 |
| Oh YS et al. | Dynamic relocalization of NHERF1 mediates chemotactic migration of ovarian cancer cells toward lysophosphatidic acid stimulation. | 2017 | Exp. Mol. Med. | pmid:28684865 |
| Lötsch J et al. | Machine-Learned Data Structures of Lipid Marker Serum Concentrations in Multiple Sclerosis Patients Differ from Those in Healthy Subjects. | 2017 | Int J Mol Sci | pmid:28590455 |
| Zhang JB et al. | Plasma Phospholipids are Associated with Mild Cognitive Impairment in Type 2 Diabetic Patients. | 2017 | Curr Alzheimer Res | pmid:27915992 |
| Chen L et al. | Lysophosphatidic acid directly induces macrophage-derived foam cell formation by blocking the expression of SRBI. | 2017 | Biochem. Biophys. Res. Commun. | pmid:28765047 |
| Tsukahara T et al. | Lysophosphatidic acid signaling regulates the KLF9-PPARγ axis in human induced pluripotent stem cell-derived neurons. | 2017 | Biochem. Biophys. Res. Commun. | pmid:28716732 |
| An D et al. | CD14 is a key mediator of both lysophosphatidic acid and lipopolysaccharide induction of foam cell formation. | 2017 | J. Biol. Chem. | pmid:28705936 |
| Lopane C et al. | Implications of the lysophosphatidic acid signaling axis in liver cancer. | 2017 | Biochim Biophys Acta Rev Cancer | pmid:28591560 |
| Ray R and Rai V | Lysophosphatidic acid converts monocytes into macrophages in both mice and humans. | 2017 | Blood | pmid:28069607 |
| Tsutsumi T et al. | Daily Intake of High-Fat Diet with Lysophosphatidic Acid-Rich Soybean Phospholipids Augments Colon Tumorigenesis in Kyoto Apc Delta Rats. | 2017 | Dig. Dis. Sci. | pmid:28050783 |
| Takahashi K et al. | Lysophosphatidic acid (LPA) signaling via LPA and LPA negatively regulates cell motile activities of colon cancer cells. | 2017 | Biochem. Biophys. Res. Commun. | pmid:27993681 |
| Sakai N et al. | Lysophosphatidic acid signaling through its receptor initiates profibrotic epithelial cell fibroblast communication mediated by epithelial cell derived connective tissue growth factor. | 2017 | Kidney Int. | pmid:27927603 |
| Kang TS et al. | A rhodium(III)-based inhibitor of autotaxin with antiproliferative activity. | 2017 | Biochim Biophys Acta Gen Subj | pmid:27888146 |
| Niss Arfelt K et al. | Signaling via G proteins mediates tumorigenic effects of GPR87. | 2017 | Cell. Signal. | pmid:27865873 |
| Sattikar A et al. | Endogenous lysophosphatidic acid (LPA ) receptor agonists demonstrate ligand bias between calcium and ERK signalling pathways in human lung fibroblasts. | 2017 | Br. J. Pharmacol. | pmid:27864940 |
| Scheiblich H and Bicker G | Regulation of Microglial Phagocytosis by RhoA/ROCK-Inhibiting Drugs. | 2017 | Cell. Mol. Neurobiol. | pmid:27178562 |
| Tafelmeier M et al. | Mildly oxidized HDL decrease agonist-induced platelet aggregation and release of pro-coagulant platelet extracellular vesicles. | 2017 | J. Steroid Biochem. Mol. Biol. | pmid:27163393 |
| Velasco M et al. | Lysophosphatidic acid receptors (LPARs): Potential targets for the treatment of neuropathic pain. | 2017 | Neuropharmacology | pmid:27059127 |
| Ren X et al. | LC-MS based metabolomics identification of novel biomarkers of tobacco smoke-induced chronic bronchitis. | 2016 | Biomed. Chromatogr. | pmid:26390017 |
