stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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WAYNE EJ et al. | The use of procaine penicillin with aluminium monostearate in adults. | 1949 | Br Med J | pmid:15407914 |
EMERY JL and ROSE LM | The use in children of procaine penicillin with aluminium monostearate. | 1949 | Br Med J | pmid:18145953 |
KITCHEN DK et al. | Serum concentrations following five treatment schedules with procaine penicillin in oil with aluminum monostearate. | 1949 | J. Invest. Dermatol. | pmid:18110581 |
RIES HE et al. | Adsorption-desorption isotherm studies of catalysts; nitrogen and stearic acid adsorption by supported catalysts and their components. | 1949 | J Phys Colloid Chem | pmid:18130458 |
LIEN ML and MILLER CE | Magnesium stearate; a comparative study of commercial samples. | 1948 | J Am Pharm Assoc Am Pharm Assoc | pmid:18865175 |
OULLET C and DUBOIS JT | [Not Available]. | 1948 | Can J Res | pmid:18913992 |
McKAY AF and BADER AR | The preparation and properties of the eight diastereoisomers of 9,10,12,13-tetrahydroxystearic acid. | 1948 | J. Org. Chem. | pmid:18917710 |
McKAY AF | Occurrence of stearic acid in bayberry tallow (wax). | 1948 | J. Org. Chem. | pmid:18917711 |
NIGHTINGALE G et al. | Effect of dihydroxystearic acid on vitamin K synthesis by rats. | 1947 | Arch Biochem | pmid:20291026 |
GREGORY JN and SPINK JA | Lubricating properties of molecular layers of stearic acid and calcium stearate on metal surfaces. | 1947 | Nature | pmid:20291788 |
WITTCOFF H and MILLER SE | Hydroxylated stearic acids; action of Prevost's reagent on oleic and elaidic esters; evidence for configuration of the hydroxy acids. | 1947 | J. Am. Chem. Soc. | pmid:18919716 |
SWERN D et al. | Unsaturated alcohol esters of the 9,10-dihydroxystearic acids; preparation of elaidyl alcohol. | 1946 | J. Am. Chem. Soc. | pmid:20995013 |
VOLD RD and PHILIPSON JM | The behavior of sodium stearate with cetane and water. | 1946 | J Phys Chem | pmid:21010917 |
Gadegbeku CA et al. | Insulin's actions on plasma free fatty acids are normal in patients with stage 2 to 3 chronic kidney disease. | J Am Soc Hypertens | pmid:20409874 | |
Klibanov AL et al. | Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow. | Contrast Media Mol Imaging | pmid:17191766 | |
Garg M et al. | Hepatic de novo lipogenesis in stable low-birth-weight infants during exclusive breast milk feedings and during parenteral nutrition. | JPEN J Parenter Enteral Nutr | pmid:15772384 | |
Adams ML et al. | Amphotericin B encapsulated in micelles based on poly(ethylene oxide)-block-poly(L-amino acid) derivatives exerts reduced in vitro hemolysis but maintains potent in vivo antifungal activity. | Biomacromolecules | pmid:12741794 | |
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Best CA et al. | Method to assess fatty acid ethyl ester binding to albumin. | Alcohol Alcohol. | pmid:16554377 |