stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Muglia C et al. | Anaphylaxis to medications containing meat byproducts in an alpha-gal sensitized individual. | J Allergy Clin Immunol Pract | pmid:26003233 | |
| Gadegbeku CA et al. | Insulin's actions on plasma free fatty acids are normal in patients with stage 2 to 3 chronic kidney disease. | J Am Soc Hypertens | pmid:20409874 | |
| Klibanov AL et al. | Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow. | Contrast Media Mol Imaging | pmid:17191766 | |
| Garg M et al. | Hepatic de novo lipogenesis in stable low-birth-weight infants during exclusive breast milk feedings and during parenteral nutrition. | JPEN J Parenter Enteral Nutr | pmid:15772384 | |
| Adams ML et al. | Amphotericin B encapsulated in micelles based on poly(ethylene oxide)-block-poly(L-amino acid) derivatives exerts reduced in vitro hemolysis but maintains potent in vivo antifungal activity. | Biomacromolecules | pmid:12741794 | |
| Sobal G and Sinzinger H | Binding of [99mTc]chondroitin sulfate to scavenger receptors on human chondrocytes as compared to binding of oxidized [125I]LDL on human macrophages. | J. Recept. Signal Transduct. Res. | pmid:12503634 | |
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| Zaghloul AA et al. | Response surface methodology to obtain naproxen controlled release tablets from its microspheres with Eudragit L100-55. | J Microencapsul | pmid:11508770 | |
| Jenke D | Extraction of stearate salts from plastic materials used in pharmaceutical applications. | PDA J Pharm Sci Technol | pmid:21502020 | |
| Geslin JM et al. | [Allergic respiratory disorders and vein sclerosis with lauromacrogol 400]. | Therapie | pmid:15789831 | |
| Nelson B et al. | Effect of Dietary-Resistant Starch on Inhibition of Colonic Preneoplasia and Wnt Signaling in Azoxymethane-Induced Rodent Models. | Nutr Cancer | pmid:27367460 | |
| Best CA et al. | Method to assess fatty acid ethyl ester binding to albumin. | Alcohol Alcohol. | pmid:16554377 | |
| SWERN D et al. | Unsaturated alcohol esters of the 9,10-dihydroxystearic acids; preparation of elaidyl alcohol. | 1946 | J. Am. Chem. Soc. | pmid:20995013 |
| VOLD RD and PHILIPSON JM | The behavior of sodium stearate with cetane and water. | 1946 | J Phys Chem | pmid:21010917 |
| NIGHTINGALE G et al. | Effect of dihydroxystearic acid on vitamin K synthesis by rats. | 1947 | Arch Biochem | pmid:20291026 |
| GREGORY JN and SPINK JA | Lubricating properties of molecular layers of stearic acid and calcium stearate on metal surfaces. | 1947 | Nature | pmid:20291788 |
| WITTCOFF H and MILLER SE | Hydroxylated stearic acids; action of Prevost's reagent on oleic and elaidic esters; evidence for configuration of the hydroxy acids. | 1947 | J. Am. Chem. Soc. | pmid:18919716 |
| LIEN ML and MILLER CE | Magnesium stearate; a comparative study of commercial samples. | 1948 | J Am Pharm Assoc Am Pharm Assoc | pmid:18865175 |
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| McKAY AF and BADER AR | The preparation and properties of the eight diastereoisomers of 9,10,12,13-tetrahydroxystearic acid. | 1948 | J. Org. Chem. | pmid:18917710 |
| McKAY AF | Occurrence of stearic acid in bayberry tallow (wax). | 1948 | J. Org. Chem. | pmid:18917711 |
| WAYNE EJ et al. | The use of procaine penicillin with aluminium monostearate in adults. | 1949 | Br Med J | pmid:15407914 |
| EMERY JL and ROSE LM | The use in children of procaine penicillin with aluminium monostearate. | 1949 | Br Med J | pmid:18145953 |
| KITCHEN DK et al. | Serum concentrations following five treatment schedules with procaine penicillin in oil with aluminum monostearate. | 1949 | J. Invest. Dermatol. | pmid:18110581 |