| Tveteraas IH et al. | Lysophosphatidic acid induces both EGFR-dependent and EGFR-independent effects on DNA synthesis and migration in pancreatic and colorectal carcinoma cells. | 2016 | Tumour Biol. | pmid:26386720 |
| Boruszewska D et al. | Studies on lysophosphatidic acid action during in vitro preimplantation embryo development. | 2016 | Domest. Anim. Endocrinol. | pmid:26379100 |
| Sun K et al. | Curcumin inhibits LPA-induced invasion by attenuating RhoA/ROCK/MMPs pathway in MCF7 breast cancer cells. | 2016 | Clin. Exp. Med. | pmid:25596714 |
| Ragle LE et al. | Discovery and synthetic optimization of a novel scaffold for hydrophobic tunnel-targeted autotaxin inhibition. | 2016 | Bioorg. Med. Chem. | pmid:27544588 |
| Olianas MC et al. | LPA1 Mediates Antidepressant-Induced ERK1/2 Signaling and Protection from Oxidative Stress in Glial Cells. | 2016 | J. Pharmacol. Exp. Ther. | pmid:27605627 |
| Cheng J et al. | Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling. | 2016 | Neuron | pmid:27641493 |
| Pan HL et al. | Modulation of Nav1.8 by Lysophosphatidic Acid in the Induction of Bone Cancer Pain. | 2016 | Neurosci Bull | pmid:27631681 |
| Plastira I et al. | 1-Oleyl-lysophosphatidic acid (LPA) promotes polarization of BV-2 and primary murine microglia towards an M1-like phenotype. | 2016 | J Neuroinflammation | pmid:27565558 |
| Gibbs-Bar L et al. | Autotaxin-Lysophosphatidic Acid Axis Acts Downstream of Apoprotein B Lipoproteins in Endothelial Cells. | 2016 | Arterioscler. Thromb. Vasc. Biol. | pmid:27562917 |
| Amiar S et al. | Apicoplast-Localized Lysophosphatidic Acid Precursor Assembly Is Required for Bulk Phospholipid Synthesis in Toxoplasma gondii and Relies on an Algal/Plant-Like Glycerol 3-Phosphate Acyltransferase. | 2016 | PLoS Pathog. | pmid:27490259 |
| Hopkins MM et al. | Positive and Negative Cross-Talk between Lysophosphatidic Acid Receptor 1, Free Fatty Acid Receptor 4, and Epidermal Growth Factor Receptor in Human Prostate Cancer Cells. | 2016 | J. Pharmacol. Exp. Ther. | pmid:27474750 |
| Liu X et al. | PRG-1 Regulates Synaptic Plasticity via Intracellular PP2A/β1-Integrin Signaling. | 2016 | Dev. Cell | pmid:27453502 |
| Fleming JK et al. | A novel approach for measuring sphingosine-1-phosphate and lysophosphatidic acid binding to carrier proteins using monoclonal antibodies and the Kinetic Exclusion Assay. | 2016 | J. Lipid Res. | pmid:27444045 |
| Tong S et al. | Structural Insight into Substrate Selection and Catalysis of Lipid Phosphate Phosphatase PgpB in the Cell Membrane. | 2016 | J. Biol. Chem. | pmid:27405756 |
| Sweat RS et al. | Lysophosphatidic acid does not cause blood/lymphatic vessel plasticity in the rat mesentery culture model. | 2016 | Physiol Rep | pmid:27401461 |
| Del Bas JM et al. | Impairment of lysophospholipid metabolism in obesity: altered plasma profile and desensitization to the modulatory properties of n-3 polyunsaturated fatty acids in a randomized controlled trial. | 2016 | Am. J. Clin. Nutr. | pmid:27305954 |
| Wesseling MC et al. | Measurements of Intracellular Ca2+ Content and Phosphatidylserine Exposure in Human Red Blood Cells: Methodological Issues. | 2016 | Cell. Physiol. Biochem. | pmid:27287398 |
