stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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Robles Valderrama E et al. | [Application of gas chromatography in the identification of Enterobacter cloacae, Enterobacter aerogenes, and Enterobacter agglomerans]. | 1999 Jan-Mar | Rev. Latinoam. Microbiol. | pmid:10932747 |
Siaan M et al. | Influence of Avicel PH-301 on the compressibility of alpha-methyldopa and phenobarbitone in direct compression. | 2000 | Drug Dev Ind Pharm | pmid:10914328 |
Lee WN et al. | Loss of regulation of lipogenesis in the Zucker diabetic (ZDF) rat. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:10913044 |
Vashchuk VV and Vashchuk VV | [The use of the catalase P-47 preparation for treating long-term nonhealing wounds and trophic ulcers]. | 1993 | Klin Khir | pmid:10912018 |
Russo LI and Ghaly ES | Drug release from Carbomer 934 matrices. | 2000 | P R Health Sci J | pmid:10909708 |
Enjalbert F et al. | Effects of duodenal infusions of palmitic, stearic, or oleic acids on milk composition and physical properties of butter. | 2000 | J. Dairy Sci. | pmid:10908048 |
Bogataj M et al. | The influence of magnesium stearate on the characteristics of mucoadhesive microspheres. | 2000 Jul-Aug | J Microencapsul | pmid:10898089 |
Le Hénaff M and Fontenelle C | Chemical analysis of processing of spiralin, the major lipoprotein of Spiroplasma melliferum. | 2000 May-Jun | Arch. Microbiol. | pmid:10896212 |
Schweigert FJ and Bok V | Vitamin A in blood plasma and urine of dogs is affected by the dietary level of vitamin A. | 2000 | Int J Vitam Nutr Res | pmid:10883401 |
Robson H et al. | An investigation into the release of cefuroxime axetil from taste-masked stearic acid microspheres. III. The use of DSC and HSDSC as means of characterising the interaction of the microspheres with buffered media. | 2000 | Int J Pharm | pmid:10878327 |