stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
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What functions are associated with stearic acid?
Related references are published most in these journals:
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What lipids are associated with stearic acid?
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What genes are associated with stearic acid?
Related references are published most in these journals:
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Di Vaio C et al. | Influence of some environmental factors on drupe maturation and olive oil composition. | 2013 | J. Sci. Food Agric. | pmid:22936522 |
| Ruddle P et al. | Effect of a novel mutation in a Δ9-stearoyl-ACP-desaturase on soybean seed oil composition. | 2013 | Theor. Appl. Genet. | pmid:22961205 |
| Dawes J et al. | Application of external lubrication during the roller compaction of adhesive pharmaceutical formulations. | 2013 | Pharm Dev Technol | pmid:22813432 |
| Horio T et al. | Measurement of flowability of lubricated powders by the vibrating tube method. | 2013 | Drug Dev Ind Pharm | pmid:22781029 |
| Stanisz B et al. | Effect of pharmaceutical excipients on the stability of angiotensin-converting enzyme inhibitors in their solid dosage formulations. | 2013 | Drug Dev Ind Pharm | pmid:22348774 |
| Mazel V et al. | The surface layer of pharmaceutical compacts: the role of the punch surface and its impact on the mechanical properties of the compacts. | 2013 | Int J Pharm | pmid:22902389 |
| Intorre F et al. | Fatty acid content of serum lipid fractions and blood lipids in normolipidaemic volunteers fed two types of cheese having different fat compositions: a pilot study. | 2013 | Int J Food Sci Nutr | pmid:22849318 |
| Němcová-Fürstová V et al. | Caspase-2 and JNK activated by saturated fatty acids are not involved in apoptosis induction but modulate ER stress in human pancreatic β-cells. | 2013 | Cell. Physiol. Biochem. | pmid:23466956 |
| Franc A et al. | [Content uniformity of warfarin-containing mixtures and tablets]. | 2013 | Ceska Slov Farm | pmid:24047147 |
| Li L et al. | Drug release characteristics from chitosan-alginate matrix tablets based on the theory of self-assembled film. | 2013 | Int J Pharm | pmid:23624081 |
| MužÃková J and Sináglová P | A study of a new co-processed dry binder based on spray-dried lactose and microcrystalline cellulose. | 2013 | Ceska Slov Farm | pmid:23961814 |
| Neutsch L et al. | UPEC biomimickry at the urothelial barrier: lectin-functionalized PLGA microparticles for improved intravesical chemotherapy. | 2013 | Int J Pharm | pmid:23628404 |
| Emken E | Human studies using isotope labeled fatty acids: answered and unanswered questions. | 2013 | J Oleo Sci | pmid:23648399 |
| Dangarembizi R et al. | Aloe ferox seed: a potential source of oil for cosmetic and pharmaceutical use. | 2013 | Nat Prod Commun | pmid:23678824 |
| Maia M et al. | A novel, direct, reagent-free method for the detection of beeswax adulteration by single-reflection attenuated total reflectance mid-infrared spectroscopy. | 2013 | Talanta | pmid:23598195 |
| Li CC et al. | [In situ rat intestine absorption of paclitaxel-loaded solid lipid nanoparticles modified with cell-penetrating peptides]. | 2013 | Yao Xue Xue Bao | pmid:23600154 |
| Salehi M et al. | Debinding mechanisms in thermoplastic processing of a Ba(0.5)Sr(0.5)Co(0.8)Fe(0.2)O(3-δ)- stearic acid-polystyrene mixture. | 2013 | ChemSusChem | pmid:23281298 |
| He M et al. | Controllable stearic acid crystal induced high hydrophobicity on cellulose film surface. | 2013 | ACS Appl Mater Interfaces | pmid:23289586 |
| Wan Q et al. | Self-assembled magnetic theranostic nanoparticles for highly sensitive MRI of minicircle DNA delivery. | 2013 | Nanoscale | pmid:23224057 |
| Dhasaiyan P et al. | Influence of the sophorolipid molecular geometry on their self-assembled structures. | 2013 | Chem Asian J | pmid:23208802 |
| Baek JS and Cho CW | 2-Hydroxypropyl-β-cyclodextrin-modified SLN of paclitaxel for overcoming p-glycoprotein function in multidrug-resistant breast cancer cells. | 2013 | J. Pharm. Pharmacol. | pmid:23215690 |
| Hu P et al. | Genotoxicity evaluation of stearic acid grafted chitosan oligosaccharide nanomicelles. | 2013 | Mutat. Res. | pmid:23274307 |
| Wu X et al. | Alkanethiol-functionalized terahertz metamaterial as label-free, highly-sensitive and specific biosensor. | 2013 | Biosens Bioelectron | pmid:23261700 |
