stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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MORRIS LJ | SEPARATION OF ISOMERIC LONG-CHAIN POLYHYDROXY ACIDS BY THIN-LAYER CHROMATOGRAPHY. | 1963 | J. Chromatogr. | pmid:14070998 |
MAHADEVAN S et al. | STUDIES ON METABOLISM OF VITAMIN A. 3. THE MODE OF ABSORPTION OF VITAMIN A ESTERS IN THE LIVING RAT. | 1963 | Biochem. J. | pmid:14071526 |
MAHADEVAN S et al. | STUDIES ON METABOLISM OF VITAMIN A. 4. STUDIES ON THE MODE OF ABSORPTION OF VITAMIN A BY RAT INTESTINE IN VITRO. | 1963 | Biochem. J. | pmid:14071527 |
CORRIN B | ALUMINIUM PNEUMOCONIOSIS. I. IN VITRO COMPARISON OF STAMPED ALUMINIUM POWDERS CONTAINING DIFFERENT LUBRICATING AGENTS AND A GRANULAR ALUMINIUM POWDER. | 1963 | Br J Ind Med | pmid:14072616 |
GOMPERTZ SM and SAMMONS HG | THE ORIGIN OF FAECAL LIPIDS. THE COMPOSITION OF FAECAL FATSIN HUMAN SUBJECTS. | 1963 | Clin. Chim. Acta | pmid:14063975 |
DEMPSKI RE et al. | Permeability of excised human keratin to lipid-soluble substances. II. | 1963 | J Pharm Sci | pmid:14026933 |
KAUNITZ H et al. | Studies of the generalized Shwartzman reaction produced by diet. IV. Ethyl ester fractions of cod liver oil and dihydroxystearic acid. | 1963 | Metab. Clin. Exp. | pmid:14031428 |
JOHNSON RC and GARY ND | NUTRITION OF LEPTOSPIRA POMONA. II. FATTY ACID REQUIREMENTS. | 1963 | J. Bacteriol. | pmid:14044026 |
HALL PF et al. | Synthesis of fatty acids by testicular tissue in vitro. | 1963 | Can J Biochem Physiol | pmid:13952129 |
HUEPER WC and PAYNE WW | Polyoxyethylene(8)stearate. Carcinogenic studies. | 1963 | Arch. Environ. Health | pmid:13955486 |
BIOZZI G et al. | [Stimulation and depression of the phagocytic function of the reticuloendothelial system by lipid emulsions. Relation to some immunological phenomena]. | 1963 | Rev Fr Etud Clin Biol | pmid:13968394 |
BONE GJ and PARENT G | Stearic acid, an essential growth factor for Trypanosoma cruzi. | 1963 | J. Gen. Microbiol. | pmid:13968755 |
BONSER GM et al. | A further study of bladder implantation in the mouse as a means of detecting carcinogenic activity: use of crushed paraffin wax or stearic acid as the vehicle. | 1963 | Br. J. Cancer | pmid:13968883 |
BAKER RW et al. | Fatty-acid composition of brain lecithins in multiple sclerosis. | 1963 | Lancet | pmid:13969172 |
EDWARDS CH et al. | CHROMATOGRAPHY ON COMPOUNDS OF BIOLOGICAL INTEREST OF GLASS FIBER, PARAFFIN-COATED, AND UNTREATED CELLULOSE PAPER. | 1963 | J. Chromatogr. | pmid:14045492 |
HIRSCH J | FACTICE CHROMATOGRAPHY: AN AUTOMATICALLY MONITORED, LIQUID-GEL SYSTEM FOR THE SEPARATION OF NONPOLAR LIPIDS. | 1963 | J. Lipid Res. | pmid:14167659 |
HEALD PJ and BADMAN HG | LIPID METABOLISM AND THE LAYING HEN. I. PLASMA-FREE FATTY ACIDS AND THE ONSET OF LAYING IN THE DOMESTIC FOWL. | 1963 | Biochim. Biophys. Acta | pmid:14067611 |
KERR SE and READ WW | THE FATTY ACID COMPONENTS OF POLYPHOSPHOINOSITIDE PREPARED FROM CALF BRAIN. | 1963 | Biochim. Biophys. Acta | pmid:14067624 |
ERWIN J and BLOCH K | POLYUNSATURATED FATTY ACIDS IN SOME PHOTOSYNTHETIC MICROORGANISMS. | 1963 | Biochem Z | pmid:14087318 |
CALI G et al. | [GAS CHROMATOGRAPHY RESEARCH ON THE FATTY ACIDS OF HUMAN ADIPOSE TISSUE]. | 1963 | Ric Sci 2 Ser Pt 2 Rend B | pmid:14123061 |