stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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NadtochiÄ VV and BrodskiÄ RA | [Absorption study of 3H-stearic acid in the rat small intestine using electron microscopic autoradiography]. | 1982 | Tsitologiia | pmid:7135486 |
Cutler RR et al. | The effect of polyoxyethylene stearate (POES) on the growth of mycobacteria in radiometric 7H12 Middlebrook TB medium. | 1987 | Tubercle | pmid:3448797 |
Williams KJ et al. | The Mycobacterium tuberculosis β-oxidation genes echA5 and fadB3 are dispensable for growth in vitro and in vivo. | 2011 | Tuberculosis (Edinb) | pmid:21764638 |
Nielsen GD et al. | [Aspiration of talcum or powder containing zinc stearate by children]. | 1979 | Ugeskr. Laeg. | pmid:442270 |
Walzthöny D et al. | Ice crystals specifically decorate hydrophilic sites on freeze-fractured models membranes. | 1981 | Ultramicroscopy | pmid:7281365 |
Yim B et al. | Sonolysis of surfactants in aqueous solutions: an accumulation of solute in the interfacial region of the cavitation bubbles. | 2002 | Ultrason Sonochem | pmid:12219583 |
Mizukoshi Y et al. | Preparation of platinum nanoparticles by sonochemical reduction of the Pt(IV) ions: role of surfactants. | 2001 | Ultrason Sonochem | pmid:11105315 |
Colmano G et al. | Activated silver coatings for surgical implants. | 1979 | Va Med | pmid:316624 |
Veit M and Siche S | S-acylation of influenza virus proteins: Are enzymes for fatty acid attachment promising drug targets? | 2015 | Vaccine | pmid:26387429 |
Lavergne SN et al. | Potential cutaneous hypersensitivity reaction to an inactive ingredient of thyroid hormone supplements in a dog. | 2016 | Vet. Dermatol. | pmid:26748887 |