| RIES HE et al. | Adsorption-desorption isotherm studies of catalysts; nitrogen and stearic acid adsorption by supported catalysts and their components. | 1949 | J Phys Colloid Chem | pmid:18130458 |
| KAGAN BM et al. | Studies of penicillin in pediatrics; III. Procaine penicillin G in sesame oil, in peanut oil with 2% aluminum monostearate and in water with sodium carboxymethylcellulose. | 1950 | Pediatrics | pmid:15417267 |
| KOSS FH and LIEBSCHNER K | [Significance of alpha alpha-dimethylstearic acid in tuberculosis]. | 1950 | Klin. Wochenschr. | pmid:14804983 |
| SPINK JA | Structure of stearic acid films on copper. | 1950 | Nature | pmid:15416726 |
| ZABIN I | On the conversion of palmitic acid to stearic acid in animal tissues. | 1951 | J. Biol. Chem. | pmid:14832248 |
| KIVITS M | [Frambesia therapy with oil procaine-penicillin with aluminium stearate]. | 1951 | Ann Soc Belg Med Trop (1920) | pmid:14838448 |
| WEITZEL G and WOJAHN J | [Biochemistry of branched carboxylic acids. VII. Preparation of racemic monomethyl-stearic acids]. | 1951 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:14860764 |
| WEINMAN EO et al. | Conversion of first and sixth carbons of stearic acid to carbon dioxide by rats. | 1951 | J. Biol. Chem. | pmid:14861197 |
| BERNHARD K and GLOOR U | [Some other fatty acids with vitamin F effect]. | 1953 | Helv Physiol Pharmacol Acta | pmid:13128629 |
| MUNZEL K and AMMANN R | [On the washable fat-in-water ointments. I. Description and characteristics of fat-in-water ointments]. | 1953 | Pharm Acta Helv | pmid:13133659 |
| DOXIADIS SA | Procaine penicillin with aluminium monostearate; infrequent injections for children. | 1953 | Lancet | pmid:13085786 |
| VALADE P and COSTE E | [Toxicity of the organic lead salts; experimental study]. | 1953 | Arch Mal Prof | pmid:13149301 |
| BUTCHER EO | Penetration of radioactive stearic acid into the skin of the rat. | 1953 | J. Invest. Dermatol. | pmid:13096866 |
| SKOU JC | Local anaesthetics. V. The action of local anaesthetics on monomolecular layers of stearic acid. | 1954 | Acta Pharmacol Toxicol (Copenh) | pmid:14398295 |
| MUNZEL K and AMMANN R | [Washable oil-water ointments. V. Complex-emulsified ointments; differences between stearate- and complex-emulsified ointments]. | 1954 | Pharm Acta Helv | pmid:13194353 |
| SCRIBANTE P and FAVARGER P | [Studies on digestibility of stearic acid and its glyceric esters in rat]. | 1954 | Helv Physiol Pharmacol Acta | pmid:13201008 |
| MUNZEL K and AMMANN R | [On washable fat-in-water ointments. IV. Stearate ointments]. | 1954 | Pharm Acta Helv | pmid:13166515 |
| DUNCOMBE WG and GLASCOCK RF | The contribution of dietary stearic acid to milk fat. | 1954 | Biochem. J. | pmid:13172205 |
| BERGSTROM S et al. | Intestinal absorption and metabolism of 2:2-dimethylstearic acid in the rat. | 1954 | Biochem. J. | pmid:13230010 |
| GLASCOCK RF and REINIUS LR | Location of tritium in stearic acid produced by catalytic tritiation of elaidic acid. | 1954 | Biochem. J. | pmid:13230049 |
| SHAFER JK and SMITH CA | Treatment of early infectious syphilis with N,N'-dibenzylethylenediamine dipenicillin G; a second report. | 1954 | Bull. World Health Organ. | pmid:13182589 |
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| MUNZEL K and AMMANN R | [Contributions on the character of water-soluble fatty ointments. X. Quasiviscosity determination of stearate ointments]. | 1955 | Pharm Acta Helv | pmid:13289260 |
| SULMAN FG | A note on the resorption and excretion of riboflavine from aluminium monostearate suspensions in the rat. | 1955 | J. Pharm. Pharmacol. | pmid:14392601 |
| POLYOXYETHYLENE stearates in food. | 1955 | Nutr. Rev. | pmid:14394517 |