stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Larsson K and Glantz PO | Microbial adhesion to surfaces with different surface charges. | 1981 | Acta Odontol. Scand. | pmid:6948486 |
Gorrissen H et al. | Deuterium magnetic resonance of selectively deuterated cholesteryl esters in dipalmitoyl phosphatidylcholine dispersions. | 1981 | Biochim. Biophys. Acta | pmid:6894863 |
Broekman MJ et al. | Fatty acid composition of phosphatidylinositol and phosphatidic acid in stimulated platelets. Persistence of arachidonyl-stearyl structure. | 1981 | J. Biol. Chem. | pmid:6790536 |
Bonini de Romanelli IC et al. | Phosphatidic acid, phosphatidylinositol, phosphatidylserine and cardiolipin in the course of early embryonic development. Fatty acid composition and content in whole toad embryos and in mitochondrial fractions. | 1981 | Biochim. Biophys. Acta | pmid:6791698 |
Yamauchi T et al. | Thermal adaptation of Tetrahymena membranes with special reference to mitochondria. Role of cardiolipin in fluidity of mitochondrial membranes. | 1981 | Biochim. Biophys. Acta | pmid:6797472 |
Walsh C et al. | Arachidonate metabolism by neutrophils. | 1981 | Prog. Lipid Res. | pmid:6804984 |
McGimpsey JG et al. | Comparison of serum erythromycin concentration following administration of 100 mg erythromycin ethyl succinate intramuscularly and 500 mg erythromycin stearate orally. | 1981 | Int J Oral Surg | pmid:6807878 |
Teyssier G et al. | [Adult-type respiratory distress syndrome in children. Course of the palmitic acid/stearic acid ratio in tracheal aspirations]. | 1981 | Nouv Presse Med | pmid:7290945 |
Alam AS and Gregoriades D | Physicochemical properties of magnesium salicylate. | 1981 | J Pharm Sci | pmid:7310674 |
Królikowska-Prasał I and Zakrzewska-Grzycka T | Histochemical studies of the liver in acute and chronic lead stearate poisoning. | 1981 | Ann Univ Mariae Curie Sklodowska Med | pmid:7052786 |
Smaby JM and Brockman HL | Novel surface phase containing cholesteryl esters. 2. Nonequivalence of cholesteryl arachidonate and those with 18-carbon, cis-unsaturated acyl groups. | 1981 | Biochemistry | pmid:7213606 |
Rosenthal MD | Accumulation of neutral lipids by human skin fibroblasts: differential effects of saturated and unsaturated fatty acids. | 1981 | Lipids | pmid:7219087 |
Naggar VF | An in vitro study of the interaction between diazepam and some antacid or excipients. | 1981 | Pharmazie | pmid:7232481 |
Holub BJ | The suitability of different acyl acceptors as substrates for the acyl-Coa : 2-acyl-sn-glycero-3-phosphorylcholine acyltransferase in rat liver microsomes. | 1981 | Biochim. Biophys. Acta | pmid:7248321 |
Iliopoulou A et al. | Fluorimetric and microbiological assays of erythromycin concentrations in plasma and vaginal washings. | 1981 | Br J Vener Dis | pmid:7272705 |
Walzthöny D et al. | Ice crystals specifically decorate hydrophilic sites on freeze-fractured models membranes. | 1981 | Ultramicroscopy | pmid:7281365 |
Albanese A et al. | [Preparation of patients in diagnostic contrast radiography of the urinary and bile tracts and the large intestine]. | 1981 | Minerva Med. | pmid:7290472 |
Faas FH and Carter WJ | Fatty-acid desaturation and microsomal lipid fatty-acid composition in experimental hyperthyroidism. | 1981 | Biochem. J. | pmid:7305962 |
Mather LE et al. | Absorption and bioavailability of oral erythromycin. | 1981 | Br J Clin Pharmacol | pmid:7306427 |
Baker RR and Chang HY | A comparison of lysophosphatidylcholine acyltransferase activities in neuronal nuclei and microsomes isolated from immature rabbit cerebral cortex. | 1981 | Biochim. Biophys. Acta | pmid:7306562 |
Eriksson M et al. | Absorption of erythromycin from pediatric suspension in infants and children. | 1981 | Scand. J. Infect. Dis. | pmid:7313575 |
Clayton D and Leslie A | The bioavailability of erythromycin stearate versus enteric-coated erythromycin base when taken immediately before and after food. | 1981 | J. Int. Med. Res. | pmid:7319133 |
Benes B and Bencko V | Content of lipids and esterified fatty acids in the liver of mice exposed to arsenic in drinking water. | 1981 | J Hyg Epidemiol Microbiol Immunol | pmid:7320503 |
Bolhuis GK et al. | Interaction of tablet disintegrants and magnesium stearate during mixing I: Effect on tablet disintegration. | 1981 | J Pharm Sci | pmid:7320846 |
