stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
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What lipids are associated with stearic acid?
Related references are published most in these journals:
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Han GR and Jang CH | Detection of heavy-metal ions using liquid crystal droplet patterns modulated by interaction between negatively charged carboxylate and heavy-metal cations. | 2014 | Talanta | pmid:25059128 |
| Igne B et al. | Modeling strategies for pharmaceutical blend monitoring and end-point determination by near-infrared spectroscopy. | 2014 | Int J Pharm | pmid:25003830 |
| Syamala US et al. | Assessment of formulation factors on the release behaviour of BCS Class II drug from tablet dosage form using DoE. | 2014 | Curr Drug Deliv | pmid:24975287 |
| Wu MH et al. | A novel sodium N-fatty acyl amino acid surfactant using silkworm pupae as stock material. | 2014 | Sci Rep | pmid:24651079 |
| Kumar SS et al. | Synthesis and characterization of curcumin loaded polymer/lipid based nanoparticles and evaluation of their antitumor effects on MCF-7 cells. | 2014 | Biochim. Biophys. Acta | pmid:24440669 |
| Wang J et al. | A soybean acyl carrier protein, GmACP, is important for root nodule symbiosis. | 2014 | Mol. Plant Microbe Interact. | pmid:24400939 |
| MuzÃková J et al. | A study of micronized poloxamers as lubricants in direct compression of tablets. | 2013 Nov-Dec | Acta Pol Pharm | pmid:24383332 |
| Aljaberi A et al. | Understanding and optimizing the dual excipient functionality of sodium lauryl sulfate in tablet formulation of poorly water soluble drug: wetting and lubrication. | 2013 Mar-Apr | Pharm Dev Technol | pmid:23009028 |
| Kushner J | Utilizing quantitative certificate of analysis data to assess the amount of excipient lot-to-lot variability sampled during drug product development. | 2013 Mar-Apr | Pharm Dev Technol | pmid:21877870 |
| Hussain T et al. | Effect of two hydrophobic polymers on the release of gliclazide from their matrix tablets. | 2013 Jul-Aug | Acta Pol Pharm | pmid:23923399 |
| MuzÃková J and Sináglová P | Comparison of properties of tablets and energy profile of compaction of two spray-dried lactoses. | 2013 Jan-Feb | Acta Pol Pharm | pmid:23610968 |
| Di Vaio C et al. | Influence of some environmental factors on drupe maturation and olive oil composition. | 2013 | J. Sci. Food Agric. | pmid:22936522 |
| Ruddle P et al. | Effect of a novel mutation in a Δ9-stearoyl-ACP-desaturase on soybean seed oil composition. | 2013 | Theor. Appl. Genet. | pmid:22961205 |
| Chu X et al. | Sterol regulatory element-binding protein-1c mediates increase of postprandial stearic acid, a potential target for improving insulin resistance, in hyperlipidemia. | 2013 | Diabetes | pmid:22966071 |
| Hu FQ et al. | Effective antitumor gene therapy delivered by polyethylenimine-conjugated stearic acid-g-chitosan oligosaccharide micelles. | 2013 | Gene Ther. | pmid:22951455 |
| Leskinen JT et al. | Real-time tablet formation monitoring with ultrasound measurements in eccentric single station tablet press. | 2013 | Int J Pharm | pmid:22985771 |
| Horio T et al. | Measurement of flowability of lubricated powders by the vibrating tube method. | 2013 | Drug Dev Ind Pharm | pmid:22781029 |
| Stanisz B et al. | Effect of pharmaceutical excipients on the stability of angiotensin-converting enzyme inhibitors in their solid dosage formulations. | 2013 | Drug Dev Ind Pharm | pmid:22348774 |
