stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Zackler J et al. | A mass screening program for the detection of gonorrhea. | 1972 | Am. J. Obstet. Gynecol. | pmid:4623083 |
Wahle KW and Garton GA | Desaturation of stearate by sheep tissue microsomal preparations. | 1972 | Biochem. J. | pmid:4643297 |
Conte U et al. | The effect of magnesium stearate and polytetrafluoroethylene as lubricants in direct compression of acetylsalicylic acid. | 1972 | Farmaco Prat | pmid:5049531 |
Lesslauer W and Blasie JK | Direct determination of the structure of barium stearate multilayers by x-ray diffraction. | 1972 | Biophys. J. | pmid:5057749 |
Price CJ and Rowe CE | Stimulation of the production of unesterified fatty acids in nerve endings of guinea-pig brain in vitro by noradrenaline and 5-hydroxytryptamine. | 1972 | Biochem. J. | pmid:5075269 |
Miyake Y et al. | [Studies on packing-property of pharmaceutical powders. II. Compacting phenomenon of pharmaceutical powders in the course of mixing with calcium stearate]. | 1972 | Yakugaku Zasshi | pmid:4675495 |
Kabara JJ et al. | Fatty acids and derivatives as antimicrobial agents. | 1972 | Antimicrob. Agents Chemother. | pmid:4670656 |
Butcher AE and Jones TM | Some physical characteristics of magnesium stearate. | 1972 | J. Pharm. Pharmacol. | pmid:4144914 |
Ryan DC et al. | Estolate and stearate forms of erythromycin in the treatment of acute beta haemolytic streptococcal pharyngitis. | 1973 | Med. J. Aust. | pmid:4568626 |
Bond JM et al. | The second international reference preparation of procaine benzylpenicillin in oil with aluminium monostearate. | 1973 | Bull. World Health Organ. | pmid:4541152 |
Arya OP and Bosa CB | In search of an ideal single-session penicillin schedule for the treatment of gonorrhoea in Uganda. | 1973 | Br J Vener Dis | pmid:4748409 |
McLeay A and Cooke P | Estolate and stearate forms of erythromycin in beta-haemolytic streptococcal pharyngitis. | 1973 | Med. J. Aust. | pmid:4694278 |
Norwitz G and Gordon H | Determination of lithium stearate in sebacate-based lubricants by atomic absorption. | 1973 | Talanta | pmid:18961363 |
Miyake Y et al. | [Studies on packing-property of pharmaceutical powders. 3. Influence of calcium stearate content on compacting phenomenon of pharmaceutical powders (author's transl)]. | 1973 | Yakugaku Zasshi | pmid:4797567 |
Antimicrobial efficacy of erythromycin stearate. A report from the general Practitioner Research Group. | 1974 | Practitioner | pmid:4591200 | |
Caldwell HC | Dissolution of lithium and magnesium from lithium carbonate capsules containing magnesium stearate. | 1974 | J Pharm Sci | pmid:4830001 |
Beleslin DB et al. | Hyperthermic effect of palmitate sodium, stearate sodium and oleate sodium injected into the cerebral ventricles of conscious cats. | 1974 | Neuropharmacology | pmid:4840846 |
Kasuya M et al. | Toxic effect of cadmium stearate on rat cerebellum in culture. | 1974 | Bull Environ Contam Toxicol | pmid:4474041 |
Wood R | Sterospecific analysis of hepatoma, host liver, and normal rat liver triglycerides from animals on chow and fat free diets. | 1975 | Lipids | pmid:167260 |
Iot T et al. | Synthesis of a new phosphatidylserine spin-label and calcium-induced lateral phase separation in phosphatidylserine-phosphatidylcholine membranes. | 1975 | Biochemistry | pmid:167814 |