stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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Park JH et al. | Development of DH-I-180-3 loaded lipid nanoparticle for photodynamic therapy. | 2015 | Int J Pharm | pmid:26149935 |
de Paiva EJ et al. | Influence of two different alcohols in the esterification of fatty acids over layered zinc stearate/palmitate. | 2015 | Bioresour. Technol. | pmid:26143001 |
Ricci M et al. | Growth and Dissolution of Calcite in the Presence of Adsorbed Stearic Acid. | 2015 | Langmuir | pmid:26087312 |
Yang Y et al. | Ligand-directed stearic acid grafted chitosan micelles to increase therapeutic efficacy in hepatic cancer. | 2015 | Mol. Pharm. | pmid:25495890 |
Yi HX et al. | Effect of anionic PEGylated polypeptide on gene transfection mediated by glycolipid conjugate micelles. | 2015 | Mol. Pharm. | pmid:25490413 |
Momoh MA et al. | Influence of magnesium stearate on the physicochemical and pharmacodynamic characteristics of insulin-loaded Eudragit entrapped mucoadhesive microspheres. | 2015 | Drug Deliv | pmid:24670092 |
Doignon F et al. | Requirement of Phosphoinositides Containing Stearic Acid To Control Cell Polarity. | 2015 | Mol. Cell. Biol. | pmid:26711260 |
Veselỳ M et al. | Photocatalytic and Antimicrobial Activity of Printed Hybrid Titania/Silica Layers. | 2015 | J Nanosci Nanotechnol | pmid:26716211 |
Li Y et al. | Effects of sustained-release composite on the oxygen levels and sediment phosphorus fractions of an urban river in Shanghai. | 2014 Sep-Oct | Environ Technol | pmid:25145170 |
Mu L et al. | Erythrocyte saturated fatty acids and systemic inflammation in adults. | 2014 Nov-Dec | Nutrition | pmid:25280420 |