| Němcová-Fürstová V et al. | Caspase-2 and JNK activated by saturated fatty acids are not involved in apoptosis induction but modulate ER stress in human pancreatic β-cells. | 2013 | Cell. Physiol. Biochem. | pmid:23466956 |
| Sovány T et al. | Application of physicochemical properties and process parameters in the development of a neural network model for prediction of tablet characteristics. | 2013 | AAPS PharmSciTech | pmid:23413109 |
| Mirani ZA and Jamil N | Role of extra-cellular fatty acids in vancomycin induced biofilm formation by vancomycin resistant Staphylococcus aureus. | 2013 | Pak J Pharm Sci | pmid:23455211 |
| Vervaeck A et al. | Prilling of fatty acids as a continuous process for the development of controlled release multiparticulate dosage forms. | 2013 | Eur J Pharm Biopharm | pmid:23474381 |
| Risley DS et al. | Analysis of magnesium from magnesium stearate in pharmaceutical tablet formulations using hydrophilic interaction liquid chromatography with nano quantity analyte detection. | 2013 | J Pharm Biomed Anal | pmid:23474810 |
| Zamora-Rojas E et al. | Prediction of fatty acids content in pig adipose tissue by near infrared spectroscopy: at-line versus in-situ analysis. | 2013 | Meat Sci. | pmid:23793086 |
| Song W et al. | Importance of size and distribution of Ni nanoparticles for the hydrodeoxygenation of microalgae oil. | 2013 | Chemistry | pmid:23794421 |
| Qi B et al. | A Golgi and tonoplast localized S-acyl transferase is involved in cell expansion, cell division, vascular patterning and fertility in Arabidopsis. | 2013 | New Phytol. | pmid:23795888 |
| Podczeck F et al. | Investigations into the tensile failure of doubly-convex cylindrical tablets under diametral loading using finite element methodology. | 2013 | Int J Pharm | pmid:23834836 |
| Wang N et al. | The mechanism of hydrogen sulfide adsorption on fine rubber particle media (FRPM). | 2013 | J. Hazard. Mater. | pmid:23876257 |
| Mohamed IO | Lipase-catalyzed acidolysis of palm mid fraction oil with palmitic and stearic Fatty Acid mixture for production of cocoa butter equivalent. | 2013 | Appl. Biochem. Biotechnol. | pmid:23877586 |
| Vitturi DA et al. | Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase. | 2013 | J. Biol. Chem. | pmid:23878198 |
| Saeedi Vahdat A et al. | Ultrasonic approach for viscoelastic and microstructure characterization of granular pharmaceutical tablets. | 2013 | Int J Pharm | pmid:23820132 |
| Franc A et al. | [Content uniformity of warfarin-containing mixtures and tablets]. | 2013 | Ceska Slov Farm | pmid:24047147 |
| Li L et al. | Drug release characteristics from chitosan-alginate matrix tablets based on the theory of self-assembled film. | 2013 | Int J Pharm | pmid:23624081 |
| MužÃková J and Sináglová P | A study of a new co-processed dry binder based on spray-dried lactose and microcrystalline cellulose. | 2013 | Ceska Slov Farm | pmid:23961814 |
| Neutsch L et al. | UPEC biomimickry at the urothelial barrier: lectin-functionalized PLGA microparticles for improved intravesical chemotherapy. | 2013 | Int J Pharm | pmid:23628404 |
| Emken E | Human studies using isotope labeled fatty acids: answered and unanswered questions. | 2013 | J Oleo Sci | pmid:23648399 |
| Dangarembizi R et al. | Aloe ferox seed: a potential source of oil for cosmetic and pharmaceutical use. | 2013 | Nat Prod Commun | pmid:23678824 |
| Maia M et al. | A novel, direct, reagent-free method for the detection of beeswax adulteration by single-reflection attenuated total reflectance mid-infrared spectroscopy. | 2013 | Talanta | pmid:23598195 |
