stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Thiel WJ and Sberna FJ | Fluidized bed film coating of an interactive powder mixture to produce microencapsulated 2-5 microns particles. | 1986 | J. Pharm. Pharmacol. | pmid:2871149 |
Hattori T et al. | Attenuation by pentobarbital of free fatty acid and diacylglycerol liberation during global ischaemia in rat brain. | 1986 | Neurol. Res. | pmid:2871507 |
Catalá A | Stearic acid desaturation in rat liver microsomes: stimulation by fatty acid binding protein. | 1986 | Acta Physiol Pharmacol Latinoam | pmid:2876583 |
Gotoh K et al. | Effects of unsaturated fatty acids on the peroxisomal enzyme activities of Tetrahymena pyriformis. | 1986 | J. Biochem. | pmid:2880840 |
Crosby T et al. | Identification of ecdysone 22-long-chain fatty acyl esters in newly laid eggs of the cattle tick Boophilus microplus. | 1986 | Biochem. J. | pmid:3030275 |
Reddy TS et al. | Fatty acid composition and arachidonic acid metabolism in vitreous lipids from canine and human eyes. | 1986 | Curr. Eye Res. | pmid:3089690 |
Dudley DT and Spector AA | Inositol phospholipid arachidonic acid metabolism in GH3 pituitary cells. | 1986 | Biochem. J. | pmid:3098231 |
Carter-Dawson L et al. | Rhodopsin, 11-cis vitamin A, and interstitial retinol-binding protein (IRBP) during retinal development in normal and rd mutant mice. | 1986 | Dev. Biol. | pmid:3732615 |
Chowhan ZT and Chi LH | Drug-excipient interactions resulting from powder mixing. III: Solid state properties and their effect on drug dissolution. | 1986 | J Pharm Sci | pmid:3735096 |
Chowhan ZT and Chi LH | Drug-excipient interactions resulting from powder mixing. IV: Role of lubricants and their effect on in vitro dissolution. | 1986 | J Pharm Sci | pmid:3735097 |
Fujii T et al. | Effect of exogenous lipids incorporated into the membrane of human erythrocytes on its glucose transport activity. | 1986 | Biochem. Int. | pmid:3741447 |
Chester DW et al. | The influence of saturated fatty acid modulation of bilayer physical state on cellular and membrane structure and function. | 1986 | Biochim. Biophys. Acta | pmid:3741857 |
Tsao FH | Selective use of palmitic acid over stearic acid for synthesis of phosphatidylcholine and phosphatidylglycerol in lung. | 1986 | Lipids | pmid:3796238 |
Ito Y et al. | Fatty acid synthetase as a thermoreceptor in Candida utilis. | 1986 | J. Biochem. | pmid:3745143 |
Muralidharan FN and Muralidharan VB | Phytanoyl-CoA ligase activity in rat liver. | 1986 | Biochem. Int. | pmid:3753503 |
Ball MD et al. | Acyl coenzyme A:retinol acyltransferase activity and the vitamin A content of polar bear (Ursus maritimus) liver. | 1986 | Comp. Biochem. Physiol., B | pmid:3757481 |
van den Reek MM et al. | Use of published analyses of food items to determine dietary trans octadecenoic acid. | 1986 | J Am Diet Assoc | pmid:3760430 |
Sugimoto Y et al. | A 2H NMR study on alteration of the membrane organization of mouse B16 melanoma cells treated with 12-O-tetradecanoylphorbol-13-acetate. | 1986 | J. Biochem. | pmid:3818567 |
Thompson W and Belina H | Rapid accumulation of diacyl lipid in rat liver microsomes by selective acylation of 2-acyl-sn-glycero-3-phosphorylserine. | 1986 | Biochim. Biophys. Acta | pmid:3707975 |
Heape AM et al. | Technique for injection into the sciatic nerve of the mouse for quantitative in vivo metabolic studies. | 1986 | Anal. Biochem. | pmid:3717558 |
Pajor L et al. | Microsomal desaturation of stearic acid in relation to lymphocyte activation. | 1986 | Arch. Biochem. Biophys. | pmid:3485399 |
Ras GJ and Anderson R | An in-vitro study of oral therapeutic doses of co-trimoxazole and erythromycin stearate on abnormal polymorphonuclear leucocyte migration. | 1986 | J. Antimicrob. Chemother. | pmid:3486178 |
Muñoz-Espin T et al. | Erythromycin versus tetracycline for treatment of Mediterranean spotted fever. | 1986 | Arch. Dis. Child. | pmid:3535687 |
Sakaguchi M et al. | Effects of dietary saturated and unsaturated fatty acids on fecal bile acids and colon carcinogenesis induced by azoxymethane in rats. | 1986 | Cancer Res. | pmid:3940210 |