| Hövelmann F et al. | Optotaxis: Caged Lysophosphatidic Acid Enables Optical Control of a Chemotactic Gradient. | 2016 | Cell Chem Biol | pmid:27161483 |
| Ferru-Clément R et al. | Targeting surface voids to counter membrane disorders in lipointoxication-related diseases. | 2016 | J. Cell. Sci. | pmid:27142833 |
| Yoshida M et al. | Transgenic Expression of Human Lysophosphatidic Acid Receptor LPA2 in Mouse Intestinal Epithelial Cells Induces Intestinal Dysplasia. | 2016 | PLoS ONE | pmid:27124742 |
| Ackerman SJ et al. | Polyunsaturated lysophosphatidic acid as a potential asthma biomarker. | 2016 | Biomark Med | pmid:26808693 |
| Funke M et al. | Lysophosphatidic Acid Signaling through the Lysophosphatidic Acid-1 Receptor Is Required for Alveolarization. | 2016 | Am. J. Respir. Cell Mol. Biol. | pmid:27082727 |
| Riaz A et al. | G-Protein-Coupled Lysophosphatidic Acid Receptors and Their Regulation of AKT Signaling. | 2016 | Int J Mol Sci | pmid:26861299 |
| Hashimoto S et al. | Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer. | 2016 | Nat Commun | pmid:26854204 |
| Takeda A et al. | Fibroblastic reticular cell-derived lysophosphatidic acid regulates confined intranodal T-cell motility. | 2016 | Elife | pmid:26830463 |
| Seo EJ et al. | Autotaxin Regulates Maintenance of Ovarian Cancer Stem Cells through Lysophosphatidic Acid-Mediated Autocrine Mechanism. | 2016 | Stem Cells | pmid:26800320 |
| Du C et al. | KLF5 promotes cell migration by up-regulating FYN in bladder cancer cells. | 2016 | FEBS Lett. | pmid:26786295 |
| Wang Z | Transactivation of Epidermal Growth Factor Receptor by G Protein-Coupled Receptors: Recent Progress, Challenges and Future Research. | 2016 | Int J Mol Sci | pmid:26771606 |
| Park R et al. | Yap is required for ependymal integrity and is suppressed in LPA-induced hydrocephalus. | 2016 | Nat Commun | pmid:26754915 |
| Kedziora KM et al. | Rapid Remodeling of Invadosomes by Gi-coupled Receptors: DISSECTING THE ROLE OF Rho GTPases. | 2016 | J. Biol. Chem. | pmid:26740622 |
| Cai T et al. | Characterization and relative quantification of phospholipids based on methylation and stable isotopic labeling. | 2016 | J. Lipid Res. | pmid:26733148 |
| Zuckerman V et al. | Expression and function of lysophosphatidic acid receptors (LPARs) 1 and 3 in human hepatic cancer progenitor cells. | 2016 | Oncotarget | pmid:26701886 |
| Vogt J et al. | Molecular cause and functional impact of altered synaptic lipid signaling due to a prg-1 gene SNP. | 2016 | EMBO Mol Med | pmid:26671989 |
| Nan L et al. | Cross-talk between lysophosphatidic acid receptor 1 and tropomyosin receptor kinase A promotes lung epithelial cell migration. | 2016 | Biochim. Biophys. Acta | pmid:26597701 |
| Kritikou E et al. | Inhibition of lysophosphatidic acid receptors 1 and 3 attenuates atherosclerosis development in LDL-receptor deficient mice. | 2016 | Sci Rep | pmid:27883026 |
| Wunsch E et al. | Serum Autotaxin is a Marker of the Severity of Liver Injury and Overall Survival in Patients with Cholestatic Liver Diseases. | 2016 | Sci Rep | pmid:27506882 |
| Pagliuso A et al. | Golgi membrane fission requires the CtBP1-S/BARS-induced activation of lysophosphatidic acid acyltransferase δ. | 2016 | Nat Commun | pmid:27401954 |