| Dhasaiyan P et al. | Influence of the sophorolipid molecular geometry on their self-assembled structures. | 2013 | Chem Asian J | pmid:23208802 |
| Baek JS and Cho CW | 2-Hydroxypropyl-β-cyclodextrin-modified SLN of paclitaxel for overcoming p-glycoprotein function in multidrug-resistant breast cancer cells. | 2013 | J. Pharm. Pharmacol. | pmid:23215690 |
| Hu P et al. | Genotoxicity evaluation of stearic acid grafted chitosan oligosaccharide nanomicelles. | 2013 | Mutat. Res. | pmid:23274307 |
| Wu X et al. | Alkanethiol-functionalized terahertz metamaterial as label-free, highly-sensitive and specific biosensor. | 2013 | Biosens Bioelectron | pmid:23261700 |
| Zhou X et al. | The effect of saturated fatty acids on methanogenesis and cell viability of Methanobrevibacter ruminantium. | 2013 | Archaea | pmid:23710130 |
| Gotoh K et al. | Evaluation of removal of model particulate and oily soils from poly(ethylene terephthalate) films by microscopic image analysis. | 2013 | J Oleo Sci | pmid:23391530 |
| Silberstein T et al. | Saturated fatty acid composition of human milk in Israel: a comparison between Jewish and Bedouin women. | 2013 | Isr. Med. Assoc. J. | pmid:23781748 |
| Ogata F et al. | Study on analysis of waste edible oil with deterioration and removal of acid value, carbonyl value, and free fatty acid by a food additive (calcium silicate). | 2013 | J Oleo Sci | pmid:23391535 |
| Ishida Y et al. | Fatty acid solubilizer from the oral disk of the blowfly. | 2013 | PLoS ONE | pmid:23326317 |
| Sharma P et al. | Structural insights into the dual strategy of recognition by peptidoglycan recognition protein, PGRP-S: structure of the ternary complex of PGRP-S with lipopolysaccharide and stearic acid. | 2013 | PLoS ONE | pmid:23326499 |
| Tükel S et al. | Optimization of lipase-catalyzed synthesis of fructose stearate using response surface methodology. | 2013 | Artif Cells Nanomed Biotechnol | pmid:23305558 |
| Lee W et al. | Intracellular Mycobacterium tuberculosis exploits host-derived fatty acids to limit metabolic stress. | 2013 | J. Biol. Chem. | pmid:23306194 |
| Wu JH et al. | Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. | 2013 | Circ Cardiovasc Genet | pmid:23362303 |
| Arukuusk P et al. | New generation of efficient peptide-based vectors, NickFects, for the delivery of nucleic acids. | 2013 | Biochim. Biophys. Acta | pmid:23357356 |
| Järvinen K et al. | In-line monitoring of the drug content of powder mixtures and tablets by near-infrared spectroscopy during the continuous direct compression tableting process. | 2013 | Eur J Pharm Sci | pmid:23313622 |
| Zhou QT et al. | Effect of surface coating with magnesium stearate via mechanical dry powder coating approach on the aerosol performance of micronized drug powders from dry powder inhalers. | 2013 | AAPS PharmSciTech | pmid:23196863 |
| Van Hoeck V et al. | Oocyte developmental failure in response to elevated nonesterified fatty acid concentrations: mechanistic insights. | 2013 | Reproduction | pmid:23108110 |
| Negi JS et al. | Development of solid lipid nanoparticles (SLNs) of lopinavir using hot self nano-emulsification (SNE) technique. | 2013 | Eur J Pharm Sci | pmid:23153618 |
| Nakagawa H et al. | Real-time monitoring of lubrication properties of magnesium stearate using NIR spectrometer and thermal effusivity sensor. | 2013 | Int J Pharm | pmid:23174413 |
| Otsuka Y et al. | Effects of polymorphic transformation on pharmaceutical properties of direct compressed tablets containing theophylline anhydrate bulk powder under high humidity. | 2013 | Colloids Surf B Biointerfaces | pmid:23178204 |
