stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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MuselÃk J et al. | Influence of process parameters on content uniformity of a low dose active pharmaceutical ingredient in a tablet formulation according to GMP. | 2014 | Acta Pharm | pmid:25296681 |
Rico JE et al. | Compared with stearic acid, palmitic acid increased the yield of milk fat and improved feed efficiency across production level of cows. | 2014 | J. Dairy Sci. | pmid:24342689 |
Petridis L et al. | Spatial arrangement of organic compounds on a model mineral surface: implications for soil organic matter stabilization. | 2014 | Environ. Sci. Technol. | pmid:24328330 |
Maghsoodi M | Floating-pulsatile release multiparticulate system for chronopharmacotherapy: effect of some hydrophobic additives on the buoyancy and release behavior of particles. | 2014 | Drug Res (Stuttg) | pmid:23950100 |
Liau CP et al. | Preparation and characterization of polyhydroxybutyrate/polycaprolactone nanocomposites. | 2014 | ScientificWorldJournal | pmid:24600329 |
Woo JO et al. | Development of a controlled release of salicylic acid loaded stearic acid-oleic acid nanoparticles in cream for topical delivery. | 2014 | ScientificWorldJournal | pmid:24578624 |
Yee JK et al. | High oleic/stearic fatty-acid desaturation index in cord plasma from infants of mothers with gestational diabetes. | 2014 | J Perinatol | pmid:24577432 |
Sassa T et al. | Lorenzo's oil inhibits ELOVL1 and lowers the level of sphingomyelin with a saturated very long-chain fatty acid. | 2014 | J. Lipid Res. | pmid:24489110 |
Dou J et al. | Preparation and evaluation in vitro and in vivo of docetaxel loaded mixed micelles for oral administration. | 2014 | Colloids Surf B Biointerfaces | pmid:24157590 |
Meulenaar J et al. | Development of an extended-release formulation of capecitabine making use of in vitro-in vivo correlation modelling. | 2014 | J Pharm Sci | pmid:24311366 |