stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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FUTTERMAN S and ANDREWS JS | THE FATTY ACID COMPOSITION OF HUMAN RETINAL VITAMIN A ESTER AND THE LIPIDS OF HUMAN RETINAL TISSUE. | 1964 | Invest Ophthalmol | pmid:14203336 |
BERGELSON LD et al. | COMPLETE STRUCTURAL ANALYSIS OF FATTY ACID MIXTURES BY THIN-LAYER CHROMATOGRAPHY. | 1964 | J. Chromatogr. | pmid:14205937 |
HAMMONDS TW and SHONE G | THE SEPARATION OF FATTY ACID METHYL ESTERS (INCLUDING "CRITICAL PAIRS") BY THIN-LAYER PARTITION CHROMATOGRAPHY. | 1964 | J. Chromatogr. | pmid:14205938 |
PILZ H and JATZKEWITZ H | [DETERMINATION OF C18- AND C24-SPHINGOMYELIN BY THIN-LAYER CHROMATOGRAPHY IN NORMAL AND PATHOLOGICAL BRAINS, INCLUDING A CASE OF NIEMANN-PICK DISEASE]. | 1964 | J. Neurochem. | pmid:14206462 |
ELLEFSON RD and MASON HL | EFFECTS OF DEFICIENCY AND EXCESS OF THYROID HORMONE ON THE DISTRIBUTION OF FATTY ACIDS IN LIPIDS OF THE RAT. | 1964 | Endocrinology | pmid:14206987 |
ROWE CE | THE OCCURRENCE AND METABOLISM IN VITRO OF UNESTERIFIED FATTY ACID IN MOUSE BRAIN. | 1964 | Biochim. Biophys. Acta | pmid:14230816 |
KELLERMAN GM and JOLLOW DJ | CONVERSION OF STEARIC ACID INTO OLEIC ACID IN ADIPOSE TISSUE. | 1964 | Biochim. Biophys. Acta | pmid:14230826 |
WILLEBRANDS AF | MYOCARDIAL EXTRACTION OF INDIVIDUAL NON-ESTERIFIED FATTY ACIDS, ESTERIFIED FATTY ACIDS AND ACETOACETATE IN THE FASTING HUMAN. | 1964 | Clin. Chim. Acta | pmid:14230940 |
SKIPSKI VP and MOREHOUSE MG | THE INCORPORATION OF INGESTED GLYCEROL-C14 INTO THE LIPIDS ON THE RAT. | 1964 | Arch. Biochem. Biophys. | pmid:14234504 |
HOLLOWAY PW and WAKIL SJ | SYNTHESIS OF FATTY ACIDS IN ANIMAL TISSUES. II. THE OCCURRENCE AND BIOSYNTHESIS OF CIS-VACCENIC ACID. | 1964 | J. Biol. Chem. | pmid:14235526 |
DAVIDOFF F and KORN ED | THE CONVERSION OF LONG CHAIN SATURATED FATTY ACIDS TO THEIR ALPHA, BETA-UNSATURATED, BETA, GAMMA-UNSATURATED, AND BETA-HYDROXY DERIVATIVES BY ENZYMES FROM THE CELLULAR SLIME MOLD, DICTYOSTELIUM DISCOIDEUM. | 1964 | J. Biol. Chem. | pmid:14235527 |
BRYAN GT et al. | IN VIVO ELUTION OF TRYPTOPHAN METABOLITES AND OTHER AROMATIC NITROGEN COMPOUNDS FROM CHOLESTEROL PELLETS IMPLANTED INTO MOUSE BLADDERS. | 1964 | Cancer Res. | pmid:14188460 |
KAKEMI K et al. | [STUDIES ON SUCROSE ESTERS. 3. EFFECT OF SUCROSE ESTERS ON THE ABSORPTION OF DRUGS FROM THE ALIMENTARY TRACT]. | 1964 | Yakugaku Zasshi | pmid:14266554 |
TIETZ A et al. | A NEW PTERIDINE-REQUIRING ENZYME SYSTEM FOR THE OXIDATION OF GLYCERYL ETHERS. | 1964 | J. Biol. Chem. | pmid:14247652 |
OVERATH P and STUMPF PK | FAT METABOLISM IN HIGHER PLANTS. 23. PROPERTIES OF A SOLUBLE FATTY ACID SYNTHETASE FROM AVOCADO MESOCARP. | 1964 | J. Biol. Chem. | pmid:14247655 |
TOVE SB | TOXICITY OF SATURATED FAT. | 1964 | J. Nutr. | pmid:14227501 |
CLAYTON RB et al. | THE INTESTINAL ABSORPTION OF CHOLESTEROL, ITS ESTERS AND SOME RELATED STEROLS AND ANALOGUES IN THE ROAC, EURYCOTIS FLORIDANA. | 1964 | Comp. Biochem. Physiol. | pmid:14167530 |
PREISS B and BLOCH K | OMEGA-OXIDATION OF LONG CHAIN FATTY ACIDS IN RAT LIVER. | 1964 | J. Biol. Chem. | pmid:14114877 |
HOAK JC | STRUCTURE OF THROMBI PRODUCED BY INJECTIONS OF FATTY ACIDS. | 1964 | Br J Exp Pathol | pmid:14119273 |
ENGELMANN D et al. | [CONCERNING THE RESORPTION AND METABOLISM OF SOME 1-14C-LABELLED FREE FATTY ACIDS IN YOUNG RABBITS]. | 1964 | Clin. Chim. Acta | pmid:14122499 |