| Azordegan N et al. | Carcinogenesis alters fatty acid profile in breast tissue. | 2013 | Mol. Cell. Biochem. | pmid:23180247 |
| Delbecq F et al. | N-stearoyl amino acid derivatives: potent biomimetic hydro/organogelators as templates for preparation of gold nanoparticles. | 2013 | J Colloid Interface Sci | pmid:23089597 |
| Avalle P et al. | Interrogating erosion-based drug liberation phenomena from hydrophilic matrices using near infrared (NIR) spectroscopy. | 2013 | Eur J Pharm Sci | pmid:23059372 |
| Salazar J et al. | Application of the combinative particle size reduction technology H 42 to produce fast dissolving glibenclamide tablets. | 2013 | Eur J Pharm Sci | pmid:23587645 |
| Fernandes CP et al. | Triterpene esters and biological activities from edible fruits of Manilkara subsericea (Mart.) Dubard, Sapotaceae. | 2013 | Biomed Res Int | pmid:23509702 |
| You J et al. | Specific tumor delivery of paclitaxel using glycolipid-like polymer micelles containing gold nanospheres. | 2013 | Biomaterials | pmid:23510855 |
| John CT et al. | Formulating weakly basic HCl salts: relative ability of common excipients to induce disproportionation and the unique deleterious effects of magnesium stearate. | 2013 | Pharm. Res. | pmid:23512680 |
| Stank K and Steckel H | Physico-chemical characterisation of surface modified particles for inhalation. | 2013 | Int J Pharm | pmid:23518364 |
| Kumar N et al. | Salt dependent stability of stearic acid Langmuir-Blodgett films exposed to aqueous electrolytes. | 2013 | Langmuir | pmid:23565719 |
| Han SH et al. | Bioinspired self-assembled peptide nanofibers with thermostable multivalent α-helices. | 2013 | Biomacromolecules | pmid:23550841 |
| Khan AA et al. | Design, synthesis and in vitro anticancer evaluation of a stearic acid-based ester conjugate. | 2013 | Anticancer Res. | pmid:23749903 |
| Li C et al. | Enhanced performance and interfacial investigation of mineral-based composite phase change materials for thermal energy storage. | 2013 | Sci Rep | pmid:23712069 |
| Lakio S et al. | Challenges in detecting magnesium stearate distribution in tablets. | 2013 | AAPS PharmSciTech | pmid:23378252 |
| Järvinen MA et al. | Continuous direct tablet compression: effects of impeller rotation rate, total feed rate and drug content on the tablet properties and drug release. | 2013 | Drug Dev Ind Pharm | pmid:23163644 |
| Schrank S et al. | Microstructure of calcium stearate matrix pellets: a function of the drying process. | 2013 | J Pharm Sci | pmid:23983150 |
| Yang C et al. | Production of aviation fuel via catalytic hydrothermal decarboxylation of fatty acids in microalgae oil. | 2013 | Bioresour. Technol. | pmid:23973977 |
| Barber E et al. | Comparative actions of omega-3 fatty acids on in-vitro lipid droplet formation. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:24012207 |
| Cunha TA et al. | Effect of stearic acid on enalapril stability and dissolution from multiparticulate solid dosage forms. | 2013 | AAPS PharmSciTech | pmid:23897034 |
| Jaumot J et al. | Blending process modeling and control by multivariate curve resolution. | 2013 | Talanta | pmid:24209372 |
| Uchimoto T et al. | Determination of useful ranges of mixing conditions for glycerin Fatty Acid ester by multiple regression analysis. | 2013 | Chem. Pharm. Bull. | pmid:24189302 |
| Tsuchiya A et al. | Stearic acid serves as a potent inhibitor of protein tyrosine phosphatase 1B. | 2013 | Cell. Physiol. Biochem. | pmid:24296476 |
| Camacho-Chab JC et al. | Emulsifying activity and stability of a non-toxic bioemulsifier synthesized by Microbacterium sp. MC3B-10. | 2013 | Int J Mol Sci | pmid:24065097 |
