stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
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What lipids are associated with stearic acid?
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Ebube NK et al. | Application of near-infrared spectroscopy for nondestructive analysis of Avicel powders and tablets. | 1999 | Pharm Dev Technol | pmid:10027209 |
| Zuurman K et al. | Effect of magnesium stearate on bonding and porosity expansion of tablets produced from materials with different consolidation properties. | 1999 | Int J Pharm | pmid:10053207 |
| Rukkwamsuk T et al. | Hepatic fatty acid composition in periparturient dairy cows with fatty liver induced by intake of a high energy diet in the dry period. | 1999 | J. Dairy Sci. | pmid:10068949 |
| Woldseth B et al. | Monounsaturated trans fatty acids, elaidic acid and trans-vaccenic acid, metabolism and incorporation in phospholipid molecular species in hepatocytes. | 1998 | Scand. J. Clin. Lab. Invest. | pmid:10088200 |
| Caster WO et al. | Effect of dietary palmitate, stearate, oleate and linoleate on the tissue lipid and systolic blood pressure of the rat. | 1976 | Int J Vitam Nutr Res | pmid:1010686 |
| Brown ST | Treatment of secondary syphilis. | 1976 | J Am Vener Dis Assoc | pmid:1010778 |
| Jarvis GN et al. | Isolation and characterization of two glycerol-fermenting clostridial strains from a pilot scale anaerobic digester treating high lipid-content slaughterhouse waste. | 1999 | J. Appl. Microbiol. | pmid:10196746 |
| Hannuksela M et al. | Contact sensitivity to emulsifiers. | 1976 | Contact Derm. | pmid:1021350 |
| Neumann D et al. | A comparison of sutures for adjustable strabismus surgery. | 1999 | J AAPOS | pmid:10221801 |
| Huang S et al. | Interleukin-1 stimulates Jun N-terminal/stress-activated protein kinase by an arachidonate-dependent mechanism in mesangial cells. | 1999 | Kidney Int. | pmid:10231436 |
| Pharmaceutical Reimbursement Board; final maximum allowable cost (MAC) determinations for certain drug products--Health Care Financing Administration. Final notice. | 1982 | Fed Regist | pmid:10259800 | |
| Horhota ST et al. | Effect of storage at specified temperature and humidity on properties of three directly compressible tablet formulations. | 1976 | J Pharm Sci | pmid:1032656 |
| Shen WW et al. | Effect of nonionic surfactants on percutaneous absorption of salicylic acid and sodium salicylate in the presence of dimethyl sulfoxide. | 1976 | J Pharm Sci | pmid:1032661 |
| Cavalli R et al. | Solid lipid nanoparticles as carriers of hydrocortisone and progesterone complexes with beta-cyclodextrins. | 1999 | Int J Pharm | pmid:10332075 |
| Müller WE | The use of 8-anilino-1-naphthalenesulfonic acid as a reporter group molecule for circular dichroism and fluorescence measurements. The effect of stearic acid and sodium dodecylsulfate on the conformation of bovine and human serum albumin. | 1976 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:1033907 |
| Jones AE et al. | Effect of fatty acid chain length and saturation on the gastrointestinal handling and metabolic disposal of dietary fatty acids in women. | 1999 | Br. J. Nutr. | pmid:10341674 |
| Bardi L et al. | Saccharomyces cerevisiae cell fatty acid composition and release during fermentation without aeration and in absence of exogenous lipids. | 1999 | Int. J. Food Microbiol. | pmid:10357281 |
| Alava MA et al. | Fatty acid desaturation: effect of alphafetoprotein on alpha-linolenic acid conversion by fetal rat hepatocytes. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10359023 |
| McKellop HA et al. | Effect of molecular weight, calcium stearate, and sterilization methods on the wear of ultra high molecular weight polyethylene acetabular cups in a hip joint simulator. | 1999 | J. Orthop. Res. | pmid:10376720 |
| Facciotti MT et al. | Improved stearate phenotype in transgenic canola expressing a modified acyl-acyl carrier protein thioesterase. | 1999 | Nat. Biotechnol. | pmid:10385326 |
| Crocker I et al. | Significance of fatty acids in pregnancy-induced immunosuppression. | 1999 | Clin. Diagn. Lab. Immunol. | pmid:10391868 |
| Hidaka T et al. | Screening of microbial products modifying the action of leptin (obese gene product) by a biosensor. | 1999 | J. Antibiot. | pmid:10395281 |
| Adachi T et al. | A novel Lyn-binding peptide inhibitor blocks eosinophil differentiation, survival, and airway eosinophilic inflammation. | 1999 | J. Immunol. | pmid:10395690 |
