stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Wei TC | Quantitative determination of chemical composition of gallstones by infrared absorption spectrophotometry. | 1982 | Taiwan Yi Xue Hui Za Zhi | pmid:6954245 |
Slomiany BL et al. | Lipid composition of the matrix of human submandibular salivary gland stones. | 1982 | Arch. Oral Biol. | pmid:6958224 |
Tinsley IJ et al. | Tissue fatty acid changes and tumor incidence in C3H mice ingesting cottonseed oil. | 1982 | Lipids | pmid:6896358 |
Goto M et al. | Evidence for a correlation between swimming velocity and membrane fluidity of Tetrahymena cells. | 1982 | Biochim. Biophys. Acta | pmid:6818990 |
Moore KH et al. | beta-Hydroxy fatty acid production by ischemic rabbit heart. | 1982 | J. Clin. Invest. | pmid:6799549 |
Hong SL and Deykin D | Activation of phospholipases A2 and C in pig aortic endothelial cells synthesizing prostacyclin. | 1982 | J. Biol. Chem. | pmid:6806265 |
Eccleston GM | The influence of fatty alcohols on the structure and stability of creams prepared with polyethylene glycol 1000 monostearate/fatty alcohols. | 1982 | Int J Cosmet Sci | pmid:19469959 |
Perkins RC et al. | Equilibrium binding of spin-labeled fatty acids to bovine serum albumin: suitability as surrogate ligands for natural fatty acids. | 1982 | Biochemistry | pmid:6289869 |
Akesson B | Content of phospholipids in human diets studied by the duplicate-portion technique. | 1982 | Br. J. Nutr. | pmid:7066286 |
Holub BJ | The relative deacylation of different molecular species of endogenous phosphatidylethanolamine in rat liver microsomes by phospholipase activity. | 1982 | Biochim. Biophys. Acta | pmid:7093298 |
Pritzker KP et al. | Adrenal and hepatic calcium stearate crystal deposits in dogs fed a thiamine-deficient diet. | 1982 | Am. J. Vet. Res. | pmid:7103233 |
Huang YS et al. | Tissue lipids in acute acrylamide intoxicated rats. | 1982 | Can J Neurol Sci | pmid:7104883 |
Townsend LE et al. | In vitro acylation of rat brain myelin proteolipid protein. | 1982 | J. Biol. Chem. | pmid:7107590 |
NadtochiÄ VV and BrodskiÄ RA | [Absorption study of 3H-stearic acid in the rat small intestine using electron microscopic autoradiography]. | 1982 | Tsitologiia | pmid:7135486 |
Chen SC et al. | Calorimetric evidence for phase transitions in spin-label lipid bilayers. | 1982 | Biochemistry | pmid:7138849 |
Mroso PV et al. | Solid-state stability of aspirin in the presence of excipients: kinetic interpretation, modeling, and prediction. | 1982 | J Pharm Sci | pmid:7143203 |
Katz AM and Messineo FC | Fatty acid effects on membranes: possible role in the pathogenesis of ischemic myocardial damage. | 1982 | J. Mol. Cell. Cardiol. | pmid:7143451 |
Lerk CF et al. | Interaction of tablet disintegrants and magnesium stearate during mixing. II. Effect on dissolution rate. | 1982 | Pharm Acta Helv | pmid:7146030 |
Warner T and Zar JH | Fatty acid composition of brown fat and brain fat of the little brown bat, Myotis lucifugus, during hibernation. | 1982 | Comp. Biochem. Physiol., B | pmid:7151405 |
Iliopoulou A et al. | Should erythromycin dose be altered in haemodialysis patients? | 1982 | Eur. J. Clin. Pharmacol. | pmid:7151848 |
Faas FH and Carter WJ | Fatty acid desaturation and microsomal lipid fatty acid composition in experimental hypothyroidism. | 1982 | Biochem. J. | pmid:7181859 |
Bazan NG et al. | High content of 22:6 (docosahexaenoate) and active [2-3H]glycerol metabolism of phosphatidic acid from photoreceptor membranes. | 1982 | Biochim. Biophys. Acta | pmid:6215065 |
Nozawa CM and Apostolov K | Increase in the saturation of C18 fatty acids induced by coxsackie B6 virus in Vero cells. | 1982 | Virology | pmid:6285601 |
May DC et al. | The effects of erythromycin on theophylline elimination in normal males. | 1982 Feb-Mar | J Clin Pharmacol | pmid:7068935 |
della Ventura A and della Ventura D | [Clinical experiments with erythromycin stearate in surgery of the oral cavity]. | 1982 May-Jun | Odontostomatol Implantoprotesi | pmid:6984149 |