| Ha JH et al. | Aberrant expression of JNK-associated leucine-zipper protein, JLP, promotes accelerated growth of ovarian cancer. | 2016 | Oncotarget | pmid:27655714 |
| Chen Z et al. | Simulated microgravity inhibits osteogenic differentiation of mesenchymal stem cells via depolymerizing F-actin to impede TAZ nuclear translocation. | 2016 | Sci Rep | pmid:27444891 |
| Hao F et al. | Lysophosphatidic acid-induced vascular neointimal formation in mouse carotid arteries is mediated by the matricellular protein CCN1/Cyr61. | 2016 | Am. J. Physiol., Cell Physiol. | pmid:27760754 |
| Touat-Hamici Z et al. | Role of lipid phosphate phosphatase 3 in human aortic endothelial cell function. | 2016 | Cardiovasc. Res. | pmid:27694435 |
| Mirzoyan K et al. | Increased urinary lysophosphatidic acid in mouse with subtotal nephrectomy: potential involvement in chronic kidney disease. | 2016 | J. Physiol. Biochem. | pmid:27637780 |
| Yang B et al. | The effect of lysophosphatidic acid on Toll-like receptor 4 expression and the nuclear factor-κB signaling pathway in THP-1 cells. | 2016 | Mol. Cell. Biochem. | pmid:27619660 |
| Mittal A | Cholestatic Itch Management. | 2016 | Curr. Probl. Dermatol. | pmid:27578083 |
| Kostadinova L et al. | During Hepatitis C Virus (HCV) Infection and HCV-HIV Coinfection, an Elevated Plasma Level of Autotaxin Is Associated With Lysophosphatidic Acid and Markers of Immune Activation That Normalize During Interferon-Free HCV Therapy. | 2016 | J. Infect. Dis. | pmid:27540113 |
| Shimomura Y | Journey toward unraveling the molecular basis of hereditary hair disorders. | 2016 | J. Dermatol. Sci. | pmid:27523806 |
| Might KR et al. | The effect of lysophosphatidic acid using a hydrogel or collagen sponge carrier on bone healing in dogs. | 2016 | Vet Comp Orthop Traumatol | pmid:27432270 |
| Castelino FV et al. | An Autotaxin/Lysophosphatidic Acid/Interleukin-6 Amplification Loop Drives Scleroderma Fibrosis. | 2016 | pmid:27390295 | |
| Sinderewicz E et al. | Lysophosphatidic Acid Synthesis and its Receptors' Expression in the Bovine Oviduct During the Oestrous Cycle. | 2016 | Reprod. Domest. Anim. | pmid:27335048 |
| Hausmann J et al. | Structural snapshots of the catalytic cycle of the phosphodiesterase Autotaxin. | 2016 | J. Struct. Biol. | pmid:27268273 |
| Tsutsumi T et al. | Reduced rat plasma lysophosphatidylglycerol or lysophosphatidic acid level as a biomarker of aristolochic acid-induced renal and adipose dysfunctions. | 2016 | Life Sci. | pmid:27267499 |
| Lindholm PF and Hwang YS | LPA Increases Tumor Growth and Bone Destruction Through Enhancement of Osteoclastogenic Cytokines. | 2016 | Anticancer Res. | pmid:26722028 |
| Ayre WN et al. | Fluorophosphonate-functionalised titanium via a pre-adsorbed alkane phosphonic acid: a novel dual action surface finish for bone regenerative applications. | 2016 | J Mater Sci Mater Med | pmid:26704553 |
| Hwang YS et al. | Lysophosphatidic acid activates the RhoA and NF-κB through Akt/IκBα signaling and promotes prostate cancer invasion and progression by enhancing functional invadopodia formation. | 2016 | Tumour Biol. | pmid:26662305 |
| Aasrum M et al. | PI3K is required for both basal and LPA-induced DNA synthesis in oral carcinoma cells. | 2016 | J. Oral Pathol. Med. | pmid:26602326 |