| Murakami K et al. | Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10403814 |
| Kelly FD et al. | Stearic acid-rich diets do not increase thrombotic risk factors in healthy males. | 1999 | Lipids | pmid:10419148 |
| Muszbek L et al. | The pool of fatty acids covalently bound to platelet proteins by thioester linkages can be altered by exogenously supplied fatty acids. | 1999 | Lipids | pmid:10419194 |
| Eliasen H et al. | Electrostatic charging during a melt agglomeration process. | 1999 | Int J Pharm | pmid:10425354 |
| Warnotte C et al. | Unbound rather than total concentration and saturation rather than unsaturation determine the potency of fatty acids on insulin secretion. | 1999 | Mol. Cell. Endocrinol. | pmid:10459862 |
| Eliasen H et al. | Growth mechanisms in melt agglomeration with a low viscosity binder. | 1999 | Int J Pharm | pmid:10486433 |
| Summers LK et al. | Use of structured triacylglycerols containing predominantly stearic and oleic acids to probe early events in metabolic processing of dietary fat. | 1999 | J. Lipid Res. | pmid:10508209 |
| Vargas CI and Ghaly ES | Kinetic release of theophylline from hydrophilic swellable matrices. | 1999 | Drug Dev Ind Pharm | pmid:10518245 |
| Chajès V et al. | Fatty-acid composition in serum phospholipids and risk of breast cancer: an incident case-control study in Sweden. | 1999 | Int. J. Cancer | pmid:10521790 |
| Xiao Y and Li X | Polyunsaturated fatty acids modify mouse hippocampal neuronal excitability during excitotoxic or convulsant stimulation. | 1999 | Brain Res. | pmid:10536218 |
| Mano T et al. | Proton MR spectroscopy of Sjögren-Larsson's syndrome. | 1999 | AJNR Am J Neuroradiol | pmid:10543638 |
| Kumar VB et al. | Changes in membrane fatty acids and delta-9 desaturase in senescence accelerated (SAMP8) mouse hippocampus with aging. | 1999 | Life Sci. | pmid:10573183 |
| Bretillon L et al. | Effects of conjugated linoleic acid isomers on the hepatic microsomal desaturation activities in vitro. | 1999 | Lipids | pmid:10574661 |
| Dürig T et al. | An investigation into the erosion behaviour of a high drug-load (85%) particulate system designed for an extended-release matrix tablet. Analysis of erosion kinetics in conjunction with variations in lubrication, porosity and compaction rate. | 1999 | J. Pharm. Pharmacol. | pmid:10579678 |
| Kikuchi K et al. | Fatty acid composition of choline and ethanolamine glycerophospholipid subclasses in heart tissue of mammals and migratory and demersal fish. | 1999 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:10582315 |
| Connor WE | Harbingers of coronary heart disease: dietary saturated fatty acids and cholesterol. Is chocolate benign because of its stearic acid content? | 1999 | Am. J. Clin. Nutr. | pmid:10584037 |
| Liu CY et al. | Synthesis and analytical properties of a novel columnar metallomesogenic polymer. | 1999 | J Chromatogr A | pmid:10588341 |
| Levy R and Herzberg GR | Hydrolysis of long-chain, n-3 fatty acid enriched chylomicrons by cardiac lipoprotein lipase. | 1999 | Can. J. Physiol. Pharmacol. | pmid:10588486 |
| Ceschel GC et al. | Optimization of a tablet containing chlorthalidone. | 1999 | Drug Dev Ind Pharm | pmid:10596354 |
| Wright LC et al. | The origin of 1H NMR-visible triacylglycerol in human neutrophils. Highfatty acid environments result in preferential sequestration of palmitic acid into plasma membrane triacylglycerol. | 2000 | Eur. J. Biochem. | pmid:10601852 |
| Klein J et al. | Fatty acid ethyl esters: a novel biologic marker for heavy in utero ethanol exposure: a case report. | 1999 | Ther Drug Monit | pmid:10604826 |
| González MS and Brenner RR | Fatty acid delta9-desaturation in the Triatoma infestans fat body: response to food and trehalose administrations. | 1999 | Lipids | pmid:10606043 |
| Weston WL and Morelli JG | Steroid rosacea in prepubertal children. | 2000 | Arch Pediatr Adolesc Med | pmid:10632252 |
| Rukkwamsuk T et al. | Interrelation of fatty acid composition in adipose tissue, serum, and liver of dairy cows during the development of fatty liver postpartum. | 2000 | J. Dairy Sci. | pmid:10659963 |
| Alonso A et al. | Lipid chain dynamics in stratum corneum studied by spin label electron paramagnetic resonance. | 2000 | Chem. Phys. Lipids | pmid:10669304 |
| Otz M and Thoma H | Effects of the metal type and the roughness of the die wall on the expended work for tablet ejection. | 2000 | Pharm Dev Technol | pmid:10669914 |