Bankson DD et al. | Determination of retinyl esters and retinol in serum or plasma by normal-phase liquid chromatography: method and applications. | 1986 | Clin. Chem. | pmid:3940733 |
Yamamoto O | Radiation-induced crosslinks between carboxylic acids and compounds of biological interest. | 1986 | Radiat. Res. | pmid:3952268 |
Villa P et al. | Effects of a new fluorinated macrolide (P-0501A) and other erythromycins on drug metabolizing enzymes in rat liver. | 1986 | J. Antibiot. | pmid:3084433 |
Okabe H et al. | Effects of anti-convulsants on fatty acid metabolism in human serum. | 1986 | Tohoku J. Exp. Med. | pmid:3705068 |
Siegel I et al. | Inhibition of sperm motility and agglutination of sperm cells by free fatty acids in whole semen. | 1986 | Fertil. Steril. | pmid:2868925 |
Johansson ME and Nicklasson M | Investigation of the film formation of magnesium stearate by applying a flow-through dissolution technique. | 1986 | J. Pharm. Pharmacol. | pmid:2869127 |
Tabachnick M and Korcek L | Effect of long-chain fatty acids on the binding of thyroxine and triiodothyronine to human thyroxine-binding globulin. | 1986 | Biochim. Biophys. Acta | pmid:2869786 |
Alcalay J et al. | Asymptomatic liver injury due to erythromycin stearate. | 1986 Jul-Aug | Drug Intell Clin Pharm | pmid:3743417 |
Goto S et al. | Eudragit RS and RL (acrylic resins) microcapsules as pH insensitive and sustained release preparations of ketoprofen. | 1986 Oct-Dec | J Microencapsul | pmid:3508190 |
Goto S et al. | Eudragit E, L and S (acrylic resins) microcapsules as pH sensitive release preparations of ketoprofen. | 1986 Oct-Dec | J Microencapsul | pmid:3508191 |
Adebayo GI et al. | Time-dependent inhibition of theophylline elimination by erythromycin stearate. | 1986 Sep-Oct | Biopharm Drug Dispos | pmid:3779037 |
Bergquist SO et al. | Erythromycin in the treatment of pertussis: a study of bacteriologic and clinical effects. | 1987 | Pediatr. Infect. Dis. J. | pmid:2885802 |
Zara GP et al. | Erythromycin and gastrointestinal motility. | 1987 | Lancet | pmid:2889954 |
Roughan PG et al. | Metabolism of exogenous long-chain fatty acids by spinach leaves. | 1987 | Arch. Biochem. Biophys. | pmid:3426240 |
Habib NA et al. | Stearic acid and carcinogenesis. | 1987 | Br. J. Cancer | pmid:3689663 |
Kaya K and Nohara K | Effect of di-n-octyl phthalate on fatty acid composition of phosphatidylcholine in Tetrahymena. | 1987 | Chem. Biol. Interact. | pmid:3690725 |
Berlin E et al. | Influence of saturated and unsaturated fats on platelet fatty acids in cholesterol-fed rabbits. | 1987 | Atherosclerosis | pmid:3827974 |
Nadai M et al. | [Correlation between in vitro dissolution characteristics of macrolide antibiotic tablets and bioavailability in man]. | 1987 | Yakugaku Zasshi | pmid:3437396 |
Hasin Y et al. | Dietary lipid intake and myocardial electrophysiology. | 1987 | Isr. J. Med. Sci. | pmid:3440741 |
Cutler RR et al. | The effect of polyoxyethylene stearate (POES) on the growth of mycobacteria in radiometric 7H12 Middlebrook TB medium. | 1987 | Tubercle | pmid:3448797 |
Matsui MS and Jeffrey AM | Fatty acid modification of C3H 10T 1/2 fibroblast cells: changes in benzo(a)pyrene metabolism and phorbol ester binding. | 1987 | Cancer Res. | pmid:3471326 |
Habib NA et al. | Desaturation-producing factor present in the tissue, blood, and urine of cancer patients. | 1987 | Cancer Detect. Prev. | pmid:3568009 |
Wang ST et al. | A comparison of fatty acid composition of cholesteryl esters in subjects at various concentrations of serum lipid. | 1987 | Clin. Biochem. | pmid:3568345 |
PospÃsilová B and Kubes J | [Stability of erythromycin stearate in coated tablets during the action of gastric juice in vitro]. | 1987 | Cesk Farm | pmid:3581192 |
Hattori T et al. | Membrane phospholipid composition and membrane fluidity of human brain tumour: a spin label study. | 1987 | Neurol. Res. | pmid:2883605 |
Søreide O et al. | Inadequacy of oleic acid in erythrocytes as a marker of malignancies. | 1987 | Br Med J (Clin Res Ed) | pmid:3103770 |