stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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pmid: | ||||
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Kelly FD et al. | Stearic acid-rich diets do not increase thrombotic risk factors in healthy males. | 1999 | Lipids | pmid:10419148 |
Muszbek L et al. | The pool of fatty acids covalently bound to platelet proteins by thioester linkages can be altered by exogenously supplied fatty acids. | 1999 | Lipids | pmid:10419194 |
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Warnotte C et al. | Unbound rather than total concentration and saturation rather than unsaturation determine the potency of fatty acids on insulin secretion. | 1999 | Mol. Cell. Endocrinol. | pmid:10459862 |
Eliasen H et al. | Growth mechanisms in melt agglomeration with a low viscosity binder. | 1999 | Int J Pharm | pmid:10486433 |
Summers LK et al. | Use of structured triacylglycerols containing predominantly stearic and oleic acids to probe early events in metabolic processing of dietary fat. | 1999 | J. Lipid Res. | pmid:10508209 |
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Chajès V et al. | Fatty-acid composition in serum phospholipids and risk of breast cancer: an incident case-control study in Sweden. | 1999 | Int. J. Cancer | pmid:10521790 |
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Connor WE | Harbingers of coronary heart disease: dietary saturated fatty acids and cholesterol. Is chocolate benign because of its stearic acid content? | 1999 | Am. J. Clin. Nutr. | pmid:10584037 |
Liu CY et al. | Synthesis and analytical properties of a novel columnar metallomesogenic polymer. | 1999 | J Chromatogr A | pmid:10588341 |
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Wright LC et al. | The origin of 1H NMR-visible triacylglycerol in human neutrophils. Highfatty acid environments result in preferential sequestration of palmitic acid into plasma membrane triacylglycerol. | 2000 | Eur. J. Biochem. | pmid:10601852 |
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González MS and Brenner RR | Fatty acid delta9-desaturation in the Triatoma infestans fat body: response to food and trehalose administrations. | 1999 | Lipids | pmid:10606043 |
Weston WL and Morelli JG | Steroid rosacea in prepubertal children. | 2000 | Arch Pediatr Adolesc Med | pmid:10632252 |
Rukkwamsuk T et al. | Interrelation of fatty acid composition in adipose tissue, serum, and liver of dairy cows during the development of fatty liver postpartum. | 2000 | J. Dairy Sci. | pmid:10659963 |
Alonso A et al. | Lipid chain dynamics in stratum corneum studied by spin label electron paramagnetic resonance. | 2000 | Chem. Phys. Lipids | pmid:10669304 |
Otz M and Thoma H | Effects of the metal type and the roughness of the die wall on the expended work for tablet ejection. | 2000 | Pharm Dev Technol | pmid:10669914 |