Hsia JC and Kwan NH | Human serum albumin: binding specificity and allosteric effect of parinarate and stearate. A dianionic spin label study. | 1981 | J. Biol. Chem. | pmid:6257712 |
Kudoh T et al. | Metabolism of fatty acid-labeled cerebroside sulfate in cultured cells from controls and metachromatic leukodystrophy patients. Use in the prenatal identification of a false positive fetus. | 1981 | J. Lab. Clin. Med. | pmid:6117597 |
Mesiha MS and El-Bitar HI | Hypoglycaemic effect of oral insulin preparations containing Brij 35, 52, 58 or 92 and stearic acid. | 1981 | J. Pharm. Pharmacol. | pmid:6118416 |
Yue KT et al. | Effect of glucose on plasma concentrations of individual non-esterified fatty acids of non-diabetic and insulin-independent diabetic men. | 1981 | Postgrad Med J | pmid:7335561 |
Sugita M et al. | Studies on glycosphingolipids of fresh-water bivalves. VI. Isolation and chemical characterization of neutral glycosphingolipids from spermatozoa of the fresh-water bivalve, Hyriopsis schlegelii. | 1981 | J. Biochem. | pmid:7338520 |
Haley K et al. | Optimal milk penicillin levels for the treatment of experimentally induced mastitis in cows. | 1981 | Can. J. Comp. Med. | pmid:7340909 |
Branigan TA et al. | The effects of erythromycin on the absorption and disposition of kinetics of theophylline. | 1981 | Eur. J. Clin. Pharmacol. | pmid:7341279 |
Prescott SM and Majerus PW | The fatty acid composition of phosphatidylinositol from thrombin-stimulated human platelets. | 1981 | J. Biol. Chem. | pmid:7451460 |
Cochran FB et al. | Myelin gangliosides: an unusual pattern in the avian central nervous system. | 1981 | J. Neurochem. | pmid:7463084 |
Bleeker J et al. | Effect of systemic erythromycin stearate on the inflammatory lesions and skin surface fatty acids in acne vulgaris. | 1981 | Dermatologica | pmid:6454598 |
Roshanai F et al. | Prostaglandin precursors in platelet phosphoglycerides following acute myocardial infarction. | 1981 Oct 1-15 | Thromb. Res. | pmid:6277036 |
Loi F and Amati R | [Lead-stearate exposure in a plastic factory in the province of Siena (author's transl)]. | 1981 Sep-Oct | Med Lav | pmid:7322018 |
Aprahamian SA et al. | Comparative studies on the kinetic parameters and product analyses of chicken and rat liver and yeast fatty acid synthetase. | 1982 | Comp. Biochem. Physiol., B | pmid:7044669 |
Jacques NA | Relationship between cyclopropane synthetase and the formation of cyclopropane fatty acids by Proteus vulgaris grown under various respiratory conditions. | 1982 | J. Gen. Microbiol. | pmid:7045282 |
Wei TC | Quantitative determination of chemical composition of gallstones by infrared absorption spectrophotometry. | 1982 | Taiwan Yi Xue Hui Za Zhi | pmid:6954245 |
Slomiany BL et al. | Lipid composition of the matrix of human submandibular salivary gland stones. | 1982 | Arch. Oral Biol. | pmid:6958224 |
Goto M et al. | Evidence for a correlation between swimming velocity and membrane fluidity of Tetrahymena cells. | 1982 | Biochim. Biophys. Acta | pmid:6818990 |
Moore KH et al. | beta-Hydroxy fatty acid production by ischemic rabbit heart. | 1982 | J. Clin. Invest. | pmid:6799549 |
Woodward H et al. | Isolation, purification, and properties of respiratory mucus glycoproteins. | 1982 | Biochemistry | pmid:7074033 |
Katz AM et al. | Fatty acid effects on calcium influx and efflux in sarcoplasmic reticulum vesicles from rabbit skeletal muscle. | 1982 | Biochim. Biophys. Acta | pmid:7074105 |
Bridges CD et al. | Vitamin A in human eyes: amount, distribution, and composition. | 1982 | Invest. Ophthalmol. Vis. Sci. | pmid:7076416 |
Lehmann J and McGill M | Biochemical and ultrastructural alterations in platelets, reticulocytes, and lymphocytes from rats fed vitamin E-deficient diets. | 1982 | J. Lipid Res. | pmid:7077144 |
Josefsson K et al. | Dose-related pharmacokinetics after oral administration of a new formulation of erythromycin base. | 1982 | Br J Clin Pharmacol | pmid:7082537 |
NadtochiÄ VV and BrodskiÄ RA | [Absorption study of 3H-stearic acid in the rat small intestine using electron microscopic autoradiography]. | 1982 | Tsitologiia | pmid:7135486 |
Chen SC et al. | Calorimetric evidence for phase transitions in spin-label lipid bilayers. | 1982 | Biochemistry | pmid:7138849 |
Mroso PV et al. | Solid-state stability of aspirin in the presence of excipients: kinetic interpretation, modeling, and prediction. | 1982 | J Pharm Sci | pmid:7143203 |