| Zhou X et al. | The effect of saturated fatty acids on methanogenesis and cell viability of Methanobrevibacter ruminantium. | 2013 | Archaea | pmid:23710130 |
| Gotoh K et al. | Evaluation of removal of model particulate and oily soils from poly(ethylene terephthalate) films by microscopic image analysis. | 2013 | J Oleo Sci | pmid:23391530 |
| Silberstein T et al. | Saturated fatty acid composition of human milk in Israel: a comparison between Jewish and Bedouin women. | 2013 | Isr. Med. Assoc. J. | pmid:23781748 |
| Ogata F et al. | Study on analysis of waste edible oil with deterioration and removal of acid value, carbonyl value, and free fatty acid by a food additive (calcium silicate). | 2013 | J Oleo Sci | pmid:23391535 |
| Ishida Y et al. | Fatty acid solubilizer from the oral disk of the blowfly. | 2013 | PLoS ONE | pmid:23326317 |
| Delbecq F et al. | N-stearoyl amino acid derivatives: potent biomimetic hydro/organogelators as templates for preparation of gold nanoparticles. | 2013 | J Colloid Interface Sci | pmid:23089597 |
| Han SH et al. | Bioinspired self-assembled peptide nanofibers with thermostable multivalent α-helices. | 2013 | Biomacromolecules | pmid:23550841 |
| Khan AA et al. | Design, synthesis and in vitro anticancer evaluation of a stearic acid-based ester conjugate. | 2013 | Anticancer Res. | pmid:23749903 |
| Li C et al. | Enhanced performance and interfacial investigation of mineral-based composite phase change materials for thermal energy storage. | 2013 | Sci Rep | pmid:23712069 |
| Lakio S et al. | Challenges in detecting magnesium stearate distribution in tablets. | 2013 | AAPS PharmSciTech | pmid:23378252 |
| Järvinen MA et al. | Continuous direct tablet compression: effects of impeller rotation rate, total feed rate and drug content on the tablet properties and drug release. | 2013 | Drug Dev Ind Pharm | pmid:23163644 |
| Schrank S et al. | Microstructure of calcium stearate matrix pellets: a function of the drying process. | 2013 | J Pharm Sci | pmid:23983150 |
| Yang C et al. | Production of aviation fuel via catalytic hydrothermal decarboxylation of fatty acids in microalgae oil. | 2013 | Bioresour. Technol. | pmid:23973977 |
| Barber E et al. | Comparative actions of omega-3 fatty acids on in-vitro lipid droplet formation. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:24012207 |
| Cunha TA et al. | Effect of stearic acid on enalapril stability and dissolution from multiparticulate solid dosage forms. | 2013 | AAPS PharmSciTech | pmid:23897034 |
| Jaumot J et al. | Blending process modeling and control by multivariate curve resolution. | 2013 | Talanta | pmid:24209372 |
| Uchimoto T et al. | Determination of useful ranges of mixing conditions for glycerin Fatty Acid ester by multiple regression analysis. | 2013 | Chem. Pharm. Bull. | pmid:24189302 |
| Tsuchiya A et al. | Stearic acid serves as a potent inhibitor of protein tyrosine phosphatase 1B. | 2013 | Cell. Physiol. Biochem. | pmid:24296476 |
| Shibata E et al. | Free fatty acids inhibit protein tyrosine phosphatase 1B and activate Akt. | 2013 | Cell. Physiol. Biochem. | pmid:24107614 |
| Høstmark AT et al. | Increased serum triglycerides and reduced HDL cholesterol in male rats after intake of ammonium chloride for 3 weeks. | 2013 | Lipids Health Dis | pmid:23800210 |
| Zhang W et al. | Stearylated antimicrobial peptide melittin and its retro isomer for efficient gene transfection. | 2013 | Bioconjug. Chem. | pmid:24107137 |
| Saroja C and Lakshmi PK | Formulation and optimization of fenofibrate lipospheres using Taguchi's experimental design. | 2013 | Acta Pharm | pmid:23482314 |
| Pethrick RA and Song M | Dielectric studies of amylose, amylopectin and amylose-stearic acid complexes. | 2013 | Carbohydr Polym | pmid:23399185 |
| Neupane YR et al. | Lipid drug conjugate nanoparticle as a novel lipid nanocarrier for the oral delivery of decitabine: ex vivo gut permeation studies. | 2013 | Nanotechnology | pmid:24061410 |
| Yan J et al. | Effect of proteins with different isoelectric points on the gene transfection efficiency mediated by stearic acid grafted chitosan oligosaccharide micelles. | 2013 | Mol. Pharm. | pmid:23679858 |
| Kwan HY et al. | The anticancer effect of oridonin is mediated by fatty acid synthase suppression in human colorectal cancer cells. | 2013 | J. Gastroenterol. | pmid:22722903 |
| Subbaramaiah K et al. | Dietary polyphenols suppress elevated levels of proinflammatory mediators and aromatase in the mammary gland of obese mice. | 2013 | Cancer Prev Res (Phila) | pmid:23880231 |