Oriel JD et al. | Treatment of gonococcal urethritis in men with a rifampicin-erythromycin combination. | 1982 Oct-Dec | Sex Transm Dis | pmid:6821502 |
Rosenthal MD and Whitehurst MC | Selective effects of isomeric cis and trans fatty acids on fatty acyl delta 9 and delta 6 desaturation by human skin fibroblasts. | 1983 | Biochim. Biophys. Acta | pmid:6615875 |
Hwang CC and Danti AG | Percutaneous absorption of flufenamic acid in rabbits: effect of dimethyl sulfoxide and various nonionic surface-active agents. | 1983 | J Pharm Sci | pmid:6620136 |
Philip J and Daly RE | Test for selection of erythromycin stearate bulk drug for tablet preparation. | 1983 | J Pharm Sci | pmid:6620167 |
Shih JC and Ohsawa R | Differential effect of cholesterol on two types of 5-hydroxytryptamine binding sites. | 1983 | Neurochem. Res. | pmid:6621769 |
van Kamp HV et al. | Improvement by super disintegrants of the properties of tablets containing lactose, prepared by wet granulation. | 1983 | Pharm Weekbl Sci | pmid:6622211 |
Warhurst DC et al. | The blood schizontocidal action of erythromycin against Plasmodium knowlesi infections in Macaca mulatta. | 1983 | Ann Trop Med Parasitol | pmid:6625724 |
Saatov TS et al. | [Content, intensity of exchange, and metabolic interaction of phospholipids and glycolipids in various tissues in experimental diabetes]. | 1983 | Biokhimiia | pmid:6671113 |
Kushi Y et al. | Comparative study of acidic glycosphingolipids by field desorption and secondary ion mass spectrometry. | 1983 | J. Biochem. | pmid:6671968 |
Green B et al. | Qualitative and quantitative changes in milk fat during lactation in the tammar wallaby (Macropus eugenii). | 1983 | Aust. J. Biol. Sci. | pmid:6675645 |
Tulenko TN and Rabinowitz JL | Metabolism of C14 mevalonate by adult and fetal arteries. | 1983 | Artery | pmid:6677248 |
Chien JL and Hogan EL | Novel pentahexosyl ganglioside of the globo series purified from chicken muscle. | 1983 | J. Biol. Chem. | pmid:6885798 |
Pethick DW et al. | The metabolism of circulating non-esterified fatty acids by the whole animal, hind-limb muscle and uterus of pregnant ewes. | 1983 | Br. J. Nutr. | pmid:6821682 |
Slomiany A et al. | Covalently linked fatty acids in gastric mucus glycoprotein of cystic fibrosis patients. | 1983 | J. Biol. Chem. | pmid:6863300 |
Khan KA et al. | The effect of mixing time of magnesium stearate on the tableting properties of dried microcrystalline cellulose. | 1983 | Pharm Acta Helv | pmid:6867042 |
Shanson DC et al. | High dose oral erythromycin for preventing endocarditis. | 1983 | Lancet | pmid:6130318 |
de Haan P and Kalsbeek GL | Humoral immune response to some benzylpenicillin preparations. | 1983 | Allergy | pmid:6412583 |
Anderton P et al. | Measles-virus-persistent infection in BGM cells. Modification of the incorporation of [3H]arachidonic acid and [14C]stearic acid into lipids. | 1983 | Biochem. J. | pmid:6414459 |
Süss W | [Production of delayed-release formulations based on hydrophilic matrix forms using polyvinyl alcohol]. | 1983 | Pharmazie | pmid:6415679 |
Bascoul J et al. | Preparation of autoxidized cholesterol mixtures from [4-14C] cholesterol and cholesteryl fatty acid esters. | 1983 | J. Steroid Biochem. | pmid:6423895 |
Kemp P and Lander DJ | The hydrogenation of gamma-linolenic acid by pure cultures of two rumen bacteria. | 1983 | Biochem. J. | pmid:6318740 |
Gabriel SM and Simpkins JW | Effects of a sustained-release naloxone pellet on luteinizing hormone secretion in female rats. | 1983 | Neuroendocrinology | pmid:6139759 |
Jacques NA | Membrane perturbation by cerulenin modulates glucosyltransferase secretion and acetate uptake by Streptococcus salivarius. | 1983 | J. Gen. Microbiol. | pmid:6229601 |
Agrawal HC et al. | In vivo incorporation of [3H]palmitic acid into PO protein, the major intrinsic protein of rat sciatic nerve myelin. | 1983 | J. Biol. Chem. | pmid:6189827 |
Neufeld EJ et al. | High affinity esterification of eicosanoid precursor fatty acids by platelets. | 1983 | J. Clin. Invest. | pmid:6308046 |