stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Stanisz B | The influence of pharmaceutical excipients on quinapril hydrochloride stability. | 2005 May-Jun | Acta Pol Pharm | pmid:16193811 |
Hussain T et al. | Effect of two hydrophobic polymers on the release of gliclazide from their matrix tablets. | 2013 Jul-Aug | Acta Pol Pharm | pmid:23923399 |
Stanisz B et al. | Influence of humidity and hydroxypropyl cellulose, hydroxypropylmethyl cellulose, glyceryl behenate or magnesium stearate on the degradation kinetics of quinapril hydrochloride in solid phase. | 2010 Jan-Feb | Acta Pol Pharm | pmid:20210086 |
MuzÃková J et al. | A study of micronized poloxamers as lubricants in direct compression of tablets. | 2013 Nov-Dec | Acta Pol Pharm | pmid:24383332 |
Kerti A et al. | Content of retinol and retinyl esters in blood plasma, liver, kidney and reproductive organs of Japanese quails. | 2002 | Acta Vet. Hung. | pmid:12498148 |
Fodorová M et al. | Structural features of lipid A of Rickettsia typhi. | 2011 | Acta Virol. | pmid:21434703 |
Bertrand G et al. | [The value of polyglactin 910 combined with a resorbable bone wax for filling periodontal bone defects]. | 1985 | Actual Odontostomatol (Paris) | pmid:2425560 |
Veit M and Thaa B | Association of influenza virus proteins with membrane rafts. | 2011 | Adv Virol | pmid:22312341 |
Nishioka Y and Yoshino H | Lymphatic targeting with nanoparticulate system. | 2001 | Adv. Drug Deliv. Rev. | pmid:11251245 |
Jensen RG et al. | Parenteral infusion of a lactating woman with intralipid: changes in milk and plasma fatty acids. | 2001 | Adv. Exp. Med. Biol. | pmid:11787679 |