| Asumadu-Mensah A et al. | Solid lipid dispersions: potential delivery system for functional ingredients in foods. | 2013 | J. Food Sci. | pmid:23865449 |
| Hagen RM et al. | Conjugated linoleate reduces prostate cancer viability whereas the effects of oleate and stearate are cell line-dependent. | 2013 | Anticancer Res. | pmid:24123008 |
| Guo H et al. | Self-assembled nanoparticles based on galactosylated O-carboxymethyl chitosan-graft-stearic acid conjugates for delivery of doxorubicin. | 2013 | Int J Pharm | pmid:24140544 |
| Cvetković Z et al. | Distribution of plasma fatty acids is associated with response to chemotherapy in non-Hodgkin's lymphoma patients. | 2013 | Med. Oncol. | pmid:24085546 |
| Jin Q et al. | A novel cationic microbubble coated with stearic acid-modified polyethylenimine to enhance DNA loading and gene delivery by ultrasound. | 2013 | PLoS ONE | pmid:24086748 |
| Eltayeb M et al. | Electrosprayed core-shell polymer-lipid nanoparticles for active component delivery. | 2013 | Nanotechnology | pmid:24164775 |
| Boshtam M et al. | Serum paraoxonase 1 activity is associated with fatty acid composition of high density lipoprotein. | 2013 | Dis. Markers | pmid:24167374 |
| Shibata E et al. | Free fatty acids inhibit protein tyrosine phosphatase 1B and activate Akt. | 2013 | Cell. Physiol. Biochem. | pmid:24107614 |
| Høstmark AT et al. | Increased serum triglycerides and reduced HDL cholesterol in male rats after intake of ammonium chloride for 3 weeks. | 2013 | Lipids Health Dis | pmid:23800210 |
| Zhang W et al. | Stearylated antimicrobial peptide melittin and its retro isomer for efficient gene transfection. | 2013 | Bioconjug. Chem. | pmid:24107137 |
| Saroja C and Lakshmi PK | Formulation and optimization of fenofibrate lipospheres using Taguchi's experimental design. | 2013 | Acta Pharm | pmid:23482314 |
| Pethrick RA and Song M | Dielectric studies of amylose, amylopectin and amylose-stearic acid complexes. | 2013 | Carbohydr Polym | pmid:23399185 |
| Li P et al. | Effect of non-esterified fatty acids on fatty acid metabolism-related genes in calf hepatocytes cultured in vitro. | 2013 | Cell. Physiol. Biochem. | pmid:24335176 |
| Wahl PR et al. | Inline monitoring and a PAT strategy for pharmaceutical hot melt extrusion. | 2013 | Int J Pharm | pmid:23911343 |
| Michailidou VN et al. | Anisotropic diffusion of concentrated hard-sphere colloids near a hard wall studied by evanescent wave dynamic light scattering. | 2013 | J Chem Phys | pmid:24182077 |
| Hosseini A et al. | Direct compression of cushion-layered ethyl cellulose-coated extended release pellets into rapidly disintegrating tablets without changes in the release profile. | 2013 | Int J Pharm | pmid:23892153 |
| Neupane YR et al. | Lipid drug conjugate nanoparticle as a novel lipid nanocarrier for the oral delivery of decitabine: ex vivo gut permeation studies. | 2013 | Nanotechnology | pmid:24061410 |
| Yan J et al. | Effect of proteins with different isoelectric points on the gene transfection efficiency mediated by stearic acid grafted chitosan oligosaccharide micelles. | 2013 | Mol. Pharm. | pmid:23679858 |
| Kwan HY et al. | The anticancer effect of oridonin is mediated by fatty acid synthase suppression in human colorectal cancer cells. | 2013 | J. Gastroenterol. | pmid:22722903 |
| Subbaramaiah K et al. | Dietary polyphenols suppress elevated levels of proinflammatory mediators and aromatase in the mammary gland of obese mice. | 2013 | Cancer Prev Res (Phila) | pmid:23880231 |