stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Abortion, Spontaneous D000022 12 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Adenoma D000236 40 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amnesia D000647 12 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Olfaction Disorders D000857 17 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Dawes J et al. Application of external lubrication during the roller compaction of adhesive pharmaceutical formulations. 2013 Pharm Dev Technol pmid:22813432
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Intorre F et al. Fatty acid content of serum lipid fractions and blood lipids in normolipidaemic volunteers fed two types of cheese having different fat compositions: a pilot study. 2013 Int J Food Sci Nutr pmid:22849318
Emken E Human studies using isotope labeled fatty acids: answered and unanswered questions. 2013 J Oleo Sci pmid:23648399
Dangarembizi R et al. Aloe ferox seed: a potential source of oil for cosmetic and pharmaceutical use. 2013 Nat Prod Commun pmid:23678824
Maia M et al. A novel, direct, reagent-free method for the detection of beeswax adulteration by single-reflection attenuated total reflectance mid-infrared spectroscopy. 2013 Talanta pmid:23598195
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Salehi M et al. Debinding mechanisms in thermoplastic processing of a Ba(0.5)Sr(0.5)Co(0.8)Fe(0.2)O(3-δ)- stearic acid-polystyrene mixture. 2013 ChemSusChem pmid:23281298
He M et al. Controllable stearic acid crystal induced high hydrophobicity on cellulose film surface. 2013 ACS Appl Mater Interfaces pmid:23289586
Wan Q et al. Self-assembled magnetic theranostic nanoparticles for highly sensitive MRI of minicircle DNA delivery. 2013 Nanoscale pmid:23224057
Li C et al. Enhanced performance and interfacial investigation of mineral-based composite phase change materials for thermal energy storage. 2013 Sci Rep pmid:23712069
Lakio S et al. Challenges in detecting magnesium stearate distribution in tablets. 2013 AAPS PharmSciTech pmid:23378252
Järvinen MA et al. Continuous direct tablet compression: effects of impeller rotation rate, total feed rate and drug content on the tablet properties and drug release. 2013 Drug Dev Ind Pharm pmid:23163644
Schrank S et al. Microstructure of calcium stearate matrix pellets: a function of the drying process. 2013 J Pharm Sci pmid:23983150
Yang C et al. Production of aviation fuel via catalytic hydrothermal decarboxylation of fatty acids in microalgae oil. 2013 Bioresour. Technol. pmid:23973977
Zhang W et al. Stearylated antimicrobial peptide melittin and its retro isomer for efficient gene transfection. 2013 Bioconjug. Chem. pmid:24107137
Yan J et al. Effect of proteins with different isoelectric points on the gene transfection efficiency mediated by stearic acid grafted chitosan oligosaccharide micelles. 2013 Mol. Pharm. pmid:23679858
Kwan HY et al. The anticancer effect of oridonin is mediated by fatty acid synthase suppression in human colorectal cancer cells. 2013 J. Gastroenterol. pmid:22722903
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Hentzschel CM et al. Comparison of traditional and novel tableting excipients: physical and compaction properties. 2012 Nov-Dec Pharm Dev Technol pmid:21740091
Khan FN and Dehghan MH Enhanced Bioavailability and Dissolution of Atorvastatin Calcium from Floating Microcapsules using Minimum Additives. 2012 Jan-Mar Sci Pharm pmid:22396916
Pujeri SS et al. Stress degradation studies on varenicline tartrate and development of a validated stability-indicating HPLC method. 2012 Jan-Mar Sci Pharm pmid:22396908
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Vijay J et al. Formulation and Evaluation of Cephalexin Extended-release Matrix Tablets Using Hydroxy Propyl Methyl Cellulose as Rate-controlling Polymer. 2012 J Young Pharm pmid:22523453
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Kwon Y et al. Arabidopsis serine decarboxylase mutants implicate the roles of ethanolamine in plant growth and development. 2012 Int J Mol Sci pmid:22489147
Morales A et al. Quantitative analysis of hydroperoxy-, keto- and hydroxy-dienes in refined vegetable oils. 2012 J Chromatogr A pmid:22321954
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Ahn BJ et al. Solvent-free acid-catalyzed ring-opening of epoxidized oleochemicals using stearates/stearic acid, and its applications. 2012 J. Agric. Food Chem. pmid:22304525
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Zhen Z and Xie J Development of manganese-based nanoparticles as contrast probes for magnetic resonance imaging. 2012 Theranostics pmid:22272218
Xie YT et al. Brain-targeting study of stearic acid-grafted chitosan micelle drug-delivery system. 2012 Int J Nanomedicine pmid:22802685
El Semary NA The antimicrobial profile of extracts of a Phormidium-like cyanobacterium changes with phosphate levels. 2012 World J. Microbiol. Biotechnol. pmid:22806854
Busignies V et al. Prediction of the compressibility of complex mixtures of pharmaceutical powders. 2012 Int J Pharm pmid:22759643
Jubie S et al. Synthesis, antidepressant and antimicrobial activities of some novel stearic acid analogues. 2012 Eur J Med Chem pmid:22770606
Krogager TP et al. Identification of a potential biomarker panel for the intake of the common dietary trans fat elaidic acid (trans∆9-C18:1). 2012 J Proteomics pmid:22483997
Chapple IL et al. Adjunctive daily supplementation with encapsulated fruit, vegetable and berry juice powder concentrates and clinical periodontal outcomes: a double-blind RCT. 2012 J. Clin. Periodontol. pmid:22093005
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Liu J et al. Stearoyl-acyl carrier protein desaturase gene from the oleaginous microalga Chlorella zofingiensis: cloning, characterization and transcriptional analysis. 2012 Planta pmid:22855030
Carol D et al. Synergistic effect of calcium stearate and photo treatment on the rate of biodegradation of low density polyethylene spent saline vials. 2012 Indian J. Exp. Biol. pmid:22822530
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Hu FQ et al. pH triggered doxorubicin delivery of PEGylated glycolipid conjugate micelles for tumor targeting therapy. 2012 Mol. Pharm. pmid:22827551
Sellami M et al. Enzymatic transesterification of palm stearin and olein blends to produce zero-trans margarine fat. 2012 BMC Biotechnol. pmid:22889174
Schreiber R et al. Retinyl ester hydrolases and their roles in vitamin A homeostasis. 2012 Biochim. Biophys. Acta pmid:21586336
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Niu J et al. Octreotide-modified and pH-triggering polymeric micelles loaded with doxorubicin for tumor targeting delivery. 2012 Eur J Pharm Sci pmid:22119655
Jung HA and Augsburger LL Application of a novel automatic disintegration apparatus for the development and evaluation of a direct compression rapidly disintegrating tablet. 2012 Drug Dev Ind Pharm pmid:22091970
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